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101 - 150 of 602 citations for 3 22 Dihydroxyolean 12 En 29 Oic Acid since 2020

• Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins

  Takeshi Uemura, et al., bioRxiv - Neuroscience 2020

  Quote: ... human NT-3 (Peprotech), human FGF acidic/FGF-1 (Peprotech) ...
• Directed Evolution of Adenine Base Editors with Increased Activity and Therapeutic Application

  Nicole M. Gaudelli, et al., bioRxiv - Genomics 2020

  Quote: ... and Flt-3 (Peprotech) and cultured for 48 hours prior to electroporation.
• Scalable, optically-responsive human neuromuscular junction model reveals convergent mechanisms of synaptic dysfunction in familial ALS

  Daniel Chen, et al., bioRxiv - Neuroscience 2024

  Quote: ... CHIR99021 (Peprotech; 3 uM), and Y-27632 (Peprotech ...
• Mitochondrial Dysfunction in Alzheimer’s Disease Is Driven By Excess ER-Calcium Release in Patient-Derived Neurons

  Sarah Mustaly-Kalimi, et al., bioRxiv - Neuroscience 2024

  Quote: ... and neurotrophin 3 (PeproTech). Induced neurons were fed with 50:50 mixture of astrocyte-conditioned medium (provided by Dr ...
• Cell fate determination is associated with changes in competing transcriptional units in the human GATA1 and GATA2 lineage-determining transcription factors

  Erik M Anderson, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and IL-3 (Peprotech).
• Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay

  Annika Zink, et al., bioRxiv - Cell Biology 2020

  Quote: ... ascorbic acid and 100 ng/ml FGF2 (PeproTech) and the same was used every day until day 13 ...
• Metabolic regulation of species-specific developmental rates

  Margarete Diaz-Cuadros, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and 12 ng/ml bFGF (PeproTech cat. no. 450-33). The medium was refreshed after 24 hours.
• Hypersensitivity of MAIT cells to Leukocidin ED indicates a Staphylococcus aureus immune evasion mechanism targeting the innate effector cell response

  Caroline Boulouis, et al., bioRxiv - Immunology 2021

  Quote: ... PBMC were incubated for 20 h with IL-12 (Peprotech) and IL-18 (MBL ...
• Tertiary lymphoid structures induced by CXCL13-producing CD4⁺ T cells increase tumor infiltrating CD8⁺ T cells and B cells in ovarian cancer

  Masayo Ukita, et al., bioRxiv - Immunology 2021

  Quote: ... or 10 ng/ml IL-12 (PeproTech, Montreal, Quebec, Canada) was added.
• Dendritic cell Piezo1 integrating mechanical stiffness and inflammatory signals directs the differentiation of T_H1 and T_reg cells in cancer

  Yuexin Wang, et al., bioRxiv - Immunology 2022

  Quote: ... cultures were supplemented with IL-12 (10 μg/ml, Peprotech) and anti-TGFβ1 mAb (20 μg/ml ...
• Peripheral Natural Killer cells from chronic hepatitis B patients display molecular hallmarks of T cell exhaustion

  M. Marotel, et al., bioRxiv - Immunology 2020

  Quote: Human PBMCs were stimulated with recombinant human IL-12 (Peprotech) and IL-18 (R&D Systems ...
• Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

  Or-Yam Revach, et al., bioRxiv - Cancer Biology 2024

  Quote: ... with 20 ng/mL murine IL-2 (Peprotech, 212-12). Cells were treated with anti-CD38 (Novus ...
• Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treat low-burden metastases

  Shih-Wen Huang, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 ng/ml IL-12 (Peprotech, Cranbury, NJ, USA). The expanded murine NK cells (CD19-TCRβ-NK1.1+CD11c+B220+ ...
• An IL-12 mRNA-LNP adjuvant enhances mRNA vaccine induced CD8⁺ T cell responses

  Emily A. Aunins, et al., bioRxiv - Immunology 2024

  Quote: ... Standards were prepared by diluting recombinant IL12p70 (Peprotech, 210-12) in assay media at a max concentration of 20,000 pg/mL with 2-fold serial dilutions ...
• Multi-Omic Atlas reveals cytotoxic phenotype and ROS-linked metabolic quiescence as key features of CTL-resistant HIV-infected CD4⁺ T-cells

  Alberto Herrera, et al., bioRxiv - Immunology 2024

  Quote: ... human anti-IL-12 (2µg/106 cells Peprotech 500-P154G), and Tumor Growth Factor (TGF)-β1 (10ng/106 Peprotech 100-21 ...
• Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes

  Lucas H. Armitage, et al., bioRxiv - Immunology 2021

  Quote: ... 25 ng/mL recombinant human IL-3 (rhIL-3, PeproTech, Rocky Hill, NJ), and 100 ng/mL recombinant human M-CSF (rhM-CSF ...
• Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies

  Sigurbjörn Markusson, et al., bioRxiv - Biochemistry 2024

  Quote: ... and 1 ng/ml recombinant human neutrophin 3 (NT-3; Peprotech 450-03) and allowed to recover and proliferate at +37 °C/10% CO2 ...
• Mutational screens highlight glycosylation as a modulator of CSF3R activity

  Michael J. Hollander, et al., bioRxiv - Biochemistry 2022

  Quote: ... and 5 ng/mL recombinant murine interleukin-3 (IL-3, PeproTech 213-13-10ug). Expi293F cells (Thermo Fisher Scientific A14527 ...
• Low-density lipoprotein receptor-related protein 1 (LRP1) is a negative regulator of oligodendrocyte progenitor cell differentiation in the adult mouse brain

  Loic Auderset, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1ng/ml neurotrophin-3 (Peprotech), 1 ng/ml biotin (Sigma) ...
• Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

  Marian Hruska-Plochan, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

  Marian Hruska-Plochan, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• PU.1 expression defines distinct functional activities in the phenotypic HSC compartment in a mouse model of inflammatory stress

  James S. Chavez, et al., bioRxiv - Cell Biology 2021

  Quote: ... 10ng/mL IL-3 (Peprotech), 10ng/mL GM-CSF (Peprotech) ...
• TRACE-Seq Reveals Clonal Reconstitution Dynamics of Gene Targeted Human Hematopoietic Stem Cells

  Rajiv Sharma, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1ng/mL IL-3 (PeproTech), 3U/mL erythropoietin (eBiosciences) ...
• LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

  Marc Emmenegger, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 (PeproTech #450-03) and IGF-1 (Stem Cell #78022 ...
• A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system

  Yunbing Shen, et al., bioRxiv - Immunology 2021

  Quote: ... IL-3 (PeproTech, #213-13), and IL-6 (PeproTech ...
• Efficient transgenesis and homology-directed gene targeting in monolayers of primary human small intestinal and colonic epithelial stem cells

  Keith A. Breau, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 3 μM SB202190 (Peprotech 1523072), 50 ng/mL mEGF (Peprotech 315-09) ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... + 10ng/ml IL-3 (PeproTech) + 20ng/ml IL-6 (PeproTech)) ...
• The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells

  Valerio E.C. Piscopo, et al., bioRxiv - Cell Biology 2023

  Quote: ... NT-3 (10ng/mL, Peprotech), HGF (5ng/mL ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... IL-3 (20ng/mL; Peprotech), and IL-6 (20ng/mL ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... FLT-3 (100ng/mL; Peprotech), IL-3 (20ng/mL ...
• HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport

  Hataf Khan, et al., bioRxiv - Microbiology 2020

  Quote: ... with 50 ng/ml phorbol 12-myristate 13-acetate (PMA, Peprotech) for 48 hours ...
• Non-canonical Hedgehog signaling through L-type voltage gated Ca²⁺ channels controls CD8⁺ T cell killing

  Joachim Hanna, et al., bioRxiv - Immunology 2021

  Quote: ... and 10ng/ml murine IL-2 (Peprotech, Cat no. 212-12). Human CD8+ T cells were cultured in ImmunoCult cell culture media (Stemcell Technologies ...
• cDC1 Coordinate Innate and Adaptive Responses in the Omentum required for T cell Priming and Memory

  David A. Christian, et al., bioRxiv - Immunology 2020

  Quote: ... or 200 ng of recombinant murine IL-12p70 (Peprotech: 210-12) immediately after immunization and once per day for the next two days after immunization ...
• Sex differences in NK cells mediated by the X-linked epigenetic regulator UTX

  Mandy I. Cheng, et al., bioRxiv - Immunology 2022

  Quote: ... with or without recombinant mouse IL-12 (20 ng/ml; Peprotech) and recombinant mouse IL-18 (10ng/ml ...
• A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice

  Naoki Kodama, et al., bioRxiv - Immunology 2022

  Quote: ... 10 ng/mL mIL-12 (PeproTech Inc., Rocky Hill, NJ, USA) and 10 μg/mL anti-IL-4 Ab (clone 11B11 ...
• “Target-and-release” nanoparticles for effective immunotherapy of metastatic ovarian cancer

  Ivan S. Pires, et al., bioRxiv - Bioengineering 2024

  Quote: ... IL-12 concentrations were measured via enzyme-linked immunoassay (ELISA) (Peprotech) and lipid content was quantified via the Stewart Assay.54
• Nuclear FAK aggravates CD8⁺ T cell exhaustion via the SP1-IL-6 axis in colorectal cancer

  Hao Kong, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 ng/mL IL-2 (#AF-212-12, PeproTech, US) for 24 h.
• Inhibition of UBE2N in regulatory T-cells boosts immunity against cancer

  Wanying Miao, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Murine recombinant IL-2 (100 U/mL; PeproTech, Cat# 212-12), murine recombinant TGF-β (5 ng/mL ...
• Presynapses are mitophagy pit stops that prevent axon degeneration

  Wai Kit Lam, et al., bioRxiv - Cell Biology 2024

  Quote: ... 10 ng/ml Neurotrophin-3 (NT-3) (reconstituted in 0.1% BSA/DPBS) (PeproTech; 450-03), 0.5X B-27 supplement (Thermo Fisher Scientific ...
• PVRL2 Suppresses Anti-tumor Immunity Through PVRIG- and TIGIT-Independent Pathways

  Jiuling Yang, et al., bioRxiv - Immunology 2024

  Quote: ... supplemented with 1,000 U/mL mouse IL-2 (PeproTech, cat. 212-12) for 7-9 days ...
• Substance P receptor signaling contributes to host maladaptive responses during enteric bacterial infection

  Michael Cremin, et al., bioRxiv - Immunology 2024

  Quote: ... 5 ng/mL murine IL-2 (Cat# 212-12 Peprotech Cranbury, NJ), and 10 ng/mL murine IL-12p40 (Cat# 210-12 Peprotech Cranbury ...
• Sulfonated rhodamines as impermeable labelling substrates for cell surface protein visualization

  Ramona Birke, et al., bioRxiv - Biochemistry 2021

  Quote: ... 10 ng/mL NT‐3 (PeproTech) and 1 μg/mL Laminin (Gibco)) ...
• Human induced pluripotent stem cell-derived vessels as dynamic atherosclerosis model on a chip

  A. Mallone, et al., bioRxiv - Bioengineering 2021

  Quote: ... 25 ng/mL IL-3 (PeproTech), 2 mM Glutamax ...
• Direct neuronal reprogramming by temporal identity factors

  Camille Boudreau-Pinsonneault, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 10ng/ml NT-3 (PeproTech). At D14 ...
• An in vivo CRISPR screening platform for prioritizing therapeutic targets in AML

  Shan Lin, et al., bioRxiv - Cancer Biology 2020

  Quote: ... IL-3 and IL-6 (PeproTech 300-07 ...
• Generation of SIV resistant T cells and Macrophages from Nonhuman Primate Induced Pluripotent Stem Cells with Edited CCR5 locus

  Saritha S. D’Souza, et al., bioRxiv - Cell Biology 2021

  Quote: ... 20ng/ml of IL-3 (Peprotech) and 20ng/ml of IL-6 (Peprotech ...
• A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition

  Yadira M. Soto-Feliciano, et al., bioRxiv - Cancer Biology 2022

  Quote: ... mouse IL-3 (10ng/µL, PeproTech), mouse SCF (20ng/µL ...
• AP-4 regulates neuronal lysosome composition, function, and transport via regulating export of critical lysosome receptor proteins at the trans-Golgi network

  Piyali Majumder, et al., bioRxiv - Cell Biology 2022

  Quote: ... 10 ng/mL NT-3 (PeproTech), and 1 μg/mL mouse Laminin (Thermo Fisher Scientific ...
• An overlapped natural antisense lncRNA FCER1A-AS controls anaphylactic reaction by promoting FcεRIα expression

  Ruo-yu Tang, Lan Yin, Liang Yao, Xiao-Ping Chen, bioRxiv - Immunology 2022

  Quote: ... 10 ng/ml IL-3 (Peprotech), and 10% fetal bovine serum(GIBCO ...
• A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukaemia

  José Luis Marín-Rubio, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 10 ng/mL interleukin-3 (PeproTech), and 20 ng/mL stem cell factor (PeproTech) ...