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3951 - 4000 of 5325 citations for 6 Chloro 2 4 chlorophenyl N N dimethylimidazo 1 2 α pyridine 3 methanamine since 2019

• MeCP2 Interacts with the Super Elongation Complex to Regulate Transcription

  Jun Young Sonn, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 5μg AFF4 antibody (Proteintech; 14662-1-AP), and 5μg of normal mouse or rabbit IgG (Millipore ...
• Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution

  Haoran Ma, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and GAPDH (60004-1-Ig, Proteintech Group).
• Deficiency of m⁶A RNA methylation promotes ZBP1-mediated cell death

  Shuang Li, et al., bioRxiv - Molecular Biology 2024

  Quote: ... or anti-YTHDC1 antibody (Proteintech, 1:1000) overnight at 4°C ...
• Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition

  Jiayi Wang, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit polyclonal anti-KI67 (Proteintech, 1:400). Cells were then washed ...
• Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells

  Mariia Mikhova, et al., bioRxiv - Cell Biology 2024

  Quote: ... and anti-Tubulin (Proteintech, 66031-1-Ig). HRP-conjugated secondary antibodies were used at 1:5000 dilutions and chemiluminescence signal was produced using the Clarity western ECL substrate (BioRad ...
• Increase in ER-mitochondria contacts and mitochondrial fusion are hallmarks of mitochondrial activation during embryogenesis

  Anastasia Chugunova, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-SigmaR1 (Proteintech, 15168-1-AP) and rabbit anti-Flag (Cell Signaling ...
• PARP14 mediated SQSTM1/p62 cysteine ADP-ribosylation is counteracted by the SARS-CoV-2 macrodomain

  David Kubon, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-TRIM21 (12108-1-AP, Proteintech), rabbit anti-HA (ab9110 ...
• Cell type specific roles of FOXP1 during early neocortical murine development

  Ana Ortiz, et al., bioRxiv - Neuroscience 2024

  Quote: ... rb-anti-CUX1 (Proteintech 117331, 1:600); rb-anti-Phospho-Histone H3 (Ser10 ...
• Simply crushed Zizyphi spinosi semen prevents neurodegenerative diseases and reverses age-related cognitive decline in mice

  Tomohiro Umeda, et al., bioRxiv - Neuroscience 2024

  Quote: ... 10355-1-AP (Proteintech, Rosemont, IL, USA) for p21CIP1/WAF1 ...
• Photoactivated SOPP3 enables APEX2-mediated proximity labeling with high spatio-temporal resolution in live cells

  Dajun Qu, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-Tim23 (Proteintech, 11123-1-AP), mouse anti-HSP60 (Proteintech ...
• AAV-DJ is Superior to AAV9 for Targeting Brain and Spinal Cord, and De-Targeting Liver Across Multiple Delivery Routes in Mice

  Monika Chauhan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-OLIG2 (#13999-1-AP, Proteintech); rabbit anti-doublecortin (DCX) ...
• E3 ligase Praja1 mediates ubiquitination and degradation of microtubule-associated protein Tau

  Shiho Aoki, et al., bioRxiv - Biochemistry 2024

  Quote: ... and anti-Tau (#10274-1-AP, Proteintech) were used ...
• Sustaining microglial reparative function enhances stroke recovery

  Jun Tsuyama, et al., bioRxiv - Pathology 2024

  Quote: ... or anti-GDF15 (Proteintech, 27455-1-AP) overnight at 4°C ...
• A long-lived pool of PINK1 imparts a molecular memory of depolarisation-induced activity

  Liam Pollock, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Actin (mouse, 66009, 1:10000, Proteintech), anti-TOMM20 (rabbit ...
• TCTEX1D2 has two distinct functions in sperm flagellum formation in mice; cytoplasmic dynein 2 and inner dynein arm

  Ryua Harima, Kenshiro Hara, Kentaro Tanemura, bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-KIF3A (13930-1-AP, Proteintech), and rabbit anti-IFT140 antibody (17460-1-AP ...
• Targeting IDH1-Mutated Oligodendroglioma with Acid Ceramidase Inhibitors

  Helena Muley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-TRIB3 (13300-1-AP Proteintech), mouse anti-beta actin (ab6276 abcam) ...
• A host enzyme reduces non-alcoholic fatty liver disease by inactivating intestinal lipopolysaccharide

  Zhiyan Wang, et al., bioRxiv - Immunology 2024

  Quote: ... anti-Lamin B1 (12987-1-AP, Proteintech), anti-Phospho-mTOR (Ser2448 ...
• TMEM165 replenishes lysosomal Ca²⁺ stores, protects cells against Ca²⁺ overload, and mediates Ca²⁺-induced lysosomal H⁺ leakage

  Ran Chen, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-TMEM165 (20485-1-AP) from Proteintech Europe ...
• Centromere protection requires strict mitotic inactivation of the Bloom syndrome helicase complex

  María Fernández-Casañas, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-TOP3A (Proteintech; 14525, 1:500). HRP-conjugated secondary antibodies ...
• H2A.Z deposition at meiotic prophase I underlies homologous recombination and pachytene genome activation during male meiosis

  Shenfei Sun, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-RPA2 (Proteintech, 10412-1-AP), rabbit anti-MLH1 (Cell Signaling Technology ...
• CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer

  Chunge Zhong, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cyclin B1 (Proteintech, Cat# 55004-1-AP), CDK1 (Proteintech ...
• m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation

  Pierre Klein, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-MAP1B (Proteintech, 21633-1-AP), mouse anti-MAP2 (Abcam ...
• GRAS1 non-coding RNA protects against DNA damage and cell death by binding and stabilizing NKAP

  Tong Su, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Lamin A/C (10298-1-AP, Proteintech), PARP1 (13371-1-AP ...
• CEP44 is required for maintaining centriole duplication and spindle integrity

  Donghui Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-KEAP1 polyclonal antibody (1:200; Proteintech), and anti-Nrf2 polyclonal antibody (1:200 ...
• Photoactivated SOPP3 enables APEX2-mediated proximity labeling with high spatio-temporal resolution in live cells

  Dajun Qu, et al., bioRxiv - Molecular Biology 2024

  Quote: ... mouse anti-HSP60 (Proteintech, 66041-1-Ig), mouse anti-α-Tubulin (Sigma-Aldrich ...
• Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells

  Mariia Mikhova, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Lamin B1 (Proteintech, 12987-1-AP), and anti-Tubulin (Proteintech ...
• The myosin regulatory light chain Myl5 localizes to mitotic spindle poles and is required for proper cell division

  Ivan Ramirez, et al., bioRxiv - Cell Biology 2020

  Quote: ... and immunoprecipitations were carried out using antibodies against: Myl5 and MYO10 (Proteintech: 14249-1-AP and 24565-1-AP); Pericentrin (Novus Biologicals ...
• Confined Migration Induces Heterochromatin Formation and Alters Chromatin Accessibility

  Chieh-Ren Hsia, et al., bioRxiv - Cell Biology 2021

  Quote: ... membranes were incubated with loading control primary antibody (mouse anti-histone H3, Abcam, ab195277, 1:5,000; rabbit anti-histone H3, Cell Signaling, 4499, 1:1,000; mouse anti-GAPDH, Proteintech, 60004-1-Ig ...
• Extracellular Matrix Stiffness Alters TRPV4 Regulation in Chondrocytes

  Nicholas Trompeter, et al., bioRxiv - Cell Biology 2021

  Quote: ... TRPV4 and GAPDH were probed with rabbit anti-TRPV4 (1:500, Alomone Labs) and rabbit anti-GAPDH (1:5,000, Proteintech) overnight.
• The evolutionary conserved complex CEP90, FOPNL and OFD1 specifies the future location of centriolar distal appendages, and promotes their assembly

  Pierrick Le Borgne, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-MNR/KIAA0753 (1/250 - Novusbio NBP1-90929) anti-Cep89 (1/800-Proteintech 24002-1AP, (Kanie et al, 2017)) ...
• Effect of GDF15 on acetaminophen (APAP)-induced liver injury in mice

  Peng Jiang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... Antibodies against JNK (cat. no. 66210-1-Ig) and tubulin (cat. no. 11224-1-AP) were bought from ProteinTech.
• Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia

  Alaullah Sheikh, et al., bioRxiv - Microbiology 2022

  Quote: ... then blotted onto polyvinylidene difluoride (PVDF) membranes and probed with anti-SLC19A3 (1:1000; Cat# 13407-1-AP; Proteintech), or anti-SP1 (1:1000 ...
• SCARECROW maintains the stem cell niche in Arabidopsis root by ensuring telomere integrity

  Bingxin Wang, et al., bioRxiv - Plant Biology 2021

  Quote: ... as the primary antibody and an HRP-conjugated Affinipure Goat Anti-Mouse antibody (Proteintech, SA00001-1; 1:2500 dilution) as the secondary antibody ...
• Bi-phasic effect of gelatin in myogenesis and skeletal muscle regeneration

  Xiaoling Liu, et al., bioRxiv - Physiology 2021

  Quote: Primary antibodies against MyoD (18943-1-AP) and myogenin (67082-1-Ig) were purchased from Proteintech (Wuhan, Hubei, China). Primary antibodies against β-actin (BF0198) ...
• Glycerolipid defects in skeletal muscle contribute to rhabdomyolysis in Tango2 deficiency

  Jennifer G Casey, et al., bioRxiv - Genetics 2022

  Quote: Membranes were blocked in PBS containing 5% casein/0.1% Tween 20 and incubated with either rabbit polyclonal anti Tango2 (1:250, 27846-1-AP, Proteintech) or mouse monoclonal anti-α-tubulin (1:500 ...
• HepaCAM Suppresses Glioblastoma Stem Cell Invasion in the Brain

  Arpan De, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Immunohistochemical analyses were performed with the following primary antibodies: rabbit anti-hepaCAM (Proteintech 18177-1-ap, 1:200 dilution), anti-Mlc1 antibody (Novus Biologicals ...
• D-mannose suppresses macrophage release of extracellular vesicles and ameliorates type 2 diabetes

  Sha Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Vinculin (Abmart, China; diluted at 1:1000) and anti-β-actin antibodies (Proteintech, China; diluted at 1:2500). After washing with TBS containing 0.1% Tween-20 ...
• The FIGNL1-FIRRM complex is required to complete meiotic recombination in the mouse and prevents massive DNA damage-independent RAD51 and DMC1 loading

  Akbar Zainu, et al., bioRxiv - Genetics 2023

  Quote: ... Cytoplasmic and nuclear fractions were analyzed by western blotting with rabbit anti-FIGNL1 (1/500, Proteintech, 17604-1-AP), rabbit anti-FIRRM (1/500 ...
• Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins

  John Fehilly, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The following primary antibodies and dilutions were used in our study: anti-SMAUG1 (Proteintech, 17387-1-AP, 1:1000), anti-AKT (Cell Signaling Technology ...
• Transcript errors generate a continuous stream of amyloid and prion-like proteins in human cells

  Claire S. Chung, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Membranes were incubated overnight for 16 hours with 1:500 MGMT primary antibody (67476-1-Ig; Proteintech, Rosemead, IL). Membranes incubated with IRDye 800CW and/or 700CW secondary antibodies and visualized with a LI-COR Odyssey C1920 ...
• CEP76 is a critical regulator of male germ cell transition zone function and tail composition

  Brendan J. Houston, et al., bioRxiv - Cell Biology 2023

  Quote: ... For other antibodies (2.8 µg/ml AKAP4 [ProteinTech 24986-1-AP], 0.8 µg/ml SUN5 [ProteinTech 17495-1-AP]) sperm were permeabilised in 0.5% Triton-X-100/PBS ...
• Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD

  Elias Adriaenssens, et al., bioRxiv - Cell Biology 2023

  Quote: The primary antibodies used in this study are: anti-4E-BP1 (1:1000, Proteintech Cat# 60246-1-Ig, RRID:AB_2881368), anti-ATG5 (1:1000 ...
• PAN deadenylase ensures proper mitosis under conditions of microtubule stress by regulating spindle integrity and promoting cell survival

  Jigyasa Verma, et al., bioRxiv - Cell Biology 2024

  Quote: ... Pan2 knockdown efficiency was then determined by Western blotting (1:1000 of Proteintech 16427-1-AP against human Pan2).
• Granzyme K drives a newly-intentified pathway of complement activation

  Carlos A. Donado, et al., bioRxiv - Immunology 2024

  Quote: ... and cleavage of C4 was assessed by immunoblot using an anti-C4 antibody (22233-1-AP, Proteintech, 1:1,000). The C4b fragment was identified by comparison to the band corresponding to serum-purified C4b (Complement Technology ...
• The tricellular junction protein ILDR2 in glomerulopathies: insights and implications

  Florian Siegerist, et al., bioRxiv - Cell Biology 2024

  Quote: ... Blots were incubated for 1 h at RT with HRP–conjugated secondary antibody anti-mouse (SA00001-1, Proteintech Group) or anti-rabbit (SA00001-2 ...
• Endosomal spatio-temporal modulation of the cortical RhoA zone conditions epithelial cell organization

  Gaston Cécile, et al., bioRxiv - Cell Biology 2020

  Quote: ... Monoclonal antibody directed against GAPDH (#60004-1-Ig, clone 1E6D9, WB dilution, 1:500) was from Proteintech (Chicago, IL, USA). Rabbit polyclonal antibody directed against Myosin-IIA (#909801 ...
• The zinc finger antiviral protein ZAP destabilises viral transcripts and restricts human cytomegalovirus

  Ana Cristina Gonzalez-Perez, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Mouse monoclonal anti-hZAP (ZC3HAV1) (#66413-1-Ig, clone 1G10B9) and rabbit polyclonal anti-hZAP (#16820-1-AP) were obtained from Proteintech. Mouse monoclonal anti-actin (A5441 ...
• A programmable system to methylate and demethylate m⁶A on specific mRNAs

  Chen Chang, et al., bioRxiv - Cell Biology 2021

  Quote: ... Immuno-detection was performed using HRP-conjugated Affinipure Goat Anti-Mouse IgG(H+L) (1:5000, SA0 001-1, Proteintech) or HRP-conjugated Affinipure Goat Anti-Rabbit IgG(H+L ...
• The Endoplasmic Reticulum Membrane Complex Promotes Proteostasis of GABA_A Receptors

  Angela Whittsette, Ya-Juan Wang, Ting-Wei Mu, bioRxiv - Cell Biology 2022

  Quote: ... The rabbit polyclonal EMC2 antibody (catalog #: 25443-1-AP) and mouse monoclonal EMC8 antibody (catalog #:66547-1-IG) were obtained from Proteintech. The rabbit polyclonal EMC5 antibody (catalog # ...
• Structure and functional mapping of the KRAB-KAP1 repressor complex

  Guido A. Stoll, et al., bioRxiv - Biochemistry 2022

  Quote: ... samples were incubated for 1 h with the primary antibody (mouse anti-KAP1, Proteintech, cat. no. 66630-1-Ig, RRID:AB_2732886) diluted 1:500 in PBS and 10% FBS ...