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1 - 50 of 2671 citations for tert Butyl 3 5 2 amino ethyl thiophen 3 yl propionate since 2020

• Atheroprone Flow Activates SMAD-FOXO1 to drive Endothelial-to-Mesenchymal Transition and Atherosclerosis

  Paul-Lennard Mendez, et al., bioRxiv - Genomics 2024

  Quote: ... SMAD2/3 (SMAD 2/3 XP, Cell Signaling Technology 8685) or isotype control (Rabbit IgG XP ...
• PAK1 and PAK2 in cell metabolism regulation

  Tereza Kořánová, et al., bioRxiv - Cell Biology 2021

  Quote: ... PAK1/2/3 (Cell Signaling, #2604), and β-actin (Sigma–Aldrich ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... PAK1/2/3 (Cell Signaling, # 2604S), pLIMK1/2 (Cell Signaling ...
• Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton

  Wenqing Zhou, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Rac1/2/3 (Cell Signaling 2465S) and secondary antibodies anti-rabbit (ThermoFisher SA5-35571) ...
• Crystal structure of a novel guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi

  Christopher Lim, et al., bioRxiv - Microbiology 2020

  Quote: ... rabbit anti-Rac1/2/3 (2465, Cell Signaling), rabbit anti-Cdc42 (2466 ...
• An Atlas of Protein Phosphorylation Dynamics During Interferon Signaling

  Idoia Busnadiego, et al., bioRxiv - Immunology 2024

  Quote: ... rabbit anti-pSer 14-3-3 Binding Motif (14-3-3 PBM) (#9601, Cell Signaling); rabbit anti-PLEKHG3 (PA5-46053 ...
• Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

  Hussam Husanie, et al., bioRxiv - Cancer Biology 2022

  Quote: ... monoclonal pSMAD 2/3 (Cell Signaling; 8828, Massachusetts, USA), monoclonal pSMAD 1/5/9 (Cell Signaling ...
• Proteomic analysis reveals complex interactions between PERK/ISR and MAPK1 in translational control in a phenotypic toxin model of Parkinson’s disease expressing PINTAC peptides

  Girish N Nallur, bioRxiv - Systems Biology 2024

  Quote: ... RSK1/2/3 (Cat. No. 9355; Cell Signaling Technology), pRPS6 (Cat ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-PAK1/2/3 (Cell Signaling 2604, 1:1000), rabbit anti-phospho-Cofilin (S3 ...
• MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

  Olaf Klingbeil, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 14-3-3 (Cell Signaling, 8312S, 1:1,000).
• Microbial Metabolite Trimethylamine N-Oxide Promotes Campylobacter jejuni Infection by Escalating Intestinal Inflammation, Epithelial Damage, and Barrier Disruption

  Caitlyn B. Smith, et al., bioRxiv - Microbiology 2024

  Quote: ... zonula occludens-3 (ZO-3) (Cell Signaling Technologies), anti-mouse IgG (Alexa Fluor® 488 ...
• Loss of PRICKLE1 in the myometrium leads to reduced fertility, abnormal myometrial architecture, and aberrant extracellular matrix deposition in mice

  Emily R Roberts, et al., bioRxiv - Physiology 2024

  Quote: ... anti-RAC1/2/3 (Cell Signaling Technology, Cat# 2465P, 1:1000), anti-RHOA (Cell Signaling Technology ...
• Microbial Metabolite Trimethylamine N-Oxide Promotes Campylobacter jejuni Infection by Escalating Intestinal Inflammation, Epithelial Damage, and Barrier Disruption

  Caitlyn B. Smith, et al., bioRxiv - Microbiology 2024

  Quote: ... and zonula occludens-3 (ZO-3) (Cell Signaling Technologies).
• Obesogenic diet in mice leads to inflammation and oxidative stress in the mother in association with sex-specific changes in fetal development, inflammatory markers and placental transcriptome

  Alejandro A. Candia, et al., bioRxiv - Physiology 2023

  Quote: ... 3-nitrotyrosine (3-NT, #9691 Cell signaling, 1:10000), 4-hydroxynonenal (4HNE ...
• Missense and nonsense mutations of the zebrafish hcfc1a gene result in contrasting mTor and radial glial phenotypes

  Victoria L. Castro, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 14-3-3-beta/alpha (Cell Signaling Cat # 9636S) (anti-rabbit ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... 14-3-3 (pan) E9S9M Rabbit mAb (Cell Signaling Technology), and Purified Mouse Anti-MEK1 Clone 25/MEK1 (BD Biosciences).
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PAK 1/2/3 1:1000 (Cell Signaling Technology Cat# 2604, RRID:AB_2160225), Myc-Tag 1:1000 (Cell Signaling Technology Cat# 2276 ...
• Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

  Ferrol I. Rome, et al., bioRxiv - Physiology 2022

  Quote: ... and 3-hydroxymethylglutaryl-CoA synthase 2 (HMGCS2; Cell Signaling Technology, 20940S; RRID:AB_2798853). All primary antibodies were used as a dilution of 1:1000 ...
• Alternative splicing in neuroblastoma generates RNA-fusion transcripts and is associated with vulnerability to spliceosome inhibitors

  Yao Shi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Caspase-3 (14220s) and cleaved caspase-3 (9664s) from Cell Signaling.
• Integrated glycoproteomics identifies a role of N-glycosylation and galectin-1 on myogenesis and muscle development

  Ronnie Blazev, et al., bioRxiv - Biochemistry 2020

  Quote: ... and pan 14-3-3 loading control (#8312; Cell Signaling Technologies). Detection was achieved with HRP-conjugated donkey anti-rabbit secondary antibody (Jackson ImmunoResearch ...
• Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant

  Nghi D. P. Dang, et al., bioRxiv - Neuroscience 2024

  Quote: ... stained for 2-3 days with the total ERK antibody (Cell Signaling, #4696) and phospho-Erk antibody (Cell Signaling #4370) ...
• Amyloid β induces cardiac dysfunction and neuro-signaling impairment in the heart of an Alzheimer’s disease model

  Andrea Elia, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Cleaved Caspase-3-Asp175 (Cl-Casp-3-Cell Signaling-#94530; 1:200), dopamine β hydroxylase (DβH ...
• 14-3-3 protein augments the protein stability of phosphorylated spastin and promotes the recovery of spinal cord injury through its agonist intervention

  Qiuling Liu, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Pan 14-3-3 (1:1000, #8312 from Cell Signaling Technology), anti-Pan phosphoserine/threonine (Cat#612548 form BD life science ...
• Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic cellular program

  Caitlan D. Byerly, et al., bioRxiv - Microbiology 2022

  Quote: ... α-Caspase 3 (Cell Signaling), α-Caspase 9 (Sell Signaling) ...
• Dkk1 inhibition normalizes limb phenotypes in a mouse model of Fzd2 associated omodysplasia Robinow syndromes

  Ryan P. Liegel, et al., bioRxiv - Developmental Biology 2022

  Quote: ... incubated overnight with Cleaved Caspase-3 (CC-3; Cell Signaling 9661S; 1:300) or phospho-Histone H3 (pHH3 ...
• Amyloid β induces cardiac dysfunction and neuro-signaling impairment in the heart of an Alzheimer’s disease model

  Andrea Elia, et al., bioRxiv - Molecular Biology 2023

  Quote: ... or cleaved caspase-3 (Asp175) (Cl-Casp-3, Cell Signaling, #94530; 1:200) antibodies ...
• Protective Role of RIPK1 Scaffolding against HDV-Induced Hepatocyte cell death and the Significance of Cytokines in Mice

  Gracián Camps, et al., bioRxiv - Pathology 2023

  Quote: ... cleaved Caspase-3 (activated Caspase 3 (a-Casp3)) (Cell Signaling 9661, 1:200) (Table 1) ...
• ROSALIND protects the mitochondrial translational machinery from oxidative damage

  Vicky Katopodi, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and Caspase 3/7 (1:300) [Cleaved Caspase-3 (Asp175) (5A1E) (Cell Signaling)] ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: 14-3-3 (pan) E9S9M Rabbit mAb (Cell Signaling Technology, cat. no. 95422)
• SUMO Modifies GβL and Mediates mTOR Signaling

  Sophia Louise Lucille Park, et al., bioRxiv - Biochemistry 2020

  Quote: ... SUMO-1 (4930) and SUMO-2/3 (4971) were obtained from Cell Signaling Technology. 6x-His tag Antibody (MA1-125 21315 ...
• Prenatal exposure to valproic acid induces sex-specific alterations in cortical and hippocampal neuronal structure and function in rats

  Olivia O. F. Williams, et al., bioRxiv - Neuroscience 2024

  Quote: ... or phospho-GSK-3 α/β (GSK-3 α/β, 1:10,000, rabbit-#5676, Cell Signaling; phospho-GSK-3 α/β (Ser21/9), 1:10,000 ...
• ROSALIND protects the mitochondrial translational machinery from oxidative damage

  Vicky Katopodi, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and for Caspase 3/7 1:300 [Cleaved Caspase-3 (Asp175) (5A1E) (Cell Signaling)] ...
• Dual-Targeted Microbubbles Promote Apoptosis of M1 Macrophages by Inhibiting Telomerase Activity for Atherosclerosis Therapy

  Wei Zeng, et al., bioRxiv - Bioengineering 2024

  Quote: ... Caspase-3 and Cleaved Caspase-3 were purchased from Cell Signaling Technology (Boston, USA). Antibodies against TERT were purchased from Proteintech Group (Wuhan ...
• Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

  Anna L Koessinger, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Caspase 3 (Cell Signaling #9662), cleaved Caspase 3 (Cell Signaling #9664) ...
• Latrophilins are essential for endothelial junctional fluid shear stress mechanotransduction

  Keiichiro Tanaka, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Anti-Smad2/3 (Cell signaling) (8685) ...
• Differential antitumor activity of compounds targeting the ubiquitin-proteasome machinery in gastrointestinal stromal tumor (GIST) cells

  Jessica L. Rausch, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cleaved caspase 3 (Cell Signaling), CREB binding protein (CBP ...
• Profiling anti-apoptotic protein BCL-xL expression in U-87 MG glioblastoma cells and patient-derived tumorspheres

  D. Fanfone, M. Gabut, G. Ichim, bioRxiv - Cancer Biology 2020

  Quote: ... Caspase-3 (Cell Signaling, 9662S). Membranes were rinsed 3×10 minutes in TBST 0.1% then incubated with appropriate secondary antibody coupled to the horseradish peroxidase (Biorad ...
• Targeting the translational machinery in gastrointestinal stromal tumors (GIST) – a new therapeutic vulnerability

  Donna M. Lee, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved caspase 3 (Cell Signaling), cyclin A (Novocastra) ...
• SMARCA4 supports the oncogenic landscape of KRAS-driven lung tumors

  Shivani Malik, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cleaved caspase 3 (Cell Signaling), Ki67 (Abcam) ...
• Coordination of two enhancers drives expression of olfactory trace amine-associated receptors

  Aimei Fei, et al., bioRxiv - Neuroscience 2020

  Quote: ... caspase-3 (Cell Signaling, 9661), GFP (Abcam ...
• Exacerbation of mitochondrial fission in human CD34⁺ cells halts erythropoiesis and hemoglobin biosynthesis

  Alvaro M. Gonzalez-Ibanez, et al., bioRxiv - Cell Biology 2020

  Quote: ... Caspase-3 (9665, Cell Signaling), Caspase-8 (sc-5263 ...
• TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection

  Tzvi Pollock, et al., bioRxiv - Microbiology 2022

  Quote: ... caspase-3 (#9662; Cell Signaling), caspase-8 (#4798 ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... CASPASE 3 (9662, Cell Signaling), CASPASE 9 (9502 ...
• Yersinia remodels epigenetic histone modifications in human macrophages

  Indra Bekere, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-caspase-3 (Cell Signaling) at 1:1000 ...
• Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

  Deborah Fanfone, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Caspase-3 (Cell Signaling, 9662S), GFP (Life ...
• Regnase-1 deficiency restrains Klebsiella pneumoniae infection by regulation of a Type I interferon response

  Giraldina Trevejo-Nuñez, et al., bioRxiv - Immunology 2021

  Quote: ... total caspase 3 (Cell Signaling) and beta-actin (Abcam).
• Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells

  Xiaolong Wei, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cleaved caspase-3 (Cell Signaling), and anti-β-actin (Sigma) ...
• Hypoxia-induced SETX links replication stress with the unfolded protein response

  Shaliny Ramachandran, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cleaved caspase 3 (Cell Signaling) and BrdU (BD Biosciences ...
• Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein

  Andrew Shum, et al., bioRxiv - Neuroscience 2022

  Quote: ... Caspase-3 (Cell Signaling, 9662), p53 (Santa Cruz ...
• A UL26-PIAS1 complex antagonizes anti-viral gene expression during Human Cytomegalovirus infection

  Jessica Ciesla, et al., bioRxiv - Molecular Biology 2024

  Quote: ... SUMO2/3 (Cell Signaling, #4971S), viral proteins IE1(69) ...