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Citations for Tocris :
601 - 643 of 643 citations for N6 2 aminoethyl 9H purine 2 6 diamine since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Physiology 2023Quote: ... animals either received vehicle (1 µl DMSO; n = 6) or the DREADD ligand clozapine n-oxide (CNO, Tocris; 0.1 mg/µl DMSO ...
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bioRxiv - Neuroscience 2024Quote: ... 5 μM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt (NBQX, AMPA receptor antagonist, Tocris, 1044) and 5 μM (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP ...
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bioRxiv - Neuroscience 2021Quote: ... The resulting cell pellet was broken up and resuspended in 1ml E8 media by 1000ul pipette and distributed on a Geltrex coated 6 well plate with E8 and 10µM ROCK inhibitor (Y-27632 dihydrochloride, Tocris) for 24 hours ...
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bioRxiv - Neuroscience 2020Quote: ... and re-plated at 1:6 ratio on Matrigel-coated plate in neural medium supplemented with 1μM CHIR99021 (Tocris), 2μM DMH1 (Tocris) ...
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bioRxiv - Neuroscience 2020Quote: ... and re-plated at 1:6 ratio on Matrigel-coated plate in neural medium supplemented with 3μM CHIR99021 (Tocris), 2μM DMH1 (Tocris) ...
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bioRxiv - Cell Biology 2021Quote: ... or the AMPA-iGluR specific inhibitor 2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline (NBQX, cat. num. 373, Tocris). Drugs were dissolved in ESC complete media (no 2i ...
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bioRxiv - Neuroscience 2022Quote: ... were recorded during the application of the competitive AMPA/kainate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX; 20 μM, Tocris) and the selective NMDA receptor antagonist amino-5-phosphonopentanoic acid (AP5 ...
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bioRxiv - Neuroscience 2022Quote: ... drugs were bath applied at the following concentrations (in μM): 10 6-Cyano-7-nitroquinoxaline-2,3-dione disodium salt (CNQX, Tocris), 50 D-2-amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Cell Biology 2024Quote: ... Cultures were passaged every 6 days and kept in a cycle of 3 days in 5μM ROCK inhibitor (Y-27632 dihydrochloride; Tocris), 3 days in the absence of rock inhibitor ...
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Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortexbioRxiv - Neuroscience 2023Quote: ... were recorded at −70mV in presence of 20□μM CNQX (6-Cyano-7-nitroquinoxaline-2,3-dione disodium, an AMPA receptor antagonist, Tocris) and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid ...
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bioRxiv - Molecular Biology 2022Quote: ... 6 replicates of each condition were treated with DMSO or 100 nM dTAG13 (Tocris Bioscience, Fisher Scientific 66-055) for 2 hours ...
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bioRxiv - Neuroscience 2023Quote: ... slices were incubated in recording ACSF supplemented with 5 μM 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX, Tocris, 1045) and 100 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Cell Biology 2022Quote: ... Neuroectoderm was induced for 6 days in CDM-BSA supplemented with 12ng/ml FGF2 and 10μM SB431542 (Activin/Nodal/TGFβ inhibitor; Tocris), as previously described34 ...
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bioRxiv - Immunology 2023Quote: Co-culture assays: thymocytes were isolated from untreated C57BL/6 mice and incubated with Nigericin (10 µM, Tocris, 4312) and LPS (1 ng/ml ...
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bioRxiv - Cell Biology 2024Quote: ... transgenic embryos were treated in 6-well plates at the indicated time points with 5 μM Ro5-3335 (Tocris) or DMSO (Sigma ...
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bioRxiv - Neuroscience 2024Quote: ... were recorded at −70mV in presence of 10□μM CNQX (6-Cyano-7-nitroquinoxaline-2,3-dione disodium, an AMPA receptor antagonist, Tocris) and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid ...
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bioRxiv - Animal Behavior and Cognition 2024Quote: The 5HT2B antagonist 6-Chloro-2,3-dihydro-5-methyl-N-5-quinolinyl-1H-indole-1-carboxamide (SB215505; Tocris Bioscience) at a dose of 1.0 mg/kg.
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bioRxiv - Developmental Biology 2024Quote: ... Monolayers followed the same timing but were cultured in 6-well plates in 3.5 ml of medium and 5 µM XAV939 (Tocris) was included between day 3 and 6.
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bioRxiv - Developmental Biology 2021Quote: ... coated 12-well plates at the density of 6×105 cells/well in mTeSR1 medium supplemented with 10 μM ROCK inhibitor (Y-27632, Tocris). The medium was changed daily ...
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bioRxiv - Neuroscience 2021Quote: ... C57BL/6 wild-type mice were daily treated with vehicle or clemastine (#1453 Tocris; 50mg/kg solved in 10% DMSO) by intraperitoneal injections from postnatal day 5 (P5 ...
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bioRxiv - Molecular Biology 2020Quote: ... kin28as strains and their controls were then grown to an OD600 of 0.8 and treated with 6 μM of 1-Naphthyl PP1 (NAPP1; Tocris Bioscience) for 15 min ...
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bioRxiv - Neuroscience 2021Quote: ... 10 μM NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline) and 50 μM AP-5 (Tocris Bioscience, UK) were applied in the bath to block excitatory synaptic responses.
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bioRxiv - Neuroscience 2023Quote: ... Neuronal activity was manipulated either with field stimulation (100mA,10 Hz,600 AP) or 6 hours of 50 µM picrotoxin (PTX, Tocris) treatment 65 ...
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bioRxiv - Molecular Biology 2023Quote: ... Male Sprague Dawley (SD) rats (6-10 weeks old) were administered with a single dose of Sugen 5416 (SU) (20mg/kg, Tocris) delivered in CMC vehicle (as previously described)16 or DMSO and placed in hypoxia chambers (10% O2 ...
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bioRxiv - Neuroscience 2022Quote: Primary microglia cells from C57Bl/6 J mice cultured in presence of CSF-1 were treated with Formoterol (10 ng/ml, cat # 1448, Tocris) or vehicle for 1 hour ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 μM 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531; GABAA receptor antagonist, all from Tocris). The resting membrane potential was measured after whole-cell configuration was achieved ...
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bioRxiv - Cancer Biology 2024Quote: Around 1 x 105 cells were seeded in a 6-well plate for the drug treatment with Brequinar (Tocris, 6196) in a dose-dependent manner for 72 h ...
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bioRxiv - Biochemistry 2024Quote: ... A549 RIG-I−/− ACE2+ cells (80-90% confluent in 6-well plates) were transduced by adding 10 µg ml−1 Polybrene (Tocris) and recombinant lentivirus to a multiplicity of infection (MOI ...
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Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s diseasebioRxiv - Neuroscience 2020Quote: ... Cells were dissociated into a single-cell suspension using accutase and seeded at a density of 1.0 x 106 cells per well on Matrigel coated 6-well plates in mTeSR1 supplemented with 10 mM ROCK inhibitor Y-27632 (Tocris, 1254).
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bioRxiv - Neuroscience 2022Quote: ... and singularized cells were seeded at a defined density (between 42,000 and 62,000 cells/cm2 depending on the hiPSC line) on matrigel coated 6-well plates in StemMACS iPS-Brew supplemented with 10 µM Y27632 (ROCK inhibitor, Tocris Bioscience). After 24 h (Fig ...
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bioRxiv - Cell Biology 2020Quote: ... hESCs were induced with chemically defined medium (CDM3, containing RPMI/1640, AA and BSA) as the basal medium [30] containing 6 μM CHIR99021 (Tocris Bioscience) from day 0 to day 2 ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 µM 6-imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531;GABAA receptor antagonist; all from Tocris Bioscience).
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bioRxiv - Neuroscience 2024Quote: ... to block voltage-gated sodium channels was applied or a mixture of 10 μM NBQX (2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline; Tocris Bioscience, #1044), 10 μM DL-AP4 (DL-2-amino-4-phosphonobutyric acid ...
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bioRxiv - Bioengineering 2024Quote: ... and plated at a minimum density of 1.5 x 105 cells/well of a Matrigel-coated 6-well plate in mTeSR™ with Y-27632 dihydrochloride (10µM, cat: 1254, Tocris Bioscience), which was removed from culture medium after 1 day ...
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bioRxiv - Cell Biology 2024Quote: ... One million cells were plated per well of a Geltrex-coated 6-well plate in E6 medium (Thermo A1516401) supplemented with 10 μM ROCK inhibitor Y-27632 (Tocris 1254).
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bioRxiv - Neuroscience 2020Quote: Adult (12-13 week old) male C57BL/6 mice received daily intraperitoneal (i.p.) injections of ADRβ3 agonist CL316,243 (Tocris Bioscience, Bristol, U.K.; Cat # 1499), at 1.0 mg/kg BW or an equivalent amount of sterile saline ...
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bioRxiv - Neuroscience 2022Quote: ... the medium was replaced with HBSS containing 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5′-triphosphate (ARL 67156; Tocris, 1283) at a concentration of 100 μM ...
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bioRxiv - Cell Biology 2023Quote: ... and distributed to 6-well low-attachment plates containing primitive streak/embryoid body media (10 μM Y-27632 (Tocris/Biotehne, Minneapolis, MN), 3 ng/ml BMP4 (R&D/Biotechne ...
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bioRxiv - Neuroscience 2022Quote: ... food was removed for 3 hours (3 pm – 6 pm) and mice received either vehicle or CCK-8s (20 μg/kg BW; i.p.; Tocris, St. Louis, USA) injection at dark onset (6 pm ...
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bioRxiv - Neuroscience 2021Quote: ... 3 or 6 μg/hemisphere of LY379268 (Cat No.: 2453, Batch No.: 9B/232416, CAS No.: 191471-52-0, Tocris Bioscience, Oakville, Ontario), in a counterbalanced ...
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bioRxiv - Neuroscience 2022Quote: ... dissociated hiPSCs were plated at 1×104 cells/cm2 into 6-well plates in the presence of 10 µM ROCK inhibitor (Y-27632, Tocris Bioscience, Bristol, UK). Cortical and hypothalamic differentiation took place on a substrate of geltrex (1:100 ...
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bioRxiv - Neuroscience 2024Quote: ... hiPSCs were plated in 6-well plates in Basal Neural Maintenance media (BNMM) (Suppl. Table 1) supplemented with 10 μM SB-431542 (Tocris, Bristol, United Kingdom) and 0.5 μM LDN-193189 (Tocris ...
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bioRxiv - Neuroscience 2023Quote: ... for 18-30 minutes and reseeding them into Matrigel (BD Bioscience #354277)-coated 6-well plates at 1 x 105 cells/cm2 in cortical differentiation medium containing 10 µM Rock-inhibitor (Tocris, Minneapolis, MN, USA #1254), which was removed after 24 hours ...