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51 - 100 of 1365 citations for 1 3 Methoxyphenyl 6 7 dimethyl 6 azoniabicyclo 3.2.1 octane bromide since 2020

• Single-hit genome edition for expression of single-chain immunoglobulins by edited B cells

  Natsuko Ueda, et al., bioRxiv - Immunology 2022

  Quote: ... 20 ng/ml IL-6 (Peprotech) and 12 ng/ml IL-10 (R&D Systems).
• Histone H3K36me2-specific methyltransferase ASH1L is required for the MLL-AF9-induced leukemogenesis

  Mohammad B. Aljazi, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 10 ng/mL mIL-6 (PeproTech), and 10 ng/mL mIL-3 (PeproTech).
• Naked Mole-Rat Hematopoietic Stem and Progenitors are Highly Quiescent with an Inherent Myeloid Bias

  Stephan Emmrich, et al., bioRxiv - Cell Biology 2021

  Quote: ... 10ng/ml mIL-6 (all Peprotech). Naked mole-rat LTC (LIN−/Thy1.1int/CD34hi ...
• A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system

  Yunbing Shen, et al., bioRxiv - Immunology 2021

  Quote: ... and IL-6 (PeproTech, #216-16) for two days ...
• IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

  Holly Bachus, et al., bioRxiv - Immunology 2022

  Quote: ... +/- 100 ng of rIL-6 (PeproTech) daily for 3 days and challenged (i.n. ...
• Reprogramming human B cells with custom heavy chain antibodies

  Geoffrey L. Rogers, et al., bioRxiv - Immunology 2023

  Quote: ... 50 ng/mL IL-6 (Peprotech), 50 ng/mL IL-10 ...
• CRISPR/Cas9-based disease modelling and functional correction of Interleukin 7 Receptor alpha Severe Combined Immunodeficiency in T-lymphocytes and hematopoietic stem cells

  Rajeev Rai, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Interleukin-6 (50 ng/mL, Peprotech), StemReginin-1 (1 µM ...
• A Germline Point Mutation in the MYC-FBW7 Phosphodegron Initiates Hematopoietic Malignancies

  Brian Freie, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IL-6 (Peprotech, 10 ng/ml), IL-3 (Biovision ...
• Oncogenic RAS-Pathway Activation Drives Oncofetal Reprogramming and Creates Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia

  Mark Hartmann, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 50 ng/ml IL-6 (PeproTech), 50 ng/ml TPO (PeproTech) ...
• Succinate mediates inflammation-induced adrenocortical dysfunction

  Ivona Mateska, et al., bioRxiv - Immunology 2022

  Quote: ... IL-6 (20 ng/ml, PeproTech), TNFα(20 ng/ml ...
• Single-nucleus sequencing reveals enriched expression of genetic risk factors in Extratelencephalic Neurons sensitive to degeneration in ALS

  Francesco Limone, et al., bioRxiv - Neuroscience 2023

  Quote: ... IL-6 (Peprotech, 50 ng/ml), and IL-3 (Peprotech ...
• Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells

  Milad Rezvani, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 10 ng/ml IL-6 (Peprotech), and 10 ng/ml IL-11 (Peprotech) ...
• Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells

  Milad Rezvani, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 10 ng/ml IL-6 (Peprotech), and 10 ng/ml IL11 (Peprotech) ...
• A post-translational cysteine-to-serine conversion in human and mouse insulin generates a diabetogenic neoepitope

  Neetu Srivastava, et al., bioRxiv - Immunology 2024

  Quote: ... IL-6 (PeproTech, Cat # 216-16), and IL-12 (PeproTech ...
• Microbiome Modulation Uncouples Efficacy and Toxicity Induced by Programmed Death-1/Programmed Death-Ligand1 Blockade

  Laura Lucia Cogrossi, et al., bioRxiv - Immunology 2024

  Quote: ... IL-6 (10ng/mL; Peprotech, Inc.), anti-mouse IFNγ (10µg/mL ...
• Maintenance of haematopoietic stem cells by JAK inhibition and increased tyrosine-unphosphorylated STAT5

  Matthew J Williams, et al., bioRxiv - Cell Biology 2024

  Quote: ... IL-6 (10 ng/mL; PeproTech) and 0.1 mM β-mercaptoethanol (Gibco).
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... and IL-6 (20ng/mL; Peprotech)] for four days ...
• DNMT3A^R882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency

  Thomas Köhnke, et al., bioRxiv - Cancer Biology 2024

  Quote: ... GM-CSF and IL-6 (Peprotech) and editing was performed as described above ...
• Second generation of LNP based mRNA vaccine leads to a T cell–inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model

  Carole Fournier, et al., bioRxiv - Immunology 2024

  Quote: ... and IL-6 (PeproTech, #216-16) according to the supplemental Table 1 ...
• Generation of SIV resistant T cells and Macrophages from Nonhuman Primate Induced Pluripotent Stem Cells with Edited CCR5 locus

  Saritha S. D’Souza, et al., bioRxiv - Cell Biology 2021

  Quote: ... and 20ng/ml of IL-6 (Peprotech) was added to the co-culture ...
• miR-183/96/182 cluster is an important morphogenetic factor targeting PAX6 expression in differentiating human retinal organoids

  Lucie Peskova, et al., bioRxiv - Molecular Biology 2020

  Quote: ... On day 6 recombinant human BMP4 (Peprotech) was added to the culture to the final concentration 2.2 nM and then the medium was changed every 3rd day ...
• Mitochondrial respiration contributes to the interferon gamma response in antigen presenting cells

  Michael C. Kiritsy, et al., bioRxiv - Immunology 2020

  Quote: ... IL-6 (10ng/mL; Peprotech #216-16), IL-3 (10ng/mL ...
• ALX1-related Frontonasal Dysplasia Results From Defective Neural Crest Cell Development and Migration

  Jonathan Pini, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 20 ng/ml IL-6 (Peprotech), 1 million PBMC were processed using the CytoTune-iPS 2.0 Sendai Reprogramming Kit (Invitrogen ...
• Functional Screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair

  Juan A. Perez-Bermejo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... IL-6 (100 ng/mL) (all Peprotech) and UM171 (35 nM ...
• Physical activity regulates the immune response to breast cancer by a hematopoietic stem cell-autonomous mechanism

  Lyne Khair, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 2 ug/ml IL-6 (Peprotech). To quantify oxidative stress ...
• Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells

  Milad Rezvani, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and 6 ng/ml Activin A (Peprotech). On day 4 ...
• Single-chain nanobody inhibition of Notch and avidity enhancement utilizing the β-pore forming toxin Aerolysin

  Andrew C.D. Lemmex, et al., bioRxiv - Biochemistry 2024

  Quote: ... 50ng/ml IL-6 (Peprotech, 200-06), 10ng/ml Human IL-3 (Peprotech ...
• Generation of High-fidelity Blastocyst-like Structures from Porcine Expanded Pluripotent stem cell via Chemically inducing cell plasticity

  Zheng Liao, et al., bioRxiv - Cell Biology 2024

  Quote: ... 10.0 ng ml−1 IL-6 (Peprotech, cat. no. 200-06-100 ug), 10.0 ng ml−1 sIL-6R (Peprotech ...
• Obox4 promotes zygotic genome activation upon loss of Dux

  Youjia Guo, et al., bioRxiv - Molecular Biology 2024

  Quote: SP2/O-Ag14 myeloma and primary clones of hybridomas were cultured in GIT medium (catalog no. 63725715, Wako) supplemented with recombinant human interleukin-6 (IL-6) (catalog no. 20006, PeproTech). Cells were cultured in a humidified atmosphere containing 5% CO2 at 37°C and sub-cultured every day ...
• A disease-associated gene desert orchestrates macrophage inflammatory responses via ETS2

  CT Stankey, et al., bioRxiv - Immunology 2023

  Quote: ... The transfection mix was then added dropwise to 2.5×106 M0 macrophages (pre-cultured for 6 days in a 6-well plate in antibiotic-free RPMI1640 macrophage media containing M-CSF (50ng/ml, Peprotech) – with media change on d3) ...
• Pseudomonas aeruginosa-infected Myeloid-derived suppressor cells (MDSC) down-regulate lymphocyte activity and improves mice survival, following in vivo lung transfer

  Maëlys Born-Bony, et al., bioRxiv - Immunology 2024

  Quote: ... 100 μg/mL streptomycin) containing 30 ng/mL of mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) and Interleukin-6 (IL-6) (PeproTech). After 5 days ...
• Pseudomonas aeruginosa-infected Myeloid-derived suppressor cells (MDSC) down-regulate lymphocyte activity and improves mice survival, following in vivo lung transfer

  Maëlys Born-Bony, et al., bioRxiv - Immunology 2024

  Quote: ... 100 μg/mL streptomycin) containing 30 ng/mL of mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) and Interleukin-6 (IL-6) (PeproTech) and 4% CHO-SCF conditioned media ...
• Decoding the activated stem cell phenotype of the vividly maturing neonatal pituitary

  Emma Laporte, et al., bioRxiv - Developmental Biology 2022

  Quote: ... IL-6 (20 ng/ml; Peprotech, London, UK), IL-1β (10 ng/ml ...
• The Goldilocks Principle conferred by LDH isoenzymes controls murine T cell glycolysis and differentiation

  Xuyong Chen, Lingling Liu, Ruoning Wang, bioRxiv - Immunology 2022

  Quote: ... or with mIL-6 (50 ng/mL, PeproTech), hTGF-β1 (2 ng/mL) ...
• Evaluation of persistence and fate of ex vivo edited-HSC modified with donor template and Its role in correcting Sickle Cell Disease

  Sowmya Pattabhi, et al., bioRxiv - Genomics 2021

  Quote: ... hSCF and hIL-6 (Peprotech, Rocky Hill, NJ). The cells were cultured at low density (0.1 - 0.25×106 cells/ml ...
• PHF6 Interacts with LMO2 During Normal Haematopoiesis and in Leukaemia and Regulates Gene Expression and Genome Integrity

  Vesna S. Stanulović, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 10 ng/ml IL-6 (PeproTech 216-16). Cell populations were analysed using Flk1-APC ...
• SLAMF7 engagement super-activates macrophages in acute and chronic inflammation

  Daimon P. Simmons, et al., bioRxiv - Immunology 2020

  Quote: ... IL-6 and TNF-α were from Peprotech. ELISA kits for TNF-α ...
• Oxidized phospholipid oxPAPC induces a Th1-like phenotype in regulatory T cells and inhibits their protective function in atherosclerosis

  Brenna D. Appleton, et al., bioRxiv - Immunology 2023

  Quote: ... 25ng/ml IL-6 (Peprotech Cat # 216-16), 5ng/ml TGF-β ...
• Chromatin priming elements direct tissue-specific gene activity prior to hematopoietic specification

  Alexander Maytum, et al., bioRxiv - Genomics 2023

  Quote: ... 10⍰ng/ml IL-6 (PeproTech, 216-16)) and were left to incubate for 2.5 days at 37⍰°C ...
• IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells

  Sabrina Fischer, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mIL-6 (50 ng/ml) (216-16; PeproTech) and mSCF (50 ng/ml ...
• Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators

  Gracia Bonilla, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 5 ng/ml rmIL-6 (all from Peprotech). Progenitors were transferred to RetroNectin®-coated (Lonza ...
• FAS^lpr gene dosage tunes the extent of lymphoproliferation and T cell differentiation in lupus

  Ritu Bohat, et al., bioRxiv - Immunology 2023

  Quote: ... 30ng/ml of IL-6 (#216-16, PeproTech), 20ng/ml of IL-1p (#211-11B PeproTech) ...
• Germline Transmission of a Circular Human Artificial Chromosome in the Mouse

  Aleksandra Wudzinska, et al., bioRxiv - Synthetic Biology 2022

  Quote: ... 10 ng/ml IL-6 (Peprotech, 216-16), 10 ng/ml IL-3 (Peprotech ...
• Tumor necrosis factor is a necroptosis-associated alarmin

  Francesca Pinci, et al., bioRxiv - Immunology 2022

  Quote: ... Recombinant Murine IL-6 (Peprotech, Cat#216-16), Recombinant Murine SCF (Peprotech ...
• RTF1 mediates epigenetic control of Th17 cell differentiation via H2B monoubiquitination

  Carolina Galan, et al., bioRxiv - Immunology 2024

  Quote: ... mIL-6 (Peprotech # 216-16, 20 ng/mL) and hTGFβ1 (Peprotech # 100-21 ...
• C9orf72 repeat expansion-carrying iPSC-microglia from FTD patients show increased phagocytic activity concomitantly with decreased number of autophagosomal-lysosomal vesicles

  Hannah Rostalski, et al., bioRxiv - Neuroscience 2024

  Quote: ... 50 ng/ml IL-6 (200-06, Peprotech), 10 ng/ml IL-3 (200-03 ...
• Polyfunctional IL-21⁺ IFNγ⁺ T follicular helper cells contribute to checkpoint inhibitor diabetes mellitus and can be targeted by JAK inhibitor therapy

  Nicole Huang, et al., bioRxiv - Immunology 2024

  Quote: ... recombinant mouse IL-6 (PeproTech; 10 ng/mL) and IL-21 (PeproTech ...
• CRISPR/Cas9 knock-in strategy to evaluate phospho-regulation of SAMHD1

  Moritz Schüssler, et al., bioRxiv - Microbiology 2022

  Quote: ... 1 × 106 BlaER1 cells per well of a 6-well tissue culture plate were treated with 10 ng/ml human recombinant M-CSF and IL-3 (PeproTech) and 100 nM β-estradiol (Sigma-Aldrich ...
• Combining LSD1 and JAK-STAT inhibition targets Down syndrome-associated myeloid leukemia at its core

  Juliane Grimm, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and a cytokine cocktail (FLT3-L, SCF, IL-6, IL-3, TPO; all purchased from PeproTech, Rocky Hill, NJ, USA). Samples were taken from pediatric AML patients treated as part of the AML Berlin-Frankfurt-Münster study group ...
• A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation

  Nele Hug, et al., bioRxiv - Molecular Biology 2022

  Quote: ... supplemented with cytokines (150 ng/ml SCF, PeproTech, Cat 300-07; 150 ng/ml Flt-3, PeproTech, Cat 300-19; 10 ng/ml IL-6, PeproTech, Cat 200-06 ...