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301 - 350 of 700 citations for N Furan 2 ylmethyl 3 bromo 4 fluoro benzamide since 2020

• Loss of the lysosomal protein CLN3 modifies the lipid content of the nuclear envelope leading to DNA damage and activation of YAP1 pro-apoptotic signaling

  Neuza Domingues, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-PLA2G15 (Proteintech, 10863-2-AP; IB 1:1000).
• The mitochondrial stress-induced protein carboxyl-terminal alanine and threonine tailing (msiCAT-tailing) promotes glioblastoma tumorigenesis by modulating mitochondrial functions

  Ting Cai, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-ANT1/2 (1:1000, Proteintech, cat. xxx), rabbit anti-CypD (1:1000 ...
• RUNX2 Isoform II Protects Cancer Cells from Ferroptosis by Promoting PRDX2 Expression in Oral Squamous Cell Carcinoma

  Junjun Huang, Rong Jia, Jihua Guo, bioRxiv - Cancer Biology 2024

  Quote: ... rabbit PRDX2 antibody (1:2000, Proteintech, #10545-2-AP) and mouse actin antibody (1:5000 ...
• Structural details of helix-mediated TDP-43 C-terminal domain multimerization

  Azamat Rizuan, et al., bioRxiv - Biochemistry 2024

  Quote: ... probing with TDP-43 antibody (10782-2-AP, Proteintech).
• Ccdc66 regulates primary cilium stability, disassembly and signaling important for epithelial organization

  Jovana Deretic, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-β-Catenin (ProteinTech PTG 51067-2-AP) at 1:200 ...
• Deep Visual Proteomics Unveils Precision Medicine Insights in Composite Small Lymphocytic and Classical Hodgkin Lymphoma

  Xiang Zheng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... / anti-IRF4 antibody (1:100, 11247-2-AP, Proteintech) / anti-LENG1 antibody (1:500 ...
• Fibroblasts carrying intermediate C9orf72 hexanucleotide repeat expansions from iNPH patients show impaired energy metabolism but no cell pathologies

  Dorit Hoffmann, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-TDP-43 (1:1000, 10782-2-AP, Proteintech), anti-phospho-TDP-43 (1:1000 ...
• C9orf72 repeat expansion-carrying iPSC-microglia from FTD patients show increased phagocytic activity concomitantly with decreased number of autophagosomal-lysosomal vesicles

  Hannah Rostalski, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-TDP-43 (1:500, 10782-2-AP; Proteintech), anti-TMEM119 (1:250 ...
• C9orf72 repeat expansion-carrying iPSC-microglia from FTD patients show increased phagocytic activity concomitantly with decreased number of autophagosomal-lysosomal vesicles

  Hannah Rostalski, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-TDP-43 (1:2,000, 10782-2-AP; Proteintech). Next ...
• ASO-enhancement of TARDBP exitron splicing mitigates TDP-43 proteinopathies

  Takuma Yamagishi, et al., bioRxiv - Neuroscience 2024

  Quote: ... primary antibodies against TDP-43 (Proteintech, 10782-2-AP), GFP (Proteintech ...
• Induction of NASH in the Nwd1^−/− mouse liver via SERCA2-dependent endoplasmic reticulum stress

  Seiya Yamada, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-ADP/ATP translocase 1/2 (ANT1/2, rabbit polyclonal, #17796-1-AP, RRID: AB_2190358, Proteintech, Rosemont, IL, USA; 1:2000 for WB), anti-voltage-dependent anion-selective channel protein 1 (VDAC1)/porin (mouse monoclonal ...
• 5’ UTR variants in the quantitative trait gene Hnrnph1 support reduced 5’ UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity

  Qiu T. Ruan, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 3) hnRNP H1 antibody (1:10,000, Proteintech, Rosemont, IL, USA; Cat# 14774-1-AP). The secondary used for the Bethyl and Proteintech antibodies was donkey anti-rabbit HRP (1:10,000 ...
• Flavinated SDHA Underlies the Change in Intrinsic Optical Properties of Oral Cancers

  Tomoko Marumo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... along with anti-GAPDH (Glyceraldehyde 3-phosphate dehydrogenase) antibody (Proteintech Group Inc, Rosemont, IL, USA) as an internal control ...
• Lysosome-acidifying nanoparticles rescue A30P α-synuclein induced neuronal death in cellular and Drosophila models of Parkinson’s disease

  Chih Hung Lo, et al., bioRxiv - Neuroscience 2024

  Quote: ... the cells were stained with primary antibodies against galectin-3 (Proteintech, Cat# 14979-1-AP) overnight at 4 °C ...
• TMEM184b is necessary for IL-31 induced itch

  Erik G. Larsen, et al., bioRxiv - Neuroscience 2021

  Quote: ... sections were incubated overnight at 4°C with rabbit NeuN (1:250, Proteintech), or for 1 hour with Alexa Fluor® 488 Mouse anti-β-Tubulin ...
• De-novo purine biosynthesis is a major driver of chemoresistance in glioblastoma

  Jack M Shireman, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Samples were incubated overnight at 4°C for antibody crosslinking (anti-HA, ProteinTech; Normal Rabbit IgG ...
• The TRIP6/LATS1 complex constitutes the tension sensor of α-catenin/vinculin at both bicellular and tricellular junctions

  Lin Xie, et al., bioRxiv - Cell Biology 2023

  Quote: ... CoraLite 594-conjugated Goat AntiRabbit IgG(H+L) (Proteintech, SA00013-4, 1:500), Alexa Fluor 594 Streptavidin Alexa Fluor (yeasen ...
• Mast-Cell Expressed Membrane Protein-1 (MCEMP1) is expressed in classical monocytes and alveolar macrophages in Idiopathic Pulmonary Fibrosis and regulates cell chemotaxis, adhesion, and migration in a TGFβ dependent manner

  Carole Y. Perrot, et al., bioRxiv - Immunology 2023

  Quote: ... and incubated overnight at 4°C with mouse anti-SMAD3 (Proteintech, 1:400) and rabbit anti-SP1 (Abcam ...
• PATJ regulates cell stress responses and vascular remodeling post-stroke

  Mengqi Zhang, et al., bioRxiv - Neuroscience 2024

  Quote: ... Overnight incubation at 4°C with primary antibodies targeting YAP1 (1:200, Proteintech) was followed by application of goat anti-rabbit Alexa Fluor 488 secondary antibody (1:1000 ...
• Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

  Avital Licht-Murava, et al., bioRxiv - Neuroscience 2022

  Quote: ... Primary antibodies were raised against TDP-43 (1:2000 pan-specific rabbit anti-TDP-43 ProteinTech #10782-2-AP; RRID # AB_615042 or 1:2000 human-specific mouse anti-TDP-43 ProteinTech #60019-2-Ig; RRID #AB_2200520), β-actin (1:2000 ...
• Tryptophan residues in TDP-43 and SOD1 mediate the cross-seeding and toxicity of SOD1

  Edward Pokrishevsky, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-TDP-43 antibody (#60019-2-Ig, Proteintech, USA), mouse anti-misfolded SOD1 monoclonal antibody 3H1 generated by Cashman lab (11) ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-TDP-43 (Proteintech 10782-2-AP, 1:2000), rabbit anti-Ubc9 (Abcam ...
• TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV

  Roy Matkovic, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-MTR4 (For WB and IP: 12719-2-AP, Proteintech) 1/1000 ...
• MOSPD2 a new endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis

  Mehdi Zouiouich, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Calnexin (1:1000; 10427-2-AP, Proteintech, RRID:AB_2069033), anti-Perilipin3 (1:1000 ...
• TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

  Manling Xie, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-TDP-43 (1:1000, Proteintech, 10782-2-AP), rabbit anti-GFP (1:1000 ...
• δ-protocadherins control neural progenitor cell proliferation by antagonizing Ryk and Wnt/β-catenin signaling

  Sayantanee Biswas, et al., bioRxiv - Neuroscience 2020

  Quote: ... and incubated with either 2 μg rabbit anti-Ryk (Proteintech) or rabbit anti-Pcdh19 (custom made by Covance ...
• RNA is required for the maintenance of multiple cytoplasmic and nuclear membrane-less organelles

  Carolyn J. Decker, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-ZFP36L1/2 (TIS11B) antibody (Proteintech 12306-1-AP) 1:500 ...
• Lineage transcription factors co-regulate subtype-specific genes providing a roadmap for systematic identification of small cell lung cancer vulnerabilities

  Karine Pozo, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and rabbit anti-PROX1 (10 μg; Proteintech 11067-2-AP).
• Pore-forming protein βγ-CAT promptly responses to fasting with capacity to deliver macromolecular nutrients

  Zhi-Hong Shi, et al., bioRxiv - Cell Biology 2022

  Quote: ... Coralite488-conjugated goat anti-rabbit IgG (Proteintech, Cat SA00013-2) and coralite594-conjugated goat anti-mouse IgG (Proteintech ...
• Pore-forming protein βγ-CAT promptly responses to fasting with capacity to deliver macromolecular nutrients

  Zhi-Hong Shi, et al., bioRxiv - Cell Biology 2022

  Quote: ... and HRP-goat anti-rabbit IgG (Proteintech, Cat SA00001-2) secondary antibodies were used in these experiments.
• Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization

  Sean R. Kundinger, et al., bioRxiv - Biochemistry 2021

  Quote: ... rabbit polyclonal anti-TDP-43 (ProteinTech Group 10782-2-AP), rabbit anti-pS409-410 TDP-43 (CosmoBio ...
• RNA-binding protein Orb2 causes microcephaly and supports centrosome asymmetry in Drosophila neural stem cells

  Beverly V. Robinson, et al., bioRxiv - Cell Biology 2022

  Quote: ... and rabbit anti-GFP (1:700; Proteintech, 50430-2-AP). Secondary antibodies ...
• Alternative splicing of the stress-sensitive regulator CIRBP sharpens the cellular response to bacterial infection

  Morgane Corre, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Anti-CIRBP (Proteintech, cat#10209-2- AP, 1:500 dilution); anti-β-Tubulin (Biolegend ...
• Regulating PCCA gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia

  Ulrika Simone Spangsberg Petersen, et al., bioRxiv - Molecular Biology 2023

  Quote: ... TDP-43 (1:1000; 10782-2-AP; Proteintech; Rosemont, IL), and hnRNP K (1:1000 ...
• CCR9 overexpression promotes T-ALL progression by enhancing cholesterol biosynthesis

  Muhammad Jamal, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HRP-conjugated anti-rabbit IgG secondary antibodies (Proteintech, SA00001-2).
• Epstein–Barr Virus BALF0/1 Subverts the Caveolin and ERAD Pathways to Target B-cell Receptor Complexes for Degradation

  Stephanie Pei Tung Yiu, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-GFP tag rabbit polyclonal antibody (Proteintech #50430-2-AP), goat anti-rabbit IgG ...
• Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer

  Rou Zhang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... MMP2 antibody (1:1000; Catalog No. 10373-2-AP, Proteintech), Cingulin antibody (1:1000 ...
• Lysosomal swelling and lysis mediate delivery of C3 toxins to their cytoplasmic targets

  Madison Turner, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-ALG-2 (catalogue #12303-1-AP) was from Proteintech; anti-rabbit secondary antibodies conjugated with Alexa Fluor 488 and Alexa Fluor 647 were from Jackson ImmunoResearch Labs ...
• Comparing the value of mono- versus coculture for high-throughput compound screening in hematological malignancies

  Sophie A. Herbst, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-rabbit-IgG-HRP-conjugated (Proteintech Group, #SA00001-2). A detailed description of the protocol can be found in the supplementary methods of this manuscript.
• UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation independently of the p97 ATPase

  Brittany A. Ahlstedt, et al., bioRxiv - Cell Biology 2022

  Quote: ... and G3BP1 (13057-2-AP) antibodies were obtained from Proteintech Inc ...
• Wnt5a-Ror2 signaling activates p62-Nrf2 axis in reactive astrocytes after brain injury

  Mitsuharu Endo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and rabbit anti-Keap1 (Proteintech, 10503-2-AP, 1:200). Alexa Fluor 488 Tyramide SuperBoost Kit ...
• RUNX2 Isoform II Protects Cancer Cells from Ferroptosis by Promoting PRDX2 Expression in Oral Squamous Cell Carcinoma

  Junjun Huang, Rong Jia, Jihua Guo, bioRxiv - Cancer Biology 2024

  Quote: ... The concentration of PRDX2 (Proteintech, Wuhan, China, #10545-2-AP), 4-HNE (Abcam ...
• GRAS1 non-coding RNA protects against DNA damage and cell death by binding and stabilizing NKAP

  Tong Su, et al., bioRxiv - Molecular Biology 2024

  Quote: ... TDP-43 as a positive control (10782-2-AP, Proteintech), and NKAP ...
• CLCC1 Governs Bilayer Equilibration at the Endoplasmic Reticulum to Maintain Cellular and Systemic Lipid Homeostasis

  Lingzhi Wu, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit polyclonal anti-FASN (Proteintech, 10624-2-AP, 1:1,000); rabbit polyclonal anti-ACC1 (Proteintech ...
• Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia

  Zhengming Tian, et al., bioRxiv - Cell Biology 2024

  Quote: ... and the EV-negative marker calnexin (Proteintech, 10427-2-AP).
• Fluorescence lifetime-based FRET biosensors for monitoring N-terminal domain interactions of TDP-43 in living cells: A novel resource for ALS and FTD drug discovery

  Noah Nathan Kochen, et al., bioRxiv - Neuroscience 2024

  Quote: ... blots were probed with TDP-43 (Proteintech 10782-2-AP), mNeonGreen (Cell Signaling Technology E6M3D) ...
• CLCC1 Governs Bilayer Equilibration at the Endoplasmic Reticulum to Maintain Cellular and Systemic Lipid Homeostasis

  Lingzhi Wu, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit polyclonal anti-Calnexin (Proteintech, 10427-2-AP, 1:1,000); rabbit polyclonal anti-ApoB (Proteintech ...
• Research Brief: Translation Initiation Represents an Acute Myeloid Leukemia Cell Vulnerability That Can Be Co-Targeted With BCL-2 Inhibition

  Yoke Seng Lee, et al., bioRxiv - Cancer Biology 2024

  Quote: ... BCL-2 (12789-1-AP) antibody was purchased from Proteintech. Quantification of protein expression was expressed relative to DMSO control ...
• CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function

  Longxin Xie, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit-anti-TDP-43 (Proteintech, 10782-2-AP, 1:2500), and rabbit-anti-mCherry (Cell Signaling ...
• Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans

  Xue Wen Ng, et al., bioRxiv - Cell Biology 2024

  Quote: ... along with Cplx 2 (18149-1-AP; 1:50; Proteintech) overnight at 4°C ...