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Citations for Tocris :
501 - 550 of 1359 citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2020Quote: ... Cultures treated for 4 h with NMDA (50 μg/ml; Tocris #0114) and cultures incubated for 2 h with PI after fixation (referred to as ‘post-fixation’ ...
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bioRxiv - Cell Biology 2020Quote: ... 5 mg/kg BW for 2,3-bis(4-Hydroxyphenyl)-propionitrile (DPN, Tocris), or vehicle ...
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bioRxiv - Neuroscience 2022Quote: ... Cultures treated for 4 h with NMDA (50 μg/ml; #0114 Tocris) served as positive controls in these experiments ...
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bioRxiv - Bioengineering 2024Quote: ... CDM was supplemented with 4 μM CHIR99021 (Tocris Bioscience, cat. no. 4423), and from day 2 to day 4 ...
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bioRxiv - Genomics 2023Quote: ... 2,3-Bis(4-hydroxyphenyl)propionitrile (DPN, 5 mg/kg body weight, Tocris) and 4-(2-(3,5-dimethylisoxazol-4-yl)-1H-indol-3-yl)phenol (DIP ...
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bioRxiv - Neuroscience 2023Quote: ... we tested effects of an inhibitor (the spider toxin GsMTX 4; Tocris #4912 stock 50 μM in DMSO and the Piezo1 channel activator Yoda1 (Tocris 6586 10 and 20 uM ...
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bioRxiv - Developmental Biology 2021Quote: ... coated 12-well plates at the density of 6×105 cells/well in mTeSR1 medium supplemented with 10 μM ROCK inhibitor (Y-27632, Tocris). The medium was changed daily ...
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bioRxiv - Neuroscience 2021Quote: ... C57BL/6 wild-type mice were daily treated with vehicle or clemastine (#1453 Tocris; 50mg/kg solved in 10% DMSO) by intraperitoneal injections from postnatal day 5 (P5 ...
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bioRxiv - Neuroscience 2021Quote: ... 10 μM NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline) and 50 μM AP-5 (Tocris Bioscience, UK) were applied in the bath to block excitatory synaptic responses.
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bioRxiv - Molecular Biology 2023Quote: ... Male Sprague Dawley (SD) rats (6-10 weeks old) were administered with a single dose of Sugen 5416 (SU) (20mg/kg, Tocris) delivered in CMC vehicle (as previously described)16 or DMSO and placed in hypoxia chambers (10% O2 ...
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bioRxiv - Neuroscience 2023Quote: ... Neuronal activity was manipulated either with field stimulation (100mA,10 Hz,600 AP) or 6 hours of 50 µM picrotoxin (PTX, Tocris) treatment 65 ...
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bioRxiv - Neuroscience 2021Quote: Varenicline or 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h] [3]benzazepine tartrate (Tocris, UK) was dissolved in sterile 0.9% physiological saline for a final dose of 1 mg/kg free base ...
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bioRxiv - Neuroscience 2021Quote: ... some slices were incubated at 37°C with 3 µM puromycin (Tocris #40-895-0) at 65-75 minutes post-slicing ...
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bioRxiv - Neuroscience 2022Quote: ... with the addition of either 3 μM or 10 mM GABA (Tocris; Cat. No. 0344). Sylgard 184 (Dow Corning ...
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bioRxiv - Neuroscience 2021Quote: AM251 pharmacology: in experiments using the CB1 antagonist AM251 (3 µM) (Tocris and AdooQ biosciences), the drug (diluted in DMSO ...
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bioRxiv - Neuroscience 2020Quote: ... with either 3 mg/kg clozapine N-oxide (CNO; Tocris, Catalog: 4936, Lot: 13D/233085) in 0.5% DMSO and saline ...
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bioRxiv - Neuroscience 2022Quote: ... mEPSCs were recorded in the presence of 3 μM AMPA receptor antagonist NBQX (Tocris Bioscience) in standard external solution.
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bioRxiv - Developmental Biology 2023Quote: ... N6,2’-O-Dibutyryladenosine 3’,5’-cyclic monophosphate sodium salt (DB-cAMP, TOCRIS Cat. No.: 1141), 8-(4-Chlorophenylthio)-N6-phenyladenosine-3’,5’-cyclic monophosphate sodium salt (8C6P-cAMP ...
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bioRxiv - Cell Biology 2023Quote: ... the CDBM medium was supplemented with 0.6 U/ml heparin and 3 mM IWP2 (Tocris) for another 3-day incubation with medium refreshed daily ...
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bioRxiv - Molecular Biology 2024Quote: ... AML12 cells at 70% confluency were treated with 3 μM CHIR99021 (cat. no. 4423; Tocris) for 48h ...
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bioRxiv - Neuroscience 2024Quote: ... each animal underwent 3 consecutive trials before and after treatment with prazosin (7.5mg/kg, Tocris Biosciences ...
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bioRxiv - Cell Biology 2024Quote: ... 10 mM 3-methyladenine (3MA, diluted directly into cell culture medium at 10mM; Tocris, 3977), 2.5 µM brefeldin A (diluted from 25mM stock prepared in DMSO ...
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bioRxiv - Neuroscience 2021Quote: ... washed with 4-5 ml ice cold PBS supplemented with 0.5 % BSA (Tocris), and collected by centrifugation for 10 min (300 g) ...
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bioRxiv - Immunology 2021Quote: ... The non-selective MIF family cytokine inhibitor 4-IPP was obtained from Tocris Bioscience.
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bioRxiv - Bioengineering 2024Quote: ... supplemented with 50 ng/mL bone morphogenetic protein 4 (BMP4; Tocris; 314-BP) and 100 ng/mL activin A (Tocris ...
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bioRxiv - Cancer Biology 2023Quote: ... The N2/B27 medium was supplemented with 4 µM Dorsomorphin (Tocris, Cat # 3039) and 10 µM SB431542 (Tocris ...
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bioRxiv - Neuroscience 2023Quote: ... (S)-2-Amino-2-methyl-4-phosphonobutanoic acid (MAP4; 250 µM; Tocris, Item# 0711), Tetrodotoxin (TTX ...
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bioRxiv - Neuroscience 2023Quote: ... MNI-glutamate (4 methoxy-7-nitroindolinyl caged L-glutamate) was purchased from Tocris Bioscience ...
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bioRxiv - Neuroscience 2024Quote: ... to avoid polysynaptic recording and 10µM bicuculine (Tocris, CAS Number 485-49-4) by a 10 msec blue-light pulse at 0.1 Hz delivered through the 60X objective ...
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bioRxiv - Neuroscience 2024Quote: ... 10 μM DL-AP4 (DL-2-amino-4-phosphonobutyric acid, Tocris Bioscience, #0101), 10 μM (±)-CPP (3-[(R)-2-carboxypiperazin-4-yl]-propyl-1-phosphonic acid ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... 4-butoxy-N-(2,4-difluorophenyl)benzamide (VU0357121) was purchased from Tocris (Bristol, UK). [3H]methoxy-PEPy was custom synthesised by Pharmaron (Pharmaron ...
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bioRxiv - Cell Biology 2024Quote: ... cells were either treated with vehicle (media) or 100nM Ex-4 (Tocris, 1933). After glucose starvation and pretreatment ...
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Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s diseasebioRxiv - Neuroscience 2020Quote: ... Cells were dissociated into a single-cell suspension using accutase and seeded at a density of 1.0 x 106 cells per well on Matrigel coated 6-well plates in mTeSR1 supplemented with 10 mM ROCK inhibitor Y-27632 (Tocris, 1254).
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bioRxiv - Neuroscience 2022Quote: ... and singularized cells were seeded at a defined density (between 42,000 and 62,000 cells/cm2 depending on the hiPSC line) on matrigel coated 6-well plates in StemMACS iPS-Brew supplemented with 10 µM Y27632 (ROCK inhibitor, Tocris Bioscience). After 24 h (Fig ...
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bioRxiv - Cell Biology 2020Quote: ... hESCs were induced with chemically defined medium (CDM3, containing RPMI/1640, AA and BSA) as the basal medium [30] containing 6 μM CHIR99021 (Tocris Bioscience) from day 0 to day 2 ...
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bioRxiv - Neuroscience 2024Quote: ... to block voltage-gated sodium channels was applied or a mixture of 10 μM NBQX (2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline; Tocris Bioscience, #1044), 10 μM DL-AP4 (DL-2-amino-4-phosphonobutyric acid ...
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bioRxiv - Bioengineering 2024Quote: ... and plated at a minimum density of 1.5 x 105 cells/well of a Matrigel-coated 6-well plate in mTeSR™ with Y-27632 dihydrochloride (10µM, cat: 1254, Tocris Bioscience), which was removed from culture medium after 1 day ...
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bioRxiv - Cell Biology 2024Quote: ... One million cells were plated per well of a Geltrex-coated 6-well plate in E6 medium (Thermo A1516401) supplemented with 10 μM ROCK inhibitor Y-27632 (Tocris 1254).
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bioRxiv - Developmental Biology 2021Quote: ... From passage 3 cells were grown NMP differentiation medium supplemented with 5 μM Y-27632 (Tocris). Human iPSCs were found to detach more readily than hESCs ...
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bioRxiv - Developmental Biology 2020Quote: ... short-term serum-free culture was carried out in N2B27 supplemented with 3 μM CHIR99201 (Tocris), 1 μg/ml of Heparin (Sigma ...
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bioRxiv - Developmental Biology 2020Quote: ... mTeSR Plus was replaced with the N2B27 basal medium supplemented with 3 μM CHIR99021 (Tocris Bioscience) and 40 ng/ml basic fibroblast growth factor bFGF/FGF2 (R&D Systems) ...
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bioRxiv - Neuroscience 2020Quote: ... each disk with neurons was transferred into the physiological saline solution containing NBQX (3 μM, Tocris) and bicuculine (30 μM ...
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bioRxiv - Bioengineering 2021Quote: ... Plates were centrifuged at 100xg for 3 minutes in E8 medium containing 10 μM Y27632 (Tocris). The following day ...
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bioRxiv - Neuroscience 2023Quote: ... KA (3 mg/mL) was prepared on the day of experimentation by dissolving KA (Tocris, 0222) in a 0.9% bacteriostatic saline solution ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Neuroscience 2023Quote: The neural activity was reversibly suppressed using the GABA-A agonist 4,5,6,7-tetrahydro isoxazole [5,4-c]-pyridine-3-ol (THIP hydrochloride; Tocris). The THIP was dissolved in phosphate-buffered saline (PBS) ...
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bioRxiv - Neuroscience 2021Quote: ... 4-methoxy-7-nitroindoline-caged L-glutamate (MNI- caged-glutamate, 2.5 mM, Tocris Bioscience) was added to the bath solution ...
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bioRxiv - Neuroscience 2021Quote: ... L-(+)-2-amino-4-phosphonobutyric acid (L-AP4, 50 μM, Tocris Bioscience, Bristol, UK) were diluted to the appropriate concentration from stock solutions and added to the bath through the perfusion system for 10 minutes before recordings ...
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bioRxiv - Neuroscience 2021Quote: ... L-(+)-2-amino-4-phosphonobutyric acid (L-AP4, 50 μM, Tocris Bioscience, Bristol, UK) were diluted to the appropriate concentration from stock solutions and added to the Ames medium before recordings.
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bioRxiv - Cell Biology 2022Quote: At day 0 cells were treated with 5 nM 4-Hydroxytamoxifen (+HOT) (Tocris, 3412) or with vehicle (-HOT ...