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201 - 250 of 2342 citations for 2R 5S 5 4 amino 5 fluoro 2 oxopyrimidin 1 2H yl 1 3 oxathiolan 2 yl methyl butyrate WXC04778 since 2020

• A non-invasive method to generate induced pluripotent stem cells from primate urine

  Johanna Geuder, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5 ng/mL bFGF (PeproTech), 5 ng/mL PDGF-AB (PeproTech ...
• Blocking antibodies against integrin-α3, -αM, and -αMβ2 de-differentiate myofibroblasts and reverse lung and kidney fibroses

  Michael JV White, et al., bioRxiv - Immunology 2022

  Quote: ... 5 ng/ml TGFβ (Peprotech) was added to induce myofibroblast formation [74] ...
• Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity

  Elien Grajchen, et al., bioRxiv - Immunology 2022

  Quote: ... rhTGFβ (5 ng/ml, Peprotech), soluble anti-CD3ε (1.25 µg/ml ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... 5 ng/mL TPO (PeproTech), 50 ng/mL SCF (PeproTech) ...
• Microglia orchestrate neuronal activity in brain organoids

  Ilkka Fagerlund, et al., bioRxiv - Neuroscience 2020

  Quote: ... 5 ng/mL BMP4 (PeproTech), 25 ng/mL Activin A (PeproTech) ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... 5 ng/mL Flt3L (PeproTech), 5 ng/mL TPO (PeproTech) ...
• Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity

  Mina Shahriyari, et al., bioRxiv - Cell Biology 2021

  Quote: ... medium with 5 μ(Peprotech) and 10% knockout serum replacement (ThermoFisher Scientific ...
• The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies

  Roxanne Hsiang-Chi Liou, et al., bioRxiv - Cell Biology 2023

  Quote: ... insulin (5 μg/mL, PeproTech) and forskolin (10 μM ...
• iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease

  Oriol Busquets, et al., bioRxiv - Neuroscience 2024

  Quote: ... + 5 ng/ml TPO (PeProtech) + 50 ng/ul M-CSF (PeProtech ...
• Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion

  Matthew J. White, et al., bioRxiv - Cell Biology 2023

  Quote: ... 5 ng/ml EGF (PeproTech), 0.5 μg/ml hydrocortisone (Sigma) ...
• Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids

  Rebecca Sebastian, et al., bioRxiv - Neuroscience 2023

  Quote: ... and dorsomorphin (5 mM, Peprotech) for dual SMAD inhibition ...
• The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2

  Rahul K. Suryawanshi, et al., bioRxiv - Immunology 2024

  Quote: ... 5 nM heregulin-β1 (Peprotech), and 100 μg/ml Primocin (InvivoGen ...
• Mass Generation and Long-term Expansion of Hepatobiliary Organoids from Adult Primary Human Hepatocytes

  Ary Marsee, et al., bioRxiv - Cell Biology 2024

  Quote: ... 5 ng/mL HGF (Peprotech), 2 nM glucagon (ProSpec) ...
• Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions

  Yan Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... 5 ng/mL FGF (Peprotech), 4 ng/mL PDGF-AA (Peprotech) ...
• Mass Generation and Long-term Expansion of Hepatobiliary Organoids from Adult Primary Human Hepatocytes

  Ary Marsee, et al., bioRxiv - Cell Biology 2024

  Quote: ... 5 ng/mL HGF (Peprotech), 250 ng/mL RPSO3 (Peprotech) ...
• Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome

  Michael P. East, et al., bioRxiv - Biochemistry 2024

  Quote: ... 5 ng/ml hEGF (PEPROTECH), 37.5 ng/ul hHeregulin-beta (PEPROTECH ...
• Calcium-dependent protein acyltransferase DHHC21 controls activation of CD4⁺ T cells

  Bieerkehazhi Shayahati, et al., bioRxiv - Immunology 2020

  Quote: ... Th2 (anti-IFN-γ-Bioexcel,10μg/ml, IL-4-Peprotech, 10ng/ml, hIL-2–50U/ml), and Th17 (anti-IFN-γ-10μg/ml ...
• Calcium-dependent protein acyltransferase DHHC21 controls activation of CD4⁺ T cells

  Bieerkehazhi Shayahati, et al., bioRxiv - Immunology 2020

  Quote: ... Th1 (anti-IL-4 - Bioexcel,10μg/ml, IL-12 - Peprotech,10ng/ml, hIL-2–50U/ml), Th2 (anti-IFN-γ-Bioexcel,10μg/ml ...
• Correction of age-associated defects in dendritic cell functions enables CD4⁺ T cells to eradicate tumors in the elderly

  Dania Zhivaki, et al., bioRxiv - Immunology 2022

  Quote: ... coated with anti-CD3 (4 μg/ml) and anti-CD28 (4 μg/ml) in the presence of IL-2 (Peprotech, 50ng/ml). CD19+ B cells were stimulated for 24 hours using Purified F(ab’)2 Goat anti-mouse IgM Antibody (BioLegend) ...
• Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation

  Tim Vangansewinkel, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 10 ng/ml human fibroblast growth factor-2 (FGF-2, Peprotech) to synchronize the cells to the early OPC stage ...
• α-Synuclein acts as a cholesteryl-ester sensor on lipid droplets regulating organelle size and abundance

  Reeba Susan Jacob, et al., bioRxiv - Cell Biology 2024

  Quote: ... 8 ng/mL fibroblast growth factor-2 (FGF-2, Peprotech #100-18B). Cells were passaged with collagenase IV (Worthington #LS004180) ...
• A conserved role of hnRNPL in regulating alternative splicing of transcriptional regulators necessary for B cell activation

  Poorani Ganesh Subramani, et al., bioRxiv - Immunology 2023

  Quote: ... supplemented with 1 ng/mL IL-4 (PeproTech). On subsequent days ...
• Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis

  Jun Wu, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5 ng/mL bFGF and 5 ng/mL TGF-β (Peprotech, 96-100-21-10). Cells were passaged upon reaching approximately 80% confluence in IMRCs Medium ...
• Expression of terminal deoxynucleotidyl transferase (TdT) identifies lymphoid-primed progenitors in human bone marrow

  YeEun Kim, et al., bioRxiv - Immunology 2022

  Quote: ... 5□ng/ml FLT3L and 5□ng/ml IL-7 (all from Peprotech, London, UK) in OP9 media (SF7 media) ...
• p38γMAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions

  LN Marziali, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 ng/ml Neurotrophin 3 (NT3) (PeproTech; 450-03), and 20 ng/ml PDGF-AA (PeproTech ...
• CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signalling

  Sean P. Giblin, et al., bioRxiv - Immunology 2023

  Quote: ... supplemented with 1 ng/ml mouse IL-3 (Peprotech). Stable hCXCR1 expressing Ba/F3 cells were generated by transfection in a 0.4cm-electroporation cuvette with 50ul 10 mg/ml tRNA ...
• Myelin plasticity in ventral tegmental area is required for opioid reward

  Belgin Yalçın, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 1 ng/ml NT-3 (PeproTech, 450-03) was used ...
• In vivo genome editing of human hematopoietic stem cells for treatment of blood disorders by mRNA delivery

  Saijuan Xu, et al., bioRxiv - Bioengineering 2024

  Quote: ... 6 ng mL-1 mIL-3 (PeproTech, 213-13), and 10 ng mL-1 mIL-6 (PeproTech ...
• Secretome analysis of oligodendrocytes and precursors reveals their roles as contributors to the extracellular matrix and potential regulators of inflammation

  Marlesa I. Godoy, et al., bioRxiv - Neuroscience 2024

  Quote: ... and NT-3 (1 ng/ml, Peprotech, 450-03) for two days as previously described [11] ...
• Frequent Aneuploidy in Primary Human T Cells Following CRISPR-Cas9 cleavage

  A.D. Nahmad, et al., bioRxiv - Bioengineering 2021

  Quote: ... 50IU rhIL-2 (Peprotech) and P/S ...
• Brain capillary obstruction as a novel mechanism of anti-CD19 CAR T cell neurotoxicity

  Lila D Faulhaber, et al., bioRxiv - Neuroscience 2021

  Quote: ... murine IL-2 (Peprotech) (days 1-3 ...
• Long-read sequencing and profiling of RNA-binding proteins reveals the pathogenic mechanism of aberrant splicing of an SCN1A poison exon in epilepsy

  Hannah C Happ, et al., bioRxiv - Genetics 2023

  Quote: ... XAV939 (2 uM, PeproTech), LDN-193189 (100 nM ...
• Commensal bacteria promote type I interferon signaling to maintain immune tolerance

  Adriana Vasquez Ayala, et al., bioRxiv - Immunology 2022

  Quote: ... mouse IL-2 (Peprotech), and human TGF-beta (Peprotech) ...
• deCLUTTER²⁺ pipeline to analyze calcium traces in a novel stem cell model for ventral midbrain patterned astrocytes

  Martyna M. Grochowska, et al., bioRxiv - Neuroscience 2022

  Quote: ... and FGF-2 (Peprotech). The medium was refreshed every other day ...
• The CIpP activator, TR-57, is highly effective as a single agent and in combination with venetoclax against CLL cells in vitro

  Narjis Fatima, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 200 U/ml interleukin 2 (IL-2; Peprotech, Rocky Hill, NJ, USA) for 4 days ...
• Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson’s disease model with Lewy-like pathology

  Christina Paschou, et al., bioRxiv - Neuroscience 2024

  Quote: ... 20 ng/ml fibroblast growth factor-2 (FGF-2; Peprotech, Cranbury, NJ, USA), and 20 ng/ml epidermal growth factor (EGF ...
• A non-invasive method to generate induced pluripotent stem cells from primate urine

  Johanna Geuder, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5 ng/mL PDGF-AB (PeproTech) and 5 ng/mL EGF (Miltenyi Biotec) ...
• The Goldilocks Principle conferred by LDH isoenzymes controls murine T cell glycolysis and differentiation

  Xuyong Chen, Lingling Liu, Ruoning Wang, bioRxiv - Immunology 2022

  Quote: ... mIL-12 (5 ng/mL, PeproTech) (TH1 differentiation) ...
• Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function

  Valentina Stolz, et al., bioRxiv - Immunology 2022

  Quote: ... + 5 ng/mL TGF-b (PeproTech), stimulated with anti-CD3/anti-CD28 coated dynabeads (beads ...
• Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics

  Alba Rodriguez-Meira, et al., bioRxiv - Cancer Biology 2022

  Quote: ... GM-CSF (5 ng/mL, Peprotech), IL-3 (10 ng/mL ...
• Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation

  Xuyong Chen, et al., bioRxiv - Immunology 2021

  Quote: ... mIL-12 (5 ng/mL, PeproTech) for TH1 differentiation ...
• CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary cells

  Mitchell G. Kluesner, et al., bioRxiv - Bioengineering 2020

  Quote: ... IL-7 (5 ng/mL, PeproTech), and IL-15 (5 ng/mL ...
• T-cell Abca1 and Abcg1 cholesterol efflux pathways suppress T-cell apoptosis and senescence and increase atherosclerosis in middle-aged Ldlr^-/- mice

  Venetia Bazioti, et al., bioRxiv - Immunology 2022

  Quote: ... and 5 ng/mL TGFβ1 (Peprotech) in RPMI 1640 medium supplemented with 10% FCS ...
• Genome-wide screening in human kidney organoids identifies novel aspects of nephrogenesis

  Rosemarie Ungricht, et al., bioRxiv - Cell Biology 2021

  Quote: ... + 5 ng/ml human Noggin (Peprotech) with a medium change after 2 days ...
• Modeling Human Spine-Spinal Cord Organogenesis by hPSC-Derived Neuromesodermal Progenitors

  Dairui Li, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 5 ng/ml TGFβ1 (Peprotech) for 48 hours (day 0-day 2) ...
• Distinct eosinophil subsets are modulated by agonists of the commensal-metabolite and vitamin B3 receptor GPR109A during allergic-type inflammation

  Rossana Azzoni, et al., bioRxiv - Immunology 2022

  Quote: ... GM-CSF and IL-5 (Peprotech) in the presence or absence of niacin for 24 hours ...
• Differential chondrogenic differentiation between iPSC-derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

  Nazir M. Khan, et al., bioRxiv - Cell Biology 2022

  Quote: ... and 5 ng/ml rhbFGF (Peprotech). After 2-3 passage onto non-coated plates ...
• Scalable, optically-responsive human neuromuscular junction model reveals convergent mechanisms of synaptic dysfunction in familial ALS

  Daniel Chen, et al., bioRxiv - Neuroscience 2024

  Quote: ... and Y-27632 (Peprotech; 5 uM). On day 7 ...
• Phage DNA polymerase prevents deleterious on-target DNA damage and enhances precise CRISPR/Cas9 editing

  Qiaoyan Yang, et al., bioRxiv - Bioengineering 2023

  Quote: ... 5 ng/mL IL-15 (PeproTech), and 200 U/mL IL-2 (PeproTech) ...
• Phage DNA polymerase prevents deleterious on-target DNA damage and enhances precise CRISPR/Cas9 editing

  Qiaoyan Yang, et al., bioRxiv - Bioengineering 2023

  Quote: ... 5 ng/mL IL-7 (PeproTech), 5 ng/mL IL-15 (PeproTech) ...