Labshake search

5151 - 5200 of 7257 citations since 2019

• Angiotensin-II modulates GABAergic neurotransmission in the mouse substantia nigra

  Maibam R. Singh, Jozsef Vigh, Gregory C. Amberg, bioRxiv - Neuroscience 2021

  Quote: ... and TTX and PD123319 from Tocris Biosciences ...
• Neuronal activity promotes nuclear proteasome-mediated degradation of PDCD4 to regulate activity-dependent transcription

  Wendy A. Herbst, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1 μM tetrodotoxin (TTX, Tocris) was applied to the neurons for 1 hr ...
• Impaired refinement of kinematic variability in Huntington disease mice on an automated home-cage forelimb motor task

  Cameron L. Woodard, et al., bioRxiv - Neuroscience 2021

  Quote: ... slices were continuously superfused with room temperature aCSF containing picrotoxin (50μM; Tocris Bioscience) to block GABAA receptors and minimize inhibitory responses ...
• Spatially displaced excitation contributes to the encoding of interrupted motion by the retinal direction-selective circuit

  Jennifer Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... 8 μM Dihydro-b-erythroidine hydrobromide (DHβE; Tocris, Cat#2349); 10 μM SR 9551 hydrobromide (gabazine ...
• Spatially displaced excitation contributes to the encoding of interrupted motion by the retinal direction-selective circuit

  Jennifer Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... 50 μM TPMPA (Tocris, Cat#1040 ...
• Spatially displaced excitation contributes to the encoding of interrupted motion by the retinal direction-selective circuit

  Jennifer Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... 10 μM SR 9551 hydrobromide (gabazine; Tocris, Cat #1262); 100 μM Meclofenamic acid sodium salt (MFA ...
• Spatially displaced excitation contributes to the encoding of interrupted motion by the retinal direction-selective circuit

  Jennifer Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... 50 μM TPMPA (Tocris, Cat#1040; 50 μM Carbenoxolone disodium (Tocris, Cat#3096).
• Daily orexinergic modulation of the rat superficial layers of the superior colliculus – implications for intrinsic clock activities in the visual system

  Lukasz Chrobok, et al., bioRxiv - Neuroscience 2021

  Quote: ... TCS-OX2-29 (20 μM, Tocris, Bristol, UK) and bicuculline (20 μM ...
• Daily orexinergic modulation of the rat superficial layers of the superior colliculus – implications for intrinsic clock activities in the visual system

  Lukasz Chrobok, et al., bioRxiv - Neuroscience 2021

  Quote: ... and bicuculline (20 μM, Tocris).
• Cerebellar connectivity maps embody individual adaptive behavior

  Ludovic Spaeth, et al., bioRxiv - Neuroscience 2021

  Quote: ... CGP 52432 0.001 and JNJ16259685 0.002 (Tocris-Cookson, UK). For excitatory maps only ...
• An ultrasensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... HA (Tocris), ACh (Solarbio) ...
• An ultrasensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... NE (Tocris), 5-HT (Tocris) ...
• An ultrasensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... 5-HT (Tocris), HA (Tocris) ...
• An ultrasensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... MRS-2500 (Tocris), Glu (Sigma) ...
• An ultrasensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... GABA (Tocris), Gly (Sigma) ...
• Dual mechanisms of opioid-induced respiratory depression in the inspiratory rhythm-generating network

  Nathan A Baertsch, et al., bioRxiv - Neuroscience 2021

  Quote: ... Naloxone (Tocris) was diluted to a 100 mM stock solution in H2O ...
• Dual mechanisms of opioid-induced respiratory depression in the inspiratory rhythm-generating network

  Nathan A Baertsch, et al., bioRxiv - Neuroscience 2021

  Quote: ... CNQX and CPP (Tocris) were diluted to 20 mM stock solutions in H2O ...
• Enhanced preference for delayed rewards requires the basolateral amygdala and retrosplenial cortex

  Merridee J. Lefner, et al., bioRxiv - Neuroscience 2021

  Quote: ... OFC-lesioned rats received injections of NMDA (12.5 μg/μL in saline vehicle; Tocris) at the following locations (relative to bregma) ...
• Enhanced preference for delayed rewards requires the basolateral amygdala and retrosplenial cortex

  Merridee J. Lefner, et al., bioRxiv - Neuroscience 2021

  Quote: ... Injections of flupenthixol (225 μg/kg i.p., Tocris) or saline were administered 1 hour prior to training sessions ...
• Protein Kinase D promotes activity-dependent AMPA receptor endocytosis in hippocampal neurons

  Carlos O. Oueslati Morales, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 50 μM D-AP5 (Tocris #3693) for 2 minutes in conditioned medium ...
• Protein Kinase D promotes activity-dependent AMPA receptor endocytosis in hippocampal neurons

  Carlos O. Oueslati Morales, et al., bioRxiv - Neuroscience 2021

  Quote: ... protein lysosomal degradation was inhibited with 100 μg/ml Leupeptin (Tocris, #1167) for 1h ...
• FAM57B is a modulator of ceramide synthesis that regulates sphingolipid homeostasis and synaptic composition in the developing brain

  Danielle L. Tomasello, et al., bioRxiv - Neuroscience 2021

  Quote: ... D-Glucose and NaCl) plus dorsomorphin (Tocris) every day over 2-3 weeks ...
• Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition

  Ruchi Malik, et al., bioRxiv - Neuroscience 2021

  Quote: ... and d-2-amino-5-phosphonopentanoic acid (D-AP5) (Tocris). Drugs were prepared as concentrated stock solutions and were diluted in ACSF on the day of the experiment.
• Daily changes in neuronal activities of the dorsal motor nucleus of the vagus under standard and short-term high fat diet – implications for circadian modulation of parasympathetic outflow

  Lukasz Chrobok, et al., bioRxiv - Neuroscience 2021

  Quote: ... tetrodotoxin citrate (TTX; 0.5 µM, Tocris) were stocked at 100x concentration at -20°C and were freshly diluted in the recording ACSF prior the application by bath perfusion.
• Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum

  Marta Maltese, et al., bioRxiv - Neuroscience 2021

  Quote: Drugs (all from Tocris, unless specified otherwise) were reconstituted and stored according to the manufacturers’ recommendations ...
• CaSR modulates sodium channel-mediated Ca²⁺-dependent excitability

  Briana J. Martiszus, et al., bioRxiv - Neuroscience 2021

  Quote: ... KB-R7943 Mesylate was supplied by Tocris. Creatine Phosphate was supplied by Santa Cruz Biotech ...
• Mature parvalbumin interneuron function in prefrontal cortex requires activity during a postnatal sensitive period

  Sarah E. Canetta, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 50 µM D-(-)-2-amino-5-phosphonopentanoic acid (AP5, Tocris Bioscience) were added to the bath to block glutamatergic currents ...
• Mature parvalbumin interneuron function in prefrontal cortex requires activity during a postnatal sensitive period

  Sarah E. Canetta, et al., bioRxiv - Neuroscience 2021

  Quote: ... 20 µM 6-cyano-7-nitroquinoxaline-2,3-dione disodium salt (CNQX, Tocris Bioscience, Briston, UK) and 50 µM D-(-)-2-amino-5-phosphonopentanoic acid (AP5 ...
• Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca²⁺ channel activity in continuously active midbrain dopamine neurons

  Anita Siller, et al., bioRxiv - Neuroscience 2021

  Quote: ... all Cav Blocker were from Tocris. Steady-state activation and inactivation curves were fitted as described above.
• Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca²⁺ channel activity in continuously active midbrain dopamine neurons

  Anita Siller, et al., bioRxiv - Neuroscience 2021

  Quote: ... 4 µM SR 95531 (Tocris) and 10 µM DL-AP5 (Tocris) ...
• Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca²⁺ channel activity in continuously active midbrain dopamine neurons

  Anita Siller, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 10 µM DL-AP5 (Tocris), pH adjusted to 7.4 ...
• Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca²⁺ channel activity in continuously active midbrain dopamine neurons

  Anita Siller, et al., bioRxiv - Neuroscience 2021

  Quote: ... 600 nM TTX (Tocris), 20 µM CNQX (Tocris) ...
• Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca²⁺ channel activity in continuously active midbrain dopamine neurons

  Anita Siller, et al., bioRxiv - Neuroscience 2021

  Quote: ... 20 µM CNQX (Tocris), 4 µM SR 95531 (Tocris ...
• Modulation of tactile feedback for the execution of dexterous movement

  James M. Conner, et al., bioRxiv - Neuroscience 2021

  Quote: ... Strychnine (10 μM, Tocris) was used to block glycine-mediated transmission ...
• Forced swim stress dynamically alters neural activity and bi-directionally modulates NMDA receptors in the prefrontal cortex

  Marc-Alexander L.T. Parent, et al., bioRxiv - Neuroscience 2021

  Quote: ... and ifenprodil were purchased from Tocris, and TTX from Alomone.
• Examination of the contribution of Nav1.7 to axonal propagation in nociceptors

  George Goodwin, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 4,9-Anhydrotetrodotoxin (Tocris, UK) were dissolved to 1mM in 0.2 mM citric acid (pH 4.8) ...
• Chronic neuronal excitation leads to homeostatic suppression of structural long-term potentiation

  Hiromi H. Ueda, et al., bioRxiv - Neuroscience 2021

  Quote: ... SR95531 (gabazine) and 4-methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate) were purchased from Tocris Bioscience (Bristol ...
• Caveolae mediated endocytosis of VLDL particles in macrophages requires NPC1 and STARD3 for further lysosomal processing

  Lei Deng, et al., bioRxiv - Cell Biology 2021

  Quote: ... GSK264220A was from Tocris (bio-techne), Abingdon ...
• MIF-2/D-DT is an atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis

  Omar El Bounkari, et al., bioRxiv - Immunology 2021

  Quote: ... The non-selective MIF family cytokine inhibitor 4-IPP was obtained from Tocris Bioscience.
• Genuine Selective Caspase-2 Inhibition with new Irreversible Small Peptidomimetics

  Elodie Bosc, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: Lyophilized and HPLC-purified Human β-Amyloid1-42 (Aβ1-42) peptide was purchased from Tocris (#1428). 1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP ...
• BLOCKADE OF M4 MUSCARINIC RECEPTORS ON STRIATAL CHOLINERGIC INTERNEURONS NORMALIZES STRIATAL DOPAMINE RELEASE IN A MOUSE MODEL OF TOR1A DYSTONIA

  Anthony M. Downs, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Dihydro-β-erythroidine (DHβE) was obtained from Tocris (Minneapolis, MN). VU6021625 was generously provided by Dr ...
• Inhibition of the sodium-dependent HCO₃^- transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype

  Vinciane Saint-Criq, et al., bioRxiv - Physiology 2021

  Quote: ... 37°C) and grown in medium containing the ROCK inhibitor Y-27632 (10 mM, Tocris Biotechne, #1254) until they reached 80% confluence ...
• Inhibition of the sodium-dependent HCO₃^- transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype

  Vinciane Saint-Criq, et al., bioRxiv - Physiology 2021

  Quote: ... and forskolin (Tocris Biotechne #1099) and S0859 were added basolaterally at indicated times ...
• Neuron-like function of the nephron central command

  Georgina Gyarmati, et al., bioRxiv - Physiology 2021

  Quote: ... LM11a 31 dihydrochloride (LM11a, 25mg/kg, Tocris, Minneapolis, MN), or amyloid precursor protein (0.6 mg/kg ...
• Potassium effects on NCC are attenuated during inhibition of Cullin E3-ubiquitin ligases

  Sathish K Murali, et al., bioRxiv - Physiology 2021

  Quote: ... For experiments involving the general WNK inhibitor stock2s (Tocris) and MLN4924 ...
• LRH-1/NR5A2 regulates the PTGS2-PGE₂-PTGER1 signalling axis contributing to islet survival and antidiabetic actions of the agonist BL001

  Eugenia Martin Vázquez, et al., bioRxiv - Physiology 2021

  Quote: ... and/or 4) 100 nM ONO-8130 (Tocris Bioscience, Bristol, UK). In the latter two conditions ...
• Mast cell-specific receptor/corticotropin-releasing factor axis regulates alcohol withdrawal-associated headache

  Hyeonwi Son, et al., bioRxiv - Neuroscience 2021

  Quote: ... and astressin were purchase from Tocris Bioscience/ Bio-Techne Corporation (Minneapolis ...
• Chemoproteomics of microbiota metabolites reveals small-molecule agonists for orphan receptor GPRC5A

  Xiaohui Zhao, et al., bioRxiv - Biochemistry 2021

  Quote: ... clonidine hydrochloride (Tocris, Catalog #0690), pyridoxal-5’-phosphate (Oakwood Chemical ...
• Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells

  Matias I. Autio, et al., bioRxiv - Bioengineering 2021

  Quote: ... ROCK inhibitor (1254, Tocris) was added (final concentration 10μM ...
• Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells

  Matias I. Autio, et al., bioRxiv - Bioengineering 2021

  Quote: ... 3 μM CHIR99021 (Tocris) and 10 μM LY294002 (LC Labs ...