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1401 - 1450 of 2315 citations for 6 METHYL 4 4 NITRO PHENYL 2 OXO 1 2 3 4 TETRAHYDRO PYRIMIDINE 5 CARBOXYLIC ACID ETHYL ESTER since 2019

• Targeting RET Kinase in Neuroendocrine Prostate Cancer

  Halena VanDeusen, et al., bioRxiv - Cancer Biology 2019

  Quote: ... 5 ng/mL FGF2 (PeproTech), 10 ng/mL FGF10 (PeproTech) ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... 5 ng/mL TPO (PeproTech), 50 ng/mL SCF (PeproTech) ...
• Microglia orchestrate neuronal activity in brain organoids

  Ilkka Fagerlund, et al., bioRxiv - Neuroscience 2020

  Quote: ... 5 ng/mL BMP4 (PeproTech), 25 ng/mL Activin A (PeproTech) ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... 5 ng/mL Flt3L (PeproTech), 5 ng/mL TPO (PeproTech) ...
• Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity

  Mina Shahriyari, et al., bioRxiv - Cell Biology 2021

  Quote: ... medium with 5 μ(Peprotech) and 10% knockout serum replacement (ThermoFisher Scientific ...
• The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies

  Roxanne Hsiang-Chi Liou, et al., bioRxiv - Cell Biology 2023

  Quote: ... insulin (5 μg/mL, PeproTech) and forskolin (10 μM ...
• Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion

  Matthew J. White, et al., bioRxiv - Cell Biology 2023

  Quote: ... 5 ng/ml EGF (PeproTech), 0.5 μg/ml hydrocortisone (Sigma) ...
• Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids

  Rebecca Sebastian, et al., bioRxiv - Neuroscience 2023

  Quote: ... and dorsomorphin (5 mM, Peprotech) for dual SMAD inhibition ...
• iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease

  Oriol Busquets, et al., bioRxiv - Neuroscience 2024

  Quote: ... + 5 ng/ml TPO (PeProtech) + 50 ng/ul M-CSF (PeProtech ...
• Mass Generation and Long-term Expansion of Hepatobiliary Organoids from Adult Primary Human Hepatocytes

  Ary Marsee, et al., bioRxiv - Cell Biology 2024

  Quote: ... 5 ng/mL HGF (Peprotech), 250 ng/mL RPSO3 (Peprotech) ...
• Mass Generation and Long-term Expansion of Hepatobiliary Organoids from Adult Primary Human Hepatocytes

  Ary Marsee, et al., bioRxiv - Cell Biology 2024

  Quote: ... 5 ng/mL HGF (Peprotech), 2 nM glucagon (ProSpec) ...
• Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions

  Yan Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... 5 ng/mL FGF (Peprotech), 4 ng/mL PDGF-AA (Peprotech) ...
• Towards a biotechnological platform for the production of human pro-angiogenic growth factors in the green alga Chlamydomonas reinhardtii

  Montserrat Jarquín-Cordero, et al., bioRxiv - Plant Biology 2019

  Quote: ... cells were stimulated with either 50 ng·ml−1 recombinant hVEGF-165 for 5 min (Peprotech, Rocky Hill, NJ, USA), 20 ng·ml−1 recombinant hPDGF-B for 5 min (Peprotech ...
• Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis

  Jun Wu, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5 ng/mL bFGF and 5 ng/mL TGF-β (Peprotech, 96-100-21-10). Cells were passaged upon reaching approximately 80% confluence in IMRCs Medium ...
• Expression of terminal deoxynucleotidyl transferase (TdT) identifies lymphoid-primed progenitors in human bone marrow

  YeEun Kim, et al., bioRxiv - Immunology 2022

  Quote: ... 5□ng/ml FLT3L and 5□ng/ml IL-7 (all from Peprotech, London, UK) in OP9 media (SF7 media) ...
• Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson’s Disease

  Bo Am Seo, et al., bioRxiv - Neuroscience 2024

  Quote: ... 5 µg/ml of N-acetyl cysteine and 5 ng/ml HBEGF (#100-47, Peprotech) as previously described (Liddelow et al. ...
• Immunomodulatory effect of mycobacterial outer membrane vesicles coated nanoparticles

  Edna George, et al., bioRxiv - Bioengineering 2022

  Quote: ... hIL-8 and hIL-6 were estimated using their respective ELISA kits (Peprotech) according to the manufacturer’s instructions ...
• MAM-STAT3-induced upregulation of mitochondrial Ca⁺² causes immunosenescence in patients with type A mandibuloacral dysplasia

  Arshad Ahmed Padhiar, et al., bioRxiv - Cell Biology 2022

  Quote: Stat3 was activated in healthy iMSCs by adding the cytokine IL-6 (PeproTech, Rocky Hill ...
• Molecular Changes in Prader-Willi Syndrome Neurons Reveals Clues About Increased Autism Susceptibility

  A. Kaitlyn Victor, et al., bioRxiv - Neuroscience 2021

  Quote: ... 30 ng/mL NT-3 (Peprotech, Rocky Hill, NJ), and 1% insulin-transferrin-sodium selenite premix (ITS ...
• Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells

  M. Kyle Cromer, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1ng/mL IL-3 (PeproTech, Rocky Hill, NJ, USA), 3U/mL erythropoietin (eBiosciences ...
• Human Deep Cortical Neurons Promote Regeneration and Recovery After Cervical Spinal Cord Injury

  Vanessa M. Doulames, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rho-associated protein kinase inhibitor (3 uM; 1293823; PeproTech) was added to the media for 1 day post replating.
• Lithium inhibits tryptophan catabolism via the inflammation-induced kynurenine pathway in human microglia

  Ria Göttert, et al., bioRxiv - Neuroscience 2020

  Quote: ... and IL-3 (10 ng/ml; all from Peprotech). Day 10 cells were harvested and FACsorted based on CD43 expression ...
• Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles

  Denise Ragusa, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 20 ng/ml IL-3 (Peprotech, London, UK). Cell lines were tested for Mycoplasma contamination using MycoSensor PCR Assay Kit (Agilent ...
• NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies

  Stephan Steinke, et al., bioRxiv - Neuroscience 2022

  Quote: ... 10 ng/ml NT-3 (10 ng/ml, PeproTech), mouse laminin (0.2 μg/ml ...
• A CRISPRi/a platform in iPSC-derived microglia uncovers regulators of disease states

  Nina M. Dräger, et al., bioRxiv - Neuroscience 2022

  Quote: ... 10ng/mL NT-3 (PeproTech; Cat. No. 450-03), 10ng/mL BDNF ...
• MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity

  Ya-Lin Lu, et al., bioRxiv - Neuroscience 2020

  Quote: ... 10 ng/mL human NT-3 (Peprotech, 450-03), 1 μM retinoic acid (RA ...
• NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies

  Stephan Steinke, et al., bioRxiv - Neuroscience 2022

  Quote: ... 10 ng/ml NT-3 (10 ng/ml, PeproTech), mouse laminin (0.2 μg/ml ...
• Identification of Drugs Blocking SARS-CoV-2 Infection using Human Pluripotent Stem Cell-derived Colonic Organoids

  Xiaohua Duan, et al., bioRxiv - Microbiology 2020

  Quote: ... 3 μM CHIR99021 and 100 ng/ml hEGF (Peprotech) in Advance DMEM F12 medium supplemented with 1X B27 supplement (Gibco) ...
• CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development

  Xiangling Meng, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 20 ng/ml NT-3 (Peprotech, 450-03). From day 44 ...
• Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing

  Svenja K. Tetzlaff, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and NT-3 (10 ng/ml, Peprotech #450-03) supplemented with Doxycycline (2 μg/ml ...
• ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons

  Jacob A. Klickstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... and NT-3 (450-03) were obtained from PeproTech. LLOME (16008 ...
• Heterotypic interaction promotes asymmetric division of human hematopoietic stem and progenitor cells

  Adrian Candelas, et al., bioRxiv - Cell Biology 2023

  Quote: ... 20ng/mL human IL-3 (Peprotech ref.300-23) and 10ng/mL human G-CSF (Prepotech ref.200-02 ...
• Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single cell resolution

  Nicolò Caporale, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 20 ng/mL neurotrophin-3 (Peprotech, #450-03) to promote differentiation of neural progenitors ...
• A Two-Step Activation Mechanism Enables Mast Cells to Differentiate their Response between Extracellular and Invasive Enterobacterial Infection

  Christopher von Beek, et al., bioRxiv - Immunology 2023

  Quote: ... and 10ng/ml recombinant IL-3 (Peprotech, #213-13). Medium was changed every 3-4 days to a fresh flask in the first 4 weeks of culture ...
• A long-acting prolactin to combat lactation insufficiency

  Kasia Kready, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... and 10ng/mL mouse IL-3 (PeproTech; 213-13), unless specified otherwise ...
• iPSC-derived models of PACS1 syndrome reveal transcriptional and functional deficits in neuron activity

  Lauren Rylaarsdam, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 20 ng/mL Neurotrophin 3 (PeproTech, 450-03). Organoids were transitioned to neurobasal-A medium supplemented with 1x B-27 beginning at day 43 until the desired endpoint.
• Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies

  Sumaiya Nazeen, et al., bioRxiv - Genomics 2024

  Quote: ... 10ng/mL NT-3 (PeproTech; Cat. No. 450-03), 10ng/mL BDNF (PeproTech ...
• LRRK2 kinase dependent and independent function on endolysosomal repair promotes macrophage cell death

  Rebecca Morrison, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 25 ng/ml IL-3 (200-03, Peprotech). 20 ml fresh factory media was added once per week and after 4-5 weeks macrophage precursors were collected from the supernatant ...
• The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4

  Femke M. Feringa, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3 ng/ml Il-1α (AF-200-01A, Peprotech) and 400 ng/ml C1q (204876 ...
• Engineering inducible signaling receptors to enable erythropoietin-free erythropoiesis

  Aadit P. Shah, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... 1ng/mL interleukin-3 (PeproTech, Rocky Hill, NJ, USA), 3U/mL EPO (eBiosciences ...
• A non-invasive method to generate induced pluripotent stem cells from primate urine

  Johanna Geuder, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5 ng/mL PDGF-AB (PeproTech) and 5 ng/mL EGF (Miltenyi Biotec) ...
• The Goldilocks Principle conferred by LDH isoenzymes controls murine T cell glycolysis and differentiation

  Xuyong Chen, Lingling Liu, Ruoning Wang, bioRxiv - Immunology 2022

  Quote: ... mIL-12 (5 ng/mL, PeproTech) (TH1 differentiation) ...
• Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function

  Valentina Stolz, et al., bioRxiv - Immunology 2022

  Quote: ... + 5 ng/mL TGF-b (PeproTech), stimulated with anti-CD3/anti-CD28 coated dynabeads (beads ...
• Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics

  Alba Rodriguez-Meira, et al., bioRxiv - Cancer Biology 2022

  Quote: ... GM-CSF (5 ng/mL, Peprotech), IL-3 (10 ng/mL ...
• Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation

  Xuyong Chen, et al., bioRxiv - Immunology 2021

  Quote: ... mIL-12 (5 ng/mL, PeproTech) for TH1 differentiation ...
• CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary cells

  Mitchell G. Kluesner, et al., bioRxiv - Bioengineering 2020

  Quote: ... IL-7 (5 ng/mL, PeproTech), and IL-15 (5 ng/mL ...
• T-cell Abca1 and Abcg1 cholesterol efflux pathways suppress T-cell apoptosis and senescence and increase atherosclerosis in middle-aged Ldlr^-/- mice

  Venetia Bazioti, et al., bioRxiv - Immunology 2022

  Quote: ... and 5 ng/mL TGFβ1 (Peprotech) in RPMI 1640 medium supplemented with 10% FCS ...
• Genome-wide screening in human kidney organoids identifies novel aspects of nephrogenesis

  Rosemarie Ungricht, et al., bioRxiv - Cell Biology 2021

  Quote: ... + 5 ng/ml human Noggin (Peprotech) with a medium change after 2 days ...
• Proteogenomic analysis reveals RNA as an important source for tumor-agnostic neoantigen identification correlating with T-cell infiltration

  Celina Tretter, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 5 ng/mL IL-15 (Peprotech), 30 U/mL IL-2 (Peprotech ...
• Distinct eosinophil subsets are modulated by agonists of the commensal-metabolite and vitamin B3 receptor GPR109A during allergic-type inflammation

  Rossana Azzoni, et al., bioRxiv - Immunology 2022

  Quote: ... GM-CSF and IL-5 (Peprotech) in the presence or absence of niacin for 24 hours ...