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Citations for Tocris :
701 - 750 of 861 citations for 6 METHOXY 3 NITROPYRIDINE 2 CARBONITRILE since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2023Quote: iPSCs were first differentiated into iAT2s and passaged as above in 3D cultures in iAT2 medium (CK+DCI) supplemented for the first 3 days after passaging with 10 uM Y-27632 (Tocris). To generate iAT1s ...
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bioRxiv - Neuroscience 2023Quote: ... Extracellular action potentials were recorded in 3 independent cultures for either genotype in the presence of 50nM nifedipine (Tocris Bioscience) or vehicle using the MaestroPro (Axion Biosystems ...
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bioRxiv - Bioengineering 2023Quote: ... The media were changed at day 3 to remove the ROCK inhibitor and to add 10 µM DAPT (Tocris Bioscience), which remained until day 7 ...
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bioRxiv - Neuroscience 2019Quote: ... and 2-(4-morpholino)-8-phenyl-4H-1-benzopyran-4-one (LY294002, 10µM) (Tocris) were dissolved in DMSO and then added in the external solution at a final concentration of DMSO of 0.001-0.04% ...
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bioRxiv - Neuroscience 2020Quote: ... Cells were inhibited by pre exposure for 2 hours with Edelfosine (10 µM) (Tocris) or U73122 (5 µM ...
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bioRxiv - Neuroscience 2020Quote: ... Cells were inhibited by pre exposure for 2 hours with Edelfosine (10 µM) (Tocris) or U73122 (5 µM ...
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bioRxiv - Neuroscience 2021Quote: ... L-(+)-2-amino-4-phosphonobutyric acid (L-AP4, 50 μM, Tocris Bioscience, Bristol, UK) were diluted to the appropriate concentration from stock solutions and added to the bath through the perfusion system for 10 minutes before recordings ...
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bioRxiv - Neuroscience 2021Quote: ... L-(+)-2-amino-4-phosphonobutyric acid (L-AP4, 50 μM, Tocris Bioscience, Bristol, UK) were diluted to the appropriate concentration from stock solutions and added to the Ames medium before recordings.
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bioRxiv - Cell Biology 2021Quote: ... Raptor ER-Cre mice and littermate controls were treated with 2 mg tamoxifen (Tocris) in 100 μL corn oil via gavage on 5 consecutive days ...
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bioRxiv - Biochemistry 2022Quote: ... 0.055 mM 2-mercaptoethanol and 1μg/ml Insulin) plus 1.5 μM Dorsomorphin (Tocris Bioscience) and 10 μM SB431542 (Stemgent ...
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bioRxiv - Immunology 2020Quote: ... then patterned towards midgut in RPMI+2%B27 with 3μM CHIR99021 (Wnt agonist, TOCRIS) and 500ng/ml recombinant FGF4 (R&D ...
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bioRxiv - Neuroscience 2021Quote: ... half of the neuronal cultures were treated at DIV13 with 2 μM TTX (Tocris) for 48 h.
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bioRxiv - Neuroscience 2020Quote: ... DL-2-Amino-5-phosphonopentanoic acid sodium salt (AP5, Cat. No. 3693, Tocris, UK), (-)-Bicuculline methochloride (Cat ...
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bioRxiv - Developmental Biology 2021Quote: ... the culture medium was changed to E6 medium supplemented with 2 μM XAV939 (Tocris Bioscience ...
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bioRxiv - Neuroscience 2021Quote: We inhibited LRRK2 kinase activity with the selective LRRK2 inhibitor MLi-2 (Tocris 5756). MLi-2 has low solubility in water ...
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bioRxiv - Genomics 2021Quote: ... followed by 2 uM of the Wnt signaling inhibitor Wnt-C59 (5148, Tocris Bioscience). Cells start to spontaneously beat between days 7-10 ...
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bioRxiv - Neuroscience 2022Quote: ... and L-2-amino-5-phosphonopentanoic acid (APV, an NMDA receptor blocker) from Tocris. APV ...
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bioRxiv - Neuroscience 2023Quote: ... and 50 μM 2-amino-5-phosphonopentanoic acid (D-AP5; Tocris Bioscience, Cambridge, UK) to avoid spontaneous network activation ...
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bioRxiv - Neuroscience 2022Quote: ... and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5, TOCRIS bioscience #0105). NH4Cl perfusions were done with 50 mM NH4Cl in substitution of 50 mM NaCl (pH 7.4) ...
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bioRxiv - Neuroscience 2024Quote: ... L-(+)-2-amino-4-phosphonobutyric acid (L-AP4, 50 mM, Tocris Bioscience, Bristol, UK) was added.
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bioRxiv - Cell Biology 2020Quote: ... and diabetic NOD mice (14-26 weeks; n=3) were intra-peritoneally injected with 50mg/kg of Chloroquine diphosphate (Tocris #4109). Two hours post injection ...
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bioRxiv - Cell Biology 2021Quote: Receptors were stimulated as follows: human Angiotensin 1 receptor (AT1R) with Angiotensin II (AngII; Tocris 4474-91-3, in measuring buffer), human β2 adrenergic receptor (β2ADR ...
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bioRxiv - Pharmacology and Toxicology 2022Quote: ... supplemented with 100 ng/mL Activin A (R&D, Minneapolis, MN, USA) and 3–5 µM CHIR99021 (Tocris Bioscience, Bristol, UK) (differentiation day 0 ...
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bioRxiv - Neuroscience 2022Quote: ... 12-well plates at 3-4 × 105 cells/well in mTeSR1 with 10 µM rho-kinase inhibitor (Y-27632; Tocris, 1254). Medium without the inhibitor was replaced daily until the cells reach 80-100% confluency ...
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bioRxiv - Cell Biology 2020Quote: ... into fibronectin-coated wells of two 96 well plates per biological replicate to assess proliferation on day 0 (D0) and day 3 (D3) in the presence or absence of 10 μM RARβ antagonist LE135 (Tocris Bioscience) using the cell viability MTS assay ...
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bioRxiv - Neuroscience 2023Quote: ... 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid (DQP 1105, 10 μM dissolved in DMSO; Tocris Bioscience), or 6-Cyano-7-nitroquinoxaline-2,3-dione disodium (CNQX ...
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bioRxiv - Biochemistry 2022Quote: ... Positive clones were analyzed by Sanger sequencing with primers #3 and #4 (Integrated DNA Technologies, Supplementary Table S5) and degradation upon dTAG-13 (Tocris, 6605) treatment was confirmed by Western Blot by a-Chaf1a antibody (65) ...
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bioRxiv - Pharmacology and Toxicology 2019Quote: ... or 2 mM (R,S)-3,5-DHPG (mGlu1/5 agonist, Tocris 0805 and 0342 respectively), and the astrocyte marker Sulforhodamine 101 (40 μM ...
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bioRxiv - Neuroscience 2020Quote: ... Animals were then immobilized by immersion in a solution of 2 mM pancurionium dibromide (Tocris) in 0.1X MBSH for 2-5 min ...
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bioRxiv - Neuroscience 2019Quote: ... The exogenous DREADD ligand clozapine-N-oxide CNO (2 mg/kg) was purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2021Quote: ... 1,2-bis(2-aminophenoxy)ethane-N,N,N’,N’-tetraacetic acid (BAPTA, 50 µM, Tocris); and 1,2-Bis(2-aminophenoxy)ethane-N,N,N’,N’-tetra-acetic acid tetrakis (acetoxymethylester ...
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bioRxiv - Neuroscience 2021Quote: ... 25 μM of d-(-)-2-amino-5-phosphonopentanoic acid (D-AP5, 0106, Tocris Bioscience, UK), and 10 μM of SR95531 (SR ...
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bioRxiv - Cell Biology 2021Quote: ... and human vasopressin type 2 receptor (V2R) with [Arg8]-vasopressin (AVP; Tocris 2935, in water). The transfected β-arrestins are of bovine origin ...
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bioRxiv - Neuroscience 2019Quote: ... D-2-amino-5-phosphonovalerate (“D-AP5”, 50 mM in PBS, Tocris Cat No 0106); Retigabine (100 mM in DMSO ...
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bioRxiv - Genomics 2020Quote: ... supplemented with SMAD inhibitors (DMH-1 2 μM Tocris, Cat.: #4423; SB431542-10 μM Tocris, Cat. ...
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bioRxiv - Genomics 2021Quote: ... 1 µM DMH1-HCl (in house synthesized, Vanderbilt University) and 240 nM IWP-2 (Tocris). On day 8 of differentiation ...
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bioRxiv - Biochemistry 2022Quote: ... and E3 ligase recruiter building blocks thalidomide - linker 2 (#6468/25) were purchased from Tocris Bioscience (Minneapolis ...
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The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfallsbioRxiv - Neuroscience 2023Quote: ... a single submaximal concentration (10 µM) of WIN-55,212-2 or HU-210 (Tocris #0966) was used ...
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bioRxiv - Neuroscience 2023Quote: ... and exposure to a cocktail of small molecules containing 2 μM each of Dorsomorphin (Tocris), A83-01 (Tocris ...
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bioRxiv - Cell Biology 2023Quote: ... the samples were blocked for 2 hours in HBSS with 4% BSA (Tocris BioScience, #5217). Incubation with primary antibody rabbit anti progesterone receptor (1:500 in 4% BSA ...
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bioRxiv - Neuroscience 2023Quote: ... organoids were placed in HEPES buffer containing CNQX/APV (2 µM/50 µM, Tocris Bioscience) and imaged immediately.
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bioRxiv - Genomics 2023Quote: ... spent media was replaced with fresh CDM containing 2 µM Wnt-C59 (5148, Tocris Bioscience). CDM was used to replace media on Days 5 ...
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HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesisbioRxiv - Cell Biology 2023Quote: ... the medium was replaced with differentiation medium containing 5 μM IWP-2 (TOCRIS, Cat.# 3533), a Wnt inhibitor ...
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bioRxiv - Neuroscience 2024Quote: ... USA) and superfused with ACSF containing 2 mM CaCl2 and 20 µM bicuculline methiodide (Tocris) at a rate of 3 – 4 ml/min at RT ...
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bioRxiv - Neuroscience 2021Quote: ... n=20) group were randomized to receive either saline or GLP-1R antagonist Exendin-3(9-39)amide (Ex-9) (Tocris Bioscience, UK) (85 μg/kg dissolved in saline ...
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bioRxiv - Genomics 2022Quote: ... iPS cells were grown to 80– 90% confluence and changed into CM Media supplemented with 3 μM CHIR99021 (Tocris Biosciences, Bristol, UK) for 2 days ...
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bioRxiv - Neuroscience 2020Quote: ... co-applied with the competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid AMPA/kainate receptor antagonist CNQX (Tocris; 20 μM) (n=13) ...
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bioRxiv - Cancer Biology 2022Quote: ... Proteins were then transferred onto PVDF membranes (Cytiva, Catalog #: 10600023) using a wet transfer approach and membranes were then blocked with 3% bovine serum albumin (Tocris, Catalog #: 5217) and probed for CDC42 (Cell Signaling Technology ...
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bioRxiv - Neuroscience 2021Quote: ... 6R)-4-Amino-2-oxabicyclo [3.1.0] hexane-4,6-dicarboxylic acid disodium salt (LY379268, 100 µM, Tocris); calmidazolium chloride (CMZ ...
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bioRxiv - Neuroscience 2020Quote: ... WIN 55,212-2 (WIN, 0.5 µg/0.5-µL infusion/hemisphere; n = 11; Tocris Bioscience, Minneapolis, MN) or VEH (10% DMSO ...