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1351 - 1400 of 5305 citations for 7 CHLORO 2H PYRIDO 3 2 B 1 4 OXAZIN 3 4H ONE since 2019

• Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome

  Na Xiao, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-c-Myc (1:2000, 10828-1-AP, Proteintech), anti-HIF-1α (5ug/ml ...
• TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

  Manling Xie, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-CNPase (1:500, Proteintech, 13427-1-AP), rabbit anti-TMEM119 (1:500 ...
• The RNA helicases DDX5 and DDX17 facilitate neural differentiation of human pluripotent stem cells NTERA2

  Praewa Suthapot, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-DDX17 (Proteintech, 19910-1-AP, 1:3,000 dilution), anti-OCT4 (Invitrogen ...
• Role of PARP1 in oligodendrocyte differentiation during developmental myelination and remyelination after myelin damage

  Yan Wang, et al., bioRxiv - Neuroscience 2021

  Quote: ... TLE3 (1:1000, #11372-1-AP, RRID: AB_2203743, Proteintech), AIF (1:1000 ...
• Role of PARP1 in oligodendrocyte differentiation during developmental myelination and remyelination after myelin damage

  Yan Wang, et al., bioRxiv - Neuroscience 2021

  Quote: ... Myef2 (1:100, 16051-1-AP, RRID: AB_2146869, Proteintech), SMI312 (1:100 ...
• Role of PARP1 in oligodendrocyte differentiation during developmental myelination and remyelination after myelin damage

  Yan Wang, et al., bioRxiv - Neuroscience 2021

  Quote: ... Myef2 (1:100, 16051-1-AP, RRID: AB_2146869, Proteintech), MBP (1:100 ...
• Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma

  Allison N. Lau, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or ME1 (Proteintech 16619-1-AP, 1:200 dilution). The human pancreatic cancer tissue microarray was scored independently by a pathologist (O.H.Y.) ...
• Eukaryotic translation initiation factor 2A protects pancreatic beta cells during endoplasmic reticulum stress while rescuing translation inhibition

  Evgeniy Panzhinskiy, et al., bioRxiv - Physiology 2021

  Quote: ... and EIF2A (1:1000, Cat. # 11233-1-AP, ProteinTech), EIF2D (1:1000 ...
• MiR-384 Regulates Reelin by Inhibiting ADAMTS4 in Neuronal Cell Lines

  Qiushi Cao, et al., bioRxiv - Biochemistry 2021

  Quote: ... and anti-pAkt (66444-1-Ig, Proteintech 1:800), respectively ...
• Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

  Fei Li, et al., bioRxiv - Microbiology 2020

  Quote: ... and anti-ACE2 (Proteintech, 21115-1-AP, 1:1000) antibodies.
• Interplay of the Trypanosome Lytic Factor and innate immune cells in the resolution of cutaneous Leishmania infection

  Jyoti Pant, et al., bioRxiv - Microbiology 2020

  Quote: ... followed by anti-mouse (1:10,000, Proteintech, SA00001-1) secondary antibody and detected by chemiluminescence.
• A rare variant in ANP32B impairs influenza virus replication in human cells

  Ecco Staller, et al., bioRxiv - Microbiology 2020

  Quote: ... rabbit α-ANP32B (10843-1-AP, 1/1,000; Proteintech), mouse α-FLAG (catalogue number F1804 ...
• Chicoric acid prevents neurodegeneration via microbiota-gut-brain axis in a mouse Parkinson’s disease model

  Ning Wang, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-TLR4 (1:1000, 19811-1-AP, Proteintech), rabbit anti-NF-κB (1:1000 ...
• Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs

  Carlo Brighi, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-TBR1 (20932-1-AP Proteintech, 1:150), rabbit anti-β-TUBULIN III (TUJ1 ...
• A co-opted endogenous retroviral envelope promotes cell survival by controlling SLC31A1/CTR1-mediated copper transport and homeostasis

  Sandrine Tury, et al., bioRxiv - Microbiology 2021

  Quote: ... or CTR1 monoclonal antibody (Proteintech, 67221-1, 1:1000) followed by horseradish peroxidase (HRP)-conjugated anti-mouse antibodies (Jackson ...
• The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo

  Bressan Cedric, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-p62 (1:500, Proteintech, #18420-1-AP, RRID:AB_10694431), anti-paxillin (1:1000 ...
• Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy

  Emma V. Rusilowicz-Jones, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-actin (ProteinTech 66009-1-Ig, 1:10,000) anti-phospho-Ubiquitin Ser65 (Millipore ...
• Tubular ERGIC (t-ERGIC): a SURF4-mediated expressway for ER-to-Golgi transport

  Rui Yan, Kun Chen, Ke Xu, bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-Rab1B (Proteintech 17824-1-AP, 1:40), mouse anti-DsRed (Santa Cruz 390909 ...
• Tubular ERGIC (t-ERGIC): a SURF4-mediated expressway for ER-to-Golgi transport

  Rui Yan, Kun Chen, Ke Xu, bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-Sec31A (Proteintech 17913-1-AP, 1:200), mouse anti-calumenin (Santa Cruz 271357 ...
• Mitochondrial energy dysfunction induces remodeling of the cardiac mitochondrial protein acylome

  Jessica N. Peoples, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-α-tubulin (Proteintech 11224-1-AP, 1:1000) and anti-GAPDH (Fitzgerald ...
• Differentiation of ciliated human midbrain-derived LUHMES neurons

  Gilbert Lauter, et al., bioRxiv - Neuroscience 2020

  Quote: ... and IFT88 (rabbit, ProteinTech 13967-1-AP, 1:500). Neuronal differentiation markers were TUBB3 (Tuj1 ...
• MICAL2 acts through Arp3B isoform-specific Arp2/3 complexes to destabilize branched actin networks

  Chiara Galloni, et al., bioRxiv - Cell Biology 2020

  Quote: ... MICAL1 polyclonal (Proteintech, 14818-1-AP, 1:1000 dilution), GFP monoclonal (custom made by CRUK ...
• A novel USP30 inhibitor recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation

  Emma Rusilowicz-Jones, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit-anti-actin (ProteinTech,20536-1-AP, 1:10,000), anti-SYNJ2BP (Sigma HPA000866 ...
• CiliaQ – a simple, open-source software for automated quantification of ciliary morphology and fluorescence in 2D, 3D, and 4D images

  Jan Niklas Hansen, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-ARL13B (1:500, Proteintech, 17711-1-AP), mouse anti-ARL13B (Abcam ...
• Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms

  Francois Iv, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-SEPT9 (1:1,500, Proteintech, 10769-1-AP), and HRP-conjugated anti-rabbit antibody (1:10,000 ...
• The crosstalk between DNA-PK and cGAS drives tumor immunogenicity

  Clara Taffoni, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-GAPDH (60004-1-Ig, Proteintech Europe, 1:5000), anti-αTUBULIN (66031-1-Ig ...
• The crosstalk between DNA-PK and cGAS drives tumor immunogenicity

  Clara Taffoni, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-αTUBULIN (66031-1-Ig, Proteintech Europe, 1:10000). Membranes were incubated with secondary antibodies (Cell Signaling Technology ...
• Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis

  Vaibhav Sidarala, et al., bioRxiv - Cell Biology 2022

  Quote: ... mt-Cytb (1:500; ProteinTech, Catalog# 55090-1-AP), Opa1 (1:1000 ...
• The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells

  A.F.J. Janssen, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-emerin (Proteintech, 10351-1-AP, 1/500), mouse anti-lamin B1 (Santa Cruz ...
• The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells

  A.F.J. Janssen, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-emerin (Proteintech, #10351-1-AP, 1/1000), rabbit anti-H3K9me3 (Abcam ...
• Human septins in cells organize as octamer-based filaments mediating actin-membrane anchoring

  Carla Silva Martins, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-SEPT9 (1:200, Proteintech 10769-1-AP), mouse anti-α-tubulin (1:10,000 ...
• Newly raised anti-c-Kit antibody detects interstitial cells of Cajal in the gut of chicken embryos

  Rei Yagasaki, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 1:500 dilution of Tuj1 (Proteintech, 66375-1-Ig) overnight at 4 °C ...
• Develop an efficient and specific AAV based labeling system for Muller glia in mice

  Yanxia Gao, et al., bioRxiv - Neuroscience 2022

  Quote: ... Rabbit-anti-Calbindin (1:200, Proteintech, 14479-1-AP) and mouse-anti-Calretinin (1:200 ...
• Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair

  Justinn Barr, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Gnb3 (1:200, 10081-1-AP, Proteintech), rabbit anti-POU2F3 (1:500 ...
• Pancreatic tumors activate arginine biosynthesis to adapt to myeloid-driven amino acid stress

  Juan J. Apiz-Saab, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Beta-Actin (Proteintech 660009-1-lg; 1:10000 dilution). The following secondary antibodies ...
• Vitamin C functions as double-edge sword on cancer progression depending on ERK activation or inhibition mediated by its receptor SVCT2

  Yian Guan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-GFP (1:1000, Cat#66002-1-Ig, Proteintech), anti-HA (1:1000 ...
• A conditional null allele of Dync1h1 enables targeted analyses of dynein roles in neuronal length sensing and neurological disorders

  Agostina Di Pizio, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-dync1h1 (Proteintech, 12345-1-AP, 1:500), mouse anti-Importin β1 (monoclonal ...
• A murine Wac model exhibits phenotypes relevant to DeSanto-Shinawi Syndrome

  April M Stafford, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-S100beta (1:500, 15146-1-AP Proteintech), rat anti-SST (1:200 ...
• Develop an efficient and specific AAV based labeling system for Muller glia in mice

  Yanxia Gao, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Pax6 (1:200, Proteintech, 12323-1-AP). Sections were washed 3x for 10 minutes per wash on the second day ...
• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and Lamin B1 (1/1000, Proteintech, #12987-1-AP). Blots validating SILAC results and lamin response to Akt inhibition were conducted as above ...
• Biochemical analysis challenging Western blot analysis as validation step for antibodies intended for ELISA and Immunohistochemistry use

  Yunyun Zhang, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-PYGL-1 (rabbit polyclonal, 15851-1-AP, Proteintech, RRID ...
• Piezo mechanosensory channels regulate centrosome integrity

  Liron David, et al., bioRxiv - Cell Biology 2022

  Quote: ... GAPDH mouse monoclonal antibody (1:5000, Proteintech 60004-1) at 4 °C ...
• The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic Hedgehog signalling

  Leah Schembs, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-SMO (1:600; Proteintech #20787-1-AP), rabbit anti-SOX2 (1:1000 ...
• The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic Hedgehog signalling

  Leah Schembs, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-TMEM67 (1:200; Proteintech #13975-1-AP), mouse anti-γ TUB (Sigma T6557 ...
• The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic Hedgehog signalling

  Leah Schembs, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-SUFU (1:600; Proteintech #26759-1-AP), rabbit anti-TBR1 (1:400 ...
• The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic Hedgehog signalling

  Leah Schembs, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-TULP3 (1:600; Proteintech #13637-1-AP). Primary antibodies for immunohistochemistry were detected with Alexa- or Cy2/3-conjugated fluorescent secondary antibodies ...
• Self-activation of Wnt signaling in pre-granulosa cells is required for ovarian folliculogenesis

  Okiko Habara, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-Cyp17a1 (1:4,000, 14447-1-AP, Proteintech), rat anti-Pecam1 (1:100 ...
• Hypusinated eIF5A is required for the translation of collagen

  Marina Barba-Aliaga, et al., bioRxiv - Molecular Biology 2021

  Quote: ... α-tubulin (1:5000, Proteintech Cat# 66031-1-Ig, RRID:AB_11042766), or GAPDH (mouse monoclonal anti-GAPDH antibody ...
• A novel USP30 inhibitor recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation

  Emma Rusilowicz-Jones, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-actin (ProteinTech 66009-1-Ig, 1:10,000), rabbit-anti-actin (ProteinTech,20536-1-AP ...
• Inhibition of arenavirus entry and replication by the cell-intrinsic restriction factor ZMPSTE24 is enhanced by IFITM antiviral activity

  Robert J Stott, Toshana L Foster, bioRxiv - Microbiology 2021

  Quote: ... rabbit anti-IFITM3 (Proteintech, 11714-1-AP, 1:5000), rabbit anti-ZMPSTE24 antibody (Abcam ab38450 ...