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251 - 300 of 857 citations for 5 Pyrimidinecarboxaldehyde 2 1 1 dimethylethyl 9CI since 2019

• Pharmacologic Targeting of PDIA1 Inhibits NLRP3 Inflammasome Assembly and Activation

  Jessica D. Rosarda, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (1:1000, GeneTex cat. GTX627408), NEK7 (1:1000 ...
• Nitric Oxide modulates spontaneous Ca²⁺ release and ventricular arrhythmias during β-adrenergic signalling through S-nitrosylation of Calcium/Calmodulin dependent kinase II

  Amelia S. Power, et al., bioRxiv - Physiology 2023

  Quote: ... and GAPDH (1:10000, GeneTex GTX627408) for a loading control ...
• Sexually dimorphic dynamics of the microtubule network in medaka (Oryzias latipes) germ cells

  Mariko Kikuchi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... γ-tubulin (1:100, rabbit, GeneTex, GTX113286). The secondary antibodies ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-HGS (1:200; Genetex, GTX101718), anti-MAP2 (1:1000 ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CHMP2B (1:100; GeneTex, GTX118181), anti-Galectin-3 (1:50 ...
• PARG inhibition induces nuclear aggregation of PARylated PARP1

  Sateja Paradkar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Histone H3 (GeneTex, 1:1000), anti-GAPDH (Proteintech ...
• SART1 localizes to spindle poles forming a SART1 cap and promotes spindle pole assembly

  Hideki Yokoyama, et al., bioRxiv - Cell Biology 2023

  Quote: ... Ndc80 (Ms, GeneTex, IF 1:500), phospho-Histone H3 (Rb ...
• Structural and functional characterisation of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA Polymerase II

  Jeremy Keown, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit anti-NP (1:5000) (Genetex), and rabbit anti-GAPDH (1:1000 ...
• CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair

  Lu Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or RAD51 (GeneTex, GTX70230, 1:500). Coverslips were mounted onto slides using ProLong Glass antifade medium containing NucBlue nuclear counterstain (Thermo Fisher Scientific) ...
• Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8

  Yannick Perez, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-RNF168 (1:100, GTX129617, Genetex), anti-RAD51 (1:500 ...
• APE1 associates with 60S ribosomes and tRNAs and regulates the expression of IGF2BP1

  Wai Ming Li, Belal Tafech, Chow H. Lee, bioRxiv - Biochemistry 2023

  Quote: ... anti-RPS2 (N2C3, 1:1000, GeneTex); anti-LAMP1 (D2D11 ...
• Cyclin A/Cdk1 promotes chromosome alignment and timely mitotic progression

  Sarah Y. Valles, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cyclin A (1:400; GeneTex; GTX634420), H2ApT120 (1:1000 ...
• Influenza A virus NS1 effector domain is required for PA-X mediated host shutoff

  Juliette Bougon, et al., bioRxiv - Microbiology 2023

  Quote: ... PA (1:1000, rabbit, GeneTex, GTX125932), PABPN1 (1:1000 ...
• Human MX1 orchestrates the cytoplasmic sequestration of neo-synthesized influenza A virus vRNPs

  Joe McKellar, et al., bioRxiv - Microbiology 2024

  Quote: ... NS2/NEP (GeneTex, GTX125953, 1/150), TGN46 (BioRad ...
• The NRF2/ID2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging

  Mulin Xu, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Nrf2 (GTX103322, 1:500, GeneTex, USA). The fluorescence signal was monitored by confocal laser scanning microscopy (Nikon C2+ ...
• The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy

  Yurika Ito, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-MuRF1 (diluted 1/2000, GeneTex), anti-FBXO32 (diluted 1/2000 ...
• RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

  Leïla Dumas, et al., bioRxiv - Cancer Biology 2024

  Quote: ... B4GALT1 (1:1000, GeneTex GTX131598-S), SOD2 (1:1000 ...
• The Rab32/BLOC-3 dependent pathway mediates host- defence against different pathogens in human macrophages

  Massimiliano Baldassarre, et al., bioRxiv - Microbiology 2020

  Quote: ... in PBS and incubated for 1 hour with a rabbit polyclonal anti-Rab32 (GeneTex, 1:200 dilution). Cells were then stained using the appropriate Alexa Fluor® 488 or Alexa Fluor® 555-conjugated secondary antibodies (Invitrogen) ...
• Staufen1 localizes to the mitotic spindle and controls the transport of RNA populations to the spindle

  Sami Hassine, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Anti-RPL26, (GTX101833. 1/1000) and anti-STAU1 (for IF, GTX106566. 1/200) was obtained from Genetex. Goat polyclonal anti-mouse (p0447 ...
• Confined Migration Induces Heterochromatin Formation and Alters Chromatin Accessibility

  Chieh-Ren Hsia, et al., bioRxiv - Cell Biology 2021

  Quote: ... and then incubated overnight at 4°C with primary antibodies (rabbit anti-H3K9me3, Abcam, ab8898, 1:3,000; rabbit anti-H3K27me3, Millipore, 07-449, 1:3,000; mouse anti-H3K9ac, GeneTex, GT464 ...
• Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression

  Tommaso Montecchi, et al., bioRxiv - Cancer Biology 2023

  Quote: The surface expression of PD-1 was assessed by labeling transfected T cells with anti-PD-1 (Genetex) primary antibody and Alexa Fluor-647 anti-mouse secondary antibody (Thermo Fisher Scientific ...
• Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

  Mounir El-Maï, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-g-H2AX (1:1000, GeneTex, GTX127342); anti-p16 (F-12 ...
• Repression of MAPK/Erk signaling by Efnb2-Ephb4-Rasa1 is required for lymphatic valve formation

  Yaping Meng, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-Prox1 (1/200; GeneTex, GTX128354), chicken anti-GFP (1/200 ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti-GAPDH (GeneTex, GTX627408; 1:10000), mouse anti-Ku86 (Santa Cruz ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-GAPDH (GeneTex, GTX100118, 1:5000); and rabbit anti-alpha tubulin (Cell Signaling ...
• Autophagy receptor NDP52 alters DNA conformation to modulate RNA Polymerase II transcription

  Ália dos Santos, et al., bioRxiv - Biophysics 2022

  Quote: ... rabbit anti-NDP52 (1:200, Genetex GTX115378) antibodies were used ...
• A Combinatorial MAP Code Dictates Polarized Microtubule Transport

  Brigette Y. Monroy, et al., bioRxiv - Biophysics 2019

  Quote: ... 1:500 anti-chicken tau (Genetex GTX49353), 1:500 anti-rabbit MAP2 (Sigma M3696) ...
• mDia2 formin selectively interacts with catenins and not E-cadherin to regulate Adherens Junction formation

  Yuqi Zhang, et al., bioRxiv - Cell Biology 2019

  Quote: ... 1:100 mouse anti-αE-catenin (GeneTex), 1:100 mouse anti-β-catenin (Origene) ...
• PP1 and PP2A use opposite phospho-dependencies to control distinct processes at the kinetochore

  Richard J Smith, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit α-mCherry (GTX128508, Genetex,1:1000). The rabbit α-pMELT-Knl1 antibody is directed against Thr 943 and Thr 1155 of human Knl1 (Nijenhuis et al. ...
• Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

  Ryoji Amamoto, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit Iba1 (1:500, GeneTex, cat. #GTX100042), mouse Glutamine Synthetase (1:3000 ...
• The Exon Junction Complex Core Represses Caner-specific Mature mRNA Re-splicing: A Potential Key Role in Terminating Splicing

  Yuta Otani, et al., bioRxiv - Molecular Biology 2021

  Quote: ... RBM8A (1:1000; GeneTex, Irvine, CA, USA), and MAGOH (1:1000 ...
• Retrograde transport of mannose-6-phosphate receptor depends on several sorting machineries as analyzed by sulfatable nanobodies

  Dominik P. Buser, Martin Spiess, bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-mCherry (GeneTex #GTX128508; 1:10000), rabbit anti-T7 (Bethyl Laboratories #A190-117A ...
• Bi-allelic MCM10 mutations cause telomere shortening with immune dysfunction and cardiomyopathy

  Ryan M. Baxley, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse anti-GAPDH (GeneTex GTX627408; 1:5,000), mouse anti-<ι>α-Tubulin (Millipore T9026 ...
• Regulation of KHNYN antiviral activity by the extended di-KH domain and nucleo-cytoplasmic trafficking

  María José Lista, et al., bioRxiv - Microbiology 2021

  Quote: ... 1:5000 anti-HSP90 (Rabbit, GeneTex, GTX109753), 1:1000 anti-FLAG (DYKDDDDK ...
• The E3 ubiquitin ligase RNF216/TRIAD3 is a central regulator of the hypothalamic-pituitary-gonadal axis

  Arlene J. George, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-β-Actin (Genetex, 1:3,000) and were incubated overnight at 4°C ...
• OSCAR: a framework to identify and quantify cells in densely packed three-dimensional biological samples

  Mario Ledesma-Terrón, et al., bioRxiv - Systems Biology 2021

  Quote: ... rabbit anti-Sox2 (1:1000, GeneTex GTX124477), mouse anti-PCNA (1:100 ...
• Viral-mediated ubiquitination impacts interactions of host proteins with viral RNA and promotes viral RNA processing

  Christin Herrmann, et al., bioRxiv - Microbiology 2020

  Quote: ... RAD50 (GeneTex, Catalog#: GTX70228, WB 1:1000) and USP7 (Bethyl Laboratories ...
• Extracellular Matrix Dysfunction in Sorsby Patient-Derived Retinal Pigment Epithelium

  Abbi L. Engel, et al., bioRxiv - Cell Biology 2021

  Quote: ... TIMP3 (1:5000, GTX25939, GeneTex, Irvine, CA), and Vitronectin (1:1000 ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... mouse anti-GAPDH 1:10,000 (GeneTex, GTX28245), rabbit anti-GAPDH 1:10,000 (GeneTex ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit anti-GAPDH 1:10,000 (GeneTex, GTX100118), anti-pUL16 1:2000 (Carmichael and Wills ...
• Oncogene-induced cardiac neoplasia shares similar mechanisms with heart regeneration in zebrafish

  Catherine Pfefferli, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit Myl7 1:200 at (GTX128346, GeneTex), mouse anti-A4.1025 at (developed by H.M ...
• Chromosome length and gene density contribute to micronuclear membrane stability

  Anna E Mammel, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-CENPA (1:100; GTX13939, GeneTex), mouse or rabbit anti-H3K27ac (1:250 ...
• Visualizing cancer-originated acetate uptake through MCT1 in reactive astrocytes demarcates tumor border and extends survival in glioblastoma patients

  Hae Young Ko, et al., bioRxiv - Cancer Biology 2022

  Quote: ... goat anti-rabbit-HRP (GeneTex, 1:2000). Immunoreactive protein bands were visualized via enhanced chemiluminescence and scanned with a LAS-4000 system (GE Healthcare).
• Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation

  Alex F. Thompson, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-KIF22 1:500 (GeneTex #GTX112357), mouse anti-centrin 1:500 (Millipore Sigma #04-1624) ...
• A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods

  Maria Jose Lista, et al., bioRxiv - Microbiology 2022

  Quote: ... 1:5000 anti-HSP90 (Rabbit, GeneTex, GTX109753), 1:1000 anti- FLAG (DYKDDDDK ...
• Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections

  Michel Fries, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-POU3F1 rabbit (1:100, Genetex, GTX134063), anti-POU3F1 mouse (1:100 ...
• The mRNA cap 2’O methyltransferase CMTR1 regulates the expression of certain interferon-stimulated genes

  Graham D. Williams, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-GAPDH (GeneTex, GT239, 1:1000) mouse anti-STAT1 (BD ...
• Sequestration of LINE-1 in novel cytosolic bodies by MOV10 restricts retrotransposition

  Rajika Arora, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-DDX6 (1:2000, GTX102795 GeneTex), anti-rabbit IgG HRP-linked (1:10000 7074 ...
• Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity

  Beatriz Gomez Perez-Nievas, et al., bioRxiv - Neuroscience 2021

  Quote: ... MAP2 (Mouse IgG, #GTX8266, GeneTex, 1/200), and GFAP (Rabbit IgG ...
• Myostatin is a negative regulator of adult neurogenesis in zebrafish

  Vishnu Muraleedharan Saraswathy, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-PCNA (GeneTex, GTX124496, 1:500), mouse anti-HuC/D (Invitrogen ...