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2051 - 2100 of 5738 citations for 3 Methyl 1 6 naphthyridine 2 carboximidamide hydrochloride since 2020

• Mechanistic basis of gene-specific transcription regulation by the Integrator complex

  Kevin Sabath, et al., bioRxiv - Molecular Biology 2024

  Quote: ... mouse anti-V5-tag (Proteintech Group, 66007-1-Ig, 1:5,000), mouse anti-β-actin (Proteintech Group ...
• Mechanistic basis of gene-specific transcription regulation by the Integrator complex

  Kevin Sabath, et al., bioRxiv - Molecular Biology 2024

  Quote: ... mouse anti-β-actin (Proteintech Group, 60008-1-Ig, 1:20,000) horseradish peroxidase-linked anti-mouse IgG (Sigma-Aldrich ...
• Fibronectin 1 is a novel biomarker of obstetric antiphospholipid syndrome

  Jinfeng Xu, et al., bioRxiv - Developmental Biology 2024

  Quote: ... The primary antibody of FN1 (1:1000, 15613-1-AP, Proteintech) was used ...
• Interactors of sacsin’s DNAJ domain identify function in organellar transport and membrane composition relevant to ARSACS pathogenesis

  Alexandre M. Paré, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit polyclonal anti-endophilinB2 (15897-1-AP, Proteintech, USA, 1:400), rabbit polyclonal anti-ARF5 (clone 9E10 ...
• Interactors of sacsin’s DNAJ domain identify function in organellar transport and membrane composition relevant to ARSACS pathogenesis

  Alexandre M. Paré, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-Rab1b antibody (Cat # 17824-1-AP Proteintech 1:1000).
• Caspase cleavage of Influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production

  Carmen Figueras-Novoa, et al., bioRxiv - Microbiology 2024

  Quote: ... mouse monoclonal anti-β-actin (Proteintech, 66009-1, WB 1:10000), rabbit polyclonal anti-IAV NP (GeneTex ...
• Defining the mechanisms and properties of post-transcriptional regulatory disordered regions by high-throughput functional profiling

  Joseph H. Lobel, Nicholas T. Ingolia, bioRxiv - Genomics 2024

  Quote: ... or 1:10000 GAPDH as a loading control (Proteintech 60004-1). Blots were developed with SuperSignal West Dura Extended Duration Substrate (Thermo Scientific 34075 ...
• Human CCDC51 and yeast Mdm33 are functionally conserved mitochondrial inner membrane proteins that demarcate a subset of organelle fission events

  Alia R. Edington, et al., bioRxiv - Cell Biology 2024

  Quote: ... where indicated: rabbit anti- CCDC51 (1:2500; Proteintech; 20465-1-AP), mouse anti-GAPDH (1:2500 ...
• Reduced nephron endowment in the common Six2-TGC^tg mouse line is due to Six3 misexpression by aberrant enhancer-promoter interactions in the transgene

  Alison J. Perl, et al., bioRxiv - Developmental Biology 2023

  Quote: ... for western blot: anti-Six2 (1:500, 11562-1-AP, Proteintech) and (OriGene ...
• Mitochondrial One-Carbon Metabolism is Required for TGF-β-Induced Glycine Synthesis and Collagen Protein Production

  Angelo Y. Meliton, et al., bioRxiv - Cell Biology 2023

  Quote: ... Rabbit polyclonal anti-MTHFD2 antibody (Proteintech, 12270-1-AP, 1:400) was applied on tissue sections for a 1-h incubation at room temperature in a humidity chamber ...
• ISG15/USP18/STAT2 is a molecular hub regulating autocrine IFN I-mediated control of Dengue and Zika virus replication

  Constanza Eleonora Espada, et al., bioRxiv - Immunology 2023

  Quote: ... rabbit pAb to IFIT3 (ProteinTech, 15201-1-AP, dilution 1:1000), rabbit mAb to USP18 [D4E7] (Cell Signalling Technologies ...
• Mechanical cues of extracellular matrix determine tumor innervation

  Shu-Heng Jiang, et al., bioRxiv - Neuroscience 2024

  Quote: ... PGP9.5 (66230-1-Ig, Proteintech, 1:500; for co-IF analysis), CK19 (1:200 ...
• Protein disulfide isomerase disassembles stress granules and blocks cytoplasmic aggregation of TDP-43 in ALS

  Jia-Qi Liu, et al., bioRxiv - Biochemistry 2024

  Quote: ... mouse anti-G3BP1 monoclonal antibody (Proteintech, 66486-1-Ig, 1:5000), rabbit anti-phospho-TDP-43 (pS409/410 ...
• The V-ATPase/ATG16L1 axis is controlled by the V₁H subunit

  Lewis Timimi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit polyclonal anti-GABARAPL1 (Proteintech, 11010-1-AP, WB 1:1000), mouse monoclonal anti-IAV matrix 2 (Abcam ...
• The V-ATPase/ATG16L1 axis is controlled by the V₁H subunit

  Lewis Timimi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit polyclonal anti-ATP6V1H (Proteintech, 26683-1-AP, WB 1:1000), rabbit polyclonal anti-ATP6V0A1 (Proteintech ...
• The V-ATPase/ATG16L1 axis is controlled by the V₁H subunit

  Lewis Timimi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse monoclonal anti-β-actin (Proteintech, 66009-1, WB 1:10000), rabbit monoclonal anti-ATP6V1A (Abcam ...
• Proximity Labeling Expansion Microscopy (PL-ExM) resolves structure of the interactome

  Sohyeon Park, et al., bioRxiv - Bioengineering 2023

  Quote: ... Rabbit x ARL 13B (1:100 dilution, Proteintech; 17711-1-AP), Mouse x CEP164 (1:100 dilution ...
• TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and -independent mechanisms without relying on heme and FBXO22

  Liang Liu, et al., bioRxiv - Biochemistry 2024

  Quote: ... rabbit anti-FBXO22 (1:1000, 13606-1-AP, Proteintech, Rosemont, IL), mouse anti-DDDDK-tag (1:1000 ...
• Genome-scale mapping of DNA damage suppressors identifies GNB1L as essential for ATM and ATR biogenesis

  Yichao Zhao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-TELO2 (1:1500 for IB; Proteintech, 15975-1-AP), rabbit anti-TTI1 (1:3000 for IB ...
• Genome-scale mapping of DNA damage suppressors identifies GNB1L as essential for ATM and ATR biogenesis

  Yichao Zhao, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-PIH1D1 (1:1000 for IB; Proteintech, 19427-1-AP), rabbit anti-RPAP3 (1:1000 for IB ...
• Spread of pathological human Tau from neurons to oligodendrocytes and loss of high-firing pyramidal neurons in ageing mice

  Tim J. Viney, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Wfs1 1:1000 (11558-1-AP, lot 00043335, Proteintech). Specificity references can be found in the following publications ...
• Comparative multi-omics analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency

  Nicole M. Sayles, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and polyclonal rabbit-anti-frataxin (1:1000; ProteinTech; 14147-1-AP).
• An extra-circadian function for human CLOCK in the neocortex

  Yuxiang Liu, et al., bioRxiv - Neuroscience 2023

  Quote: ... We used rabbit anti-CUX1 (1:200; Proteintech, #11733-1-AP) to label layers 2-4 ...
• Rsp5/NEDD4 and ESCRT regulate TDP-43 toxicity and turnover via an endolysosomal clearance mechanism

  Aaron Byrd, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-NEDD4 (catalog number 21698-1-AP; Proteintech; dilution 1:1000), anti-Ubiquitin (catalog number sc-8017 ...
• Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion

  Matthew J. White, et al., bioRxiv - Cell Biology 2023

  Quote: ... Lamin B1 antibody (12987-1-AP, 1:1000) was from Proteintech. Rhodamine phalloidin and Alexa Fluor 488 ...
• PKR-mediated Stress Response Enhances Dengue and Zika Virus Replication

  Taissa Ricciardi-Jorge, et al., bioRxiv - Immunology 2023

  Quote: ... GADD34 antibody (Proteintech, 10449-1-AP, dilution 1:250 (IF/FACS); Zombie-NIR fixable viability dye (BioLegend ...
• Human Herpesvirus 8 ORF57 protein is able to reduce TDP-43 pathology: Network analysis Identifies Interacting Pathways

  Chelsea J Webber, et al., bioRxiv - Neuroscience 2023

  Quote: ... Anti-TDP43 C-terminus (Rabbit, 1:1000, ProteinTech #12892-1-AP), Anti-G3BP1 (Mouse ...
• Differentiation of Large Extracellular Vesicles in Oral Fluid: Combined Protocol of Small Force Centrifugation and Pattern Analysis

  Takamasa Kawano, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-CD81 (66866-1-Ig, Proteintech, Rosemont, USA; 1:1000), goat anti-rabbit IgG (H + L)-HRP conjugate (170-6515 ...
• Small extracellular vesicles from young adipose-derived stem cells ameliorate age-related changes in the heart of old mice

  Jorge Sanz-Ros, et al., bioRxiv - Physiology 2024

  Quote: ... LMNB1 staining: anti-LMNB1 (Proteintech, 12987-1-AP; 1:50 dilution) and Alexa Fluor 488 anti-rabbit (Abcam ...
• Small extracellular vesicles from young adipose-derived stem cells ameliorate age-related changes in the heart of old mice

  Jorge Sanz-Ros, et al., bioRxiv - Physiology 2024

  Quote: CD3 staining: anti-CD3 (Proteintech, 17617-1-AP; 1:1000 dilution) and Alexa Fluor 647 anti-rabbit (Abcam ...
• Mitoregulin supports mitochondrial membrane integrity and protects against cardiac ischemia-reperfusion injury

  Colleen S. Stein, et al., bioRxiv - Cell Biology 2024

  Quote: ... Primary antibodies were: anti-Mtln (1/2000–1/3000, custom Proteintech specific Mtln c-terminal amino acids 38-56)1 ...
• mTOR dysregulation induces IL6 and paracrine AT2 cell senescence impeding lung repair in lymphangioleiomyomatosis

  Roya Babaei-Jadidi, et al., bioRxiv - Cell Biology 2024

  Quote: ... P16INK4A Rabbit Polyclonal antibody (1:500, Proteintech No. 10883-1-AP), p21Waf1/Cip1 (12D1 ...
• Porphyromonas gingivalis activates Heat-Shock-Protein 27 to drive a LC3C-specific probacterial form of select autophagy that is redox sensitive for intracellular bacterial survival in human gingival mucosa

  Bridgette Wellslager, et al., bioRxiv - Microbiology 2024

  Quote: ... or anti-LC3C rabbit antibody (ProteinTech, 18726-1-AP: 1:500). After primary antibody incubation ...
• Multi-omic Analysis Identifies Glioblastoma Dependency on H3K9me3 Methyltransferase Activity

  Qiqi Xie, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and anti-α-Tubulin (Proteintech, Cat# 11224-1-AP, 1:4000).
• Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

  Sachin N. Davis, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-PAX8 (1:250, 10336-1-AP, Proteintech, RRID: AB_2236705), rabbit anti-LEF1 (1:300 ...
• Dynamic Electrical Stimulation Promotes hiPSC-CM Differentiation and Functionality

  Nikhith Kalkunte, et al., bioRxiv - Bioengineering 2024

  Quote: ... including cardiac troponin T (cTnT; 1:500, Proteintech, 15513-1-AP) and Octamer-binding transcription factor 4 (OCT-4 ...
• Glycosaminoglycan-mediated lipoprotein uptake protects cancer cells from ferroptosis

  Dylan Calhoon, et al., bioRxiv - Cancer Biology 2024

  Quote: ... AIFM2 (20866-1-AP) and PAPSS1 (14708-1-AP) from ProteinTech; mouse GPX4 (sc-166570 ...
• AAV-mediated gene transfer of WDR45 corrects neurologic deficits in the mouse model of beta-propeller protein-associated neurodegeneration

  Maria Carla Carisi, et al., bioRxiv - Neuroscience 2024

  Quote: ... αWIPI4/WDR45 1:2000 (rabbit, Proteintech, Rosemont, IL, 19194-1-AP), αLC3B 1:500 (rabbit ...
• Targeting protein tyrosine phosphatase non-receptor type 2 with a novel inhibitor for AML therapy

  Wenbin Kuang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... XIAP rabbit polyclonal antibody (Proteintech, Cat#: 10037-1-Ig, 1:1000), C-MYC rabbit polyclonal antibody (Proteintech ...
• Targeting protein tyrosine phosphatase non-receptor type 2 with a novel inhibitor for AML therapy

  Wenbin Kuang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Vinculin rabbit polyclonal antibody (Proteintech, Cat#: 26520-1-AP, 1:1000), Alpha Tubulin mouse monoclonal antibody (Proteintech ...
• Targeting protein tyrosine phosphatase non-receptor type 2 with a novel inhibitor for AML therapy

  Wenbin Kuang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... P21 rabbit polyclonal antibody (Proteintech, Cat#: 10355-1-AP, 1:1000), P27 rabbit monoclonal antibody (Cell Signaling Technology ...
• Identification of Glucosidase II that regulates STIM1 activation dynamics

  Yangchun Du, et al., bioRxiv - Cell Biology 2024

  Quote: ... and anti-UGGT1 antibody (Proteintech, Cat:14170-1-AP; 1:1000) followed by anti-rabbit-IgG (7074S ...
• Goal-Directed Learning in Cortical Organoids

  Ash Robbins, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti Map2 (Proteintech #17490-1-AP, RRID: AB_2137880, 1:2000); mouse anti Sst (Santa Cruz Biotechnology #sc-55565 ...
• Fate plasticity of interneuron specification

  Mohammed A. Mostajo-Radji, et al., bioRxiv - Neuroscience 2024

  Quote: Rabbit anti-Gbx2 (Proteintech # 21639-1-AP; RRID: AB_2878896; 1:250)
• FcγR- and CD9-dependent synapse engulfing microglia in the thalamus drives cognitive impairment following cortical brain injury

  Ken Matoba, et al., bioRxiv - Immunology 2024

  Quote: ... and rabbit polyclonal anti-Ifitm3 (1:100; Proteintech, #11714-1-AP).
• Recruitment of the cellular lipid transport protein CERT to C. psittaci inclusions regulates the timing of bacterial egress

  Jana Scholz, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-STIM1 (1:50, Cat. No. 11565-1-AP, Proteintech), Alexa Fluor 488-coupled goat anti-rabbit IgG (1:100 ...
• Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6

  Taha Y. Taha, et al., bioRxiv - Microbiology 2024

  Quote: ... and monoclonal mouse-anti-GAPDH (ProteinTech, 60004-1-Ig, 1:5000).
• Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism

  Mengyun Li, et al., bioRxiv - Immunology 2024

  Quote: ... anti-Phospho FOXO3 (Ser315) (1:500, Cat# 28755-1-AP, Proteintech), anti-AKT (1:1000 ...
• The UFMylation pathway is impaired in Alzheimer’s disease

  Tingxiang Yan, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-UFM1-Ab3 (Proteintech Group, 15883-1-AP, 1:100), rabbit anti-UFM1-Ab4 (LS Bio ...
• The UFMylation pathway is impaired in Alzheimer’s disease

  Tingxiang Yan, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-UFM1-Ab3 (Proteintech Group, 15883-1-AP, 1:1000), rabbit anti-UFM1-Ab4 (LS Bio ...