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Citations for Tocris :
651 - 700 of 827 citations for 5 Pyrimidinecarboxaldehyde 2 amino oxime 9CI since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Molecular Biology 2020Quote: ... and 200 μL of flow buffer supplemented to a final concentration of 5 μM DFHO dye (TOCRIS Bioscience) was added prior to analysis by flow cytometry.
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bioRxiv - Neuroscience 2019Quote: N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (AM251, 3µM) (Tocris) was dissolved in ethanol and then added in the external solution at a final concentration of ethanol of 0.015% ...
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bioRxiv - Genomics 2022Quote: ... and cultured for 24 hours in iPS media supplemented with 5 μM Y-27632 (Tocris Biosciences, Bristol, UK) prior to maintenance in iPS media ...
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bioRxiv - Neuroscience 2023Quote: Gabra6-Cre::Thy1-ChR2::DREADD mice received intra-peritoneal injections of CNO (5 mg/kg; Tocris Bioscience, #4936) 60-90 min before starting eyeblink experiments.
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bioRxiv - Cell Biology 2023Quote: ... differentiation was initiated by treating the hESCs with cardiomyocyte differentiation basal medium (CDBM) with 5 mM CHIR99021 (Tocris) to activate Wnt/β-catenin signaling and form the mesendoderm layer ...
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bioRxiv - Cancer Biology 2023Quote: ... the STING inhibitor C-176 was used at a final concentration of 5 µM (Tocris Bioscience (Bio-Techne), Bristol ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... or the α7-selective nAChR antagonist methyllycaconitine citrate (MLA; 5 mg/kg in sterile saline; Tocris, Bristol, UK). These pharmacological reagents were injected s.c ...
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Safety and efficacy of C9ORF72-repeat RNA nuclear export inhibition in amyotrophic lateral sclerosisbioRxiv - Systems Biology 2021Quote: ... supplemented with SMAD inhibitors (DMH-1 2 µM; SB431542-10 µM and CHIR99021 3 µM [ [Tocris]). The medium was changed every day for 6 days ...
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bioRxiv - Neuroscience 2020Quote: ... Readings were taken before and 3–4 min after application of 20 μM 2-AG (Tocris) to activate CB1R or the eCB sensor.
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bioRxiv - Neuroscience 2020Quote: ... JNJ16259685 and 2-Methyl-6-(phenylethynyl)pyridine (MPEP) hydrochloride were purchased from Tocris (Minneapolis MN, USA). (±)-Sulpiride was purchased from MilliporeSigma ...
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bioRxiv - Neuroscience 2020Quote: ... WIN 55,212-2 (WIN, 0.5 µg/0.5-µL infusion/hemisphere; n = 11; Tocris Bioscience, Minneapolis, MN) or VEH (10% DMSO ...
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bioRxiv - Cancer Biology 2022Quote: ... One hour before dsDNA transfection cells were pre-treated with 2 µM NU7441 (#3712, Biotechne/Tocris) in OptiMEM and were subsequently transfected with dsDNA (1 µg/ml) ...
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bioRxiv - Neuroscience 2021Quote: ... 3-((±)2-carboxypiperazin-4yl) propyl-1-phosphate (CPP, NMDA receptor antagonist, 20 μM; Tocris Bioscience, UK) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Cancer Biology 2022Quote: ... 2% Sodium deoxycholate and 0.2% SDS including protease inhibitors (Aprotinin (TOCRIS Bioscience Cat. no. 4139/10) Leupeptin (Fisher Scientific ...
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bioRxiv - Genomics 2019Quote: ... the previously described medium was replaced with heart medium containing 2 μM Wnt-C59 (Tocris, 5148). On days 5 ...
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bioRxiv - Developmental Biology 2021Quote: ... Lin- c-Kit+ cells were sorted into 2%FCS-PBS with 100µM IWR-1 (Tocris, 3532) or control vehicle ...
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bioRxiv - Microbiology 2020Quote: ... cells were pretreated for 3h before infection with Tautomycetin (0.8 μM, Tocris Bioscience, 119757-73-2) or Okadaic acid (0.1 μM ...
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bioRxiv - Molecular Biology 2021Quote: Cells were treated for 2 hrs with vehicle (DMSO) or with 250 nM Torin1 (Tocris Biosciences), or for 1 hr with 50 μM Ly29004 (Tocris Biosciences ...
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bioRxiv - Neuroscience 2022Quote: ... we slowly infused 200 nl of the GABAA receptor agonist muscimol (Tocris; 2 μM in saline) into the target area using a micro-syringe pump (KD Scientific ...
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bioRxiv - Neuroscience 2022Quote: The β3AR-selective antagonist SR59230A (2 mg/kg/day or 10 mg/kg/day; Tocris Bioscience) or vehicle (2:3 ratio of DMSO:0.9% saline ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Biochemistry 2023Quote: ... Cannabinoid ligands (anandamide [AEA], 2-arachydonyl-glycerol [2AG], SR144528, HU210, HU308, cannabinol) were obtained from Tocris Bioscience and dissolved in DMSO to a storage concentration of 10 mM ...
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bioRxiv - Developmental Biology 2023Quote: ... at a density of 2 × 103 cells/cm2 with 10µM ROCK inhibitor (Y-27632; Tocris, 1254) added in culture medium for 1 day after hESCs passaging ...
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bioRxiv - Neuroscience 2024Quote: ... The following competitive antagonists were employed for microscopical experiments: trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline (L-689-560; Tocris); 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone (L-701-324 ...
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bioRxiv - Cell Biology 2024Quote: ... the WNT signaling inhibitor IWP-2 (2μM in DMSO, day 21-42, Tocris Bioscience, Bristol, UK), the hedgehog inhibitor cyclopamine (10μM in DMSO ...
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bioRxiv - Developmental Biology 2024Quote: ... Cells were treated as control or with 2 µM DDR1 inhibitor DDR1-in-1 (Tocris 5077) or 5 µM RUNX1 inhibitor AI-10-104 (Aobious AOB17076) ...
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bioRxiv - Cell Biology 2020Quote: ... 0.5 mL fresh RPMI 1640 containing B-27 supplement minus insulin was added to 0.5 mL conditioned (old) medium and added to cells along with 5 µM IWP2 (Tocris). Medium was aspirated at Day 5 and replenished with fresh RPMI 1640 containing B-27 supplement minus insulin ...
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bioRxiv - Cell Biology 2020Quote: ... Electroporated cells were seeded in fresh E8 media containing 5 μM Y-27632 dihydrochloride (a selective ROCK inhibitor, Tocris) and allowed to recover for 48 hours before antibiotic selection.
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bioRxiv - Neuroscience 2019Quote: ... and substracted from background noise by detecting events in the last 4 seconds of 5 EPSCs at 0.2 Hz in 3 mM NBQX (Tocris) in extracellular solution.
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bioRxiv - Neuroscience 2021Quote: ... All neurons were recorded in control conditions and after >5 min of bath application of 1 µM DHβE (Tocris).
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bioRxiv - Neuroscience 2021Quote: ... AM 251 (N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide) from Tocris and ...
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bioRxiv - Neuroscience 2019Quote: Mice received an IP injection of vehicle or CNO (5 mg/kg; Tocris or National Institute of Mental Health) or vehicle (1% DMSO in saline) ...
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bioRxiv - Genetics 2021Quote: ... Cells were then incubated in RPMI/B27 (-Insulin) for 24 hours before changing media to 5 μM IWP2 (Tocris) in RPMI/B27(-Insulin) ...
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bioRxiv - Molecular Biology 2021Quote: ... Calu-3 cells were preincubated for 1 h with medium (50 μl/well) containing either increasing concentrations of Camostat (0.5, 5 or 50 μM; Tocris) or dimethyl sulfoxide (solvent control ...
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bioRxiv - Neuroscience 2023Quote: ... 5 mM QX314 was added into the intracellular pipette solution while GABAA receptor antagonist picrotoxin (PTX, 50 μM, Tocris), GABAB receptor antagonist CGP55845 (3 μM ...
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bioRxiv - Neuroscience 2023Quote: ... slices were incubated in recording ACSF supplemented with 5 μM 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX, Tocris, 1045) and 100 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Microbiology 2023Quote: ... Monolayers were then treated with increasing doses (0, 0.5, 1, 3, 5, 7, 10, 20 μM) of Ro 08-2750 (TOCRIS) dissolved in DMSO ...
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bioRxiv - Cancer Biology 2023Quote: ... Organoids are pelleted and gently resuspended in BTOM-ER containing 5% Matrigel and ROCK-inhibitor (10 μM Y267632, Tocris), and then plated on top of a solidified Matrigel-coated well ...
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bioRxiv - Cell Biology 2023Quote: For inhibition of P2X4R cells were pre-incubated for 30 min with 10 μM of 5-BDBD (Tocris Bioscience). Blockage of αvβ3/αvβ5 integrins was achieved by the pre-incubation with 10 μM of cilengitide for 2 hours (Sigma-Aldrich).
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bioRxiv - Neuroscience 2023Quote: ... anisomycin and N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (AM-251) were purchased from Tocris Bioscience ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... the α4-selective nAChR antagonist dihydro-β-erythroidine hydrobromide (DHβE; 5 mg/kg in sterile saline; Tocris, Bristol, UK), or the α7-selective nAChR antagonist methyllycaconitine citrate (MLA ...
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bioRxiv - Neuroscience 2024Quote: ... All mice were given a 250μl subcutaneous injection of bromocriptine (5mg/kg, 5% ethanol/saline; Tocris Bioscience Cat#0427) prior to being mated ...
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bioRxiv - Neuroscience 2024Quote: ... CACNA1A+/− networks on MEA at DIV51 were treated with 20 µM 4-aminopyridine (4-AP; Tocris, #504-24-5) and recorded for 30 minutes after the compound was added ...
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bioRxiv - Neuroscience 2024Quote: ... Immunoblot was obtained by first blocking membranes for 1 h at room temperature with a solution of 0.1% Tween 20 and 5% Bovine Serum Albumin (BSA) (#5217, Tocris) in 1× PBS (pH 7.4 ...
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bioRxiv - Cell Biology 2022Quote: ... Apoptosis was induced in non-primed macrophages using the Bcl-2 inhibitor venetoclax (ABT-199, Tocris 6960) at 25 μM for 16 h ...
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bioRxiv - Neuroscience 2021Quote: ... IP3 receptors were blocked by bath application of 2-APB (100 µM, Tocris, Germany, micro-perfusion pump), 2-APB was applied at least 15 min prior t-LTP induction and was present throughout the recordings ...
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bioRxiv - Cancer Biology 2019Quote: ... ADORA2b selective antagonist 4-(2,3,6,7-Tetrahydro-2, 6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid (PSB1115) (Tocris) (Lin et al. ...
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bioRxiv - Cell Biology 2021Quote: 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride (NE-100 hydrochloride) was purchased from Tocris (3133). Stock and work solutions were prepared using 100% dimethyl sulfoxide sterile-filtered (DMSO ...
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bioRxiv - Genomics 2022Quote: ... Media was then changed to CM Media supplemented with 2 μM Wnt-C59 (Tocris Biosciences, Bristol, UK) for 2 days prior to switching to CM Media without any supplements ...
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bioRxiv - Developmental Biology 2021Quote: ... early somite (1 day; 2 µM SB505124, 4 µM dorsomorphin, 500 nM PD173074 [cat. num. 3044; Tocris Bioscience ...