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251 - 300 of 1773 citations for tert Butyl 2 chloro 5H pyrrolo 3 4 b pyridine 6 7H carboxylate since 2020

• Circular RNA AEBP2: A novel regulator in dendritic cell development

  Qinfeng Zhou, et al., bioRxiv - Immunology 2024

  Quote: ... 10 ng/ml interleukin 4 (IL-4) (PeproTech, Rocky Hill, NJ) and10 ng/ml granulocyte/macrophage colony stimulating factor (GM-CSF ...
• Machine learning engineered PoLixNano nanoparticles overcome delivery barriers for nebulized mRNA therapeutics

  Dandan Zhang, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... and 10 ng/mL Interleukin 4 (IL-4) (214-14, PEPROTECH). The medium was half-replaced every 2 days ...
• Low-density lipoprotein receptor-related protein 1 (LRP1) is a negative regulator of oligodendrocyte progenitor cell differentiation in the adult mouse brain

  Loic Auderset, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1ng/ml neurotrophin-3 (Peprotech), 1 ng/ml biotin (Sigma) ...
• Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

  Marian Hruska-Plochan, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

  Marian Hruska-Plochan, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• PU.1 expression defines distinct functional activities in the phenotypic HSC compartment in a mouse model of inflammatory stress

  James S. Chavez, et al., bioRxiv - Cell Biology 2021

  Quote: ... 10ng/mL IL-3 (Peprotech), 10ng/mL GM-CSF (Peprotech) ...
• TRACE-Seq Reveals Clonal Reconstitution Dynamics of Gene Targeted Human Hematopoietic Stem Cells

  Rajiv Sharma, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1ng/mL IL-3 (PeproTech), 3U/mL erythropoietin (eBiosciences) ...
• LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

  Marc Emmenegger, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system

  Yunbing Shen, et al., bioRxiv - Immunology 2021

  Quote: ... IL-3 (PeproTech, #213-13), and IL-6 (PeproTech ...
• Efficient transgenesis and homology-directed gene targeting in monolayers of primary human small intestinal and colonic epithelial stem cells

  Keith A. Breau, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 3 μM SB202190 (Peprotech 1523072), 50 ng/mL mEGF (Peprotech 315-09) ...
• The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells

  Valerio E.C. Piscopo, et al., bioRxiv - Cell Biology 2023

  Quote: ... NT-3 (10ng/mL, Peprotech), HGF (5ng/mL ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... + 10ng/ml IL-3 (PeproTech) + 20ng/ml IL-6 (PeproTech)) ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... IL-3 (20ng/mL; Peprotech), and IL-6 (20ng/mL ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... FLT-3 (100ng/mL; Peprotech), IL-3 (20ng/mL ...
• A dialysis medium refreshment cell culture set-up for an osteoblast-osteoclast coculture

  M.A.M. Vis, B.W.M. de Wildt, K. Ito, S. Hofmann, bioRxiv - Bioengineering 2022

  Quote: ... 50 ng/mL receptor activator of NFκ-B ligand (RANKL, 310-01, PeproTech) was added to the coculture medium and maintained for the rest of the culture ...
• A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma

  Jonathan H. Sussman, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 2.5 ng/mL human epidermal growth factor (PeproTech, cat. AF-100-15-B), 2.5 ng/mL human basic fibroblast growth factor (PeproTech ...
• Development of serum substitute medium for bone tissue engineering

  Sana Ansari, Keita Ito, Sandra Hofmann, bioRxiv - Bioengineering 2022

  Quote: ... Basic fibroblast growth factor (b-FGF, 100-18B) was purchased from Peprotech (UK). Recombinant human bone morphogenetic protein-2 (rhBMP-2 ...
• Matrix vesicle isolation from a three-dimensional in vitro bone model

  Sana Ansari, et al., bioRxiv - Bioengineering 2023

  Quote: ... Basic fibroblast growth factor (b-FGF, 100-18B) was purchased from Peprotech (UK). Recombinant human bone morphogenetic protein-2 (rhBMP-2 ...
• The selective autophagy receptor p62 and the heat shock protein HSP27 facilitate lysophagy via the formation of phase-separated condensates

  Elizabeth R. Gallagher, Erika L.F. Holzbaur, bioRxiv - Cell Biology 2022

  Quote: ... i3Neurons were cryo-preserved in i3Neuron media (BrainPhys Neuronal Medium supplemented [StemCell] with 2% B27 [Gibco], 10ng/mL BDNF [PreproTech], 10ng/mL NT-3 [PeproTech], and 1µg/mL Laminin [Corning]) with 10% DMSO added ...
• STK25 is an IRF5 kinase that promotes TLR7/8-mediated inflammation

  Matthew R. Rice, et al., bioRxiv - Biochemistry 2023

  Quote: ... The expression of IL-6 in culture supernatants was detected using the Murine IL-6 Mini ABTS ELISA Development Kit (PeproTech, 900-M50) according to the manufacturer’s protocol.
• Presynapses are mitophagy pit stops that prevent axon degeneration

  Wai Kit Lam, et al., bioRxiv - Cell Biology 2024

  Quote: ... 10 ng/ml Neurotrophin-3 (NT-3) (reconstituted in 0.1% BSA/DPBS) (PeproTech; 450-03), 0.5X B-27 supplement (Thermo Fisher Scientific ...
• Phospho-proteomics reveals that RSK signaling is required for proliferation of natural killer cells stimulated with IL-2 or IL-15

  Melanie A. MacMullan, et al., bioRxiv - Immunology 2021

  Quote: ... Interleukin-2 (IL-2) (PeproTech 200-02) was added at a concentration of 100 U/mL during each media refresh ...
• Phospho-proteomic analysis of CAR-T cell signaling following activation by antigen-presenting cancer cells

  Melanie A. MacMullan, et al., bioRxiv - Immunology 2022

  Quote: ... Interleukin-2 (IL-2) (PeproTech, 200-02) was added at a concentration of 100 U/mL during each media refresh ...
• In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer

  Dzana Dervovic, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and human interleukin-2 (hIL-2, PeproTech) at 30 U/ml ...
• Central role of Prominin-1 in lipid rafts during liver regeneration

  Myeong-Suk Bahn, et al., bioRxiv - Cell Biology 2022

  Quote: ... cells were treated with human recombinant interleukin-6 (Peprotech).
• IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α

  Erik Van Dis, et al., bioRxiv - Immunology 2021

  Quote: ... 20 ng/mL IL-6 from PeproTech (216-16), 2.5 μg/mL rat anti-mouse IFN-γ from Biolegend (505801 ...
• Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation

  Xuyong Chen, et al., bioRxiv - Immunology 2021

  Quote: ... were stimulated with mIL-6 (50 ng/mL, PeproTech), hTGF-β1 (2 ng/mL) ...
• SDF-1/CXCR4 inhibition prevents paradoxical generation of cisplatin-induced pro-metastatic niches

  Giulia Bertolini, et al., bioRxiv - Cancer Biology 2020

  Quote: ... IL-6 10ng/ml (200-06) (all from Peprotech); neutralizing Ab anti-human/mouse SDF-1 25μg/ml (MAB310 ...
• Modeling Genetic Epileptic Encephalopathies using Brain Organoids

  Daniel J. Steinberg, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 10ng/ml Human IL-6 (Peprotech; 200-06). After 24hr ...
• Inhibition of granuloma triglyceride synthesis imparts control of Mycobacterium tuberculosis through curtailed inflammatory responses

  Stanzin Dawa, et al., bioRxiv - Immunology 2021

  Quote: ... BMDMs were pretreated with IL-6 (200-06, Peprotech) at 10ng/mL for overnight and infection protocol was followed as above ...
• Interferon-regulated genetic programs and JAK/STAT pathway activate the intronic promoter of the short ACE2 isoform in renal proximal tubules

  Jakub Jankowski, et al., bioRxiv - Genomics 2021

  Quote: ... IL-6 and IL-1β (all obtained from Peprotech) for 12 hours in concentration of 10 ng/ml ...
• Heart-on-a-chip model of immune-induced cardiac dysfunction reveals the role of free mitochondrial DNA and therapeutic effects of endothelial exosomes

  Rick Xing Ze Lu, et al., bioRxiv - Bioengineering 2023

  Quote: ... IL-6 and/or IL-8 (purchased from Peprotech) were added at concentration of 10ng/ml ...
• Unravelling the glycome in human intervertebral disc degeneration: Aberrant glycosylation modulates inflammation and metabolism

  Kieran Joyce, et al., bioRxiv - Bioengineering 2024

  Quote: ... IL-6 and TNF-α were purchased from Peprotech. Primocin was purchased from InvivoGen ...
• Heat shock protein 90 is a master regulator of HIV-1 latency

  Somaya Noorsaeed, et al., bioRxiv - Microbiology 2024

  Quote: ... IL-6 and IL-15 were obtained from Peprotech. The concentrations used are shown in Table S2 for each compound.
• The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia

  Kentson Lam, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 20ng/ml hIL-6 (all cytokines from Peprotech) for 1-2 days prior to use for downstream assays.
• Organoid Polymer Functionality and Mode of Klebsiella Pneumoniae Membrane Antigen Presentation Regulates Ex Vivo Germinal Center Epigenetics in Young and Aged B Cells

  Pamela L. Graney, et al., bioRxiv - Immunology 2020

  Quote: ... 1% P/S and 10 ng/mL interleukin-4 (IL-4, Peprotech) was added to each organoid ...
• In-depth immunometabolic profiling by measuring cellular protein translation inhibition via bioorthogonal noncanonical amino acid tagging (CENCAT)

  Frank Vrieling, et al., bioRxiv - Immunology 2024

  Quote: ... Interferon γ (IFNγ) and interleukin-4 (IL-4) were acquired from Peprotech. ODN2006 was purchased from HyCult ...
• “A negative feedback loop mediated by the NR4A family of nuclear hormone receptors restrains expansion of B cells that receive signal one in the absence of signal two”

  Corey Tan, et al., bioRxiv - Immunology 2020

  Quote: ... Murine IL-4 (Peprotech), anti-CD40 (hm40-3 clone ...
• Identification, crystallization and epitope determination of public TCR shared and expanded in COVID-19 patients

  Xiuyuan Lu, et al., bioRxiv - Immunology 2021

  Quote: ... and IL-4 (Peprotech) for 6 days.
• Genome-wide screens identify calcium signaling as a key regulator of IgE⁺ plasma cell differentiation and survival

  Rebecca Newman, Pavel Tolar, bioRxiv - Immunology 2021

  Quote: ... 100nm IL-4 (Peprotech) was added into the culture media ...
• L-type calcium channels link oxidative stress to calcium signaling pathway and membrane excitability: Insights from computational modeling of dopaminergic neurons

  M.A. Andres, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 20ng/mL recombinant human fibroblast growth factor-basic (FGF-b; PeproTech US, NJ). hNPCs were maintained under 37°C and 5% CO2 conditions ...
• Targeting of MMP-13 prevents aortic aneurysm formation in Marfan mice

  Laura-Marie A. Zimmermann, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-BMP-7 GF (#500-P198 B, Peprotech, Cranbury, NJ, USA, WB: 1:2000), anti-collagen I (#ab34710 ...
• Tracking coreceptor switch of the transmitted/founder HIV-1 identifies co-evolution of HIV-1 antigenicity, coreceptor usage and CD4 subset targeting

  Manukumar Honnayakanahalli Marichannegowda, et al., bioRxiv - Microbiology 2023

  Quote: ... interleukin 2 (IL-2) (50 U/ml; PeproTech), soluble anti-CD3 (0.5 μg/ml ...
• ApTOLL, a new therapeutic aptamer for cytoprotection and (re)myelination after Multiple Sclerosis

  Beatriz Fernández-Gómez, et al., bioRxiv - Neuroscience 2023

  Quote: ... and FGF-2 (Fibroblast Growth Factor-2: Peprotech). Finally ...
• Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI

  Sergio Castañeda-Zegarra, et al., bioRxiv - Immunology 2020

  Quote: ... and interleukin 4 (IL-4; 20 ng/mL; PeproTech, Stockholm, Sweden; #214-14) were used to induce CSR to IgG1 ...
• Radiation-induced rescue effect on human breast carcinoma cells is regulated by macrophages

  Spoorthy Pathikonda, et al., bioRxiv - Cancer Biology 2023

  Quote: ... M0 cells were treated with 40 ng/ml Interleukin 4 (IL-4, PeproTech) (Tedesco et al ...
• Sulfonated rhodamines as impermeable labelling substrates for cell surface protein visualization

  Ramona Birke, et al., bioRxiv - Biochemistry 2021

  Quote: ... 10 ng/mL NT‐3 (PeproTech) and 1 μg/mL Laminin (Gibco)) ...
• Human induced pluripotent stem cell-derived vessels as dynamic atherosclerosis model on a chip

  A. Mallone, et al., bioRxiv - Bioengineering 2021

  Quote: ... 25 ng/mL IL-3 (PeproTech), 2 mM Glutamax ...
• Direct neuronal reprogramming by temporal identity factors

  Camille Boudreau-Pinsonneault, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 10ng/ml NT-3 (PeproTech). At D14 ...
• Generation of SIV resistant T cells and Macrophages from Nonhuman Primate Induced Pluripotent Stem Cells with Edited CCR5 locus

  Saritha S. D’Souza, et al., bioRxiv - Cell Biology 2021

  Quote: ... 20ng/ml of IL-3 (Peprotech) and 20ng/ml of IL-6 (Peprotech ...