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251 - 300 of 775 citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020

• Spinal motor neuron development and metabolism are transcriptionally regulated by Nuclear Factor IA

  Julia Gauberg, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-GFP (Genetex, 1:700), rabbit anti-Isl1 (Abcam ...
• Influenza A virus circumvents the innate immune response through the sequestration of double-stranded RNA

  Masahiro Nakano, et al., bioRxiv - Microbiology 2024

  Quote: ... NA (1:1000 dilution, GTX125974; GeneTex), and M1 (1:1000 dilution ...
• Influenza A virus circumvents the innate immune response through the sequestration of double-stranded RNA

  Masahiro Nakano, et al., bioRxiv - Microbiology 2024

  Quote: ... NS1 (1:1000 dilution, GTX125990; GeneTex), NEP (1:1000 dilution ...
• Influenza A virus circumvents the innate immune response through the sequestration of double-stranded RNA

  Masahiro Nakano, et al., bioRxiv - Microbiology 2024

  Quote: ... NEP (1:1000 dilution, GTX125953; GeneTex), NA (1:1000 dilution ...
• A phosphorylation code coordinating transcription condensate dynamics with DNA replication

  Carlos Origel Marmolejo, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-H1.2 (1:500, GeneTex, GTX122561), anti-H1.3 (1:1000 ...
• Self-Organization of Sinusoidal Vessels in Pluripotent Stem Cell-derived Human Liver Bud Organoids

  Norikazu Saiki, et al., bioRxiv - Developmental Biology 2024

  Quote: ... anti-GS (GeneTex, GTX630657, 1:250), anti-GLS2 (Abcam ...
• Proteomic Profiling of Mesenchymal Stem Cell-Derived Extracellular Vesicles: Impact of Isolation Methods on Protein Cargo

  Morteza Abyadeh, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-TSG101 (Gtx70255, Genetex; 1:1000) and anti-calnexin (Sc11397 ...
• SNX10 regulates the clearance of mitochondrial proteins and mitochondrial bioenergetics

  Laura Trachsel-Moncho, et al., bioRxiv - Cell Biology 2024

  Quote: ... alpha Tubulin (GeneTex, GTX628802. 1:5000). Primary antibodies used for immunostaining ...
• The Rubicon-WIPI axis regulates exosome biogenesis during aging

  Kyosuke Yanagawa, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-HRS (GeneTex, GTX101718, 1:1000), anti-VPS4 (Sigma-Aldrich ...
• RNA promotes mitochondrial import of F1-ATP synthase subunit alpha (ATP5A1)

  Aindrila Chatterjee, et al., bioRxiv - Cell Biology 2024

  Quote: ... HNRNPC1/C2 (Genetex #14676-1-AP), H3 (Sigma ...
• The Rab32/BLOC-3 dependent pathway mediates host- defence against different pathogens in human macrophages

  Massimiliano Baldassarre, et al., bioRxiv - Microbiology 2020

  Quote: ... in PBS and incubated for 1 hour with a rabbit polyclonal anti-Rab32 (GeneTex, 1:200 dilution). Cells were then stained using the appropriate Alexa Fluor® 488 or Alexa Fluor® 555-conjugated secondary antibodies (Invitrogen) ...
• Staufen1 localizes to the mitotic spindle and controls the transport of RNA populations to the spindle

  Sami Hassine, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Anti-RPL26, (GTX101833. 1/1000) and anti-STAU1 (for IF, GTX106566. 1/200) was obtained from Genetex. Goat polyclonal anti-mouse (p0447 ...
• Confined Migration Induces Heterochromatin Formation and Alters Chromatin Accessibility

  Chieh-Ren Hsia, et al., bioRxiv - Cell Biology 2021

  Quote: ... and then incubated overnight at 4°C with primary antibodies (rabbit anti-H3K9me3, Abcam, ab8898, 1:3,000; rabbit anti-H3K27me3, Millipore, 07-449, 1:3,000; mouse anti-H3K9ac, GeneTex, GT464 ...
• Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression

  Tommaso Montecchi, et al., bioRxiv - Cancer Biology 2023

  Quote: The surface expression of PD-1 was assessed by labeling transfected T cells with anti-PD-1 (Genetex) primary antibody and Alexa Fluor-647 anti-mouse secondary antibody (Thermo Fisher Scientific ...
• Protective Effects of Butyrate on Retinal Neovascularization in Preclinical Retinopathy of Prematurity Models

  Allston Oxenrider, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... GFAP (1:1000, Abacm Waltham, Boston, MA, USA) and RBPMS (1:500, Genetex, Alton Pkwy Irvine, CA USA). After immunoblotting ...
• Sox10 is required for systemic initiation of bone mineralization

  Stefani Gjorcheska, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Primary antibodies included anti-Na+/K+ ATPase (1:400, DSHB α5) and anti-Sox10 (1:500, Genetex GTX128374), used with AlexaFluor 647-conjugated goat anti-mouse and donkey anti-rabbit secondary antibodies (1:250 ...
• Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

  Mounir El-Maï, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-g-H2AX (1:1000, GeneTex, GTX127342); anti-p16 (F-12 ...
• Repression of MAPK/Erk signaling by Efnb2-Ephb4-Rasa1 is required for lymphatic valve formation

  Yaping Meng, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-Prox1 (1/200; GeneTex, GTX128354), chicken anti-GFP (1/200 ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti-GAPDH (GeneTex, GTX627408; 1:10000), mouse anti-Ku86 (Santa Cruz ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-GAPDH (GeneTex, GTX100118, 1:5000); and rabbit anti-alpha tubulin (Cell Signaling ...
• Autophagy receptor NDP52 alters DNA conformation to modulate RNA Polymerase II transcription

  Ália dos Santos, et al., bioRxiv - Biophysics 2022

  Quote: ... rabbit anti-NDP52 (1:200, Genetex GTX115378) antibodies were used ...
• Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

  Ryoji Amamoto, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit Iba1 (1:500, GeneTex, cat. #GTX100042), mouse Glutamine Synthetase (1:3000 ...
• The Exon Junction Complex Core Represses Caner-specific Mature mRNA Re-splicing: A Potential Key Role in Terminating Splicing

  Yuta Otani, et al., bioRxiv - Molecular Biology 2021

  Quote: ... RBM8A (1:1000; GeneTex, Irvine, CA, USA), and MAGOH (1:1000 ...
• Bi-allelic MCM10 mutations cause telomere shortening with immune dysfunction and cardiomyopathy

  Ryan M. Baxley, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse anti-GAPDH (GeneTex GTX627408; 1:5,000), mouse anti-<ι>α-Tubulin (Millipore T9026 ...
• Regulation of KHNYN antiviral activity by the extended di-KH domain and nucleo-cytoplasmic trafficking

  María José Lista, et al., bioRxiv - Microbiology 2021

  Quote: ... 1:5000 anti-HSP90 (Rabbit, GeneTex, GTX109753), 1:1000 anti-FLAG (DYKDDDDK ...
• The E3 ubiquitin ligase RNF216/TRIAD3 is a central regulator of the hypothalamic-pituitary-gonadal axis

  Arlene J. George, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-β-Actin (Genetex, 1:3,000) and were incubated overnight at 4°C ...
• OSCAR: a framework to identify and quantify cells in densely packed three-dimensional biological samples

  Mario Ledesma-Terrón, et al., bioRxiv - Systems Biology 2021

  Quote: ... rabbit anti-Sox2 (1:1000, GeneTex GTX124477), mouse anti-PCNA (1:100 ...
• Viral-mediated ubiquitination impacts interactions of host proteins with viral RNA and promotes viral RNA processing

  Christin Herrmann, et al., bioRxiv - Microbiology 2020

  Quote: ... RAD50 (GeneTex, Catalog#: GTX70228, WB 1:1000) and USP7 (Bethyl Laboratories ...
• Extracellular Matrix Dysfunction in Sorsby Patient-Derived Retinal Pigment Epithelium

  Abbi L. Engel, et al., bioRxiv - Cell Biology 2021

  Quote: ... TIMP3 (1:5000, GTX25939, GeneTex, Irvine, CA), and Vitronectin (1:1000 ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... mouse anti-GAPDH 1:10,000 (GeneTex, GTX28245), rabbit anti-GAPDH 1:10,000 (GeneTex ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit anti-GAPDH 1:10,000 (GeneTex, GTX100118), anti-pUL16 1:2000 (Carmichael and Wills ...
• Oncogene-induced cardiac neoplasia shares similar mechanisms with heart regeneration in zebrafish

  Catherine Pfefferli, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit Myl7 1:200 at (GTX128346, GeneTex), mouse anti-A4.1025 at (developed by H.M ...
• Chromosome length and gene density contribute to micronuclear membrane stability

  Anna E Mammel, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-CENPA (1:100; GTX13939, GeneTex), mouse or rabbit anti-H3K27ac (1:250 ...
• Visualizing cancer-originated acetate uptake through MCT1 in reactive astrocytes demarcates tumor border and extends survival in glioblastoma patients

  Hae Young Ko, et al., bioRxiv - Cancer Biology 2022

  Quote: ... goat anti-rabbit-HRP (GeneTex, 1:2000). Immunoreactive protein bands were visualized via enhanced chemiluminescence and scanned with a LAS-4000 system (GE Healthcare).
• Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation

  Alex F. Thompson, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-KIF22 1:500 (GeneTex #GTX112357), mouse anti-centrin 1:500 (Millipore Sigma #04-1624) ...
• A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods

  Maria Jose Lista, et al., bioRxiv - Microbiology 2022

  Quote: ... 1:5000 anti-HSP90 (Rabbit, GeneTex, GTX109753), 1:1000 anti- FLAG (DYKDDDDK ...
• Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections

  Michel Fries, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-POU3F1 rabbit (1:100, Genetex, GTX134063), anti-POU3F1 mouse (1:100 ...
• The mRNA cap 2’O methyltransferase CMTR1 regulates the expression of certain interferon-stimulated genes

  Graham D. Williams, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-GAPDH (GeneTex, GT239, 1:1000) mouse anti-STAT1 (BD ...
• Sequestration of LINE-1 in novel cytosolic bodies by MOV10 restricts retrotransposition

  Rajika Arora, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-DDX6 (1:2000, GTX102795 GeneTex), anti-rabbit IgG HRP-linked (1:10000 7074 ...
• Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity

  Beatriz Gomez Perez-Nievas, et al., bioRxiv - Neuroscience 2021

  Quote: ... MAP2 (Mouse IgG, #GTX8266, GeneTex, 1/200), and GFAP (Rabbit IgG ...
• Myostatin is a negative regulator of adult neurogenesis in zebrafish

  Vishnu Muraleedharan Saraswathy, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-PCNA (GeneTex, GTX124496, 1:500), mouse anti-HuC/D (Invitrogen ...
• Myostatin is a negative regulator of adult neurogenesis in zebrafish

  Vishnu Muraleedharan Saraswathy, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Sox2 (GeneTex, 124477, 1:250). Secondary antibodies (Invitrogen ...
• ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain of function

  Devesh C. Pant, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-β actin (1:2000; GeneTex) overnight at 4°C followed by HRP-conjugated secondary antibodies (ABclonal ...
• CRISPR metabolic screen identifies ATM and KEAP1 as targetable genetic vulnerabilities in solid tumors

  Haojian Li, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p53 (1:1000; GTX70214, GeneTex, CA, USA); Phospho-p53 (1:1000 ...
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... type 6a1 collagen (GTX109963, Genetex, 1:300), α-Smooth muscle actin (aSMA ...
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... type 6a1 collagen (GTX109963, Genetex, 1:3000), laminin B2 (sc-59980 ...
• Fibroblast growth factor 9 stimulates neurite outgrowth through NF-kB signaling in striatal cell Huntington’s disease models

  Issa Olakunle Yusuf, et al., bioRxiv - Neuroscience 2020

  Quote: ... including MAP2A/B (Genetex; 1:500 dilution), βIII-tubulin (Genetex ...
• Self-activation of Wnt signaling in pre-granulosa cells is required for ovarian folliculogenesis

  Okiko Habara, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-Amh (1:100; GTX129593, GeneTex), rabbit anti-FoxO3 (1:500 ...
• SARS-CoV-2 spike-glycoprotein processing at S1/S2 and S2’and shedding of the ACE2 viral receptor: roles of Furin and TMPRSS2 and implications for viral infectivity and cell-to-cell fusion

  Rachid Essalmani, et al., bioRxiv - Biochemistry 2021

  Quote: ... spike (mouse monoclonal GTX632604; 1:500; GeneTex) and ACE2 (goat polyclonal AF933 ...
• Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K⁺ channels

  Sharon R. Stevens, et al., bioRxiv - Neuroscience 2021

  Quote: ... and neuropilin-1 (GeneTex Cat# GTX16786, RRID:AB_422398), Kv3.1b (Alomone Labs Cat# APC-014 ...