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801 - 850 of 5749 citations for 1 5 Bromo 1 2 Trimethylsilyl Ethoxy Methyl 1H Pyrrolo 2 3 B Pyridin 3 Yl Ethanone since 2020

• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... MRPL4 (Proteintech, 27484-1-AP, 1:1000), MRPS16 (Proteintech ...
• Tau tubulin kinase 1 and 2 regulate ciliogenesis and human pluripotent stem cells–derived neural rosettes

  Lucia Binó, Lukáš Čajánek, bioRxiv - Cell Biology 2023

  Quote: ... α-TUBULIN (mouse, 6631-1 Proteintech, 1:2000) was used as a loading control ...
• eIF2B localisation and its regulation during the integrated stress response is cell type specific

  Filipe M. Hanson, et al., bioRxiv - Cell Biology 2023

  Quote: ... eIF2Bβ (1:25, 11034-1-AP, Proteintech), eIF2Bγ (1:50 ...
• Pathway choice in the alternative telomere lengthening in neoplasia is dictated by replication fork processing mediated by EXD2’s nuclease activity

  Ronan Broderick, et al., bioRxiv - Molecular Biology 2023

  Quote: ... RAD52 (28045-1-AP, Proteintech, 1:2000), SMARCAL1 (Santa Cruz ...
• The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in colon cancer cells

  Věra Slaninová, et al., bioRxiv - Cancer Biology 2023

  Quote: P53 (1/5000; Proteintech #10442-1-AP)
• A protein hydroxylase couples epithelial membrane biology to nucleolar ribosome biogenesis

  Eline Hendrix, et al., bioRxiv - Cell Biology 2023

  Quote: ... LIN7C (Proteintech, 14656-1-AP, 1:1000), MINA (DSHB ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (Proteintech, 60004-1-Ig, 1:5000), EF-2 (Santa Cruz Biotechnology ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... HSP90 (Proteintech, 13171-1-AP, 1:2000), GAPDH (Proteintech ...
• SPTF-3/SP1 orchestrates mitochondrial biogenesis upon ribosomal stress and acute starvation

  Johannes CW Hemerling, et al., bioRxiv - Molecular Biology 2023

  Quote: ... NUO-1 (NDUFV1, Proteintech, #11238-1-AP), PGC-1α (Santa Cruz ...
• YAP and TAZ differentially regulate postnatal cortical progenitor proliferation and astrocyte differentiation

  Jessie Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... S100β (Proteintech 14146-1-AP, 1:500), GFAP (abcam 4674 ...
• TPPP Forms Liquid Condensates and Aggregates in Multiple System Atrophy

  Shahrnaz Kemal, et al., bioRxiv - Neuroscience 2023

  Quote: ... GAPDH (Proteintech 60004-1-Ig, 1:50,000), and TPPP (ThermoFisher PA5-19243 ...
• Aberrant activation of the innate immune sensor PKR by self dsRNA is prevented by direct interaction with ADAR1

  Ketty Sinigaglia, et al., bioRxiv - Immunology 2023

  Quote: ... Gapdh 1:20,000 (Proteintech, #60004-1-Ig). Adar1 1:3000 (to detect human ADAR ...
• Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis

  Emily Jean Wilson, et al., bioRxiv - Pathology 2023

  Quote: ... anti-claudin 1 (Proteintech, 13050-1-AP); anti-occludin (Proteintech ...
• Mechanistic insights into the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control

  Ryosuke Ishimura, et al., bioRxiv - Biochemistry 2023

  Quote: ... UFBP1 (21445-1-AP, Proteintech; 1:1000), CDK5RAP (H00080279-M01 ...
• Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway

  Iqbal Dulloo, et al., bioRxiv - Cell Biology 2022

  Quote: ... SPCS1 (Proteintech, #11847-1-AP; 1:500), SPCS2 (Merck Life Science ...
• Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway

  Iqbal Dulloo, et al., bioRxiv - Cell Biology 2022

  Quote: ... SEC11A (Proteintech, #14753-1-AP; 1:500), SEC11C (Novus Biologicals ...
• eIF2B localisation and its regulation during the integrated stress response is cell type specific

  Filipe M. Hanson, et al., bioRxiv - Cell Biology 2023

  Quote: ... PERK (1:1000, 20582-1-AP, Proteintech), GADD34 (1:500 ...
• eIF2B localisation and its regulation during the integrated stress response is cell type specific

  Filipe M. Hanson, et al., bioRxiv - Cell Biology 2023

  Quote: ... CHOP (1:1000, 15204-1-AP, Proteintech), ATF4 (1:750 ...
• eIF2B localisation and its regulation during the integrated stress response is cell type specific

  Filipe M. Hanson, et al., bioRxiv - Cell Biology 2023

  Quote: ... GADD34 (1:500, 10449-1-AP, Proteintech), CHOP (1:1000 ...
• Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy

  Elena Marchesan, et al., bioRxiv - Cell Biology 2023

  Quote: ... Mfn1 (1:600; Proteintech; 13798-1-AP) Parkin (1:1000 ...
• Cell division tracing combined with single-cell transcriptomics reveals new cell types and differentiation paths in the regenerating mouse lung

  Leila R. Martins, et al., bioRxiv - Cell Biology 2023

  Quote: ... Agr2 (1:100, #12275-1-AP, Proteintech), CC10 (1:500 ...
• Multi-omics analysis identifies RFX7 targets involved in tumor suppression and neuronal processes

  Katjana Schwab, et al., bioRxiv - Genomics 2022

  Quote: ... PIK3IP1 (1:500; #16826-1-AP, Proteintech).
• Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

  Mary E. Mohr, et al., bioRxiv - Cell Biology 2023

  Quote: ... PTGS2 (1:100, Proteintech, 12375-1-AP), 4-HNE (1:100 ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... TOM70 (14528-1-AP, Proteintech, 1/10000), TIMM22 (14927-1-AP ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... MIA40 (21090-1-AP, Proteintech, 1/2500), TIMM23 (11123-1-AP ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... TOM40 (18409-1-AP, Proteintech, 1/10000), TOM70 (14528-1-AP ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... HRI (20499-1-AP, Proteintech, 1/3000), GAPDH (5174S ...
• A cross-species proteomic map reveals neoteny of human synapse development

  Li Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... GDI1 (Proteintech, 10249-1-AP, 1:100), CFL1 (Cell Signaling Technology ...
• Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons

  Daniel M. Virga, et al., bioRxiv - Cell Biology 2023

  Quote: ... MFF (Proteintech #17090-1-AP, 1:1000); phospho-MFF (Affinity Bioscience #AF2365 ...
• Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin

  Stephanie L. Baringer, et al., bioRxiv - Neuroscience 2023

  Quote: ... TOM20 (ProteinTech, 66777-1-Ig, 1:1000), and beta-actin (Sigma ...
• Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin

  Stephanie L. Baringer, et al., bioRxiv - Neuroscience 2023

  Quote: ... APP (ProteinTech, 60342-1-Ig, 1:1000), IRP1 (Cell Signaling ...
• TRiPPing the sensors: The osmosensing pathway of Polycystin 2

  K.M. Márquez-Nogueras, et al., bioRxiv - Physiology 2023

  Quote: ... Arl13b (1:100, #17711-1-AP; ProteinTech) overnight at 4°C ...
• TRiPPing the sensors: The osmosensing pathway of Polycystin 2

  K.M. Márquez-Nogueras, et al., bioRxiv - Physiology 2023

  Quote: ... MAP4 (1:1000; #11229-1-AP; ProteinTech), p-MAP4 (1:1000 ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... CGA (Proteintech, 10529-1-AP, 1:3000), CREB (Cell Signalling Technology ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... ATF4 (Proteintech, 10835-1-AP, 1:5000), VAMP 2 (Synaptic Systems ...
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... β-actin (1:1000, 20536-1-AP, Proteintech), followed by incubation with secondary horseradish peroxidase-conjugated antibody (Santa Cruz Biotechnology ...
• The soluble guanylyl cyclase pathway is inhibited to evade androgen deprivation-induced senescence and enable progression to castration resistance

  Ling Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Bcl2 (1:2,000, Proteintech, 12789-1-AP), Survivin (1:1,000 ...
• Tunable DNMT1 degradation reveals cooperation of DNMT1 and DNMT3B in regulating DNA methylation dynamics and genome organization

  Andrea Scelfo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... LAMINB1 (1:1000, Proteintech 12987-1-AP).
• Early and late chaperone intervention therapy boosts XBP1s and ADAM10, restores proteostasis, and rescues learning in Alzheimer’s Disease mice

  Jennifer M. Hafycz, et al., bioRxiv - Neuroscience 2023

  Quote: ... ATF4 (1:500, ProteinTech, 60035-1-Ig); peIF2α (1:100 ...
• Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

  Aitor Martinez, et al., bioRxiv - Neuroscience 2023

  Quote: ... CISD2 (Proteintech, 13318-1-AP, 1:1000), FLAG (Cell Signaling ...
• Small Molecule Activators of B56-PP2A Restore 4E-BP Expression and Function to Suppress Cap-dependent Translation in Cancer Cells

  Michelle A. Lum, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ATF4 (Proteintech, 10835-1-AP, 1:2,000), TFE3 (CST-14779 ...
• mTORC1 Regulates the Metabolic Switch of Postnatal Cardiomyocytes During Regeneration

  Wyatt G. Paltzer, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and GAPDH (Proteintech, 60004-1, 1:1000). The antibody binding was then visualized using the Odyssey FC (LI-COR ...
• Characterization of m⁶A modifiers and RNA modifications in uterine fibroids

  Jitu W. George, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CBLL1 (1:1000; 21179-1-AP; Proteintech), FTO (1:1000 ...
• Characterization of m⁶A modifiers and RNA modifications in uterine fibroids

  Jitu W. George, et al., bioRxiv - Cancer Biology 2023

  Quote: ... WTAP (1:1000; 10200-1-AP; Proteintech), CBLL1 (1:1000 ...
• Characterization of m⁶A modifiers and RNA modifications in uterine fibroids

  Jitu W. George, et al., bioRxiv - Cancer Biology 2023

  Quote: ... FTO (1:1000; 27226-1-AP; Proteintech), ALKBH5 (11:1000 ...
• Characterization of m⁶A modifiers and RNA modifications in uterine fibroids

  Jitu W. George, et al., bioRxiv - Cancer Biology 2023

  Quote: ... METTL14 (1:1000; 26158-1-AP; Proteintech), RBM15 (1:1000 ...
• Sox9 accelerates vascular ageing by regulating extracellular matrix composition and stiffness

  Maria Faleeva, et al., bioRxiv - Molecular Biology 2023

  Quote: ... LH3 (Proteintech, 11027-1-AP, 1:250), Vinculin (Sigma Aldrich,V9264 ...
• Multi-omics map revealed PPARα activation protecting against myocardial ischemia-reperfusion injury by maintaining cardiac metabolic homeostasis

  Yun Gao, et al., bioRxiv - Cell Biology 2023

  Quote: ... PGC1α (Proteintech, 66369-1-Ig; 1:250). Alexa Fluor 488 AffiniPure Goat Anti-Rabbit IgG (H+L ...
• Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis

  Sandii Constable, et al., bioRxiv - Cell Biology 2023

  Quote: ... TALPID3 (1:500, Proteintech 24421-1-AP). Rabbit polyclonal antibodies against IFT140 (1:500) ...
• Traitor-virus-guided discovery of novel antiviral factors

  Caterina Prelli Bozzo, et al., bioRxiv - Microbiology 2023

  Quote: ... BST2 (Proteintech 13560-1-AP, 1:500), GBP5 (Santa Cruz #sc-1603539 ...