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Citations for Tocris :
601 - 650 of 720 citations for 6 Bromo benzo d isoxazole 3 carboxylic acid since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Pharmacology and Toxicology 2023Quote: ... 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy) phenyl]-2-pyridinyl]thio]-acetamide (BAY 60-6583; Tocris, 910487-58-0), 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide (2-Chloro-IB-MECA ...
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bioRxiv - Cancer Biology 2023Quote: Around 1 x 105 cells were seeded in a 6-well plate for the drug treatment with Brequinar (Tocris, 6196) in a dose-dependent manner for 72 h ...
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bioRxiv - Molecular Biology 2023Quote: ... Male Sprague Dawley (SD) rats (6-10 weeks old) were administered with a single dose of Sugen 5416 (SU) (20mg/kg, Tocris) delivered in CMC vehicle (as previously described)16 or DMSO and placed in hypoxia chambers (10% O2 ...
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bioRxiv - Neuroscience 2021Quote: ... NMDA receptor (R) dependency was tested by application of an NMDAR antagonist (APV 50 µM, DL-2-Amino-5-phosphonopentanoic acid, Tocris, Germany) in the bath solution ...
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bioRxiv - Neuroscience 2020Quote: ... to isolate inner retinal signaling (B-waves) and DL-2-Amino-4-phosphonobutyric acid (DL-AP4, 40µM, Tocris Bioscience, Bristol, U.K.) to isolate the photoreceptor component of the ERG signal (A-wave) ...
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bioRxiv - Neuroscience 2023Quote: ... one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich, A4403], 125 µM db-cAMP [Tocris, 1141] ...
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bioRxiv - Neuroscience 2023Quote: ... Mice were injected intraperitoneally (i.p.) with 5.0mg/kg synthetic kainic acid (KA) dissolved in 0.9% saline (#7065, Tocris Bioscience, Bristol, United Kingdom). At twenty-minute intervals ...
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bioRxiv - Neuroscience 2021Quote: Varenicline or 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h] [3]benzazepine tartrate (Tocris, UK) was dissolved in sterile 0.9% physiological saline for a final dose of 1 mg/kg free base ...
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bioRxiv - Neuroscience 2020Quote: ... medium was exchanged every 3-4 days with RGC induction media containing: DAPT (3uM, Tocris), 10μM Rock inhibitor (Y27632) ...
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bioRxiv - Neuroscience 2021Quote: ... some slices were incubated at 37°C with 3 µM puromycin (Tocris #40-895-0) at 65-75 minutes post-slicing ...
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bioRxiv - Neuroscience 2022Quote: ... with the addition of either 3 μM or 10 mM GABA (Tocris; Cat. No. 0344). Sylgard 184 (Dow Corning ...
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bioRxiv - Neuroscience 2021Quote: AM251 pharmacology: in experiments using the CB1 antagonist AM251 (3 µM) (Tocris and AdooQ biosciences), the drug (diluted in DMSO ...
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bioRxiv - Neuroscience 2020Quote: ... with either 3 mg/kg clozapine N-oxide (CNO; Tocris, Catalog: 4936, Lot: 13D/233085) in 0.5% DMSO and saline ...
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bioRxiv - Neuroscience 2022Quote: ... mEPSCs were recorded in the presence of 3 μM AMPA receptor antagonist NBQX (Tocris Bioscience) in standard external solution.
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bioRxiv - Cancer Biology 2023Quote: ... N-(1,3,4-thiadiazol-2-yl) pyridine-3-carboxamide dihydrochloride (TGN-020, Tocris Cat No 5425) was used in vitro at 10-100 μM ...
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bioRxiv - Developmental Biology 2023Quote: ... N6,2’-O-Dibutyryladenosine 3’,5’-cyclic monophosphate sodium salt (DB-cAMP, TOCRIS Cat. No.: 1141), 8-(4-Chlorophenylthio)-N6-phenyladenosine-3’,5’-cyclic monophosphate sodium salt (8C6P-cAMP ...
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bioRxiv - Cell Biology 2023Quote: ... the CDBM medium was supplemented with 0.6 U/ml heparin and 3 mM IWP2 (Tocris) for another 3-day incubation with medium refreshed daily ...
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bioRxiv - Bioengineering 2021Quote: ... supplemented with FGF-2 (20 ng ml−1), Activin-A (50 ng ml−1), BMP-4 (10 ng ml−1, R&D) and LY294002 (10 mM Tocris). Media was changed again after 42 hours to CDM-BSA supplemented with FGF-2 (8 ng ml−1) ...
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bioRxiv - Neuroscience 2021Quote: ... Drug-evoked locomotor-like activities were induced by bath-applying 10 to 14 µM of N-methyl- D-aspartate (NMDA, Tocris) and serotonin (5-HT ...
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bioRxiv - Neuroscience 2020Quote: ... Intrinsic properties were recorded in the presence of 10 μM biccuculine methiodide (Enzo, Life Sciences) and 10 μM saclofen (R&D, Tocris). We studied only cells with series resistance < 25 MΩ ...
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bioRxiv - Developmental Biology 2020Quote: ... day 3 NMP-like cultures were treated with Accutase and replated at a density of 45,000 cells/cm2 on Geltrex-coated plates in N2B27 containing FGF2 (40 ng/ml, R&D) and CHIR99021 (8 µM, Tocris) for two days ...
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bioRxiv - Neuroscience 2020Quote: ... N-methyl D-aspartate (NMDA) receptors were blocked by the non-competitive NMDA receptor antagonist MK-801 (Tocris; 100 μM), co-applied with the competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid AMPA/kainate receptor antagonist CNQX (Tocris ...
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bioRxiv - Cell Biology 2021Quote: ... The growth medium was supplemented with 100 ng/mL human recombinant epidermal growth factor (EGF) (R&D) as the major growth-supporting peptide and was further supplemented with 10 µM Y27632 (Tocris), 500 nM A83-01 (Tocris) ...
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bioRxiv - Microbiology 2022Quote: ... 3 μl of 10 mM of NBD-(linezolid-7-nitrobenz-2-oxa-1,3-diazol-4-yl)-amino-D-alanine (NADA) (Tocris Bioscience) was added to the resuspension ...
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bioRxiv - Cancer Biology 2022Quote: ... and plated at 60,000 cells/cm2 in N2B27 medium supplemented with 20 ng/ml of FGF2 (Cat# 233-FB/CF, R&D) and 4 μM of CHIR 99021 (Cat# 4423, Tocris) and 10 μM of Rock Inhibitor (Y-27632 ...
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bioRxiv - Cell Biology 2023Quote: ... The indicated drugs were directly added in the culture medium: torin-1 (10 μM) (4247/10, R&D and Tocris), Rotenone (500 nM ...
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bioRxiv - Immunology 2020Quote: ... These cells were then directed to become proepicardial cells by the addition of retinoic acid and WNT CHIR 99021 followed by TGFβ inhibition (SB431542, Tocris Bioscience 1614). Finally ...
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bioRxiv - Neuroscience 2023Quote: ... and cells were centrifuged at 200 rcf for 5 min and resuspended in N2B27 with the same supplements as on day 0 except for the removal of Y27632 and addition of all-trans retinoic acid (100 nM; Tocris, 0695/50) and SAG (500 nM ...
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Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s diseasebioRxiv - Neuroscience 2020Quote: ... Cells were dissociated into a single-cell suspension using accutase and seeded at a density of 1.0 x 106 cells per well on Matrigel coated 6-well plates in mTeSR1 supplemented with 10 mM ROCK inhibitor Y-27632 (Tocris, 1254).
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bioRxiv - Neuroscience 2022Quote: ... and singularized cells were seeded at a defined density (between 42,000 and 62,000 cells/cm2 depending on the hiPSC line) on matrigel coated 6-well plates in StemMACS iPS-Brew supplemented with 10 µM Y27632 (ROCK inhibitor, Tocris Bioscience). After 24 h (Fig ...
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bioRxiv - Cell Biology 2020Quote: ... hESCs were induced with chemically defined medium (CDM3, containing RPMI/1640, AA and BSA) as the basal medium [30] containing 6 μM CHIR99021 (Tocris Bioscience) from day 0 to day 2 ...
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bioRxiv - Developmental Biology 2021Quote: ... From passage 3 cells were grown NMP differentiation medium supplemented with 5 μM Y-27632 (Tocris). Human iPSCs were found to detach more readily than hESCs ...
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bioRxiv - Developmental Biology 2020Quote: ... short-term serum-free culture was carried out in N2B27 supplemented with 3 μM CHIR99201 (Tocris), 1 μg/ml of Heparin (Sigma ...
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bioRxiv - Developmental Biology 2020Quote: ... mTeSR Plus was replaced with the N2B27 basal medium supplemented with 3 μM CHIR99021 (Tocris Bioscience) and 40 ng/ml basic fibroblast growth factor bFGF/FGF2 (R&D Systems) ...
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bioRxiv - Neuroscience 2020Quote: ... each disk with neurons was transferred into the physiological saline solution containing NBQX (3 μM, Tocris) and bicuculine (30 μM ...
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Safety and efficacy of C9ORF72-repeat RNA nuclear export inhibition in amyotrophic lateral sclerosisbioRxiv - Systems Biology 2021Quote: ... supplemented with SMAD inhibitors (DMH-1 2 µM; SB431542-10 µM and CHIR99021 3 µM [ [Tocris]). The medium was changed every day for 6 days ...
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bioRxiv - Neuroscience 2020Quote: ... Readings were taken before and 3–4 min after application of 20 μM 2-AG (Tocris) to activate CB1R or the eCB sensor.
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bioRxiv - Neuroscience 2021Quote: ... 3-((±)2-carboxypiperazin-4yl) propyl-1-phosphate (CPP, NMDA receptor antagonist, 20 μM; Tocris Bioscience, UK) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Bioengineering 2021Quote: ... Plates were centrifuged at 100xg for 3 minutes in E8 medium containing 10 μM Y27632 (Tocris). The following day ...
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bioRxiv - Neuroscience 2023Quote: ... KA (3 mg/mL) was prepared on the day of experimentation by dissolving KA (Tocris, 0222) in a 0.9% bacteriostatic saline solution ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Physiology 2021Quote: ... Picrotoxin (100 µM) was used to block GABAA-receptor-mediated currents and D-2-amino-5-phosphonovalerate (APV; 20 µMm, Tocris Bioscience), and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Cell Biology 2021Quote: ... 4 × 106 cells were seeded in a 21 cm2 dish and after 24 hours stimulated for ten minutes with 10 μM DAMGO ([D-Ala2, N-MePhe4, Gly-ol]-enkephalin, Tocris 1171) in DMEM medium (Sigma-Aldrich ...
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Neuroscience 2023Quote: ... all buffers and solutions used during the process (from animal perfusion to sorted cells flash freezing) were supplemented with a cocktail composed of Actinomycin D (3μM, Tocris #1229/10), Anisomycin (100 μM ...
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bioRxiv - Neuroscience 2021Quote: ... and MNI-caged-L-glutamate ((S)-α-amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid) were purchased from Tocris (Bristol, UK). Rhod-2 tripotassium salt was purchased from AAT Bioquest (Sunnyvale ...
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bioRxiv - Neuroscience 2020Quote: Adult (12-13 week old) male C57BL/6 mice received daily intraperitoneal (i.p.) injections of ADRβ3 agonist CL316,243 (Tocris Bioscience, Bristol, U.K.; Cat # 1499), at 1.0 mg/kg BW or an equivalent amount of sterile saline ...
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bioRxiv - Cell Biology 2021Quote: ... Calcium-like peptide 2 (CALP2) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride (W-7) were obtained from Tocris (Minneapolis, MN). CaM kinase II and calcineurin inhibitors ...
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bioRxiv - Cell Biology 2023Quote: ... and distributed to 6-well low-attachment plates containing primitive streak/embryoid body media (10 μM Y-27632 (Tocris/Biotehne, Minneapolis, MN), 3 ng/ml BMP4 (R&D/Biotechne ...
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bioRxiv - Neuroscience 2021Quote: ... free microdialysis probes (n=3) were inserted into a solution of 100nM adenosine (Tocris Biosciences, Bristol, U.K.) in Ringer’s Solution ...