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Citations for Tocris :
551 - 600 of 693 citations for 8 Fluoro quinazoline 2 4 diamine since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesisbioRxiv - Cell Biology 2023Quote: ... the medium was replaced with differentiation medium containing 5 μM IWP-2 (TOCRIS, Cat.# 3533), a Wnt inhibitor ...
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bioRxiv - Neuroscience 2024Quote: ... VU0360172 [N-cyclobutyl-6-(2-(3-fluorophenyl)ethynyl) pyridine-3-carboxamide] was purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2024Quote: ... USA) and superfused with ACSF containing 2 mM CaCl2 and 20 µM bicuculline methiodide (Tocris) at a rate of 3 – 4 ml/min at RT ...
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bioRxiv - Bioengineering 2021Quote: ... supplemented with FGF-2 (20 ng ml−1), Activin-A (50 ng ml−1), BMP-4 (10 ng ml−1, R&D) and LY294002 (10 mM Tocris). Media was changed again after 42 hours to CDM-BSA supplemented with FGF-2 (8 ng ml−1) ...
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bioRxiv - Neuroscience 2020Quote: ... 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide) and antagonist WRW4 (Trp-Arg-Trp-Trp-Trp-Trp-NH2) were purchased from Tocris Ltd ...
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bioRxiv - Cell Biology 2021Quote: ... flow cytometer, and the fractions of stained cells were quantified using FloJo 10.6, with Staurosporine (4 h, 5 μM) (Tocris, 1285) used as a positive control for cell death and to help establish gating of the sorted cells.
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bioRxiv - Neuroscience 2021Quote: Structural plasticity of dendritic spines was stimulated through uncaging of 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris) using a Ti ...
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bioRxiv - Neuroscience 2019Quote: ... (+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC 80) (20mg/kg; Tocris) dissolved in 1mM HCl in saline.
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bioRxiv - Developmental Biology 2021Quote: ... Neural progenitors were briefly washed (with DMEM/F12) and were then treated with CDM2 basal media supplemented with CHIR99021 (4 μM; Tocris), SB-505124 (2 μM ...
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bioRxiv - Neuroscience 2022Quote: ... we used a cocktail of the mGluR-4 antagonist [0.5 mM MSOP: (RS)-α-methylserine-O-phosphate obtained from Tocris Biosciences] with either umami at 300 mM or MSGa at 600 mM ...
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bioRxiv - Cancer Biology 2022Quote: ... and plated at 60,000 cells/cm2 in N2B27 medium supplemented with 20 ng/ml of FGF2 (Cat# 233-FB/CF, R&D) and 4 μM of CHIR 99021 (Cat# 4423, Tocris) and 10 μM of Rock Inhibitor (Y-27632 ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 μM 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531; GABAA receptor antagonist, all from Tocris). The resting membrane potential was measured after whole-cell configuration was achieved ...
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bioRxiv - Neuroscience 2023Quote: ... was set to 720 nm and used to uncage 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris). Up to four spines in separate regions of interest (ROI ...
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bioRxiv - Neuroscience 2023Quote: ... Cells were then rinsed with 3x with PBS before fixation with 4% paraformaldehyde in PBS with 10 μg/ml Hoechest 33342 (Tocris) for 30 min at RT ...
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Safety and efficacy of C9ORF72-repeat RNA nuclear export inhibition in amyotrophic lateral sclerosisbioRxiv - Systems Biology 2021Quote: ... supplemented with SMAD inhibitors (DMH-1 2 µM; SB431542-10 µM and CHIR99021 3 µM [ [Tocris]). The medium was changed every day for 6 days ...
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bioRxiv - Neuroscience 2020Quote: ... JNJ16259685 and 2-Methyl-6-(phenylethynyl)pyridine (MPEP) hydrochloride were purchased from Tocris (Minneapolis MN, USA). (±)-Sulpiride was purchased from MilliporeSigma ...
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bioRxiv - Neuroscience 2020Quote: ... WIN 55,212-2 (WIN, 0.5 µg/0.5-µL infusion/hemisphere; n = 11; Tocris Bioscience, Minneapolis, MN) or VEH (10% DMSO ...
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bioRxiv - Cancer Biology 2022Quote: ... One hour before dsDNA transfection cells were pre-treated with 2 µM NU7441 (#3712, Biotechne/Tocris) in OptiMEM and were subsequently transfected with dsDNA (1 µg/ml) ...
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bioRxiv - Neuroscience 2021Quote: ... 3-((±)2-carboxypiperazin-4yl) propyl-1-phosphate (CPP, NMDA receptor antagonist, 20 μM; Tocris Bioscience, UK) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Cancer Biology 2022Quote: ... 2% Sodium deoxycholate and 0.2% SDS including protease inhibitors (Aprotinin (TOCRIS Bioscience Cat. no. 4139/10) Leupeptin (Fisher Scientific ...
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bioRxiv - Genomics 2019Quote: ... the previously described medium was replaced with heart medium containing 2 μM Wnt-C59 (Tocris, 5148). On days 5 ...
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bioRxiv - Neuroscience 2020Quote: NNC-711 (1,2,5,6-Tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-3-pyridinecarboxylic acid hydrochloride) from Tocris
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bioRxiv - Developmental Biology 2021Quote: ... Lin- c-Kit+ cells were sorted into 2%FCS-PBS with 100µM IWR-1 (Tocris, 3532) or control vehicle ...
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bioRxiv - Microbiology 2020Quote: ... cells were pretreated for 3h before infection with Tautomycetin (0.8 μM, Tocris Bioscience, 119757-73-2) or Okadaic acid (0.1 μM ...
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bioRxiv - Molecular Biology 2021Quote: Cells were treated for 2 hrs with vehicle (DMSO) or with 250 nM Torin1 (Tocris Biosciences), or for 1 hr with 50 μM Ly29004 (Tocris Biosciences ...
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bioRxiv - Neuroscience 2022Quote: ... we slowly infused 200 nl of the GABAA receptor agonist muscimol (Tocris; 2 μM in saline) into the target area using a micro-syringe pump (KD Scientific ...
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bioRxiv - Neuroscience 2022Quote: The β3AR-selective antagonist SR59230A (2 mg/kg/day or 10 mg/kg/day; Tocris Bioscience) or vehicle (2:3 ratio of DMSO:0.9% saline ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Biochemistry 2023Quote: ... Cannabinoid ligands (anandamide [AEA], 2-arachydonyl-glycerol [2AG], SR144528, HU210, HU308, cannabinol) were obtained from Tocris Bioscience and dissolved in DMSO to a storage concentration of 10 mM ...
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bioRxiv - Developmental Biology 2023Quote: ... at a density of 2 × 103 cells/cm2 with 10µM ROCK inhibitor (Y-27632; Tocris, 1254) added in culture medium for 1 day after hESCs passaging ...
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bioRxiv - Cell Biology 2024Quote: ... the WNT signaling inhibitor IWP-2 (2μM in DMSO, day 21-42, Tocris Bioscience, Bristol, UK), the hedgehog inhibitor cyclopamine (10μM in DMSO ...
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bioRxiv - Developmental Biology 2024Quote: ... Cells were treated as control or with 2 µM DDR1 inhibitor DDR1-in-1 (Tocris 5077) or 5 µM RUNX1 inhibitor AI-10-104 (Aobious AOB17076) ...
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bioRxiv - Neuroscience 2022Quote: ... 12-well plates at 3-4 × 105 cells/well in mTeSR1 with 10 µM rho-kinase inhibitor (Y-27632; Tocris, 1254). Medium without the inhibitor was replaced daily until the cells reach 80-100% confluency ...
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bioRxiv - Neuroscience 2021Quote: ... Alexa-fluorophore conjugated secondary antibodies were added in blocking solution for 1 hour at 4°C followed by treatment with Methoxy-X04 (Tocris, 4920) for 15 minutes at room temperature to label amyloid-beta plaques ...
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bioRxiv - Neuroscience 2020Quote: ... ACSF of similar composition to the normal ACSF but with increased concentration (4 mM) of MgCl2 and CaCl2 and supplemented with 100μM MNI-caged glutamate (Tocris Bioscience, UK) for glutamate uncaging experiments ...
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bioRxiv - Neuroscience 2022Quote: ... where they were immobilized under a nylon mesh (Smart Ephys, SHD-26GH/10) and paralyzed by injecting 0.5 nL of bungarotoxin at 0.5 mM (Tocris, #110.32-79-4) in the trunk musculature ...
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Biochemistry 2022Quote: ... Positive clones were analyzed by Sanger sequencing with primers #3 and #4 (Integrated DNA Technologies, Supplementary Table S5) and degradation upon dTAG-13 (Tocris, 6605) treatment was confirmed by Western Blot by a-Chaf1a antibody (65) ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 µM 6-imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531;GABAA receptor antagonist; all from Tocris Bioscience).
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bioRxiv - Neuroscience 2023Quote: ... the α7 nAChR specific agonist PNU 282987 (1.6 μg total dose; 0.2 μL volume of 4 μg/μL per side; PNU 282987, Tocris, Ellisville, MO, USA), or vehicle (artificial cerebrospinal fluid [aCSF] or 50/50% aCSF/dimethylsulfoxide [DMSO] ...
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bioRxiv - Neuroscience 2023Quote: ... Firing rates of individual channels were compared before and after treatment with potassium channel blocker 4-AP (50 μM; Tocris, 0940), sodium channel blocker TTX (1 μM ...
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bioRxiv - Cell Biology 2022Quote: ... Apoptosis was induced in non-primed macrophages using the Bcl-2 inhibitor venetoclax (ABT-199, Tocris 6960) at 25 μM for 16 h ...
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bioRxiv - Neuroscience 2021Quote: ... IP3 receptors were blocked by bath application of 2-APB (100 µM, Tocris, Germany, micro-perfusion pump), 2-APB was applied at least 15 min prior t-LTP induction and was present throughout the recordings ...
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bioRxiv - Genomics 2022Quote: ... Media was then changed to CM Media supplemented with 2 μM Wnt-C59 (Tocris Biosciences, Bristol, UK) for 2 days prior to switching to CM Media without any supplements ...
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bioRxiv - Neuroscience 2023Quote: ... in the presence of the mGluR5 antagonist 2-methyl-6 (phenylethynyl)-pyridine (MPEP, 25 μM; Tocris Bioscience) in ACSF at 31-33°C as previously (18) ...
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Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortexbioRxiv - Neuroscience 2023Quote: ... and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid, a selective NMDA receptor antagonist, Tocris).
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bioRxiv - Neuroscience 2020Quote: ... co-applied with the competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid AMPA/kainate receptor antagonist CNQX (Tocris; 20 μM) (n=13) ...
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bioRxiv - Neuroscience 2019Quote: ... (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid (TFB-TBOA) was purchased from Tocris (Minneapolis, MN; Cat# 2532). All other chemicals were purchased from MilliporeSigma (Burlington ...
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bioRxiv - Neuroscience 2023Quote: ... Drug treatments correspond to a single dose of cocaine hydrochloride at 20 mg/kg (Medisca, cat# 53-21-4, Canada) or D-amphetamine sulfate at 5 mg/kg (Tocris, 2813, UK) at doses known to increase locomotion87 ...
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bioRxiv - Neuroscience 2023Quote: ... was selected by qualifying the presence of innervated cancer spheroids at various heights within the gel layer before stimulation with either 4 µM Bradykinin (Tocris/Biotechne, #3004) or 1 µM Capsaicin (Tocris/Biotechne ...