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4401 - 4450 of 5255 citations for 6 Methylimidazo 1 2 a pyridine HCl since 2019

• Hedgehog signaling is non-cell autonomously activated in the cystic kidney of Arl13b mutant mice

  Chia-Ling Hsieh, et al., bioRxiv - Genetics 2022

  Quote: ... Blots were probed overnight at 4°C with the following primary antibodies: rabbit anti-vimentin at 1:2000 (Proteintech Group Inc, 10366-1-AP), rabbit anti-collagen I at 1:2000 (Proteintech Group Inc ...
• Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase

  Hudson W. Coates, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Immunoblotting was performed using the following antibodies: rabbit polyclonal anti-SM(SQLE) (Proteintech 12544-1-AP; 1:2,500 at 4 °C for 16 h), rabbit polyclonal anti-HIF1α (Proteintech 20960-1-AP ...
• Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

  Ruilin Tian, et al., bioRxiv - Genomics 2021

  Quote: ... Primary antibodies used for immunofluorescence in this study were as follows: rabbit anti-PSAP antibody (1:50 dilution; Proteintech; Cat. No. 10801-1-AP), mouse anti-LAMP2 antibody (1:100 dilution ...
• Reduced methionine synthase (Mtr) expression creates a functional vitamin B12 deficiency that leads to uracil accumulation in mouse mitochondrial DNA

  Katarina E. Heyden, et al., bioRxiv - Biochemistry 2022

  Quote: ... Membranes were then incubated for 1 hour with 1:2000 primary antibody (α-SHMT2 and GAPDH, Cell Signaling #33443S and #14C10; α-MTR, ProteinTech #25896) in 5% bovine serum albumin (BSA ...
• Chemical and genetic screens identify new regulators of tetracycline-inducible gene expression system in mammalian cells

  Valeria Colicchia, et al., bioRxiv - Molecular Biology 2022

  Quote: ... blocked in 3%BSA containing 0.1% Tween20 in PBS for 30 min and incubated over-night with antibodies against PR repeats (Proteintech, 23979-1-AP; 1:500) and ATXN2 (BD Biosciences ...
• Genetic deficiency of ribosomal rescue factor HBS1L causes retinal dystrophy associated with Pelota and EDF1 depletion

  Shiyu Luo, et al., bioRxiv - Genetics 2023

  Quote: ... Immunofluorescence was performed by standard protocol using rabbit anti-HBS1L polyclonal antibody (10359-1-AP, 1:50 dilution, Proteintech Group Inc., Chicago, IL, USA) and rabbit anti-PELO polyclonal antibody (10582-1-AP ...
• The Oncoprotein BCL6 Enables Cancer Cells to Evade Genotoxic Stress

  Yanan Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and anti-IFNAR1 (1;1000, Proteintech Cat# 13083-1-AP, RRID:AB_2122626). The immunoblots are representative of three independent experiments.
• Phospholipases D1 and D2 regulate cell cycling in primary prostate cancer cells and are differentially associated with the nuclear matrix

  Amanda R Noble, et al., bioRxiv - Cancer Biology 2021

  Quote: ... a rabbit polyclonal anti-Rictor antibody (Proteintech, 27248-1-AP) and a mouse monoclonal anti-mTOR antibody (Proteintech ...
• Phospholipases D1 and D2 regulate cell cycling in primary prostate cancer cells and are differentially associated with the nuclear matrix

  Amanda R Noble, et al., bioRxiv - Cancer Biology 2021

  Quote: ... a rabbit polyclonal anti-Raptor antibody (Proteintech, 20984-1-AP), a rabbit polyclonal anti-Rictor antibody (Proteintech ...
• METTL9 regulates N1-histidine methylation of zinc transporters to promote tumor growth

  Mengyue Lv, et al., bioRxiv - Cancer Biology 2021

  Quote: ... the membranes was incubated with secondary antibody (1:5000, ProteinTech) for 40 minutes and washed three times with TBST ...
• RTEL1 Influences the Abundance and Localization of TERRA RNA

  Fiorella Ghisays, et al., bioRxiv - Molecular Biology 2020

  Quote: ... GAPDH (Santacruz, sc_32233) and RNAse H1 (Proteintech 15606-1-AP).
• Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone

  Antonia Wiegering, et al., bioRxiv - Cell Biology 2020

  Quote: ... Sstr3 (#20696-1-AP; Proteintech and #PA3-207; Pierce Biotechnology), acetylated α-tubulin (#sc-23950 ...
• Loss of PKCα increases arterial medial calcification in a uremic mouse model of chronic kidney disease

  Samantha J Borland, et al., bioRxiv - Cell Biology 2020

  Quote: VSMC lysates were analyzed for PKCα (Proteintech 21991-1-AP), phosphorylated MARK2 ...
• Downregulation of miR-17-92 cluster by PERK fine-tunes unfolded protein response mediated apoptosis

  Danielle E. Read, et al., bioRxiv - Cell Biology 2020

  Quote: ... immunoprecipitation was conducted with anti-ATF4 antibody (Proteintech_Cat# 60035-1), anti-Nrf2 antibodies (Epitomocs_Cat# 2178-1) ...
• The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods

  Zhe Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... or rabbit anti-P62 (1:200, #18420, Proteintech, Wuhan, China) solution at 4 °C overnight ...
• Skap2 Regulates Atherosclerosis through Macrophage Polarization and Efferocytosis

  Danielle Hyatt, et al., bioRxiv - Cell Biology 2019

  Quote: ... and β-actin (66009-1-Ig) were obtained from Proteintech Group ...
• Inhibitory effects of Akt on neuronal FoxO4 activation after subarachnoid hemorrhage in vivo and in vitro

  Min Qi, et al., bioRxiv - Neuroscience 2020

  Quote: ... or anti-FoxO4 (Proteintech Group, Chicago, IL, USA; 1:2000) antibody overnight at 4°C ...
• An effective, safe and cost-effective cell-based chimeric vaccine against SARS-CoV2

  Zhenguo Cheng, et al., bioRxiv - Immunology 2020

  Quote: ... mouse anti-GAPDH mAb (monoclonal antibody) (ProteinTech, 60004-1-Ig), mouse anti-his tag mAb (Abmart ...
• CFIm25 regulates human stem cell function independently of its role in mRNA alternative polyadenylation

  Yi Ran, et al., bioRxiv - Molecular Biology 2021

  Quote: ... CFIm25 (10322-1-AP, Proteintech or sc-81109, Santa Cruz), REX1 (MA5-38664 ...
• Graded spikes differentially signal neurotransmitter input in cerebrospinal fluid contacting neurons of the mouse spinal cord

  Emily Johnson, et al., bioRxiv - Neuroscience 2022

  Quote: ... Sections were incubated with anti-PKD2L1 (1:500, rabbit, Proteintech) and anti-GFP (1:1000 ...
• Locus specific epigenetic modalities of random allelic expression imbalance

  Lucile Marion-Poll, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Primary antibodies against BAG3 (rabbit polyclonal, 10599-1-AP, Proteintech) and GAPDH (mouse monoclonal ...
• Methyltransferase-like 3 modulates severe acute respiratory syndrome coronavirus-2 RNA N6-methyladenosine modification and replication

  Xueyan Zhang, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit monoclonal anti-METTL3 (cat. no. 15073-1-AP; Proteintech), anti-METTL3 (cat ...
• TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV

  Roy Matkovic, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-SUPT6H (For WB and IP: 23073-1-AP, Proteintech) 1/1000 ...
• Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance anti-HIV activity in vitro

  Hanyu Pan, et al., bioRxiv - Bioengineering 2022

  Quote: ... rabbit anti-β-actin (1: 2500 dilution) (Proteintech, Wuhan, China), goat-anti-rabbit-secondary antibodies (1 ...
• mDia2 formin selectively interacts with catenins and not E-cadherin to regulate Adherens Junction formation

  Yuqi Zhang, et al., bioRxiv - Cell Biology 2019

  Quote: ... and incubated with antibodies against 1:100 β-catenin (Proteintech) and 1:100 E-cadherin (Cell Signaling) ...
• Molecular correlates of topiramate and GRIK1 rs2832407 genotype in pluripotent stem cell-derived neural cultures

  Richard Lieberman, et al., bioRxiv - Neuroscience 2019

  Quote: ... rabbit anti-TBR1 (a forebrain glutamatergic neuromarker; 1:1000, ProteinTech Group ...
• Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans

  Naomi Shomer, et al., bioRxiv - Genetics 2019

  Quote: ... Immunoprecipitation was performed using MED15 antibody (ProteinTech, 11566-1-AP). Crosslinking was then reversed by overnight incubation at 65°C and DNA purified using QIAquick PCR purification column (Qiagen ...
• Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

  I. Urrutia-Irazabal, et al., bioRxiv - Biochemistry 2021

  Quote: ... or a monoclonal anti-myc antibody (Proteintech; 67447-1-Ig). In the latter experiments ...
• Synaptic RTP801 Contributes to Motor Learning Dysfunction in Huntington’s Disease

  Núria Martín-Flores, et al., bioRxiv - Neuroscience 2020

  Quote: ... and rabbit polyclonal against RTP801 (1:150, Proteintech Group Inc.). AlexaFlour Phalloidin 568 (1:1000 ...
• Metabolic Reprogramming from Glycolysis to Fatty Acid Uptake and beta-Oxidation in Platinum-Resistant Cancer Cells

  Junjie Li, et al., bioRxiv - Cancer Biology 2021

  Quote: ... membranes were incubated with primary antibodies (CPT1a (1:1000) (Proteintech) and GapDH (1:2000 ...
• Statins attenuate antiviral IFN-β and ISG expression via inhibiting IRF3/JAK/STAT signaling in poly(I:C)-treated hyperlipidemic mice and macrophages

  Atsushi Koike, Kaito Tsujinaka, Ko Fujimori, bioRxiv - Biochemistry 2020

  Quote: ... and anti-STAT1 (66545-1-Ig; Proteintech, Rosemont, IL, USA). Anti-β-actin antibody (A2228 ...
• The RNA helicases DDX5 and DDX17 facilitate neural differentiation of human pluripotent stem cells NTERA2

  Praewa Suthapot, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-GAPDH conjugated peroxidase (Proteintech, HRP-60004, 1:30,000 dilution), goat anti-rabbit IgG conjugated peroxidase (Cell Signaling ...
• Glutamine deprivation triggers NAGK-dependent hexosamine salvage

  Sydney L. Campbell, et al., bioRxiv - Cancer Biology 2021

  Quote: ... The primary antibodies used were NAGK (Proteintech, 15051-1-AP), AKT phosphoS473 (Cell Signaling Technology ...
• Integrative Epigenomic and High-Throughput Functional Enhancer Profiling Reveals Determinants of Enhancer Heterogeneity in Gastric Cancer

  Taotao Sheng, et al., bioRxiv - Cancer Biology 2021

  Quote: ... The following antibodies were used: ARL4C (#10202-1-AP, Proteintech), ING1 (#14625 ...
• CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression

  Désirée Schatton, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit polyclonal anti-astrin (#14726-1-AP) antibody from ProteinTech; rabbit polyclonal anti-FLAG (#F7425 ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Antibodies used: Rabbit anti-N-cadherin (#22018-1-AP, Proteintech), 1:1000 ...
• Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by involving an Integrin-αVβ6/TGF-β Signaling Cascade

  Camilla Schinner, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-GAPDH (10494-1-AP, Proteintech, Rosemont, IL, USA), mouse anti-α-tubulin (ab7291 ...
• Chicoric acid prevents neurodegeneration via microbiota-gut-brain axis in a mouse Parkinson’s disease model

  Ning Wang, et al., bioRxiv - Neuroscience 2021

  Quote: ... Secondary antibodies: Goat anti-rabbit IgG (1:8000, B900210, Proteintech) and goat anti-mouse IgG (1:4000 ...
• Diterpenoid Vinigrol activates ATF4/DDIT3-mediated PERK/eIF2α arm of unfolded protein response to drive breast cancer cell death

  Wencheng Wei, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Anti-DDIT3 (15204-1-AP) was from Proteintech (Wuhan, China). Anti-β-tubulin (HC101-02 ...
• NAP1L1 and NAP1L4 binding to Hypervariable Domain of Chikungunya Virus nsP3 Protein is bivalent and requires phosphorylation

  Francisco Dominguez, et al., bioRxiv - Microbiology 2021

  Quote: ... Antibodies used: anti-NAP1L1 rabbit polyclonal antibodies (14898-1, Proteintech), anti-NAP1L4 rabbit polyclonal antibodies (16018-1 ...
• NAP1L1 and NAP1L4 binding to Hypervariable Domain of Chikungunya Virus nsP3 Protein is bivalent and requires phosphorylation

  Francisco Dominguez, et al., bioRxiv - Microbiology 2021

  Quote: ... Antibodies used: anti-NAP1L1 rabbit polyclonal antibodies (14898-1, Proteintech), anti-NAP1L4 rabbit polyclonal antibodies (16018-1 ...
• Phosphatidylinositol 3-kinase-independent synthesis of PtdIns(3,4)P₂ by a phosphotransferase

  Glenn F. W. Walpole, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit pAb anti-PI3K-C2α (ProteinTech 22028-1-AP; RRID:AB_11183760); Mouse mAB anti-c-Myc (DSHB 9E10 ...
• DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation

  Zhiqiang Hou, et al., bioRxiv - Biophysics 2020

  Quote: ... 4 mg of anti-DnaJC7 antibody (Proteintech, 11090-1-AP) were conjugated to 50 μL total Dynabeads™ suspension overnight at 4°C with rotation ...
• GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis

  Qiujie Wang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-FTL (10727-1-AP) was from Proteintech (Shanghai, China), and anti-GSTZ1 (GTX106109 ...
• Develop an efficient and specific AAV based labeling system for Muller glia in mice

  Yanxia Gao, et al., bioRxiv - Neuroscience 2022

  Quote: ... and mouse-anti-Calretinin (1:200, Proteintech, 66496-L-IG), rabbit anti-Pax6 (1:200 ...
• The evolutionary conserved complex CEP90, FOPNL and OFD1 specifies the future location of centriolar distal appendages, and promotes their assembly

  Pierrick Le Borgne, et al., bioRxiv - Cell Biology 2022

  Quote: ... Cep164 (1/1000-Proteintech 22227-1AP, (Bowler et al, 2019)) ...
• Human cytomegalovirus vMIA inhibits MAVS oligomerization at peroxisomes in an MFF-dependent manner

  Ana Rita Ferreira, et al., bioRxiv - Cell Biology 2022

  Quote: Rabbit antibodies against MFF (17090-1-AP, ProteinTech, Manchester, UK) 30 ...
• Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma

  Tilman L. B. Hölting, et al., bioRxiv - Cancer Biology 2022

  Quote: ... monoclonal murine Anti-GAPDH antibody (HRP-60004, 1:50,000, Proteintech).
• Peritoneal M2 macrophage-derived extracellular vesicles as natural multi-target nanotherapeutics to attenuate cytokine storm after severe infections

  Yizhuo Wang, et al., bioRxiv - Immunology 2022

  Quote: ... rabbit anti-TSG101 (14497-1-AP, Proteintech, Rosemont, IL, USA), rabbit anti-Alix (12422-1-AP ...
• Re-direction of phagosomes to the recycling expulsion pathway by a fungal pathogen

  Lei-Jie Jia, et al., bioRxiv - Cell Biology 2022

  Quote: ... and mouse monoclonal anti-GAPDH antibody (Proteintech, 1:2,000 dilution) were used ...