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251 - 300 of 5772 citations for 3 Hydrazino 5 methyl 4H 1 2 4 triazol 4 ylamine hydrochloride since 2020

• Annexin A1 is a polarity cue that directs planar mitotic spindle orientation during mammalian epithelial morphogenesis

  Maria Fankhaenel, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-ANXA1 (10 μg/ml, Proteintech #66344-1-Ig; 3 μg/ml, Proteintech #21990-1-AP), anti-S100A11 (10 μg/ml ...
• Nrf2 represses ER stress-related ferroptosis in renal carcinoma cells via HO-1

  Yuanqing Shen, et al., bioRxiv - Cancer Biology 2020

  Quote: ... microtubule-associated protein 1 light chain 3 beta (LC3B) (Proteintech Group, USA), caspase 3 (Proteintech Group ...
• Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

  Ferrol I. Rome, et al., bioRxiv - Physiology 2022

  Quote: ... succinyl-CoA:3-oxoacid-CoA transferase (SCOT, Proteintech, 12175-1-AP; RRID:AB_2157444), Total OXPHOS Rodent WB Antibody Cocktail (Abcam ...
• A direct estrogenic involvement in the expression of human hypocretin

  Haimei Li, et al., bioRxiv - Neuroscience 2023

  Quote: ... and anti-mouse Alexa 594 (1:400 dilution, SA00013-3, Proteintech, China) were added to the slides for 1 hour and subsequently washed in PBS (3X5 min each) ...
• G₂C₄ targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in C9orf72 ALS/FTD human neurons

  Jeffrey D. Rothstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... Blots were blocked for 30 minutes with 5% nonfat milk in 1X TBST (0.1% Tween-20) and incubated overnight at 4°C with Mouse Anti-TDP-43 (ProteinTech) primary antibody diluted in block ...
• The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation

  Magda Wąchalska, et al., bioRxiv - Cell Biology 2023

  Quote: ... pre-cleared cell lysates were rotated overnight at 4°C with anti-UL49.5 antibodies (H11) or anti-TAP1 antibodies (Proteintech) together with Protein-A Sepharose beads (Merck) ...
• TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteins

  Jesús Muñoz-Estrada, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cell lysates were centrifuged 17,000x g for 10 min at 4°C and supernatants were incubated with ChomoTek GFP-Trap Agarose beads (Proteintech) for 1 h at 4°C followed by bead sedimentation and washing according to manufacturer’s instructions ...
• Genome-wide mapping of autonomously replicating sequences in the marine diatom Phaeodactylum tricornutum

  Hyun-Sik Yun, et al., bioRxiv - Molecular Biology 2024

  Quote: ... The diluted samples (500 µl) were mixed with antibody (anti-DYKDDDDK tag, 66008-4-Ig; Proteintech, Rosemont, IL, USA)-coated beads (Dynabeads protein G ...
• DHX36 binding induces RNA structurome remodeling and regulates RNA abundance via m⁶A/YTHDF1

  Yuwei Zhang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 5 μg of antibodies against YTHDF1 (Proteintech 17479-1-AP) or isotype IgG (Santa Cruz Biotechnology ...
• A tale of two tumors: differential, but detrimental, effects of glioblastoma extracellular vesicles (EVs) on normal human brain cells

  Mary Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... used at 1:500 dilutions in 5% NFDM/TBST (Proteintech Group ...
• The versatility of Ascorbate Peroxidase-aided mapping uncovers insights of the nuclear lamina interactions and function

  Joseph R. Tran, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-SRSF1 (1:2500, ProteinTech, #12929-2-AP).
• Sequestration of TDP-43^216-414 aggregates by cytoplasmic expression of the proSAAS chaperone

  Juan R. Peinado, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-TDP-43 (Proteintech 10782-2-AP, 1:1000), or anti-PGK1 (Invitrogen 459250 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-G3BP1 (Proteintech 13057-2-AP, 1:500), goat anti-Importin β-1 (Santa Cruz sc-1863 ...
• Substrate-induced clustering activates Trim-Away of pathogens and proteins

  Jingwei Zeng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit anti-GFP (Proteintech 50430-2-AP; 1:1000), rabbit anti-GFP (Abcam ...
• Substrate-induced clustering activates Trim-Away of pathogens and proteins

  Jingwei Zeng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit anti-GFP (Proteintech 50430-2-AP; 1:1000), mouse anti-CyPB (k3E2 ...
• Multiple Ciliary Localization Signals Control INPP5E Ciliary Targeting

  Dario Cilleros-Rodriguez, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-EGFP (Proteintech, 50430-2-AP, WB: 1:1000), anti-ARL13B (Proteintech ...
• A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia

  Feng Long, et al., bioRxiv - Genomics 2020

  Quote: ... anti-MYC (1:10000, 60003-2-Ig, Proteintech Group), anti-SMAD1 (1:1000 ...
• A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia

  Feng Long, et al., bioRxiv - Genomics 2020

  Quote: ... anti-HA (1:10000, 66006-2-Ig, Proteintech Group), anti-MYC (1:10000 ...
• Lineage transcription factors co-regulate subtype-specific genes providing a roadmap for systematic identification of small cell lung cancer vulnerabilities

  Karine Pozo, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-PROX1 (1:2000; Proteintech 11067-2-AP), rabbit anti-NFIB (1:4000 ...
• The novel chaperone protein SRCP1 reduces insoluble SOD1 protein in vivo without extending ALS mouse lifespan

  Ian W. Luecke, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-TDP43 (Proteintech 10782-2-AP, 1:1000), rat anti-HSP70 (Cell Signaling 4873S ...
• TDP-43 stabilizes transcripts encoding stress granule protein G3BP1: potential relevance to ALS/FTD

  Hadjara Sidibé, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-G3BP1 (1:4500, Proteintech, 13057-2-AP), and guinea pig anti-FluoroGold (1:750 ...
• Neuronal activity regulates Matrin 3 levels and function in a calcium-dependent manner through calpain cleavage and calmodulin binding

  Ahmed M. Malik, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-TDP43 (1:5000, Proteintech 10782-2-AP); rabbit anti-phospho-PKA substrate (1:1000 ...
• Cortical hyperexcitability drives dying forward ALS symptoms and pathology in mice

  Mouna Haidar, et al., bioRxiv - Neuroscience 2021

  Quote: ... and TDP-43 (Rabbit, 1:1000,10782-2-AP, Proteintech). Blots were washed three times in TBST the following day in 10 minute intervals and incubated with 800CW secondary antibody (1:10,000 ...
• Cyclin G2 inhibits oral squamous cell carcinoma growth and metastasis by binding to insulin-like growth factor binding protein 3 and regulating the FAK-SRC-STAT signaling pathway

  Danning Wang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MMP9 (1:500, 10375-2-AP, Proteintech, ID, USA); β-actin (1:1000 ...
• Deficiency of intellectual disability-related gene Brpf1 reduced inhibitory neurotransmission and Map2k7 expression in GABAergic interneurons

  Jingli Cao, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-GFP (Proteintech, 50430-2-AP, 1:500), mouse anti-GABA (Sigma ...
• The versatility of Ascorbate Peroxidase-aided mapping uncovers insights of the nuclear lamina interactions and function

  Joseph R. Tran, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-SRSF1 (1:2500, ProteinTech, #12929-2-AP), rabbit anti-SRSF7 (1:2500 ...
• Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy

  Kristen N. Haggerty, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-centrin-2 (Proteintech Cat# 15877-1-AP, RRID:AB_2077383), anti-STX3 (Millipore Cat# MAB2258 ...
• GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

  Liang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-GFP (1:4000, 50430-2-AP, Proteintech), mouse anti-MT-CO1 (1:2000 ...
• Dysregulated actin dynamics and cofilin correlate with TDP-43 pathology in sporadic amyotrophic lateral sclerosis

  Cyril Jones Jagaraj, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-TDP-43 (Proteintech, #10782-2-AP, 1:1000), anti-β-actin clone C4 (Merck ...
• hnRNP R is a regulator of stress granule formation

  Changhe Ji, bioRxiv - Neuroscience 2022

  Quote: ... primary antibody g3bp1(1:500, Proteintech,13057-2-AP), TIAR (1:500 ...
• Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

  Ferrol I. Rome, et al., bioRxiv - Physiology 2022

  Quote: ... glycogen synthase 2 (GS; Proteintech, 22371-1-AP; RRID:AB_2879091), mitochondrial encoded cytochrome c oxidase II (MT-CO2 ...
• TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves

  Matthew Grove, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-IDI1 (Proteintech, #11166-2-AP; 1:1000). Control whole rabbit IgG for immunoprecipitations was from Jackson Laboratories (011-000-003 ...
• Lysosomal uptake of mtDNA mitigates heteroplasmy

  Parisa Kakanj, et al., bioRxiv - Cell Biology 2024

  Quote: ... α-Calnexin (10427-2-AP; 1:500) from Proteintech; monoclonal α-dsDNA (ab27156 ...
• The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male mice

  Tegan S. Horan, et al., bioRxiv - Genetics 2023

  Quote: ... RUVBL1 (rabbit) pAb 1:1000 (Proteintech 10210-2-AP); and ADAD2 (rabbit ...
• 14-3-3 protein augments the protein stability of phosphorylated spastin and promotes the recovery of spinal cord injury through its agonist intervention

  Qiuling Liu, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-GFP (1:10000, 50430-2-AP from Proteintech), anti-Flag (1:1000 ...
• Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins

  M. Alejandra Zeballos C., et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit anti-ubiquitin (1:200, Proteintech, 10201-2-AP), chicken anti-NeuN (1:500 ...
• Recruitment of FBXO22 for Targeted Degradation of NSD2

  David Y. Nie, et al., bioRxiv - Biochemistry 2023

  Quote: ... SKP1 (1:1000 dilution; Proteintech 10990-2-AP; RRID:AB_2187492), CUL1 (1:1000 dilution ...
• Chaperones Hsc70 and Hsp70 Play Distinct Roles in Bocaparvovirus Minute Virus of Canines Infection

  Jianhui Guo, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-ubiquitin (10201-2-AP; Proteintech; WB: 1:500); anti-NS1 (WB ...
• Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans

  Qian Zhao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-NRBP1/2 antibody (21549-1-AP, Proteintech Europe), Phospho-Histone γH2AX antibody (Ser139 ...
• Hepatocyte Differentiation From Mouse Liver Ductal Organoids By Transducing Four Liver-Specific Transcription Factors

  Katsuhiro Tomofuji, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-PROX1 (Proteintech, 11067-2-AP, 1:1000), rabbit anti-FOXA1 (Abcam ...
• C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress

  ME Cicardi, et al., bioRxiv - Neuroscience 2023

  Quote: ... GFP (WB dilution 1:1,000 Proteintech #50430-2-AP), NeuN (IF dilution 1:2,000 Novus Biologicals #NBP1-92693) ...
• Biallelic Variants in MAD2L1BP (p31^comet) Cause Female Infertility Characterized by Oocyte Maturation Arrest

  Lingli Huang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and Myc (1:5000, Proteintech, Cat #60003-2-Ig). Beta-actin (1:10000 ...
• Wnt5a-Ror2 signaling activates p62-Nrf2 axis in reactive astrocytes after brain injury

  Mitsuharu Endo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-Keap1 (Proteintech, 10503-2-AP, 1:1000), rabbit anti-NBR1 (Cell Signaling Technology ...
• Loss of the lysosomal protein CLN3 modifies the lipid content of the nuclear envelope leading to DNA damage and activation of YAP1 pro-apoptotic signaling

  Neuza Domingues, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-PLA2G15 (Proteintech, 10863-2-AP; IB 1:1000).
• The mitochondrial stress-induced protein carboxyl-terminal alanine and threonine tailing (msiCAT-tailing) promotes glioblastoma tumorigenesis by modulating mitochondrial functions

  Ting Cai, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-ANT1/2 (1:1000, Proteintech, cat. xxx), rabbit anti-CypD (1:1000 ...
• RUNX2 Isoform II Protects Cancer Cells from Ferroptosis by Promoting PRDX2 Expression in Oral Squamous Cell Carcinoma

  Junjun Huang, Rong Jia, Jihua Guo, bioRxiv - Cancer Biology 2024

  Quote: ... rabbit PRDX2 antibody (1:2000, Proteintech, #10545-2-AP) and mouse actin antibody (1:5000 ...
• Deep Visual Proteomics Unveils Precision Medicine Insights in Composite Small Lymphocytic and Classical Hodgkin Lymphoma

  Xiang Zheng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... / anti-IRF4 antibody (1:100, 11247-2-AP, Proteintech) / anti-LENG1 antibody (1:500 ...
• Fibroblasts carrying intermediate C9orf72 hexanucleotide repeat expansions from iNPH patients show impaired energy metabolism but no cell pathologies

  Dorit Hoffmann, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-TDP-43 (1:1000, 10782-2-AP, Proteintech), anti-phospho-TDP-43 (1:1000 ...
• C9orf72 repeat expansion-carrying iPSC-microglia from FTD patients show increased phagocytic activity concomitantly with decreased number of autophagosomal-lysosomal vesicles

  Hannah Rostalski, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-TDP-43 (1:500, 10782-2-AP; Proteintech), anti-TMEM119 (1:250 ...
• C9orf72 repeat expansion-carrying iPSC-microglia from FTD patients show increased phagocytic activity concomitantly with decreased number of autophagosomal-lysosomal vesicles

  Hannah Rostalski, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-TDP-43 (1:2,000, 10782-2-AP; Proteintech). Next ...