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601 - 650 of 5774 citations for 2 Chloro 1 1 trifluoromethyl 1 3 4 9 tetrahydro 2H beta carbolin 2 yl ethan 1 one since 2020

• Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway

  Iqbal Dulloo, et al., bioRxiv - Cell Biology 2022

  Quote: ... SEC11A (Proteintech, #14753-1-AP; 1:500), SEC11C (Novus Biologicals ...
• eIF2B localisation and its regulation during the integrated stress response is cell type specific

  Filipe M. Hanson, et al., bioRxiv - Cell Biology 2023

  Quote: ... PERK (1:1000, 20582-1-AP, Proteintech), GADD34 (1:500 ...
• eIF2B localisation and its regulation during the integrated stress response is cell type specific

  Filipe M. Hanson, et al., bioRxiv - Cell Biology 2023

  Quote: ... CHOP (1:1000, 15204-1-AP, Proteintech), ATF4 (1:750 ...
• eIF2B localisation and its regulation during the integrated stress response is cell type specific

  Filipe M. Hanson, et al., bioRxiv - Cell Biology 2023

  Quote: ... GADD34 (1:500, 10449-1-AP, Proteintech), CHOP (1:1000 ...
• Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy

  Elena Marchesan, et al., bioRxiv - Cell Biology 2023

  Quote: ... Mfn1 (1:600; Proteintech; 13798-1-AP) Parkin (1:1000 ...
• Cell division tracing combined with single-cell transcriptomics reveals new cell types and differentiation paths in the regenerating mouse lung

  Leila R. Martins, et al., bioRxiv - Cell Biology 2023

  Quote: ... Agr2 (1:100, #12275-1-AP, Proteintech), CC10 (1:500 ...
• Multi-omics analysis identifies RFX7 targets involved in tumor suppression and neuronal processes

  Katjana Schwab, et al., bioRxiv - Genomics 2022

  Quote: ... PIK3IP1 (1:500; #16826-1-AP, Proteintech).
• Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

  Mary E. Mohr, et al., bioRxiv - Cell Biology 2023

  Quote: ... PTGS2 (1:100, Proteintech, 12375-1-AP), 4-HNE (1:100 ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... TOM70 (14528-1-AP, Proteintech, 1/10000), TIMM22 (14927-1-AP ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... MIA40 (21090-1-AP, Proteintech, 1/2500), TIMM23 (11123-1-AP ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... TOM40 (18409-1-AP, Proteintech, 1/10000), TOM70 (14528-1-AP ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... HRI (20499-1-AP, Proteintech, 1/3000), GAPDH (5174S ...
• A cross-species proteomic map reveals neoteny of human synapse development

  Li Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... GDI1 (Proteintech, 10249-1-AP, 1:100), CFL1 (Cell Signaling Technology ...
• Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons

  Daniel M. Virga, et al., bioRxiv - Cell Biology 2023

  Quote: ... MFF (Proteintech #17090-1-AP, 1:1000); phospho-MFF (Affinity Bioscience #AF2365 ...
• Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin

  Stephanie L. Baringer, et al., bioRxiv - Neuroscience 2023

  Quote: ... TOM20 (ProteinTech, 66777-1-Ig, 1:1000), and beta-actin (Sigma ...
• Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin

  Stephanie L. Baringer, et al., bioRxiv - Neuroscience 2023

  Quote: ... APP (ProteinTech, 60342-1-Ig, 1:1000), IRP1 (Cell Signaling ...
• TRiPPing the sensors: The osmosensing pathway of Polycystin 2

  K.M. Márquez-Nogueras, et al., bioRxiv - Physiology 2023

  Quote: ... Arl13b (1:100, #17711-1-AP; ProteinTech) overnight at 4°C ...
• TRiPPing the sensors: The osmosensing pathway of Polycystin 2

  K.M. Márquez-Nogueras, et al., bioRxiv - Physiology 2023

  Quote: ... MAP4 (1:1000; #11229-1-AP; ProteinTech), p-MAP4 (1:1000 ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... CGA (Proteintech, 10529-1-AP, 1:3000), CREB (Cell Signalling Technology ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... ATF4 (Proteintech, 10835-1-AP, 1:5000), VAMP 2 (Synaptic Systems ...
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... β-actin (1:1000, 20536-1-AP, Proteintech), followed by incubation with secondary horseradish peroxidase-conjugated antibody (Santa Cruz Biotechnology ...
• The soluble guanylyl cyclase pathway is inhibited to evade androgen deprivation-induced senescence and enable progression to castration resistance

  Ling Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Bcl2 (1:2,000, Proteintech, 12789-1-AP), Survivin (1:1,000 ...
• Tunable DNMT1 degradation reveals cooperation of DNMT1 and DNMT3B in regulating DNA methylation dynamics and genome organization

  Andrea Scelfo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... LAMINB1 (1:1000, Proteintech 12987-1-AP).
• Early and late chaperone intervention therapy boosts XBP1s and ADAM10, restores proteostasis, and rescues learning in Alzheimer’s Disease mice

  Jennifer M. Hafycz, et al., bioRxiv - Neuroscience 2023

  Quote: ... ATF4 (1:500, ProteinTech, 60035-1-Ig); peIF2α (1:100 ...
• Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

  Aitor Martinez, et al., bioRxiv - Neuroscience 2023

  Quote: ... CISD2 (Proteintech, 13318-1-AP, 1:1000), FLAG (Cell Signaling ...
• Small Molecule Activators of B56-PP2A Restore 4E-BP Expression and Function to Suppress Cap-dependent Translation in Cancer Cells

  Michelle A. Lum, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ATF4 (Proteintech, 10835-1-AP, 1:2,000), TFE3 (CST-14779 ...
• mTORC1 Regulates the Metabolic Switch of Postnatal Cardiomyocytes During Regeneration

  Wyatt G. Paltzer, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and GAPDH (Proteintech, 60004-1, 1:1000). The antibody binding was then visualized using the Odyssey FC (LI-COR ...
• Characterization of m⁶A modifiers and RNA modifications in uterine fibroids

  Jitu W. George, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CBLL1 (1:1000; 21179-1-AP; Proteintech), FTO (1:1000 ...
• Characterization of m⁶A modifiers and RNA modifications in uterine fibroids

  Jitu W. George, et al., bioRxiv - Cancer Biology 2023

  Quote: ... WTAP (1:1000; 10200-1-AP; Proteintech), CBLL1 (1:1000 ...
• Characterization of m⁶A modifiers and RNA modifications in uterine fibroids

  Jitu W. George, et al., bioRxiv - Cancer Biology 2023

  Quote: ... FTO (1:1000; 27226-1-AP; Proteintech), ALKBH5 (11:1000 ...
• Characterization of m⁶A modifiers and RNA modifications in uterine fibroids

  Jitu W. George, et al., bioRxiv - Cancer Biology 2023

  Quote: ... METTL14 (1:1000; 26158-1-AP; Proteintech), RBM15 (1:1000 ...
• Sox9 accelerates vascular ageing by regulating extracellular matrix composition and stiffness

  Maria Faleeva, et al., bioRxiv - Molecular Biology 2023

  Quote: ... LH3 (Proteintech, 11027-1-AP, 1:250), Vinculin (Sigma Aldrich,V9264 ...
• Multi-omics map revealed PPARα activation protecting against myocardial ischemia-reperfusion injury by maintaining cardiac metabolic homeostasis

  Yun Gao, et al., bioRxiv - Cell Biology 2023

  Quote: ... PGC1α (Proteintech, 66369-1-Ig; 1:250). Alexa Fluor 488 AffiniPure Goat Anti-Rabbit IgG (H+L ...
• Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis

  Sandii Constable, et al., bioRxiv - Cell Biology 2023

  Quote: ... TALPID3 (1:500, Proteintech 24421-1-AP). Rabbit polyclonal antibodies against IFT140 (1:500) ...
• Traitor-virus-guided discovery of novel antiviral factors

  Caterina Prelli Bozzo, et al., bioRxiv - Microbiology 2023

  Quote: ... BST2 (Proteintech 13560-1-AP, 1:500), GBP5 (Santa Cruz #sc-1603539 ...
• The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes

  Amanda K. Riley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... USP9X 1:500 (Proteintech, 55054-1-AP), RIT1 1:1000 (Abcam ...
• H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs

  Brian Krug, et al., bioRxiv - Molecular Biology 2023

  Quote: ... PHC2 (Proteintech 12867-1-AP 1:1000). Membranes were washed three times in TBST ...
• Translation fidelity and respiration deficits in CLPP-deficient tissues: Mechanistic insights from mitochondrial complexome

  Jana Key, et al., bioRxiv - Molecular Biology 2023

  Quote: ... PLPBP (Proteintech, 25154-1-AP, 1:1000), HSPA9 (Oxford Biomedical Research ...
• Translation fidelity and respiration deficits in CLPP-deficient tissues: Mechanistic insights from mitochondrial complexome

  Jana Key, et al., bioRxiv - Molecular Biology 2023

  Quote: ... COX15 (Proteintech, 11441-1-AP, 1:1000), PTCD1 (Abclonal ...
• Translation fidelity and respiration deficits in CLPP-deficient tissues: Mechanistic insights from mitochondrial complexome

  Jana Key, et al., bioRxiv - Molecular Biology 2023

  Quote: ... ALDH18A1 (Proteintech, 17719-1-AP, 1:1000), HSP60 (SantaCruz sc-13115 ...
• Inhibition of KLK8 promotes pulmonary endothelial repair by restoring VE-cadherin/Akt/FOXM1 pathway

  Ying Zhao, et al., bioRxiv - Physiology 2023

  Quote: ... ZO-1 (Proteintech Cat# 21773-1-AP), intercellular adhesion molecule 1 (ICAM-1 ...
• Traitor-virus-guided discovery of novel antiviral factors

  Caterina Prelli Bozzo, et al., bioRxiv - Microbiology 2023

  Quote: ... CC2D1B (Proteintech #20774-1-AP, 1:500), HMOX1 (Sigma MA1-112 ...
• Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis

  Sandii Constable, et al., bioRxiv - Cell Biology 2023

  Quote: ... CEP97 (1:200, Proteintech #22050-1-AP), Cyclin D1 (1:500 ...
• ARHGAP32 as a novel RhoGAP interacting with desmoplakin is required for desmosomal organization and assembly

  Hua Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-DSG 1 (Proteintech, 24587-1-AP), anti-DSG1 (Santa Cruz ...
• Cytosolic RNA binding of the mitochondrial TCA cycle enzyme malate dehydrogenase (MDH2)

  Michelle Noble, et al., bioRxiv - Cell Biology 2023

  Quote: ... HuR (Proteintech 11910-1-AP, 1:1000).
• Cytosolic RNA binding of the mitochondrial TCA cycle enzyme malate dehydrogenase (MDH2)

  Michelle Noble, et al., bioRxiv - Cell Biology 2023

  Quote: ... Tom20 (Proteintech 11802-1-AP, 1:1000), Tom70 (Proteintech 14528-1-AP ...
• Cytosolic RNA binding of the mitochondrial TCA cycle enzyme malate dehydrogenase (MDH2)

  Michelle Noble, et al., bioRxiv - Cell Biology 2023

  Quote: ... Tom70 (Proteintech 14528-1-AP, 1:1000), Nucleolin (Abcam ab50279 ...
• Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis

  Sandii Constable, et al., bioRxiv - Cell Biology 2023

  Quote: ... CEP131 (1:500, Proteintech #25735-1-AP), CEP164 (1:500 ...
• Parkinson’s genes orchestrate pyroptosis through selective trafficking of mtDNA to leaky lysosomes

  Mai Nguyen, et al., bioRxiv - Cell Biology 2023

  Quote: ... TOMM40 (Proteintech, 18409-1-AP, 1:1000). Between primary antibodies ...
• Bioengineered human colon organoids with in vivo-like complexity and function

  Olga Mitrofanova, et al., bioRxiv - Bioengineering 2023

  Quote: ... SLC26A2 (1:100, Proteintech, 27759-1-AP), MUC5B (1:100 ...