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5001 - 5050 of 10000+ citations for 6 THIOPHEN 2 YL 1H INDAZOLE since 2019

• An oxadiazole-based compound potentiates anti-tuberculosis treatment by increasing host resistance via zinc poisoning

  Alexandra Maure, et al., bioRxiv - Microbiology 2023

  Quote: ... and 2 mM L-glutamine (Gibco) with macrophage colony stimulating factor (M-CSF ...
• Synaptic alterations associated with disrupted sensory encoding in a mouse model of tauopathy

  Soraya Meftah, et al., bioRxiv - Neuroscience 2023

  Quote: ... SeeBlue Plus 2 Prestained Standard (Invitrogen) was used as a molecular weight ladder.
• A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models

  Joseph M Hoolachan, et al., bioRxiv - Pathology 2023

  Quote: ... 2% horse serum (HS) (#26050070, Gibco), 1% penicillin-streptomycin (10,000 U/ml ...
• Recording morphogen signals reveals origins of gastruloid symmetry breaking

  Harold M. McNamara, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1:100 N-2 (Gibco, 17502048), 1:50 B-27 (Gibco ...
• Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control

  Barun Mahata, et al., bioRxiv - Bioengineering 2023

  Quote: ... 55 mM 2-Mercaptoethanol (Gibco, 21985023), 4 mM N-acetyl-L-cysteine (Thermo Fisher Scientific ...
• A transient protein folding response targets aggregation in the early phase of TDP-43-mediated disease

  Rebecca San Gil, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2 mM L-glutamine (Gibco 25030081), and 1% v/v penicillin/streptomycin ...
• Radical fringe facilitates NOTCH1 and JAG1 cis interactions to sustain Hematopoietic stem cell fate

  Roshana Thambyrajah, et al., bioRxiv - Developmental Biology 2023

  Quote: ... fixed in 2% Paraformaldehyde (Thermo Fisher) for 12 minutes ...
• Functional genomics identifies extension of complex N-glycans as a mechanism to evade lysis by natural killer cells

  Xiaoxuan Zhuang, et al., bioRxiv - Immunology 2023

  Quote: ... and 2 mM L-Glutamine (Gibco). To block the glycosylation pathway ...
• Respiratory Complex I Regulates Dendritic Cell Maturation in Explant Model of Human Tumor Immune Microenvironment

  Rita Turpin, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 2 mM L-Glutamine (Gibco). PDECs were cultured in MammoCult (StemCell technologies) ...
• Respiratory Complex I Regulates Dendritic Cell Maturation in Explant Model of Human Tumor Immune Microenvironment

  Rita Turpin, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 2 mM L-Glutamine (Gibco) with added 100ng/mL Human GM-CSF (Miltenyi Biotec) ...
• Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

  Quyen B. Do, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2 mM L-glutamine (Life Technologies), 2% B27 ...
• High-resolution spatial multi-omics reveals cell-type specific nuclear compartments

  Yodai Takei, et al., bioRxiv - Genomics 2023

  Quote: ... 55 μM 2-mercaptoethanol (Gibco 21985023), 1× penicillin and streptomycin (Gibco 15140122 ...
• Data-driven discovery of innate immunomodulators via machine learning-guided high throughput screening

  Yifeng Tang, et al., bioRxiv - Immunology 2023

  Quote: ... 2 mM L-glutamine (Life Technologies), 1% antibiotic-antimycotic (Life Technologies) ...
• Epigenomic Analyses Identify FOXM1 As a Key Regulator of Anti-Tumor Immune Response in Esophageal Adenocarcinoma

  Benjamin Ziman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 2% penicillin-streptomycin sulfate (Gibco, #10378016), and 1X Primocin (InvivoGen ...
• A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia

  Lalit Kaurani, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2 mM Glutamax (Invitrogen Life Technologies), and 0.055 mM beta-mercaptoethanol (Thermo Fisher Scientific) ...
• Host cell glycosylation selects for infection with CCR5- versus CXCR4-tropic HIV-1

  Hannah L. Itell, et al., bioRxiv - Microbiology 2023

  Quote: ... 2 mM L-glutamine (Gibco #25030081), 1X antibiotic-antimycotic (Gibco #15240062 ...
• A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia

  Lalit Kaurani, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2 mM Glutamax (Invitrogen Life Technologies), and 0.055 mM beta-mercaptoethanol (Thermo Fisher Scientific) ...
• C1q Enables Influenza HA Stem Binding Antibodies to Block Viral Attachment and Broadens the Antibody Escape Repertoire

  Ivan Kosik, et al., bioRxiv - Microbiology 2023

  Quote: ... and 2 mL OPTIMEM media (Gibco). We combined 32 μg of pCAGGS-S-Covid19 (SFL ...
• Prolonging the Delivery of Influenza Virus Vaccine Improves the Quantity and Quality of the Induced Immune Responses in Mice

  M. Beukema, et al., bioRxiv - Immunology 2023

  Quote: ... and 50 µM 2-mercaptoethanol (Invitrogen) Lymph nodes and spleens were used for flow cytometry and Enzyme-Linked Immunosorbent Spot (ELISPOT) ...
• Dual-color GRAB sensors for monitoring spatiotemporal serotonin release in vivo

  Fei Deng, et al., bioRxiv - Neuroscience 2023

  Quote: ... containing 2% B-27 supplement (GIBCO), 1% GlutaMax (GIBCO) ...
• Generating human neural diversity with a multiplexed morphogen screen in organoids

  Neal D. Amin, et al., bioRxiv - Neuroscience 2023

  Quote: ... N-2 supplement (Life Technologies, 17502048) and Penicillin-Streptomycin (1:100 ...
• Multi-omics analyses identify transcription factor interplay in corneal epithelial fate determination and disease

  Jos GA Smits, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 2 mM Glutamine (Gibco, Life Technologies) and 100 U/ml Penicillin/Streptomicin (Gibco ...
• Polycomb sustains promoters in a deep OFF-state by limiting PIC formation to counteract transcription

  Aleksander T. Szczurek, et al., bioRxiv - Cell Biology 2023

  Quote: ... 2 mM L-glutamine (Life Technologies), 1x non-essential amino acids (Life Technologies) ...
• ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats

  Giacomo Grillo, et al., bioRxiv - Genomics 2023

  Quote: ... 100nM 2-mercaptoethanol (Thermo Fisher Scientific), 3µM CHIR99201 ...
• Modeling of lung-liver interaction during infection in a human microfluidic organ-on-a-chip

  Susanne Reinhold, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 2% FBS (Thermofisher Scientific, USA). After the airlift ...
• Cystic fibrosis transmembrane conductance regulator (CFTR) downregulates the excitability of deep pyramidal neurons in the rodent cortex

  Zongyue Cheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... with 2% B-27 supplement (Gibco), 1% GlutaMax (Gibco) ...
• Regulation of BCR-mediated Ca²⁺ mobilization by MIZ1-TIMBIM4 safeguards IgG1⁺ GC B cell positive selection

  Lingling Zhang, et al., bioRxiv - Immunology 2023

  Quote: ... 5-ethynyl-2’-deoxyuridine (EdU, Invitrogen) was dissolved in sterile PBS (5 mg/mL) ...
• Regulation of BCR-mediated Ca²⁺ mobilization by MIZ1-TIMBIM4 safeguards IgG1⁺ GC B cell positive selection

  Lingling Zhang, et al., bioRxiv - Immunology 2023

  Quote: ... 2% Fetal bovine serum (FBS, Gibco) in PBS for 30 min at RT ...
• Optimization of RNA Pepper sensors for the detection of arbitrary RNA targets

  Anli Tang, et al., bioRxiv - Biochemistry 2023

  Quote: ... 0.1mM 2-Mercaptoethanol (GIBCO, 21985-023) in DMEM (Sigma ...
• Multi-omics analyses identify transcription factor interplay in corneal epithelial fate determination and disease

  Jos GA Smits, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 2 mM Glutamine (Gibco, Life Technologies) and 100 U/ml Penicillin/Streptomicin (Gibco ...
• CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer

  Karin Gustafsson, et al., bioRxiv - Immunology 2023

  Quote: ... with 2% (v/v) FBS (Gibco) and 0.25μg 7-Aminoactinomycin D (7AAD ...
• CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer

  Karin Gustafsson, et al., bioRxiv - Immunology 2023

  Quote: ... with 2% (v/v) FBS (Gibco) and 1 μg/ml 4′,6-diamidino-2-phenylindole (DAPI ...
• Bordetella Filamentous hemagglutinin (FhaB) and Adenylyl cyclase toxin (ACT) interactions on the bacterial surface are consistent with FhaB-mediated delivery of ACT to phagocytic cells

  Zachary M Nash, et al., bioRxiv - Microbiology 2023

  Quote: ... and 2 mM L-glutamine (Gibco). J774A.1 cells additionally were supplemented with 1% MEM Non-Essential Amino Acids (Gibco) ...
• Diseased human pancreas and liver microphysiological system for preclinical diabetes research

  Sophie Rigal, et al., bioRxiv - Cell Biology 2023

  Quote: ... 2 mM GlutaMax (35050-061, Gibco), 50 µM hydrocortisone hemisuccinate (H4881 ...
• Suppression of autoimmune arthritis and neuroinflammation via an amino acid-conjugated butyrate prodrug with enhanced oral bioavailability

  Shijie Cao, et al., bioRxiv - Bioengineering 2023

  Quote: ... 2 mM l-glutamine (Life Technologies), 1% antibiotic-antimycotic (Life Technologies) ...
• Calculation of ATP production rates using the Seahorse XF Analyzer

  Brandon R. Desousa, et al., bioRxiv - Biochemistry 2023

  Quote: ... 2 mM GlutaMAX (Thermo Fisher Scientific), 100 U/ml penicillin ...
• MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size

  Michael J. Lafferty, et al., bioRxiv - Genetics 2023

  Quote: ... 2% B27 (Life Technologies 17504-044), 1x glutamax (Life Technologies 35050061) ...
• Shotgun proteomic analysis of the caterpillar Lonomia obliqua (Lepitoptera, Saturniidae) hemolymph and effects in rat hippocampal neurons culture

  Silviane Maggi, et al., bioRxiv - Biochemistry 2023

  Quote: ... and 2% B27 supplement (Gibco, USA), to reduce glial cell proliferation (Brewer et al. ...
• Excess PrP^C inhibits muscle cell differentiation via miRNA-enhanced liquid–liquid phase separation implicated in myopathy

  Jing Tao, et al., bioRxiv - Biochemistry 2023

  Quote: ... supplemented with 2% horse serum (Gibco) and 1% penicillin-streptomycin.
• Single-nucleus sequencing reveals enriched expression of genetic risk factors in Extratelencephalic Neurons sensitive to degeneration in ALS

  Francesco Limone, et al., bioRxiv - Neuroscience 2023

  Quote: ... ITSG-X 2% v/v (ThermoFisher), L-ascorbic acid 2-Phosphate (64 ug/ml ...
• Genetically-encoded photosensitizers enable light-controlled polymerization on living neuronal membranes

  Anqi Zhang, et al., bioRxiv - Bioengineering 2022

  Quote: ... and 2 mM Glutamax (Gibco, 35050061), fixed in 4% paraformaldehyde (PFA ...
• ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis

  Alexandre Jourdon, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2% B27 without vitamin A (Invitrogen), 1:100 NEAA ...
• A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective

  Han Wee Ong, et al., bioRxiv - Cell Biology 2023

  Quote: ... and N-2 (1%, Thermo Fisher). Differentiation media was supplemented as needed over the 16-day period.38
• Light and electron microscopy continuum-resolution imaging of 3D cell cultures

  Edoardo D’Imprima, et al., bioRxiv - Cell Biology 2022

  Quote: ... FM4-64 2 µM (Thermo Fisher Scientific ...
• 3D Co-culture Model on the Role of Vimentin in Notch Signaling and Vascularization

  Khalil Dayekh, Kibret Mequanint, bioRxiv - Bioengineering 2023

  Quote: ... 2 µL lipofectamine RNAiMAX (Life Technologies) was added and mixed gently and then transferred to a plate well ...
• Species-specific LUBAC-mediated M1 ubiquitination regulates necroptosis by segregating the cellular distribution and fate of activated MLKL

  Nadine Weinelt, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1x N-2 (Thermo Fisher Scientific), 2,5 mM N-acetylcysteine (MilliporeSigma ...
• MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, and enhances the viral infection of Burkitt lymphoma cells

  Ester Molina, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 50 μM 2-mercaptoethanol (Gibco) and transduced with control pMX-Orange or pMX-MYC-Orange retrovirus ...
• Filopodial protrusion driven by density-dependent Ena-TOCA-1 interactions

  Thomas C. A. Blake, et al., bioRxiv - Cell Biology 2023

  Quote: ... with 2 mM GlutaMAX (Gibco, 35050038), 10% FBS ...
• Calcium flux through ER-TGN contact sites facilitates cargo export

  Bulat R. Ramazanov, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 2 mM glutamine (Life Technologies) supplemented with 10 % FBS was used ...
• Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury

  Tony Marchand, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 2 mg.ml-1 dispase (Gibco)) on a rotator ...