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51 - 100 of 4801 citations for 6 Methyl 2 7 naphthyridin 1 2H one since 2019

• Subcellular localization of mutant P23H rhodopsin in an RFP fusion knockin mouse model of retinitis pigmentosa

  Michael A. Robichaux, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-centrin 2 (Proteintech, 15877-1-AP); rabbit anti-BiP (Abcam ...
• In vivo CGG repeat RNA binding protein capture identifies RAN translation modifiers and suppressors of repeat toxicity

  Indranil Malik, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1:1000 SRSF1 (Rabbit, Proteintech 12929-2-AP), 1:1000 SRSF2 (Rabbit ...
• Effects of protoscoleces excretory-secretory products of Echinococcus granulosus on hepatocyte growth, function, and glucose metabolism

  Guangyi Luo, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-GLUT-2 (1:1000, Proteintech, China), rabbit anti-GS (1:1000 ...
• Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins

  John Fehilly, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-GFP (Proteintech, 50430-2-AP, 1:4000), anti-pan-14-3-3 (B-8 ...
• Subcellular proteome of radial glia reveals non-muscle myosins control basal endfeet to mediate interneuron organization

  Brooke R D’Arcy, et al., bioRxiv - Neuroscience 2022

  Quote: ... Anti-PSEM2 (ProteinTech, 12937-2-AP, 1:100) Mouse ...
• PXN/Paxillin Phase Separation Promotes Focal Adhesion Assembly and Integrin Signaling

  Peigang Liang, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Kindlin-2 (Proteintech; 11453-1-AP), mouse anti-α1 Na+/K+ ATPase (Abcam ...
• An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation

  Kai He, et al., bioRxiv - Cell Biology 2023

  Quote: ... GFP (50430-2-AP, Proteintech, dilution 1:1000), Flag (8146 ...
• Propagation of neuronal micronuclei regulates microglial states

  Sarasa Yano, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Rab35 (11329-2-AP, Proteintech, 1:1000), anti-Tubulin (DM1A ...
• PXN/Paxillin Phase Separation Promotes Focal Adhesion Assembly and Integrin Signaling

  Peigang Liang, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Kindlin-2 (Proteintech; 11453-1-AP), rabbit anti-LIMD1 (Proteintech ...
• An ULK1/2-PXN mechanotransduction complex suppresses breast cancer cell migration

  Peigang Liang, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Kindlin-2 (Proteintech; 11453-1-AP), rabbit anti-HIC-5 (Proteintech ...
• Mapping RNA-Protein Interactions with Subcellular Resolution Using Colocalization CLIP

  Soon Yi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... TIA1 (Proteintech, cat. #12133-2-AP, 1:500), GAPDH (Cell Signallng ...
• TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

  Yi Zeng, et al., bioRxiv - Neuroscience 2024

  Quote: ... TDP-43 (1:1,500, Proteintech 10782-2-AP), ELP1 (1:500 ...
• Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals

  Shuai-dong Chen, et al., bioRxiv - Immunology 2023

  Quote: ... and Igfbp3 (10189-2-AP, Proteintech, 1:100) were performed for to assess the angiogenesis and fibroblast migration respectively ...
• The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in T cells

  Francesca Finetti, et al., bioRxiv - Immunology 2020

  Quote: ... Postnuclear supernatants (2 mg/sample) were immunoprecipitated for 2 h using 2 μg of rabbit anti-IFT20 antibody (#13615-1-AP, Proteintech), anti-ATG16L1 antibody (#8089S ...
• The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

  Elisa Avolio, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Transmembrane Serine Protease 2 (TMPRSS2 - Proteintech 14437-1-AP, 1:100); anti-Neural/Glial antigen 2 (NG2 - Millipore AB5320 ...
• Small molecule v-ATPase inhibitor Etidronate lowers levels of ALS protein ataxin-2

  Garam Kim, et al., bioRxiv - Neuroscience 2021

  Quote: ... primary antibodies against ataxin-2 (1:100; Rabbit; ProteinTech 21776-1-AP) and house-keeping protein GAPDH (1:500 ...
• Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

  Kizito-Tshitoko Tshilenge, et al., bioRxiv - Neuroscience 2022

  Quote: ... Primary mouse monoclonal antibody Septin-2 (Proteintech, 60075-1-Ig, 1:20,000), rabbit polyclonal antibody Septin-9 (Proteintech ...
• Connexin Hemichannels with Prostaglandin Release in Anabolic Function of Bone to Mechanical Loading

  Dezhi Zhao, et al., bioRxiv - Physiology 2021

  Quote: ... anti-COX-2 (12375-1-AP, 1:200, Proteintech, Rosemont, IL, USA) or an anti-β-catenin antibody (ab16051 ...
• Disruption of the Blood-Brain Barrier in 22q11.2 Deletion Syndrome

  Alexis M. Crockett, et al., bioRxiv - Neuroscience 2019

  Quote: ... Antibodies were diluted in 3% normal donkey serum (monoclonal mouse anti-mouse GFAP 1:2000, Sigma G-A-5; polyclonal rabbit anti-human IL-6 1:50, Proteintech), and incubated overnight at 4°C ...
• The versatility of Ascorbate Peroxidase-aided mapping uncovers insights of the nuclear lamina interactions and function

  Joseph R. Tran, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-SRSF1 (1:2500, ProteinTech, #12929-2-AP).
• Sequestration of TDP-43^216-414 aggregates by cytoplasmic expression of the proSAAS chaperone

  Juan R. Peinado, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-TDP-43 (Proteintech 10782-2-AP, 1:1000), or anti-PGK1 (Invitrogen 459250 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-G3BP1 (Proteintech 13057-2-AP, 1:500), goat anti-Importin β-1 (Santa Cruz sc-1863 ...
• Substrate-induced clustering activates Trim-Away of pathogens and proteins

  Jingwei Zeng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit anti-GFP (Proteintech 50430-2-AP; 1:1000), rabbit anti-GFP (Abcam ...
• Substrate-induced clustering activates Trim-Away of pathogens and proteins

  Jingwei Zeng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit anti-GFP (Proteintech 50430-2-AP; 1:1000), mouse anti-CyPB (k3E2 ...
• Multiple Ciliary Localization Signals Control INPP5E Ciliary Targeting

  Dario Cilleros-Rodriguez, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-EGFP (Proteintech, 50430-2-AP, WB: 1:1000), anti-ARL13B (Proteintech ...
• A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia

  Feng Long, et al., bioRxiv - Genomics 2020

  Quote: ... anti-MYC (1:10000, 60003-2-Ig, Proteintech Group), anti-SMAD1 (1:1000 ...
• A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia

  Feng Long, et al., bioRxiv - Genomics 2020

  Quote: ... anti-HA (1:10000, 66006-2-Ig, Proteintech Group), anti-MYC (1:10000 ...
• Lineage transcription factors co-regulate subtype-specific genes providing a roadmap for systematic identification of small cell lung cancer vulnerabilities

  Karine Pozo, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-PROX1 (1:2000; Proteintech 11067-2-AP), rabbit anti-NFIB (1:4000 ...
• The novel chaperone protein SRCP1 reduces insoluble SOD1 protein in vivo without extending ALS mouse lifespan

  Ian W. Luecke, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-TDP43 (Proteintech 10782-2-AP, 1:1000), rat anti-HSP70 (Cell Signaling 4873S ...
• TDP-43 stabilizes transcripts encoding stress granule protein G3BP1: potential relevance to ALS/FTD

  Hadjara Sidibé, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-G3BP1 (1:4500, Proteintech, 13057-2-AP), and guinea pig anti-FluoroGold (1:750 ...
• Neuronal activity regulates Matrin 3 levels and function in a calcium-dependent manner through calpain cleavage and calmodulin binding

  Ahmed M. Malik, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-TDP43 (1:5000, Proteintech 10782-2-AP); rabbit anti-phospho-PKA substrate (1:1000 ...
• Cortical hyperexcitability drives dying forward ALS symptoms and pathology in mice

  Mouna Haidar, et al., bioRxiv - Neuroscience 2021

  Quote: ... and TDP-43 (Rabbit, 1:1000,10782-2-AP, Proteintech). Blots were washed three times in TBST the following day in 10 minute intervals and incubated with 800CW secondary antibody (1:10,000 ...
• Cyclin G2 inhibits oral squamous cell carcinoma growth and metastasis by binding to insulin-like growth factor binding protein 3 and regulating the FAK-SRC-STAT signaling pathway

  Danning Wang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MMP9 (1:500, 10375-2-AP, Proteintech, ID, USA); β-actin (1:1000 ...
• Deficiency of intellectual disability-related gene Brpf1 reduced inhibitory neurotransmission and Map2k7 expression in GABAergic interneurons

  Jingli Cao, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-GFP (Proteintech, 50430-2-AP, 1:500), mouse anti-GABA (Sigma ...
• The versatility of Ascorbate Peroxidase-aided mapping uncovers insights of the nuclear lamina interactions and function

  Joseph R. Tran, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-SRSF1 (1:2500, ProteinTech, #12929-2-AP), rabbit anti-SRSF7 (1:2500 ...
• Chaperones Hsc70 and Hsp70 Play Distinct Roles in Bocaparvovirus Minute Virus of Canines Infection

  Jianhui Guo, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-ubiquitin (10201-2-AP; Proteintech; WB: 1:500); anti-NS1 (WB ...
• Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans

  Qian Zhao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-NRBP1/2 antibody (21549-1-AP, Proteintech Europe), Phospho-Histone γH2AX antibody (Ser139 ...
• Hepatocyte Differentiation From Mouse Liver Ductal Organoids By Transducing Four Liver-Specific Transcription Factors

  Katsuhiro Tomofuji, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-PROX1 (Proteintech, 11067-2-AP, 1:1000), rabbit anti-FOXA1 (Abcam ...
• C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress

  ME Cicardi, et al., bioRxiv - Neuroscience 2023

  Quote: ... GFP (WB dilution 1:1,000 Proteintech #50430-2-AP), NeuN (IF dilution 1:2,000 Novus Biologicals #NBP1-92693) ...
• hnRNP R is a regulator of stress granule formation

  Changhe Ji, bioRxiv - Neuroscience 2022

  Quote: ... primary antibody g3bp1(1:500, Proteintech,13057-2-AP), TIAR (1:500 ...
• Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

  Ferrol I. Rome, et al., bioRxiv - Physiology 2022

  Quote: ... glycogen synthase 2 (GS; Proteintech, 22371-1-AP; RRID:AB_2879091), mitochondrial encoded cytochrome c oxidase II (MT-CO2 ...
• Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy

  Kristen N. Haggerty, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-centrin-2 (Proteintech Cat# 15877-1-AP, RRID:AB_2077383), anti-STX3 (Millipore Cat# MAB2258 ...
• GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

  Liang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-GFP (1:4000, 50430-2-AP, Proteintech), mouse anti-MT-CO1 (1:2000 ...
• Dysregulated actin dynamics and cofilin correlate with TDP-43 pathology in sporadic amyotrophic lateral sclerosis

  Cyril Jones Jagaraj, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-TDP-43 (Proteintech, #10782-2-AP, 1:1000), anti-β-actin clone C4 (Merck ...
• Biallelic Variants in MAD2L1BP (p31^comet) Cause Female Infertility Characterized by Oocyte Maturation Arrest

  Lingli Huang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and Myc (1:5000, Proteintech, Cat #60003-2-Ig). Beta-actin (1:10000 ...
• Wnt5a-Ror2 signaling activates p62-Nrf2 axis in reactive astrocytes after brain injury

  Mitsuharu Endo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-Keap1 (Proteintech, 10503-2-AP, 1:1000), rabbit anti-NBR1 (Cell Signaling Technology ...
• Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins

  M. Alejandra Zeballos C., et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit anti-ubiquitin (1:200, Proteintech, 10201-2-AP), chicken anti-NeuN (1:500 ...
• Recruitment of FBXO22 for Targeted Degradation of NSD2

  David Y. Nie, et al., bioRxiv - Biochemistry 2023

  Quote: ... SKP1 (1:1000 dilution; Proteintech 10990-2-AP; RRID:AB_2187492), CUL1 (1:1000 dilution ...
• The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male mice

  Tegan S. Horan, et al., bioRxiv - Genetics 2023

  Quote: ... RUVBL1 (rabbit) pAb 1:1000 (Proteintech 10210-2-AP); and ADAD2 (rabbit ...
• TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves

  Matthew Grove, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-IDI1 (Proteintech, #11166-2-AP; 1:1000). Control whole rabbit IgG for immunoprecipitations was from Jackson Laboratories (011-000-003 ...