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201 - 250 of 795 citations for 5 Methylsulfamoylmethyl 1H indole 3 carboxylic acid methyl ester since 2020

• C9orf72 repeat expansion-carrying iPSC-microglia from FTD patients show increased phagocytic activity concomitantly with decreased number of autophagosomal-lysosomal vesicles

  Hannah Rostalski, et al., bioRxiv - Neuroscience 2024

  Quote: ... 10 ng/ml IL-3 (200-03, Peprotech), and under 18% O2 ...
• Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer’s disease

  Hyo Lee, et al., bioRxiv - Neuroscience 2024

  Quote: 3 cytokines: 100 ng/mL IL-34 (Peprotech), 50 ng/mL TGF-β1 (Millitenyi Biotech) ...
• Single-chain nanobody inhibition of Notch and avidity enhancement utilizing the β-pore forming toxin Aerolysin

  Andrew C.D. Lemmex, et al., bioRxiv - Biochemistry 2024

  Quote: ... 10ng/ml Human IL-3 (Peprotech, 200-03), and 10ng/ml Human Flt3-Ligand (Peprotech ...
• Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids

  Kaja Nicole Wächtershäuser, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 250 ng/ml recombinant R-spondin-3 (PeproTech), 500 ng/ml hydrocortisone (Sigma) ...
• Graphene-polymer Nanofibers Enable Optically Induced Electrical Maturation in Stem Cell-Derived Cardiomyocytes and Brain Organoids

  Erin LaMontagne, et al., bioRxiv - Bioengineering 2024

  Quote: ... + 10 ng/mL NT-3 (PeproTech, 450-03) + 200 μM L-ascorbic acid (Sigma-Aldrich ...
• Behavioral-transcriptomic landscape of engineered T cells targeting human cancer organoids

  Johanna F. Dekkers, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 5 ng/ml EGF (Peprotech), 20 ng/ml FGF-10 (Peprotech) ...
• A non-invasive method to generate induced pluripotent stem cells from primate urine

  Johanna Geuder, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5 ng/mL bFGF (PeproTech), 5 ng/mL PDGF-AB (PeproTech ...
• Blocking antibodies against integrin-α3, -αM, and -αMβ2 de-differentiate myofibroblasts and reverse lung and kidney fibroses

  Michael JV White, et al., bioRxiv - Immunology 2022

  Quote: ... 5 ng/ml TGFβ (Peprotech) was added to induce myofibroblast formation [74] ...
• Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity

  Elien Grajchen, et al., bioRxiv - Immunology 2022

  Quote: ... rhTGFβ (5 ng/ml, Peprotech), soluble anti-CD3ε (1.25 µg/ml ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... 5 ng/mL TPO (PeproTech), 50 ng/mL SCF (PeproTech) ...
• Microglia orchestrate neuronal activity in brain organoids

  Ilkka Fagerlund, et al., bioRxiv - Neuroscience 2020

  Quote: ... 5 ng/mL BMP4 (PeproTech), 25 ng/mL Activin A (PeproTech) ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... 5 ng/mL Flt3L (PeproTech), 5 ng/mL TPO (PeproTech) ...
• Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity

  Mina Shahriyari, et al., bioRxiv - Cell Biology 2021

  Quote: ... medium with 5 μ(Peprotech) and 10% knockout serum replacement (ThermoFisher Scientific ...
• The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies

  Roxanne Hsiang-Chi Liou, et al., bioRxiv - Cell Biology 2023

  Quote: ... insulin (5 μg/mL, PeproTech) and forskolin (10 μM ...
• iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease

  Oriol Busquets, et al., bioRxiv - Neuroscience 2024

  Quote: ... + 5 ng/ml TPO (PeProtech) + 50 ng/ul M-CSF (PeProtech ...
• Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion

  Matthew J. White, et al., bioRxiv - Cell Biology 2023

  Quote: ... 5 ng/ml EGF (PeproTech), 0.5 μg/ml hydrocortisone (Sigma) ...
• Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids

  Rebecca Sebastian, et al., bioRxiv - Neuroscience 2023

  Quote: ... and dorsomorphin (5 mM, Peprotech) for dual SMAD inhibition ...
• The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2

  Rahul K. Suryawanshi, et al., bioRxiv - Immunology 2024

  Quote: ... 5 nM heregulin-β1 (Peprotech), and 100 μg/ml Primocin (InvivoGen ...
• Mass Generation and Long-term Expansion of Hepatobiliary Organoids from Adult Primary Human Hepatocytes

  Ary Marsee, et al., bioRxiv - Cell Biology 2024

  Quote: ... 5 ng/mL HGF (Peprotech), 2 nM glucagon (ProSpec) ...
• Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions

  Yan Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... 5 ng/mL FGF (Peprotech), 4 ng/mL PDGF-AA (Peprotech) ...
• Mass Generation and Long-term Expansion of Hepatobiliary Organoids from Adult Primary Human Hepatocytes

  Ary Marsee, et al., bioRxiv - Cell Biology 2024

  Quote: ... 5 ng/mL HGF (Peprotech), 250 ng/mL RPSO3 (Peprotech) ...
• Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome

  Michael P. East, et al., bioRxiv - Biochemistry 2024

  Quote: ... 5 ng/ml hEGF (PEPROTECH), 37.5 ng/ul hHeregulin-beta (PEPROTECH ...
• Zebrafish Avatar-test predicts patient’s tumor response to chemotherapy in breast cancer: a co-clinical study towards personalized medicine

  Raquel V. Mendes, et al., bioRxiv - Cancer Biology 2024

  Quote: ... FGF7 (5 ng·mL-1, Peprotech), FGF10 (20 ng·mL-1 ...
• Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis

  Jun Wu, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5 ng/mL bFGF and 5 ng/mL TGF-β (Peprotech, 96-100-21-10). Cells were passaged upon reaching approximately 80% confluence in IMRCs Medium ...
• Expression of terminal deoxynucleotidyl transferase (TdT) identifies lymphoid-primed progenitors in human bone marrow

  YeEun Kim, et al., bioRxiv - Immunology 2022

  Quote: ... 5□ng/ml FLT3L and 5□ng/ml IL-7 (all from Peprotech, London, UK) in OP9 media (SF7 media) ...
• Molecular Changes in Prader-Willi Syndrome Neurons Reveals Clues About Increased Autism Susceptibility

  A. Kaitlyn Victor, et al., bioRxiv - Neuroscience 2021

  Quote: ... 30 ng/mL NT-3 (Peprotech, Rocky Hill, NJ), and 1% insulin-transferrin-sodium selenite premix (ITS ...
• Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells

  M. Kyle Cromer, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1ng/mL IL-3 (PeproTech, Rocky Hill, NJ, USA), 3U/mL erythropoietin (eBiosciences ...
• Human Deep Cortical Neurons Promote Regeneration and Recovery After Cervical Spinal Cord Injury

  Vanessa M. Doulames, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rho-associated protein kinase inhibitor (3 uM; 1293823; PeproTech) was added to the media for 1 day post replating.
• Lithium inhibits tryptophan catabolism via the inflammation-induced kynurenine pathway in human microglia

  Ria Göttert, et al., bioRxiv - Neuroscience 2020

  Quote: ... and IL-3 (10 ng/ml; all from Peprotech). Day 10 cells were harvested and FACsorted based on CD43 expression ...
• Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles

  Denise Ragusa, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 20 ng/ml IL-3 (Peprotech, London, UK). Cell lines were tested for Mycoplasma contamination using MycoSensor PCR Assay Kit (Agilent ...
• NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies

  Stephan Steinke, et al., bioRxiv - Neuroscience 2022

  Quote: ... 10 ng/ml NT-3 (10 ng/ml, PeproTech), mouse laminin (0.2 μg/ml ...
• A CRISPRi/a platform in iPSC-derived microglia uncovers regulators of disease states

  Nina M. Dräger, et al., bioRxiv - Neuroscience 2022

  Quote: ... 10ng/mL NT-3 (PeproTech; Cat. No. 450-03), 10ng/mL BDNF ...
• MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity

  Ya-Lin Lu, et al., bioRxiv - Neuroscience 2020

  Quote: ... 10 ng/mL human NT-3 (Peprotech, 450-03), 1 μM retinoic acid (RA ...
• NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies

  Stephan Steinke, et al., bioRxiv - Neuroscience 2022

  Quote: ... 10 ng/ml NT-3 (10 ng/ml, PeproTech), mouse laminin (0.2 μg/ml ...
• Identification of Drugs Blocking SARS-CoV-2 Infection using Human Pluripotent Stem Cell-derived Colonic Organoids

  Xiaohua Duan, et al., bioRxiv - Microbiology 2020

  Quote: ... 3 μM CHIR99021 and 100 ng/ml hEGF (Peprotech) in Advance DMEM F12 medium supplemented with 1X B27 supplement (Gibco) ...
• p38γMAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions

  LN Marziali, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 ng/ml Neurotrophin 3 (NT3) (PeproTech; 450-03), and 20 ng/ml PDGF-AA (PeproTech ...
• ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons

  Jacob A. Klickstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... and NT-3 (450-03) were obtained from PeproTech. LLOME (16008 ...
• Heterotypic interaction promotes asymmetric division of human hematopoietic stem and progenitor cells

  Adrian Candelas, et al., bioRxiv - Cell Biology 2023

  Quote: ... 20ng/mL human IL-3 (Peprotech ref.300-23) and 10ng/mL human G-CSF (Prepotech ref.200-02 ...
• Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single cell resolution

  Nicolò Caporale, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 20 ng/mL neurotrophin-3 (Peprotech, #450-03) to promote differentiation of neural progenitors ...
• CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signalling

  Sean P. Giblin, et al., bioRxiv - Immunology 2023

  Quote: ... supplemented with 1 ng/ml mouse IL-3 (Peprotech). Stable hCXCR1 expressing Ba/F3 cells were generated by transfection in a 0.4cm-electroporation cuvette with 50ul 10 mg/ml tRNA ...
• A Two-Step Activation Mechanism Enables Mast Cells to Differentiate their Response between Extracellular and Invasive Enterobacterial Infection

  Christopher von Beek, et al., bioRxiv - Immunology 2023

  Quote: ... and 10ng/ml recombinant IL-3 (Peprotech, #213-13). Medium was changed every 3-4 days to a fresh flask in the first 4 weeks of culture ...
• CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development

  Xiangling Meng, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 20 ng/ml NT-3 (Peprotech, 450-03). From day 44 ...
• Myelin plasticity in ventral tegmental area is required for opioid reward

  Belgin Yalçın, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 1 ng/ml NT-3 (PeproTech, 450-03) was used ...
• Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing

  Svenja K. Tetzlaff, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and NT-3 (10 ng/ml, Peprotech #450-03) supplemented with Doxycycline (2 μg/ml ...
• A long-acting prolactin to combat lactation insufficiency

  Kasia Kready, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... and 10ng/mL mouse IL-3 (PeproTech; 213-13), unless specified otherwise ...
• iPSC-derived models of PACS1 syndrome reveal transcriptional and functional deficits in neuron activity

  Lauren Rylaarsdam, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 20 ng/mL Neurotrophin 3 (PeproTech, 450-03). Organoids were transitioned to neurobasal-A medium supplemented with 1x B-27 beginning at day 43 until the desired endpoint.
• Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies

  Sumaiya Nazeen, et al., bioRxiv - Genomics 2024

  Quote: ... 10ng/mL NT-3 (PeproTech; Cat. No. 450-03), 10ng/mL BDNF (PeproTech ...
• LRRK2 kinase dependent and independent function on endolysosomal repair promotes macrophage cell death

  Rebecca Morrison, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 25 ng/ml IL-3 (200-03, Peprotech). 20 ml fresh factory media was added once per week and after 4-5 weeks macrophage precursors were collected from the supernatant ...
• Liprin-α/RIM complex regulates the dynamic assembly of presynaptic active zones via liquid-liquid phase separation

  Gaowei Jin, et al., bioRxiv - Neuroscience 2024

  Quote: ... and NT-3 (10 ng/ml, Peprotech #450-03) supplemented with Doxycycline (2 μg/ml ...
• In vivo genome editing of human hematopoietic stem cells for treatment of blood disorders by mRNA delivery

  Saijuan Xu, et al., bioRxiv - Bioengineering 2024

  Quote: ... 6 ng mL-1 mIL-3 (PeproTech, 213-13), and 10 ng mL-1 mIL-6 (PeproTech ...