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251 - 300 of 5774 citations for 2 Chloro 1 1 trifluoromethyl 1 3 4 9 tetrahydro 2H beta carbolin 2 yl ethan 1 one since 2020

• Fast resupply of synaptic vesicles requires Synaptotagmin-3

  Dennis J. Weingarten, et al., bioRxiv - Neuroscience 2021

  Quote: ... then in primary antibody for 2 h at RT (rabbit anti-Syt3, 1:3000, Synaptic Systems 105133; rabbit anti-Synaptophysin, 1:4000, Proteintech 17785 ...
• The Chlamydia protein CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35

  Karsten Meier, et al., bioRxiv - Microbiology 2022

  Quote: ... rabbit-anti-Rab35 (1:1000; Cell Signaling, 9690; or Proteintech, 11329-2-AP), mouse-anti-β-actin (1:2000 ...
• The TRIP6/LATS1 complex constitutes the tension sensor of α-catenin/vinculin at both bicellular and tricellular junctions

  Lin Xie, et al., bioRxiv - Cell Biology 2023

  Quote: ... CoraLite 488-conjugated Goat AntiRabbit IgG (H+L) (Proteintech, SA00013-2, 1:500), CoraLite 594-conjugated Goat AntiMouse IgG(H+L ...
• The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD

  ME Cicardi, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-TDP-43 (RRID:AB_615042, Proteintech Cat.# 10782-2-AP; IF dilution 1:500); anti-GAPDH (RRID:AB_2107436 ...
• Human Herpesvirus 8 ORF57 protein is able to reduce TDP-43 pathology: Network analysis Identifies Interacting Pathways

  Chelsea J Webber, et al., bioRxiv - Neuroscience 2023

  Quote: ... Primary antibody used was Anti-GFP (Rabbit, 1:2000, ProteinTech #50430-2-AP). Secondary antibody used was Donkey Anti-Rabbit diluted 1:10,000 in TBST.
• RNA-binding protein YBX1 promotes Type H vessels dependent bone formation in an m5C-dependent manner

  Yu-Jue Li, Qi Guo, Wen-Feng Xiao, Ye Xiao, bioRxiv - Molecular Biology 2023

  Quote: ... Primary antibodies were listed below: CD31 (66065-2-Ig, Proteintech, China, 1:1000), EMCN (sc-65495 ...
• The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4

  Femke M. Feringa, et al., bioRxiv - Neuroscience 2024

  Quote: ... The following primary antibodies were used: anti-perilipin 2 (15294-1-AP, Proteintech), anti-AQP4 (AQP-004 ...
• Coxiella burnetii-containing vacuoles interact with host recycling-endosomal proteins Rab11a and Rab35 for vacuolar expansion

  Brooke A. Hall, et al., bioRxiv - Microbiology 2024

  Quote: ... Cells were then incubated overnight at 4°C in rabbit anti-Rab35 (1:100; Cat. 11329-2-AP, Proteintech, Rosemont, IL) or for 1 h at room temperature (RT ...
• Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids

  Benjamin D. Umans, Yoav Gilad, bioRxiv - Genomics 2024

  Quote: ... Antibodies were diluted as follows in PBS with 2% NDS and 0.1% Triton X-100 for staining overnight at 4°C: HOPX (rabbit, 1:500, Proteintech, RRID AB_10693525), S100B (guinea pig ...
• Activity-Dependent Modulation of Synapse-Regulating Genes in Astrocytes

  I Farhy-Tselnicker, et al., bioRxiv - Neuroscience 2020

  Quote: ... The antibodies used were: Rb anti-Glypican 4 (Proteintech #13048-1-AP; 1:500), Rb anti IP3R2 (a gift from Ju Chen lab ...
• The radio-protective effects of (-)- Epigallocatechin-3-gallate (EGCG): regulating macrophage function in radiation-induced intestinal injury

  Jia Gu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Antibody to high mobility group box 1 (anti-HMGB1, 66525-1-Ig) and toll-like receptor 4 (anti-TLR4, 19811-1-AP) were purchased from Proteintech. Antibody to nuclear factor kappa B p65 (anti-NF-κB ...
• Integrative analysis allows a global and precise identification of functional miRNA target genes in mESCs

  Moritz Schäfer, et al., bioRxiv - Systems Biology 2021

  Quote: ... Membranes were incubated with one of the following antibodies overnight: DGCR8 antibody 1:2000 (Proteintech; 10996-1-AP), DROSHA antibody 1:2000 (Cell Signaling ...
• Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs

  Spencer Arnesen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... for 1 hour at 4°C and probed with the following antibodies overnight with shaking at 4°C: PRKD3 (Proteintech, 12785-1-AP, 1:1000 dilution), ER (Santa Cruz Biotechnology ...
• Activation of ACC synthase 2/6 increases stomatal density and cluster on the Arabidopsis leaf epidermis during drought

  Ming-zhu Jia, et al., bioRxiv - Cell Biology 2021

  Quote: ... The membrane was then incubated at room temperature for 1-2 h in blocking solution before incubation with anti-GFP mouse monoclonal antibodies (1:10,000; Proteintech, Chicago, IL, USA) for 2 h at room temperature ...
• Calcium signals tune AMPK activity and mitochondrial homeostasis in dendrites of developing neurons

  Akane Hatsuda, et al., bioRxiv - Neuroscience 2023

  Quote: ... Cells were then blocked with blocking solution (PBS with 2% BSA) and incubated with rabbit anti-AMPKα2 primary antibody (1:200, Proteintech, 18167-1-AP) at 4°C overnight ...
• 5’ UTR variants in the quantitative trait gene Hnrnph1 support reduced 5’ UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity

  Qiu T. Ruan, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 3) hnRNP H1 antibody (1:10,000, Proteintech, Rosemont, IL, USA; Cat# 14774-1-AP). The secondary used for the Bethyl and Proteintech antibodies was donkey anti-rabbit HRP (1:10,000 ...
• Human adipocyte differentiation and composition of disease-relevant lipids are regulated by miR-221-3p

  Maria A. Ahonen, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-14-3-3γ (Proteintech 12381-1-AP), anti-ACLY (Santa Cruz Biotechnology SC-517267 ...
• Biallelic Variants in MAD2L1BP (p31^comet) Cause Female Infertility Characterized by Oocyte Maturation Arrest

  Lingli Huang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Flag (1:2000, Proteintech, Cat #66008-3-Ig) and Myc (1:5000 ...
• Targeting IDH1-Mutated Oligodendroglioma with Acid Ceramidase Inhibitors

  Helena Muley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-Caspase 3 (19677-1-AP Proteintech), rabbit anti-cleaved PARP1 (ab32064 abcam) ...
• SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure

  Luming Wan, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-TNFR2 (28746-1-AP, 1:200 dilution) and anti-GAPDH (60004-4-I-Ig, 1:5,000 dilution) were purchased from Proteintech (Wuhan, China). Anti-SARS-CoV/SARS-2-S (GTX632604 ...
• TDP-43 stabilizes transcripts encoding stress granule protein G3BP1: potential relevance to ALS/FTD

  Hadjara Sidibé, et al., bioRxiv - Neuroscience 2020

  Quote: ... Blocked sections were incubated with TDP-43 antibody (1:1000, Proteintech, 10782-2-AP) at 4°C overnight ...
• Histone H3K4me3 and H3K9me3 are super over-methylated in soft tissue sarcoma compared to normal muscle in patient-derived xenograft (PDX) mouse models: an indicator of cancer methionine addiction

  Yusuke Aoki, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Horseradish-peroxidase-conjugated anti-rabbit IgG (1:20,000, SA00001-2, Proteintech, Rosemont, IL, USA) was used as a second antibody ...
• Protective role of Pten downregulation in Huntington’s Disease models

  Nisha, et al., bioRxiv - Neuroscience 2024

  Quote: ... the membranes were incubated with primary antibodies against GFP (1:10000) (Proteintech, 50430-2) and GAPDH (1:40000 ...
• ORMDL3 restrains type-I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

  Qi Zeng, et al., bioRxiv - Molecular Biology 2024

  Quote: ... myc (60003-2-Ig) HA (RM1004) HA (Ray antibody) GFP (Proteintech 66002-1-Ig) and Flag (Sigma ...
• Cold induces brain region-selective neuronal activity-dependent lipid metabolism

  Hyeonyoung Min, Yale Y Yang, Yunlei Yang, bioRxiv - Neuroscience 2024

  Quote: ... the slices were incubated with rabbit perilipin-2 antibody (1:200, CL594-15294, Proteintech) for overnight at 4 °C in the dark ...
• Senataxin and DNA-PKcs Redundantly Promote Non-Homologous End Joining Repair of DNA Double Strand Breaks During V(D)J Recombination

  Bo-Ruei Chen, et al., bioRxiv - Cell Biology 2024

  Quote: ... Antibodies to RECQL5 (12468-2-AP) and MRE11 (10744-1-AP) are from Proteintech. HA antibody (901501 ...
• TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

  Manling Xie, et al., bioRxiv - Neuroscience 2021

  Quote: ... Blots were probed with antibodies for goat anti-human TREM2 antibody, (1:1000, R&D, AF1828) and mouse anti-h-TDP-43 (1:1000, Proteintech, 60019-2-Ig).
• Annexin A1 is a polarity cue that directs planar mitotic spindle orientation during mammalian epithelial morphogenesis

  Maria Fankhaenel, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-ANXA1 (10 μg/ml, Proteintech #66344-1-Ig; 3 μg/ml, Proteintech #21990-1-AP), anti-S100A11 (10 μg/ml ...
• A CellAgeClock for expedited discovery of anti-ageing compounds

  Celia Lujan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-p16 (Proteintech, 1:500, overnight 4°C), anti-p21 (12D1 ...
• An atypical E3 ligase safeguards the ribosome during nutrient stress

  Todd Douglas, et al., bioRxiv - Cell Biology 2024

  Quote: ... 4 µg anti-PABPC1 (Proteintech 10970-1-AP) or rabbit IgG isotype control (Cell Signaling Technology 3900S ...
• Lipid Dysregulation Unveil the Intricate Interplay of Lysosomal and Mitochondrial Changes in Frontotemporal Dementia with GRN Haploinsufficiency

  Jon Ondaro, et al., bioRxiv - Neuroscience 2024

  Quote: ... PINK1 (1:1 000, BC100-494, Novus Bio) TOM20 (1:1 000, 11802-1-AP, Proteintech), GAPDH (1:50 000 ...
• The T-type voltage-gated Ca²⁺ channel Ca_V3.1 as a candidate receptor for Pasteurella multocida toxin and contributes to the disruption of respiratory epithelial barrier induced by the toxin

  Haixin Bi, et al., bioRxiv - Microbiology 2024

  Quote: ... the cells were incubated overnight at 4°C with ZO-1 antibody (1:500, catalog no. 21773-1-AP; Proteintech, Wuhan, China). After washing ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... cofilin-1 (1:1000, Proteintech, #66057-1-Ig), GRIA1 (1:1000 ...
• Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress

  José M. Liboy-Lugo, et al., bioRxiv - Cell Biology 2024

  Quote: ... Caprin-1 (Proteintech, 15112-1-AP, 1:1000), β-actin (Abcam ...
• rtPA Directly Protects Neurons After Intracerebral Hemorrhage through PI3K/AKT/mTOR Pathway

  Jie Jing, et al., bioRxiv - Neuroscience 2023

  Quote: ... Beclin-1 (Proteintech, 11306-1-AP, 1:1000), SQSTM1/p62 (Abclonal ...
• Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin

  Stephanie L. Baringer, et al., bioRxiv - Neuroscience 2023

  Quote: ... NEP-1 (ProteinTech, 18008-1-AP, 1:1000), APP (ProteinTech ...
• Chaperones Hsc70 and Hsp70 Play Distinct Roles in Bocaparvovirus Minute Virus of Canines Infection

  Jianhui Guo, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Flag (66008-3-Ig; Proteintech; WB: 1:1000; IP: 3 μg), anti-GAPDH (TA-08 ...
• Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topology

  Ying Zhu, et al., bioRxiv - Systems Biology 2022

  Quote: ... anti-TIMM44 and TOMM70 (1:500, 1:1000, 1:500, rabbit, ProteinTech, 16139-1-AP, 13859-1-AP, 14528-1-AP); anti-TIMM23 (1:1000 ...
• Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages

  Eric Yau, et al., bioRxiv - Immunology 2021

  Quote: ... Blots were probed at 4°C overnight with MYO18A (Proteintech Cat#14611-1-AP, 1:1000), p-IRF3 Ser396 (Cell Signaling Technology Cat#29047 ...
• Ca²⁺-driven PDIA6 phase separation to ensure proinsulin quality control

  Young-Ho Lee, et al., bioRxiv - Biochemistry 2024

  Quote: ... mCherry (1:1000; Proteintech, 26765-1-AP, 1:1000; Proteintech, 68088-1-Ig) and GRP78 BiP (1:1000 ...
• Anal skin-like epithelium mediates colonic wound healing

  Cambrian Y. Liu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-TGM1 (Proteintech 12912-3-AP, 1:500), rabbit anti-KRT1 (Biolegend 905602 ...
• SUMOylation- and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization

  D.E. MacNeil, et al., bioRxiv - Cell Biology 2020

  Quote: ... or anti-FLAG (Proteintech, 66008-3-Ig, 1:4000), anti-NAF1 (Abcam ...
• The Primary Cilium and its Hedgehog Signaling in Nociceptors Contribute to Inflammatory and Neuropathic Pain

  Lindsey A. Fitzsimons, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse NeuN (RNA binding fox-1 homolog 3; ProteinTech) 1:1000 ...
• The 21-base pair deletion mutant Calpain 3 does not inhibit wild-type Calpain 3 activity

  Swati Maitra, et al., bioRxiv - Cell Biology 2023

  Quote: ... Calpain 3 (Proteintech and Santa Cruz Biotechnology, 1:1000), Calpastatin (Proteintech and Santa Cruz Biotechnology ...
• Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2

  Guoli Shi, et al., bioRxiv - Microbiology 2022

  Quote: ... stained with anti-IFITM2/3 (66081-1-Ig; Proteintech), goat anti-mouse IgG Alexa Fluor 647 (A21235 ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-flag (1:5000; Cat# 66008-3-Ig, Proteintech) antibody ...
• SIRT1 ameliorates premature senescence-induced defenestration in hepatic sinusoidal endothelial cell

  Xiaoying Luo, et al., bioRxiv - Cell Biology 2020

  Quote: ... and HRP-conjugated Affinipure Goat Anti-Rabbit IgG(H+L) (1:10000, Proteintech, SA00001-2). The protein bands were visualized using the Pierce(tm ...
• A programmable system to methylate and demethylate m⁶A on specific mRNAs

  Chen Chang, et al., bioRxiv - Cell Biology 2021

  Quote: ... or HRP-conjugated Affinipure Goat Anti-Rabbit IgG(H+L) (1:5000, SA00001-2, Proteintech) and ECL prime substrate (Bio-Rad ...
• Amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex

  MS Dyer, et al., bioRxiv - Neuroscience 2020

  Quote: ... and a rabbit α-TDP-43 antibody (1:1000; Proteintech, Cat#: 10782-2-AP (2018)) overnight in PBS with 0.3% triton-X ...
• In vivo CGG repeat RNA binding protein capture identifies RAN translation modifiers and suppressors of repeat toxicity

  Indranil Malik, et al., bioRxiv - Neuroscience 2021

  Quote: ... Cells were stained with primary antibody SRSF1 (1:100, rabbit from Proteintech, 12929-2-AP) overnight at 4°C then followed by 3 times of 5 min 1x PBS washes before staining with secondary antibody (1:500 ...