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• Use of Mucosally Administered Outer Membrane Vesicles Derived from Bordetella pertussis to Diminish Nasal Bacterial Colonization

  E. Rudi, E. Gaillard, D Bottero, D Hozbor, bioRxiv - Immunology 2024

  Quote: ... OMVs formulated with alum (Alhydrogel 2%, CRODA), c-di-AMP (7.5 µg per dose ...
• Enhanced mucosal B- and T-cell responses against SARS-CoV-2 after heterologous intramuscular mRNA prime/intranasal protein boost vaccination with a combination adjuvant

  Gabriel Laghlali, et al., bioRxiv - Immunology 2024

  Quote: ... super refined soybean oil (Croda) and water using a high-speed homogenizer as previously described.40,41 The sequence and synthesis of IVT DI RNA has previously been described in detail.17 Briefly ...
• Linear β-1,2-glucans trigger immune hallmarks and disease resistance in plants

  María Fuertes-Rabanal, et al., bioRxiv - Plant Biology 2024

  Quote: ... both treatments containing 0.05% (v/v) of Tween 24 (Croda) as adjuvant ...
• Linear β-1,2-glucans trigger immune hallmarks and disease resistance in plants

  María Fuertes-Rabanal, et al., bioRxiv - Plant Biology 2024

  Quote: ... both supplemented with 0.05% (v/v) Tween 24 (Croda) and infection with B.cinerea was performed 48 hours after the treatment ...
• Linear β-1,2-glucans trigger immune hallmarks and disease resistance in plants

  María Fuertes-Rabanal, et al., bioRxiv - Plant Biology 2024

  Quote: ... Plants were sprayed with 0.5 mL per plant of distilled water (mock) or 1 mM B2G3 both supplemented with 0.05% (v/v) Tween 24 (Croda) and were maintained in high humidity by using a cover sprayed with water ...
• Zymoseptoria tritici stealth infection is facilitated by stage-specific down-regulation of a β-glucanase

  Diego Rebaque, et al., bioRxiv - Plant Biology 2024

  Quote: ... with the adjuvants UEP-100 (0.1% v/v; Croda) and Tween 20 (0.01% v/v) ...
• Second generation of LNP based mRNA vaccine leads to a T cell–inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model

  Carole Fournier, et al., bioRxiv - Immunology 2024

  Quote: ... A second aqueous phase containing the PEGylated surfactant PEG-40 Stearate (Myrj S40, Croda Uniqema) was prepared in Phosphate-buffered saline (PBS ...
• Second generation of LNP based mRNA vaccine leads to a T cell–inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model

  Carole Fournier, et al., bioRxiv - Immunology 2024

  Quote: ... a lipid phase was prepared containing triglycerides (Suppocire NB, Gattefossé and super-refined soybean oil, Croda Uniqema) and phospholipids (Lipoid SPC3 ...
• Enhanced immunogenicity of a Clostridioides difficile TcdB vaccine adjuvanted with a synthetic dual-TLR ligand adjuvant

  Farha Naz, et al., bioRxiv - Immunology 2024

  Quote: ... Alum (Alhydrogel 2%, Croda) was diluted in water by AAHI and supplied for the immunization studies ...
• Zymoseptoria tritici stealth infection is facilitated by stage-specific down-regulation of a β-glucanase

  Diego Rebaque, et al., bioRxiv - Plant Biology 2024

  Quote: ... 0.5 mM cellotriose or the mock control (0.1% v/v UEP-100 (Croda) and 0.01% v/v Tween 20 ...
• Cell polarity control by an unconventional G-protein complex in bacteria

  Céline Dinet, et al., bioRxiv - Biochemistry 2024

  Quote: ... The oil phase was prepared by dissolving 1 mg/ml cithrol (CRODA) surfactant in Squalene oil (Mreck) ...
• Co-delivery of Paclitaxel and Cannabidiol in Lipid Nanoparticles Enhances Cytotoxicity Against Melanoma Cells

  Fabíola V. de Carvalho, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Ltda (São Paulo, SP, Brazil) and myristyl myristate (MM) was donated by Croda do Brasil Ltda (Campinas ...
• A Thermostable Tetanus/diphtheria (Td) Vaccine in the Stablevax^™ Pre-Filled Delivery System

  Juana de la Torre Arrieta, et al., bioRxiv - Immunology 2023

  Quote: ... The relationship between the adjuvant concentration and absorbance was shown to be linear using eight concentrations of Alhydrogel® (Croda Iberica SA Barcelona, Spain) from 0.02 to 2.5 mg/ml ...
• Inter-organelle crosstalk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

  Ramya S Kuna, et al., bioRxiv - Bioengineering 2023

  Quote: ... along with EquiSLASH (Avanti, Croda International Plc ...
• Novel mRNA-based VP8* vaccines against rotavirus are highly immunogenic in rodents

  Sandro Roier, et al., bioRxiv - Immunology 2023

  Quote: ... The protein vaccines were alum-adjuvanted by adsorption of the recombinant fusion proteins to aluminum hydroxide (Alhydrogel®; Croda, Frederikssund, Denmark) as previously described22 ...
• RelCoVax®, a two antigen subunit protein vaccine candidate against SARS-CoV-2 induces strong immune responses in mice

  Abhishek Phatarphekar, et al., bioRxiv - Immunology 2022

  Quote: Aluminum hydroxide gel (Alhydrogel®) or alum adjuvant was purchased from Croda, Denmark (Cat # AJV3012 ...
• Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

  Jeroen Pollet, et al., bioRxiv - Molecular Biology 2022

  Quote: ... pH 7.5 (TBS buffer) before mixing with alum (Alhydrogel®, aluminum hydroxide, Catalog # 250-843261 EP, Croda Inc., UK). CpG1826 (Invivogen ...
• Protection from Omicron and other VOCs by Bivalent S-Trimer COVID-19 Vaccine

  Danmei Su, et al., bioRxiv - Immunology 2022

  Quote: The test vaccine candidates were formulated with alum (Alhydrogel, Croda, Goole, United Kingdom) plus CpG 1018 (Dynavax Technologies ...
• 1-deoxysphingolipid biosynthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells

  Thekla Cordes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 0.1 mL of water spiked with deuterated internal standards (20 picomoles of D7-sphinganine (Avanti, Croda International Plc, 860658), 2 picomoles of D3-deoxysphinganine (Avanti ...
• 1-deoxysphingolipid biosynthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells

  Thekla Cordes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 200 picomoles of C15 ceramide-d7 (d18:1-d7/15:0) (Avanti, Croda International Plc, 860681), 100 picomoles of C13-dihydroceramide-d7 (d18:0-d7/13:0 ...
• 1-deoxysphingolipid biosynthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells

  Thekla Cordes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 2 picomoles of D3-deoxysphinganine (Avanti, Croda International Plc, 860474), 200 picomoles of C15 ceramide-d7 (d18:1-d7/15:0 ...
• 1-deoxysphingolipid biosynthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells

  Thekla Cordes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 100 picomoles of C13-dihydroceramide-d7 (d18:0-d7/13:0) (Avanti, Croda International Plc, 330726)) ...
• Intranasal Nanoemulsion Adjuvanted S-2P Vaccine Demonstrates Protection in Hamsters and Induces Systemic, Cell-Mediated and Mucosal Immunity in Mice

  Shyamala Ganesan, et al., bioRxiv - Immunology 2022

  Quote: Alum adsorbed intramuscular vaccine was prepared by mixing 2.5 μg of S-2P with 30 μg of alum (Croda, Cat# AJV3012) in a 50 μL dose volume ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... 20 picomoles of D7-sphinganine (Avanti, Croda International Plc, 860658), 2 picomoles of D3-deoxysphinganine (Avanti ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... and C15 Lactosyl(β) Ceramide-d7 (d18:1-d7/15:0) (Avanti, Croda International Plc, 330727) as internal standards ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... 400 µL saline and 100 µL of water spiked with deuterated internal standards (100 picomoles of D7-sphingosine (Avanti, Croda International Plc, 860657), 20 picomoles of D7-sphinganine (Avanti ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... were extracted from 10 µL of plasma with 750 µL of ice cold 1:1 methanol/water solution and 500 µL of ice cold chloroform with inclusion of EquiSLASH (Avanti, Croda International Plc, 330731), C15 Glucosyl(β ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... C15 Glucosyl(β) Ceramide-d7 (d18:1-d7/15:0) (Avanti, Croda International Plc, 330729), and C15 Lactosyl(β ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... (Avanti, Croda International Plc, 791649)) ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... (Avanti, Croda International Plc, 860695), 100 picomoles of glucosylceramide (d18:1-d7/15:0) ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... 100 picomoles of C13-dihydroceramide-d7 (d18:0-d7/13:0) (Avanti, Croda International Plc, 330726), 10 picomoles of glucosylsphingosine (d18:1-d7) ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... 200 picomoles of C15 ceramide-d7 (d18:1-d7/15:0) (Avanti, Croda International Plc, 860681), 100 picomoles of C13-dihydroceramide-d7 (d18:0-d7/13:0 ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... 2 picomoles of D3-deoxysphinganine (Avanti, Croda International Plc, 860474), 200 picomoles of C15 ceramide-d7 (d18:1-d7/15:0 ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... (Avanti, Croda International Plc, 330729), 100 picomoles of lactosylceramide (d18:1-d7/15:0) ...
• Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice

  Esther W. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... (Avanti, Croda International Plc, 330727), 200 picomoles of sphingomyelin (d18:1/18:1-d9) ...
• A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine

  Sonia Jangra, et al., bioRxiv - Immunology 2021

  Quote: ... super refined soybean oil (Croda) and purified water using a high speed homogenizer as previously described29 ...
• Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

  Neil C. Dalvie, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Mice were immunized IM with RBD antigen and adjuvants including aluminum Hydroxide (AlOH, Croda, Denmark), SWE11 (squalene-in-water emulsion ...
• PRE-CLINICAL IMMUNE RESPONSE AND SAFETY EVALUATION OF THE PROTEIN SUBUNIT VACCINE NANOCOVAX FOR COVID-19

  Tran Thi Nhu Mai, et al., bioRxiv - Immunology 2021

  Quote: Aluminum hydroxide gel adjuvant (alhydrogel® 1.3%) in this study was obtained commercially from Croda (Denmark) (#21645-51-2 ...
• Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection

  Lei Li, et al., bioRxiv - Immunology 2021

  Quote: ... with 1 or 5 μg rSp alone or mixed with either 1 mg Advax-SM adjuvant or where indicated 50 μg Al(OH)3 (2% Alhydrogel, Croda Denmark) in the thigh muscle at weeks 0 and 2 ...
• Tuning the immunostimulation properties of cationic lipid nanocarriers for nucleic acid delivery

  Arindam K Dey, et al., bioRxiv - Immunology 2021

  Quote: ... A second aqueous phase containing the PEGylated surfactant PEG-40 Stearate (Myrj S40, Croda Uniqema) was prepared in Phosphate-buffered saline (PBS ...
• Tuning the immunostimulation properties of cationic lipid nanocarriers for nucleic acid delivery

  Arindam K Dey, et al., bioRxiv - Immunology 2021

  Quote: ... a lipid phase was prepared containing triglycerides (Suppocire NB, Gattefossé and super-refined soybean oil, Croda Uniqema) and phospholipids (Lipoid SPC3 ...
• A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection

  Lorena M. Coria, et al., bioRxiv - Immunology 2021

  Quote: AddaVax or AddaS03 were purchased at Invivogen and Alhydrogel 2% was kindly provided by CRODA. In vaccine formulations Ag and U-Omp19 were absorbed to Alhydrogel ...
• A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection

  Lorena M. Coria, et al., bioRxiv - Immunology 2021

  Quote: ... RBD and U-Omp19 proteins were adsorbed to Alhydrogel® (CRODA, Inc.). Protein adsorption was analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis ...
• Broad neutralization against SARS-CoV-2 variants induced by a modified B.1.351 protein-based COVID-19 vaccine candidate

  Danmei Su, et al., bioRxiv - Immunology 2021

  Quote: ... All animals in Stage 1 received a priming dose (Dose 1) adjuvanted with 10 µg CpG 1018 (Dynavax) plus 75 µg Alum (aluminum hydroxide, Croda), whereas half of the animals in each group received a boost (Dose 2 ...
• Broad neutralization against SARS-CoV-2 variants induced by a modified B.1.351 protein-based COVID-19 vaccine candidate

  Danmei Su, et al., bioRxiv - Immunology 2021

  Quote: ... Alum hydroxide was manufactured under GMP by Croda. The S-Trimer subunit vaccines were mixed with the adjuvants by gentle inversion in 1:1 ratio by volume preceding each immunization.
• Evaluation of the Efficacy of Omega-3 Fatty Acids Formulations in the Lipopolysaccharide-Induced Acute Lung Inflammation Rat Model

  Chandrashekhar Kocherlakota, et al., bioRxiv - Physiology 2021

  Quote: ... The EE was a fish oil concentrate (Incromega E3322, Croda, United Kingdom) with 22% DHA and 33% EPA ...
• Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates

  Prabhu S. Arunachalam, et al., bioRxiv - Immunology 2021

  Quote: ... Alum (Alhydrogel 2%) was purchased from Croda Healthcare (Batch #0001610348) ...
• Safety and Immunogenicity Evaluation of Inactivated whole-virus-SARS-COV-2 As Emerging Vaccine Development In Egypt

  Amani A. Saleh, et al., bioRxiv - Immunology 2021

  Quote: ... or 100 μg total protein with aluminium hydroxide (Alhydrogel® CRODA health care Corp.) as adjuvant (0·45 mg/mL ...
• S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates

  Joshua G. Liang, et al., bioRxiv - Immunology 2020

  Quote: ... or 10 μg of CpG 1018 plus 50 μg of Alum (Croda). The total injection volume of the mixed vaccines (antigen + adjuvant ...
• S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates

  Joshua G. Liang, et al., bioRxiv - Immunology 2020

  Quote: ... or 1.5 mg of CpG 1018 plus 0.375 mg of Alum (Croda). The total injection volume of mixed vaccines (antigen + adjuvant ...