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1 - 50 of 433 citations for N 3R Pyrrolidin 3 ylmethyl acetamide since 2020

• Longitudinal in vivo micro-CT-based approach allows spatio-temporal characterization of fracture healing patterns and assessment of biomaterials in mouse femur defect models

  Esther Wehrle, et al., bioRxiv - Bioengineering 2021

  Quote: ... n=8) or collagen scaffolds+BMP-2 (2.5μg/scaffold; PeproTech, London, UK; n=8). Perioperative analgesia (25 mg/L ...
• Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

  Katarina Stoklund Dittlau, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 1% insulin transferrin selenium (Cat N° 41400045) in IMDM (Cat N° 12440053) supplemented with 5 ng/ml recombinant human basic fibroblast growth factor (bFGF) (Peprotech, Cat N° 100-18B). Medium was changed every 4 days ...
• Fully synthetic hydrogels promote robust crypt formation in intestinal organoids

  Ella A Hushka, et al., bioRxiv - Bioengineering 2024

  Quote: ... Noggin (“N,” 100 ng/mL, PeproTech), R-spondin-conditioned medium (“R,” 5% v/v ...
• Hematopoietic lineages diverge within the stem cell compartment

  Mina N. F. Morcos, et al., bioRxiv - Systems Biology 2020

  Quote: ... Interleukin-3 (rmIL-3 20ng/ml, PeproTech), Erythropoietin (rhEPO ...
• ALX1-related Frontonasal Dysplasia Results From Defective Neural Crest Cell Development and Migration

  Jonathan Pini, et al., bioRxiv - Cell Biology 2020

  Quote: ... 20 ng/ml Interleukin-3 (IL-3, Peprotech) and 20 ng/ml IL-6 (Peprotech) ...
• Induction of Ventral Spinal V0 Interneurons from Mouse Embryonic Stem Cells

  Jennifer Pardieck, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and neurotrophin-3 (NT-3, recombinant human, PeproTech, 450-03 ...
• Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease

  Isabella Fraschilla, et al., bioRxiv - Immunology 2022

  Quote: ... 5ng/mL of interleukin 3 (IL-3, Peprotech) and macrophage colony stimulating factor (M-CSF ...
• The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies

  Roxanne Hsiang-Chi Liou, et al., bioRxiv - Cell Biology 2023

  Quote: ... neurotrophin-3 (NT-3, 10 μg/mL, PeproTech), basic fibroblast growth factor (bFGF ...
• Generation and benchmarking of a collection of hiPSC lines from Schizophrenia Patients with Diverse Clinical Profiles

  Elena Rita Vecchi, et al., bioRxiv - Neuroscience 2024

  Quote: ... 20 ng/mL Interleukin-3 (IL-3) (Peprotech). The medium was changed daily ...
• Novel lentiviral vectors for gene therapy of sickle cell disease combining gene addition and gene silencing strategies

  Mégane Brusson, et al., bioRxiv - Genetics 2022

  Quote: ... 20 ng/mL interleukin-3 (IL-3) (Peprotech) and 10 mM SR1 (StemCell) ...
• RNA methylation controls stress granule formation and function during erythropoiesis

  Rajesh Gunage, et al., bioRxiv - Cell Biology 2024

  Quote: ... Interleukin 3 (IL-3; PeproTech, Cat #200-03), and 3U/mL Erythropoietin (EPO ...
• eIF6 rebinding dynamically couples ribosome maturation and translation

  Pekka Jaako, et al., bioRxiv - Cell Biology 2021

  Quote: ... murine interleukin 3 (mIL-3; 10 ng/mL, PeproTech) and murine granulocyte-colony stimulating factor (mG-CSF ...
• Developing Human Pluripotent Stem Cell-Based Cerebral Organoids with a Controllable Microglia Ratio for Modeling Brain Development and Pathology

  Ranjie Xu, et al., bioRxiv - Neuroscience 2021

  Quote: ... and interleukin-3 (IL-3, 25 ng/ml, Peprotech) to promote myeloid differentiation ...
• A human stem cell-derived neurosensory-epithelial circuitry on-a-chip to model herpes simplex virus reactivation

  Pietro Giuseppe Mazzara, et al., bioRxiv - Microbiology 2020

  Quote: ... Neurotrophin-3 10ng/ml (NT-3 450-03; Peprotech) and Ascorbic Acid 200 μM (AA 49752 ...
• The most common human ADAR1p150 Zα domain mutation P193A is well tolerated in mice and does not activate the integrated stress response pathway

  Zhen Liang, et al., bioRxiv - Genetics 2022

  Quote: ... 10ng/mL recombinant mouse interleukin 3 (rmIL-3, Peprotech) and 10ng/mL recombinant human interleukin 6 (rhIL-6 ...
• SIRPα+ PD-L1+ bone marrow macrophages aid AML growth by modulating T cell function

  Flora Birch, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 6 ng/mL murine interleukin-3 (mIL-3) (Peprotech). Every two days ...
• Presenilin-dependent regulation of tau pathology via the autophagy/proteasome pathway

  Anna del Ser-Badia, et al., bioRxiv - Neuroscience 2023

  Quote: ... NT-3 (Peprotech) and cAMP (Sigma ...
• Thyroid hormone and thyromimetics inhibit myelin and axonal degeneration and oligodendrocyte loss in EAE

  P Chaudhary, et al., bioRxiv - Neuroscience 2020

  Quote: ... neurotrophin-3 (NT-3, 1 ng/ml, PeproTech, Rocky Hill, NJ), and ciliary neurotrophic factor (CNTF,10 ng/ml ...
• Hematopoietic stem cell gene therapy improves outcomes in a clinically relevant mouse model of Multiple Sulfatase Deficiency

  Vi Pham, et al., bioRxiv - Neuroscience 2024

  Quote: ... 6 ng/mL interleukin-3 (IL-3) (PeproTech, Rocky Hill, NJ) and 2 uL Lentiblast Premium Transduction Enhancer (OZBiosciences ...
• Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques

  Byung-Chul Lee, et al., bioRxiv - Cell Biology 2023

  Quote: ... and rhesus interleukin 3 (IL-3)(10 ng/ml) (all Peprotech) for 2 to 3 weeks at 37°C in a humidified atmosphere with 5% CO2 ...
• CFC-seq: identification of full-length capped RNAs unveil enhancer-derived transcription

  Chi Wai Yip, et al., bioRxiv - Genomics 2024

  Quote: ... 10 ng/ml neurotrophin-3 (NT-3, PeproTech; Cat.No. 450-03), and 0.5 μg/ml laminin) ...
• Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells

  Rachel Wellington, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and 10 ng/mL interleukin-3 (hIL-3, Peprotech #200-03) and again put on a shaker at 37°C ...
• Effect of the daily exposure of 1.7 GHz LTE electromagnetic field in early fetal brain development using a human brain organoid model of the cerebral cortex

  Gyu Yeon Park, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and recombinant human neurotrophin-3 (NT-3; Peprotech, USA #450-03). The organoids were cultured in fresh medium every other day until day 42 to induce differentiation of neural progenitor cells ...
• Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

  Katarina Stoklund Dittlau, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 10 ng/ml GDNF (Peprotech, Cat N° 450-10B) was additionally added to the day four medium ...
• SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination

  Tal Iram, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 1 ng/ml neurotrophin-3 (NT-3; Peprotech, Cat#450-03) at 37°C with 10% CO2 ...
• CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes

  Mable Lam, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 1 ng/ml neurotrophin-3 (NT-3; Peprotech, Cat#450-03) at 37°C with 10% CO2 ...
• pHusion: A robust and versatile toolset for automated detection and analysis of exocytosis

  Ellen C. O’Shaughnessy, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 1 ng/ml neurotrophin-3 (NT-3; Peprotech, Cat#450-03) at 37°C with 10% CO2 ...
• Directed Evolution of Adenine Base Editors with Increased Activity and Therapeutic Application

  Nicole M. Gaudelli, et al., bioRxiv - Genomics 2020

  Quote: ... and Flt-3 (Peprotech). Following 48 h and 144 h post culturing ...
• Modeling Down syndrome neurodevelopment with isogenic cerebral organoids

  Jan T. Czerminski, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and NT-3 (Peprotech) for 18 days ...
• Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins

  Takeshi Uemura, et al., bioRxiv - Neuroscience 2020

  Quote: ... human NT-3 (Peprotech), human FGF acidic/FGF-1 (Peprotech) ...
• Directed Evolution of Adenine Base Editors with Increased Activity and Therapeutic Application

  Nicole M. Gaudelli, et al., bioRxiv - Genomics 2020

  Quote: ... and Flt-3 (Peprotech) and cultured for 48 hours prior to electroporation.
• Scalable, optically-responsive human neuromuscular junction model reveals convergent mechanisms of synaptic dysfunction in familial ALS

  Daniel Chen, et al., bioRxiv - Neuroscience 2024

  Quote: ... CHIR99021 (Peprotech; 3 uM), and Y-27632 (Peprotech ...
• Mitochondrial Dysfunction in Alzheimer’s Disease Is Driven By Excess ER-Calcium Release in Patient-Derived Neurons

  Sarah Mustaly-Kalimi, et al., bioRxiv - Neuroscience 2024

  Quote: ... and neurotrophin 3 (PeproTech). Induced neurons were fed with 50:50 mixture of astrocyte-conditioned medium (provided by Dr ...
• Cell fate determination is associated with changes in competing transcriptional units in the human GATA1 and GATA2 lineage-determining transcription factors

  Erik M Anderson, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and IL-3 (Peprotech).
• Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes

  Lucas H. Armitage, et al., bioRxiv - Immunology 2021

  Quote: ... 25 ng/mL recombinant human IL-3 (rhIL-3, PeproTech, Rocky Hill, NJ), and 100 ng/mL recombinant human M-CSF (rhM-CSF ...
• Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies

  Sigurbjörn Markusson, et al., bioRxiv - Biochemistry 2024

  Quote: ... and 1 ng/ml recombinant human neutrophin 3 (NT-3; Peprotech 450-03) and allowed to recover and proliferate at +37 °C/10% CO2 ...
• Evolutionary fingerprints of EMT in pancreatic cancers

  Luigi Perelli, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 20 ng/mL human recombinant FGF (Peprotech, cat. n. 100-18B), 1X ITS liquid media supplement (Sigma-Millipore ...
• The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus

  Vikrant K. Bhosle, et al., bioRxiv - Cell Biology 2022

  Quote: ... Recombinant human N-SLIT2 was purchased from PeproTech (Cranbury, NJ, USA). Endotoxin levels in all preparations were measured using ToxinSensor™ Chromogenic LAL Endotoxin Assay Kit (GenScript ...
• Mutational screens highlight glycosylation as a modulator of CSF3R activity

  Michael J. Hollander, et al., bioRxiv - Biochemistry 2022

  Quote: ... and 5 ng/mL recombinant murine interleukin-3 (IL-3, PeproTech 213-13-10ug). Expi293F cells (Thermo Fisher Scientific A14527 ...
• Low-density lipoprotein receptor-related protein 1 (LRP1) is a negative regulator of oligodendrocyte progenitor cell differentiation in the adult mouse brain

  Loic Auderset, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1ng/ml neurotrophin-3 (Peprotech), 1 ng/ml biotin (Sigma) ...
• Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

  Marian Hruska-Plochan, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

  Marian Hruska-Plochan, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• PU.1 expression defines distinct functional activities in the phenotypic HSC compartment in a mouse model of inflammatory stress

  James S. Chavez, et al., bioRxiv - Cell Biology 2021

  Quote: ... 10ng/mL IL-3 (Peprotech), 10ng/mL GM-CSF (Peprotech) ...
• TRACE-Seq Reveals Clonal Reconstitution Dynamics of Gene Targeted Human Hematopoietic Stem Cells

  Rajiv Sharma, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1ng/mL IL-3 (PeproTech), 3U/mL erythropoietin (eBiosciences) ...
• LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

  Marc Emmenegger, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system

  Yunbing Shen, et al., bioRxiv - Immunology 2021

  Quote: ... IL-3 (PeproTech, #213-13), and IL-6 (PeproTech ...
• Efficient transgenesis and homology-directed gene targeting in monolayers of primary human small intestinal and colonic epithelial stem cells

  Keith A. Breau, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 3 μM SB202190 (Peprotech 1523072), 50 ng/mL mEGF (Peprotech 315-09) ...
• The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells

  Valerio E.C. Piscopo, et al., bioRxiv - Cell Biology 2023

  Quote: ... NT-3 (10ng/mL, Peprotech), HGF (5ng/mL ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... + 10ng/ml IL-3 (PeproTech) + 20ng/ml IL-6 (PeproTech)) ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... IL-3 (20ng/mL; Peprotech), and IL-6 (20ng/mL ...