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Citations for Tocris :
701 - 742 of 742 citations for 6 ETHYL 4 HYDROXY QUINOLINE 3 CARBOXYLIC ACID since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2020Quote: ... and diabetic NOD mice (14-26 weeks; n=3) were intra-peritoneally injected with 50mg/kg of Chloroquine diphosphate (Tocris #4109). Two hours post injection ...
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bioRxiv - Cell Biology 2021Quote: Receptors were stimulated as follows: human Angiotensin 1 receptor (AT1R) with Angiotensin II (AngII; Tocris 4474-91-3, in measuring buffer), human β2 adrenergic receptor (β2ADR ...
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bioRxiv - Pharmacology and Toxicology 2022Quote: ... supplemented with 100 ng/mL Activin A (R&D, Minneapolis, MN, USA) and 3–5 µM CHIR99021 (Tocris Bioscience, Bristol, UK) (differentiation day 0 ...
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bioRxiv - Systems Biology 2020Quote: ... On Day 3 we changed the medium to RPMI + 2% B-27 (minus insulin) + 1uM Xav 939 (Tocris Bioscience, cat. 3748) and incubated the cells for 48 hours ...
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bioRxiv - Cell Biology 2020Quote: ... into fibronectin-coated wells of two 96 well plates per biological replicate to assess proliferation on day 0 (D0) and day 3 (D3) in the presence or absence of 10 μM RARβ antagonist LE135 (Tocris Bioscience) using the cell viability MTS assay ...
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bioRxiv - Physiology 2023Quote: ... PAH was induced by a single subcutaneous injection of SU5416 (SU:3-(3,5-dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydroindol-2-one) (Tocris, Bristol, United Kingdom) in 0.5% carboxymethyl cellulose followed by 3-weeks chronic hypoxia (9-10% O2) ...
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bioRxiv - Neuroscience 2019Quote: ... a final group of animals (n=4) received a DBB infusion of K-234 (1 nmol/0.5 µl/per side; Tocris Bioscience ...
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bioRxiv - Neuroscience 2022Quote: ... and (2S)-1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-[(4-pyridinylmethyl)amino]-1-butanone hydrochloride (TCS-OX2-29) were purchased from Tocris Bioscience ...
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bioRxiv - Developmental Biology 2022Quote: ... zebrafish embryos were dechorionated with 1mg/ml pronase at 9 hpf and washed thoroughly with fresh Danieau’s buffer before being treated with 10μM (Z)-4-hydroxytamoxifen (#3412, Tocris, UK) for 2h at 28°C in the dark ...
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bioRxiv - Neuroscience 2023Quote: ... L-glutamate was locally photo-released from 1 mM 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-glutamate, TOCRIS) using an OPTOLED pulse of 1 ms at 365 nM wavelength ...
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bioRxiv - Neuroscience 2021Quote: ... n=20) group were randomized to receive either saline or GLP-1R antagonist Exendin-3(9-39)amide (Ex-9) (Tocris Bioscience, UK) (85 μg/kg dissolved in saline ...
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bioRxiv - Genomics 2022Quote: ... iPS cells were grown to 80– 90% confluence and changed into CM Media supplemented with 3 μM CHIR99021 (Tocris Biosciences, Bristol, UK) for 2 days ...
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bioRxiv - Genomics 2020Quote: ... supplemented with SMAD inhibitors (DMH-1 2 μM Tocris, Cat.: #4423; SB431542-10 μM Tocris, Cat.: #1614 and CHIR99021 3 μM, CHIR Tocris, Cat.: #4423).
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bioRxiv - Cancer Biology 2022Quote: ... Proteins were then transferred onto PVDF membranes (Cytiva, Catalog #: 10600023) using a wet transfer approach and membranes were then blocked with 3% bovine serum albumin (Tocris, Catalog #: 5217) and probed for CDC42 (Cell Signaling Technology ...
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bioRxiv - Bioengineering 2021Quote: ... supplemented with FGF-2 (20 ng ml−1), Activin-A (50 ng ml−1), BMP-4 (10 ng ml−1, R&D) and LY294002 (10 mM Tocris). Media was changed again after 42 hours to CDM-BSA supplemented with FGF-2 (8 ng ml−1) ...
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bioRxiv - Cell Biology 2021Quote: ... flow cytometer, and the fractions of stained cells were quantified using FloJo 10.6, with Staurosporine (4 h, 5 μM) (Tocris, 1285) used as a positive control for cell death and to help establish gating of the sorted cells.
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bioRxiv - Neuroscience 2021Quote: Structural plasticity of dendritic spines was stimulated through uncaging of 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris) using a Ti ...
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bioRxiv - Developmental Biology 2021Quote: ... Neural progenitors were briefly washed (with DMEM/F12) and were then treated with CDM2 basal media supplemented with CHIR99021 (4 μM; Tocris), SB-505124 (2 μM ...
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bioRxiv - Neuroscience 2020Quote: The FPR2 agonist Compound-43 (N-(4-Chlorophenyl)-N-[2,3-dihydro-1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]-urea) and antagonist WRW4 (Trp-Arg-Trp-Trp-Trp-NH2) were purchased from Tocris Ltd ...
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bioRxiv - Microbiology 2022Quote: ... 3 μl of 10 mM of NBD-(linezolid-7-nitrobenz-2-oxa-1,3-diazol-4-yl)-amino-D-alanine (NADA) (Tocris Bioscience) was added to the resuspension ...
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bioRxiv - Neuroscience 2022Quote: ... we used a cocktail of the mGluR-4 antagonist [0.5 mM MSOP: (RS)-α-methylserine-O-phosphate obtained from Tocris Biosciences] with either umami at 300 mM or MSGa at 600 mM ...
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bioRxiv - Cancer Biology 2022Quote: ... and plated at 60,000 cells/cm2 in N2B27 medium supplemented with 20 ng/ml of FGF2 (Cat# 233-FB/CF, R&D) and 4 μM of CHIR 99021 (Cat# 4423, Tocris) and 10 μM of Rock Inhibitor (Y-27632 ...
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bioRxiv - Neuroscience 2023Quote: ... and (3-chloro-4-fluoro-N-[(4-([2-(phenylcarbonyl)hydrazino]carbonyl) phenyl)methyl]benzene-sulfonamide) (TCN-201) (Hansen et al., 2012)were obtained from Tocris Bioscience ...
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bioRxiv - Neuroscience 2023Quote: ... was set to 720 nm and used to uncage 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris). Up to four spines in separate regions of interest (ROI ...
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bioRxiv - Neuroscience 2023Quote: ... Cells were then rinsed with 3x with PBS before fixation with 4% paraformaldehyde in PBS with 10 μg/ml Hoechest 33342 (Tocris) for 30 min at RT ...
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bioRxiv - Neuroscience 2024Quote: ... 1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide (WS-12) was purchased from Tocris Bioscience and prepared in a DMSO stock (20 mM) ...
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bioRxiv - Neuroscience 2021Quote: ... Alexa-fluorophore conjugated secondary antibodies were added in blocking solution for 1 hour at 4°C followed by treatment with Methoxy-X04 (Tocris, 4920) for 15 minutes at room temperature to label amyloid-beta plaques ...
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bioRxiv - Developmental Biology 2019Quote: ... From day 2 to day 4 the medium was additionally supplemented with BMP and TGFβ inhibitors (Noggin, Peprotech and SB431542, Tocris Bioscience). Treatment with MEK inhibitor (PD184352 ...
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bioRxiv - Neuroscience 2020Quote: ... ACSF of similar composition to the normal ACSF but with increased concentration (4 mM) of MgCl2 and CaCl2 and supplemented with 100μM MNI-caged glutamate (Tocris Bioscience, UK) for glutamate uncaging experiments ...
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bioRxiv - Neuroscience 2022Quote: ... where they were immobilized under a nylon mesh (Smart Ephys, SHD-26GH/10) and paralyzed by injecting 0.5 nL of bungarotoxin at 0.5 mM (Tocris, #110.32-79-4) in the trunk musculature ...
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Neuroscience 2023Quote: ... the α7 nAChR specific agonist PNU 282987 (1.6 μg total dose; 0.2 μL volume of 4 μg/μL per side; PNU 282987, Tocris, Ellisville, MO, USA), or vehicle (artificial cerebrospinal fluid [aCSF] or 50/50% aCSF/dimethylsulfoxide [DMSO] ...
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bioRxiv - Neuroscience 2023Quote: ... Firing rates of individual channels were compared before and after treatment with potassium channel blocker 4-AP (50 μM; Tocris, 0940), sodium channel blocker TTX (1 μM ...
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bioRxiv - Developmental Biology 2022Quote: ... and 1% Pen/Strep) +2iLIF (10 ng/ml leukemia inhibitory factor + 3 μM CHIR99021 + 1 μM PD0325901 from Tocris, Cat. # 4423 and 4192, respectively). The cells were grown on 0.1% gelatin-coated dishes and usually seeded at a density of 0.5–1.5 × 104/cm2 ...
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bioRxiv - Pharmacology and Toxicology 2019Quote: ... The P2Y2R antagonist AR-C118925XX (5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide) was obtained from Tocris (Abingdon, UK). Subsequent dilutions of receptor ligand and other reagents were made in Krebs-Ringer Glucose phosphate buffer (KRG ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... as well as the P2Y2R antagonist AR-C118925XX (5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide) were obtained from Tocris (Abingdon, UK). Subsequent dilutions of receptor ligand and other reagents were made in Krebs-Ringer Glucose phosphate buffer (KRG ...
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bioRxiv - Neuroscience 2023Quote: ... Drug treatments correspond to a single dose of cocaine hydrochloride at 20 mg/kg (Medisca, cat# 53-21-4, Canada) or D-amphetamine sulfate at 5 mg/kg (Tocris, 2813, UK) at doses known to increase locomotion87 ...
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bioRxiv - Neuroscience 2023Quote: ... was selected by qualifying the presence of innervated cancer spheroids at various heights within the gel layer before stimulation with either 4 µM Bradykinin (Tocris/Biotechne, #3004) or 1 µM Capsaicin (Tocris/Biotechne ...
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bioRxiv - Neuroscience 2020Quote: ... They were left drug-free for 3 weeks before chronic daily treatment with vehicle (NaCl 0.9%) or VU0155041 (Tocris, Bristol, UK; 2.5 or 5 mg/kg, i.p.) started ...
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bioRxiv - Developmental Biology 2021Quote: ... (15) ESC were grown in N2B27 media supplemented with 2i/LIF (1 mM PD0325901, 3 mM CHIR99021, both from Tocris and 1:500 LIF, made in house). N2B27 media consisted of a 1:1 mix of DMEM/F12 and Neurobasal Medium ...
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bioRxiv - Physiology 2024Quote: ... Drugs were added from the following stock solutions: (2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboximide (WS-12, Tocris #3040, Bio-Techne Ltd, Abingdon, UK) 5 mM in ethanol ...
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bioRxiv - Neuroscience 2023Quote: ... we tested effects of an inhibitor (the spider toxin GsMTX 4; Tocris #4912 stock 50 μM in DMSO and the Piezo1 channel activator Yoda1 (Tocris 6586 10 and 20 uM, stock 20 mM in DMSO).