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501 - 550 of 1791 citations for 2 1 ethylpentyl 1 3 dioxan 5 yl laurate since 2020

• Axo-vascular coupling mediated by oligodendrocytes

  Alejandro Restrepo, et al., bioRxiv - Neuroscience 2022

  Quote: ... L-161,982 (1 µM – Tocris, 2514), Indomethacin (25 µM – Tocris ...
• The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

  Tuba Barut, et al., bioRxiv - Microbiology 2022

  Quote: ... 1 μM A-83-01 (Tocris), 3 μM isoproterenol (abcam) ...
• A dedicated hypothalamic oxytocin circuit controls aversive social learning

  Takuya Osakada, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1 mg/kg Agonist2127 (Tocris, #5548) in saline was administered intraperitoneally ...
• Ketamine’s rapid antidepressant effects are mediated by Ca²⁺-permeable AMPA receptors in the hippocampus

  Anastasiya Zaytseva, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 μM (-)-Bicuculline methochloride (Tocris, 0131) and incubated in glycine buffer (Mg2+ free buffer with 0.2 mM glycine ...
• Lethal giant larvae gene family (Llgl1 and Llgl2) functions as a tumor suppressor in mouse skin epidermis

  Victor M. Bii, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1 μM prostaglandin E2 (Tocris, 2296), 10 mM Nicotinamide ...
• A Resource of Gene Expression Data from a Multiethnic Population Cohort of Induced Pluripotent Cell–Derived Cardiomyocytes

  Wenjian Lv, et al., bioRxiv - Genomics 2023

  Quote: ... and CHIR 99021 (1 nM, Tocris) for 2 days ...
• A human in vitro neuronal model for studying homeostatic plasticity at the network level

  Xiuming Yuan, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 μM tetrodotoxin (TTX, Tocris, 1069) was added to certain wells ...
• Lateral entorhinal cortex afferents reconfigure the activity in piriform cortex circuits

  Olivia Pedroncini, et al., bioRxiv - Neuroscience 2024

  Quote: ... When tetrodotoxin (TTX, 1 μM, Tocris) and 4-aminopyridine (4-AP ...
• FAST-STEM: A Human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices

  Aaron H. Rosenstein, et al., bioRxiv - Bioengineering 2024

  Quote: ... 1 – 1.5 μM CHIR99021 (Tocris Bioscience), and 5 ng/mL rhbFGF (R&D Systems) ...
• OrgaMeas: A pipeline that integrates all the processes of organelle image analysis

  Taiki Baba, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mdivi-1 was purchased from Tocris Bioscience (Bristol ...
• RBM39 shapes innate immunity through transcriptional and splicing control of key factors of the interferon response

  Teng-Feng Li, et al., bioRxiv - Immunology 2024

  Quote: ... 1 μM A83-01 (Tocris, UK). Cells ...
• Disentangling cell-intrinsic and extrinsic factors underlying gene expression evolution

  Alexander L. Starr, et al., bioRxiv - Evolutionary Biology 2024

  Quote: ... 1 µM MEK inhibitor PD0325901 (Tocris, Barton Ln ...
• A multiplexed, single-cell sequencing screen identifies compounds that increase neurogenic reprogramming of murine Muller glia

  Amy Tresenrider, et al., bioRxiv - Neuroscience 2024

  Quote: ... + drug or TSA (Tocris #1406/1) +drug ...
• Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing

  Jennifer L. Reedy, et al., bioRxiv - Immunology 2024

  Quote: ... 1 μM A-83-01 (Tocris), 0.2 μM DMH-1(Selleck Chemicals) ...
• A molecular switch for stress-induced activation of retrograde mitochondrial transport

  Christina Gladkova, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and 1 μM Thiamet G (Tocris), centrifuged at 200xg ...
• Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

  A. I. Ardisasmita, et al., bioRxiv - Cell Biology 2024

  Quote: ... 10 nM Gastrin (Tocris, 3006/1), 50 ng/ml EGF (Peprotech ...
• Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids

  Benjamin D. Umans, Yoav Gilad, bioRxiv - Genomics 2024

  Quote: ... and TTX (1 µM, Tocris 1069) and organoids were rapidly sheared with a pair of needles ...
• Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s Disease

  Rikesh M. Rajani, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1 mM L-glutamine (Gibco)] supplemented with 1 µM Dorsomorphin (Tocris) and 10 µM SB-431542 (Generon ...
• Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release

  Xuehan Zhou, et al., bioRxiv - Neuroscience 2024

  Quote: ... Or-phanin FQ (1-11) (Tocris); Leu-Enkephalin (Cayman) ...
• KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons

  Irune Guerra San Juan, et al., bioRxiv - Neuroscience 2024

  Quote: ... retinoic Acid (RA, 1 µM, Tocris) and smoothened agonist (SAG ...
• Integration of hunger and hormonal state gates infant-directed aggression

  Mingran Cao, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1 µl of ZD-7288 (Tocris #1000 ...
• Muscarinic receptor activation preferentially inhibits rebound in vulnerable dopaminergic neurons

  Megan L. Beaver, Rebekah C. Evans, bioRxiv - Neuroscience 2024

  Quote: ... 1 µM CGP-35348 (Tocris Bioscience), 5 µM NBQX (Tocris Bioscience) ...
• Cryopreservation of neuroectoderm on a pillar plate and in situ differentiation into human brain organoids

  Mona Zolfaghar, et al., bioRxiv - Bioengineering 2024

  Quote: ... 50 nM Chroman 1 (Tocris, 7163), and a polyamine supplement diluted at 1:1,000 (MilliporeSigma ...
• Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling

  Emily R. Feierman, et al., bioRxiv - Genetics 2024

  Quote: ... tetrodotoxin (TTX; 1 µM, Tocris 1069), D-2-amino-5-phosphonovalerate (D-AP5 ...
• TRPM4 is required for calcium oscillations downstream from the stretch-activated TRPV4 channel

  Oleg Yarishkin, et al., bioRxiv - Cell Biology 2021

  Quote: ... CBA (4-chloro-2-[[2-(2-chlorophenoxy) acetyl aminobenzoic acid from Tocris Bioscience (Minneapolis ...
• AMPA receptor anchoring at CA1 synapses is determined by an interplay of N-terminal domain and TARP γ8 interactions

  Jake F. Watson, et al., bioRxiv - Neuroscience 2020

  Quote: ... 2 μM 2-chloroadenosine (Tocris Cat#3136) was added to aCSF to dampen epileptiform activity ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Pelleted ESCs were resuspended in mTeSR1 + 1% penicillin/streptomycin + 1 μM of the ROCK inhibitor Thiazovivin (Tocris) (henceforth referred to “cell-plating media”) ...
• Mitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model

  Volha Liaudanskaya, et al., bioRxiv - Neuroscience 2022

  Quote: Dynamin-related protein 1 (Drp1) – mitochondria fission 1 protein (Fis1) peptide inhibitor P110 was purchased from Tocris Bioscience (cat ...
• Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure

  Jerome AJ Becker, et al., bioRxiv - Neuroscience 2020

  Quote: ... They were left drug-free for 3 weeks before chronic daily treatment with vehicle (NaCl 0.9%) or VU0155041 (Tocris, Bristol, UK; 2.5 or 5 mg/kg, i.p.) started ...
• A fluorescent sensor for spatiotemporally resolved endocannabinoid dynamics in vitro and in vivo

  Ao Dong, et al., bioRxiv - Neuroscience 2020

  Quote: ... 5-HT (Tocris), His (Tocris) ...
• Augmentation of extracellular ATP synergizes with chemotherapy in triple negative breast cancer

  Jasmine M Manouchehri, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 5-BDBD (Tocris), ENPP1 inhibitor C (Cayman Chemical ...
• A toolkit of highly selective and sensitive genetically encoded neuropeptide sensors

  Huan Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... 5 Desmopressin (Tocris), 1 NTS ...
• New and improved GRAB fluorescent sensors for monitoring dopaminergic activity in vivo

  Fangmiao Sun, et al., bioRxiv - Neuroscience 2020

  Quote: ... 5-HT (Tocris), histamine (Tocris) ...
• An ultrasensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... 5-HT (Tocris), HA (Tocris) ...
• Improved dual-color GRAB sensors for monitoring dopaminergic activity in vivo

  Yizhou Zhuo, et al., bioRxiv - Neuroscience 2023

  Quote: ... 5-HT (Tocris), HA (Tocris) ...
• The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer

  Jasmine M Manouchehri, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 5-BDBD (Tocris) and heparan sodium sulfate (Sigma).
• Single-cell mitochondrial variant enrichment resolved clonal tracking and spatial architecture in human embryonic hematopoiesis

  Yan Xue, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 mL of KSR medium and 1 μL of Y27632 (10 ug/ml) (Tocris, catalog no. 1254/10) were added ...
• Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis

  Igor Kondrychyn, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Dr-aqp8a.1 (Advanced Cell Diagnostics) using HRP-C3 and TSA Vivid Fluorophore 650 (Tocris, dilution 1:1500). Nuclei were counterstained with DAPI ready-to-use solution overnight at 40C ...
• Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis

  Igor Kondrychyn, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Dr-aqp1a.1 (Advanced Cell Diagnostics) using HRP-C1 and TSA Vivid Fluorophore 520 (Tocris, dilution 1:1500), and then C3 probe ...
• Sex-specific Effects of the Endocannabinoid Agonist 2-Arachidonoylglycerol on Sleep and Circadian Disruptions during Fentanyl Withdrawal

  Mackenzie C. Gamble, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2-Arachidonoylglycerol (2-AG) was obtained from Tocris Biosciences (Cat ...
• Single-cell profiling of transcriptome and histone modifications with EpiDamID

  Franka J. Rang, et al., bioRxiv - Genomics 2021

  Quote: ... 3 μM CHIR99021 (Tocris, SML1046-5MG), 1000 U/mL ESGRO mLIF ...
• 3D genome organization around nuclear speckles drives mRNA splicing efficiency

  Prashant Bhat, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 3 μM CHIR 99021 (Tocris, 4423), and 50 nM PI 103 (Tocris ...
• Defective Schwann cell lipid metabolism alters plasma membrane dynamics in Charcot-Marie-Tooth disease 1A

  Robert Prior, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 mM CHIR-99021 (Tocris Biosciences), and 20 µM SB 431542 (Tocris Biosciences) ...
• Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence

  Giovanni Pietrogrande, et al., bioRxiv - Neuroscience 2023

  Quote: ... and CHIR99021 3 μM (4423, Tocris). After 3 days ...
• Recording morphogen signals reveals origins of gastruloid symmetry breaking

  Harold M. McNamara, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 μM CHIR99021 (Tocris, 4423).
• Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

  Kizito-Tshitoko Tshilenge, et al., bioRxiv - Neuroscience 2022

  Quote: ... GABA (3 mM, Tocris Bioscience, 0344), CaCl2 (1.8 mM ...
• Identification of the main barriers to Ku accumulation in chromatin

  Madeleine Bossaert, et al., bioRxiv - Molecular Biology 2024

  Quote: ... or NU-7441 (3 µM, Tocris) were added when specified 1 h prior to irradiation ...
• Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway

  Artemis Koumoundourou, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 μM DCG-IV (Tocris Bioscience) was applied after each experiment ...
• Human neuron subtype programming through combinatorial patterning with scRNA-seq readouts

  Hsiu-Chuan Lin, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 3 µM CHIR99021 (Tocris Bioscience).
• Control of gastruloid patterning and morphogenesis by the Erk and Akt signaling pathways

  Evan J. Underhill, Jared E. Toettcher, bioRxiv - Developmental Biology 2023

  Quote: ... and 3 μM CHIR99021 (Tocris, 4423).