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451 - 500 of 917 citations for 1 5 Bromo 1 2 Trimethylsilyl Ethoxy Methyl 1H Pyrrolo 2 3 B Pyridin 3 Yl Ethanone since 2020

• Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression

  Tommaso Montecchi, et al., bioRxiv - Cancer Biology 2023

  Quote: The surface expression of PD-1 was assessed by labeling transfected T cells with anti-PD-1 (Genetex) primary antibody and Alexa Fluor-647 anti-mouse secondary antibody (Thermo Fisher Scientific ...
• Protective Effects of Butyrate on Retinal Neovascularization in Preclinical Retinopathy of Prematurity Models

  Allston Oxenrider, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... GFAP (1:1000, Abacm Waltham, Boston, MA, USA) and RBPMS (1:500, Genetex, Alton Pkwy Irvine, CA USA). After immunoblotting ...
• Sox10 is required for systemic initiation of bone mineralization

  Stefani Gjorcheska, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Primary antibodies included anti-Na+/K+ ATPase (1:400, DSHB α5) and anti-Sox10 (1:500, Genetex GTX128374), used with AlexaFluor 647-conjugated goat anti-mouse and donkey anti-rabbit secondary antibodies (1:250 ...
• Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

  Mounir El-Maï, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-g-H2AX (1:1000, GeneTex, GTX127342); anti-p16 (F-12 ...
• Repression of MAPK/Erk signaling by Efnb2-Ephb4-Rasa1 is required for lymphatic valve formation

  Yaping Meng, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-Prox1 (1/200; GeneTex, GTX128354), chicken anti-GFP (1/200 ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti-GAPDH (GeneTex, GTX627408; 1:10000), mouse anti-Ku86 (Santa Cruz ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-GAPDH (GeneTex, GTX100118, 1:5000); and rabbit anti-alpha tubulin (Cell Signaling ...
• Autophagy receptor NDP52 alters DNA conformation to modulate RNA Polymerase II transcription

  Ália dos Santos, et al., bioRxiv - Biophysics 2022

  Quote: ... rabbit anti-NDP52 (1:200, Genetex GTX115378) antibodies were used ...
• Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

  Ryoji Amamoto, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit Iba1 (1:500, GeneTex, cat. #GTX100042), mouse Glutamine Synthetase (1:3000 ...
• The Exon Junction Complex Core Represses Caner-specific Mature mRNA Re-splicing: A Potential Key Role in Terminating Splicing

  Yuta Otani, et al., bioRxiv - Molecular Biology 2021

  Quote: ... RBM8A (1:1000; GeneTex, Irvine, CA, USA), and MAGOH (1:1000 ...
• Bi-allelic MCM10 mutations cause telomere shortening with immune dysfunction and cardiomyopathy

  Ryan M. Baxley, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse anti-GAPDH (GeneTex GTX627408; 1:5,000), mouse anti-<ι>α-Tubulin (Millipore T9026 ...
• Regulation of KHNYN antiviral activity by the extended di-KH domain and nucleo-cytoplasmic trafficking

  María José Lista, et al., bioRxiv - Microbiology 2021

  Quote: ... 1:5000 anti-HSP90 (Rabbit, GeneTex, GTX109753), 1:1000 anti-FLAG (DYKDDDDK ...
• The E3 ubiquitin ligase RNF216/TRIAD3 is a central regulator of the hypothalamic-pituitary-gonadal axis

  Arlene J. George, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-β-Actin (Genetex, 1:3,000) and were incubated overnight at 4°C ...
• OSCAR: a framework to identify and quantify cells in densely packed three-dimensional biological samples

  Mario Ledesma-Terrón, et al., bioRxiv - Systems Biology 2021

  Quote: ... rabbit anti-Sox2 (1:1000, GeneTex GTX124477), mouse anti-PCNA (1:100 ...
• Viral-mediated ubiquitination impacts interactions of host proteins with viral RNA and promotes viral RNA processing

  Christin Herrmann, et al., bioRxiv - Microbiology 2020

  Quote: ... RAD50 (GeneTex, Catalog#: GTX70228, WB 1:1000) and USP7 (Bethyl Laboratories ...
• Extracellular Matrix Dysfunction in Sorsby Patient-Derived Retinal Pigment Epithelium

  Abbi L. Engel, et al., bioRxiv - Cell Biology 2021

  Quote: ... TIMP3 (1:5000, GTX25939, GeneTex, Irvine, CA), and Vitronectin (1:1000 ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... mouse anti-GAPDH 1:10,000 (GeneTex, GTX28245), rabbit anti-GAPDH 1:10,000 (GeneTex ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit anti-GAPDH 1:10,000 (GeneTex, GTX100118), anti-pUL16 1:2000 (Carmichael and Wills ...
• Oncogene-induced cardiac neoplasia shares similar mechanisms with heart regeneration in zebrafish

  Catherine Pfefferli, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit Myl7 1:200 at (GTX128346, GeneTex), mouse anti-A4.1025 at (developed by H.M ...
• Chromosome length and gene density contribute to micronuclear membrane stability

  Anna E Mammel, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-CENPA (1:100; GTX13939, GeneTex), mouse or rabbit anti-H3K27ac (1:250 ...
• Visualizing cancer-originated acetate uptake through MCT1 in reactive astrocytes demarcates tumor border and extends survival in glioblastoma patients

  Hae Young Ko, et al., bioRxiv - Cancer Biology 2022

  Quote: ... goat anti-rabbit-HRP (GeneTex, 1:2000). Immunoreactive protein bands were visualized via enhanced chemiluminescence and scanned with a LAS-4000 system (GE Healthcare).
• Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation

  Alex F. Thompson, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-KIF22 1:500 (GeneTex #GTX112357), mouse anti-centrin 1:500 (Millipore Sigma #04-1624) ...
• A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods

  Maria Jose Lista, et al., bioRxiv - Microbiology 2022

  Quote: ... 1:5000 anti-HSP90 (Rabbit, GeneTex, GTX109753), 1:1000 anti- FLAG (DYKDDDDK ...
• Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections

  Michel Fries, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-POU3F1 rabbit (1:100, Genetex, GTX134063), anti-POU3F1 mouse (1:100 ...
• The mRNA cap 2’O methyltransferase CMTR1 regulates the expression of certain interferon-stimulated genes

  Graham D. Williams, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-GAPDH (GeneTex, GT239, 1:1000) mouse anti-STAT1 (BD ...
• Sequestration of LINE-1 in novel cytosolic bodies by MOV10 restricts retrotransposition

  Rajika Arora, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-DDX6 (1:2000, GTX102795 GeneTex), anti-rabbit IgG HRP-linked (1:10000 7074 ...
• Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity

  Beatriz Gomez Perez-Nievas, et al., bioRxiv - Neuroscience 2021

  Quote: ... MAP2 (Mouse IgG, #GTX8266, GeneTex, 1/200), and GFAP (Rabbit IgG ...
• Myostatin is a negative regulator of adult neurogenesis in zebrafish

  Vishnu Muraleedharan Saraswathy, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-PCNA (GeneTex, GTX124496, 1:500), mouse anti-HuC/D (Invitrogen ...
• Myostatin is a negative regulator of adult neurogenesis in zebrafish

  Vishnu Muraleedharan Saraswathy, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Sox2 (GeneTex, 124477, 1:250). Secondary antibodies (Invitrogen ...
• ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain of function

  Devesh C. Pant, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-β actin (1:2000; GeneTex) overnight at 4°C followed by HRP-conjugated secondary antibodies (ABclonal ...
• CRISPR metabolic screen identifies ATM and KEAP1 as targetable genetic vulnerabilities in solid tumors

  Haojian Li, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p53 (1:1000; GTX70214, GeneTex, CA, USA); Phospho-p53 (1:1000 ...
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... type 6a1 collagen (GTX109963, Genetex, 1:300), α-Smooth muscle actin (aSMA ...
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... type 6a1 collagen (GTX109963, Genetex, 1:3000), laminin B2 (sc-59980 ...
• Self-activation of Wnt signaling in pre-granulosa cells is required for ovarian folliculogenesis

  Okiko Habara, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-Amh (1:100; GTX129593, GeneTex), rabbit anti-FoxO3 (1:500 ...
• SARS-CoV-2 spike-glycoprotein processing at S1/S2 and S2’and shedding of the ACE2 viral receptor: roles of Furin and TMPRSS2 and implications for viral infectivity and cell-to-cell fusion

  Rachid Essalmani, et al., bioRxiv - Biochemistry 2021

  Quote: ... spike (mouse monoclonal GTX632604; 1:500; GeneTex) and ACE2 (goat polyclonal AF933 ...
• Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K⁺ channels

  Sharon R. Stevens, et al., bioRxiv - Neuroscience 2021

  Quote: ... and neuropilin-1 (GeneTex Cat# GTX16786, RRID:AB_422398), Kv3.1b (Alomone Labs Cat# APC-014 ...
• Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis

  Dennis Ma, et al., bioRxiv - Cancer Biology 2020

  Quote: ... diluted 1:100 (GeneTex Cat. No. GTX14082) and PI ...
• Modulation of Early Mitotic Inhibitor 1 (EMI1) Depletion on the Sensitivity of PARP Inhibitors in BRCA1 Mutated Triple-Negative Breast Cancer Cells

  Dina Moustafa, et al., bioRxiv - Cancer Biology 2020

  Quote: ... RAD51 (GeneTex, Cat. No. GTX70230 (1:500)) ...
• Rabaptin5 targets autophagy to damaged endosomes and SCVs by interaction with FIP200 and ATG16L1

  Valentina Millarte, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-MYC (GTX29106, GeneTEX, 1:5000) rabbit anti-mCherry (PA5-34974 ...
• Tumor protein D52 (TPD52) affects cancer cell metabolism by negatively regulating AMPK

  Yali Chen, et al., bioRxiv - Cell Biology 2021

  Quote: ... TPD52 (GTX115042, WB:1:400 dilution; GeneTex), Anti-His tag (sc8036 ...
• Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation

  Jaime Fabra-Beser, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-Pax6 (1:500, GeneTex, #GTX113241); mouse anti-Phospho Vimentin (1:500 ...
• The polybasic cleavage site in the SARS-CoV-2 spike modulates viral sensitivity to Type I IFN and IFITM2

  Helena Winstone, et al., bioRxiv - Immunology 2020

  Quote: ... 1:5000 HSP90 mouse (Genetex, Gt×109753), 1:50 HIV-1 p24Gag mouse (Chesebro ...
• Intrabody induced cell death by targeting the T. brucei cytoskeletal protein TbBILBO1

  Christine E. Broster Reix, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-HA (rabbit, GeneTex GTX115044, 1:1000) were incubated for 1h in a dark moist chamber ...
• Translational approach to social isolation during a global pandemic: Hippocampal somatic mutation

  Bomee Lee, et al., bioRxiv - Neuroscience 2023

  Quote: ... CRHR1 antibody (1:1000, GeneTex, goat, GRX88961), CRHR2 antibody (1:1000 ...
• CCT and Cullin1 regulate the TORC1 pathway to promote dendritic arborization in health and disease

  Erin N. Lottes, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-CCT5 (1:200 dilution, GeneTex), mouse anti-S6k (1:200 dilution ...
• SRC family kinase inhibition rescues molecular and behavioral phenotypes, but not protein interaction network dynamics, in a mouse model of Fragile X syndrome

  Vera Stamenkovic, et al., bioRxiv - Neuroscience 2023

  Quote: ... and β-actin (1:10,000, GTX109639, GeneTex). Primary antibodies were detected using species-specific horseradish peroxidase– conjugated secondary antibodies ...
• Genetic dissection of BDNF and TrkB expression in glial cells

  Changran Niu, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-ASPA (1:1500; GeneTex #GTX113389), chicken anti-GFP (1:2000 ...
• BMP7 promotes cardiomyocyte regeneration

  Chiara Bongiovanni, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Myl7 (1:300, GTX128346, RRID:AB_2885759, Genetex). Secondary antibodies conjugated to Alexa 488 ...
• Pharmacologic Targeting of PDIA1 Inhibits NLRP3 Inflammasome Assembly and Activation

  Jessica D. Rosarda, et al., bioRxiv - Cell Biology 2023

  Quote: ... IL-1β (1:1000, GeneTex cat. GTX74034), PDIA1 (1:1000 ...
• Herpes simplex virus 1 protein pUL21 stimulates cellular ceramide transport by activating CERT

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2022

  Quote: ... mouse anti-GAPDH 1:10,000 (GeneTex, GTX28245), mouse anti-Myc 1:4000 (Millipore ...