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1 - 50 of 132 citations for n1 Alpha L arabinopyranosylamino guanidine hno3 since 2020

• Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models

  Lily L. Nguyen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... alpha-tubulin (Cell Signaling Cat ...
• Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development

  Kenjiroo Matsumoto, et al., bioRxiv - Biochemistry 2024

  Quote: ... human N1 ICD (1/1000, #D1E11, Cell Signaling), Tubulin (1/5000 ...
• Targeting LDHC dysregulates the cell cycle and improves sensitivity to cisplatin and olaparib

  Adviti Naik, Julie Decock, bioRxiv - Cancer Biology 2021

  Quote: ... acetylated alpha-tubulin (Cell Signaling), MAP1B (Abcam) ...
• LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation

  Francesca Pischedda, et al., bioRxiv - Neuroscience 2020

  Quote: ... alpha-Synuclein (D37A6-Cell Signaling); LC3 (NB100-2331-Novus Biologicals) ...
• ZDHHC5 targets Protocadherin 7 to the cell surface by a palmitoylation-dependent mechanism to promote successful cytokinesis

  Nazlı Ezgi Özkan Küçük, et al., bioRxiv - Cell Biology 2022

  Quote: ... Alpha Tubulin (Cell Signaling, 3873S), Tubulin (Abcam ...
• Spheroid architecture strongly induces miR-221/222 expression and promotes oxidative phosphorylation and survival of mobile tumor cells through a mechanism that includes restriction of miR-9 expression

  Avery S. Ward, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Alpha-tubulin (Cell Signaling, 2144); Citrate synthetase (Abcam ...
• A conformational switch driven by phosphorylation regulates Ykt6 activity in macroautophagy

  Kaitlyn McGrath, et al., bioRxiv - Cell Biology 2020

  Quote: ... alpha/beta-Tubulin (Cell Signaling, 2148S), and STX7 (Bethyl ...
• Targeting a proteolytic neo-epitope of CUB-domain containing protein 1 in RAS-driven cancer

  Shion A. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... alpha-Tubulin(DM1A) (Cell Signaling, 3873S), IRDye 680RD Goat anti-Mouse (LiCOR ...
• Intrinsic BMP inhibitor Gremlin regulates lung alveolar progenitor cell proliferation and differentiation

  Toyoshi Yanagihara, et al., bioRxiv - Molecular Biology 2022

  Quote: ... alpha-Tubulin (#2144S, Cell Signaling Technology), PCNA (#2586S ...
• Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation

  Elizabeth M. Black, et al., bioRxiv - Cell Biology 2024

  Quote: ... alpha tubulin (Cell Signaling Technology, 3873), Chk2 (Cell Signaling Technology ...
• Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth

  Emilie Abby, et al., bioRxiv - Cancer Biology 2021

  Quote: ... alpha-TUBULIN (Cell signaling, catalog no. 2125).
• Drosophila p38 MAPK Interacts with BAG-3/starvin to Regulate Age-dependent Protein Homeostasis

  Sarah M. Ryan, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-alpha tubulin (Cell Signaling Technologies), mouse anti-Lamin 1:100 (DHSB) ...
• Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity

  Melica Nourmoussavi Brodeur, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Alpha-tubulin (2144S, Cell Signaling; 1:1000) and vinculin (sc-73614 ...
• Histone H1.2 Dependent Translocation of Poly (ADP-ribose) Initiates Parthanatos

  Jing Fan, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-alpha-Tubulin (#2144, Cell signaling), horse radish peroxidase (HRP ...
• Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates

  Donghwi Bae, et al., bioRxiv - Cell Biology 2022

  Quote: ... alpha-TUBULIN (Cell Signaling 2144, 1:25), LAMP (DSHB ...
• Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism

  Nicholas L. Arp, et al., bioRxiv - Biochemistry 2023

  Quote: ... Anti-alpha-tubulin (Cell Signaling Technology, 3873S), Anti-beta-actin (Cell Signaling Technology ...
• Tuning of granulopoietic signaling by de novo designed agonists

  Timo Ullrich, et al., bioRxiv - Bioengineering 2024

  Quote: ... alpha-tubulin 1:1000 (Cell Signaling, #2144S), primary rabbit monoclonal antibodies against ...
• Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis

  Rachana R. Chandran, et al., bioRxiv - Pathology 2024

  Quote: ... Acetyl Alpha Tubulin-555 (58241S, Cell Signaling), anti-KRT5 (905901 ...
• Novel inhibitors of acute, axonal DLK palmitoylation are neuroprotective and avoid the deleterious side effects of cell-wide DLK inhibition

  Xiaotian Zhang, et al., bioRxiv - Neuroscience 2024

  Quote: ... alpha-tubulin (mouse, Cell Signaling Technology, #3873), phospho-MKK4 (rabbit ...
• Identification of proximal SUMO-dependent interactors using SUMO-ID

  Orhi Barroso-Gomila, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-alpha-Actinin (1/5000) (Cell Signaling Technology); anti-Flag (1/1000) ...
• Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

  Jaspreet K. Osan, et al., bioRxiv - Microbiology 2020

  Quote: ... acetylated-alpha-tubulin (1:500) (Cell Signaling Technologies) for the staining of ciliated cells ...
• Nuclear SUN1 Stabilizes Endothelial Cell Junctions via Microtubules to Regulate Blood Vessel Formation

  Danielle B Buglak, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-alpha-tubulin (1:500, 3873S, Cell Signaling), anti-GEF-H1 (1:500 ...
• LncRNA PAINT is Associated with Aggressive Prostate Cancer and Dysregulation of Slug and Related Genes

  Md Faqrul Hasan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... alpha-tubulin and anti-GAPDH (Cell Signaling Technology), and anti-PCNA (Santa Cruz) ...
• Impaired migration and premature differentiation underlie the neurological phenotype associated with PCDH12 loss of function

  Jennifer Rakotomamonjy, et al., bioRxiv - Neuroscience 2023

  Quote: ... alpha-Tubulin (1:1000, Cell Signaling Technology, 2144), N-cadherin (1:1000 ...
• Immortalization and transformation of primary cells mediated by engineered ecDNAs

  Davide Pradella, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-alpha-tubulin (1:5000, Cell Signaling, #3873), anti-p53 (1:1000 ...
• Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

  Weini Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... I-κB alpha (Cell Signaling Technologies, cat #4176), histone H3 (Cell Signaling Technologies ...
• ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle

  Antentor Hinton Jr., et al., bioRxiv - Biophysics 2023

  Quote: ... Alpha Tubulin (1:1000; Cell Signaling Technology; #2144), and IP3R3 (1:1000 ...
• Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase

  Herschel S. Dhekne, et al., bioRxiv - Biochemistry 2023

  Quote: ... Mouse anti-alpha tubulin (Cell Signaling Technologies, 3873S), Rat anti-HA tag (cat #11867423001 ...
• Elevated plasma and urinary erythritol is a biomarker of excess simple carbohydrate intake in mice

  Semira R. Ortiz, Martha S. Field, bioRxiv - Biochemistry 2022

  Quote: ... and alpha-tubulin (1:1,000, Cell Signaling Technology). Secondary anti-rabbit antibody (1:100,000 ...
• Compound screening in primary human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies

  Yuki Ishii, et al., bioRxiv - Cell Biology 2024

  Quote: ... or anti-alpha-tubulin (9099, Cell Signaling Technologies) antibodies ...
• AVJ16 inhibits the RNA binding protein IGF2BP1 in lung adenocarcinomas and prevents tumor growth in mice

  Nadav Wallis, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-alpha/beta tubulin (Cell Signaling 2148), goat anti-rabbit IgG-HRP (Jackson) ...
• Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions

  Ibrahim AlZaim, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-alpha-SMA (19245, Cell Signaling Technology), rabbit anti-PDGFRB (MA5-15143 ...
• Obesity Disrupts Pituitary UPR Leading to NAFLD

  Qingwen Qian, et al., bioRxiv - Physiology 2022

  Quote: ... IRE1 alpha (Cell Signaling, Cat No. 3294, 1:300), sXBP1 (Cell Signaling ...
• Missense and nonsense mutations of the zebrafish hcfc1a gene result in contrasting mTor and radial glial phenotypes

  Victoria L. Castro, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 14-3-3-beta/alpha (Cell Signaling Cat # 9636S) (anti-rabbit ...
• Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation

  Nicholas M. Cronin, et al., bioRxiv - Cell Biology 2024

  Quote: ... monoclonal AMPK-alpha at 1:1000 (Cell Signaling; 2532), monoclonal Ser-1177 phospho-eNOS at 1:500 (Cell Signaling ...
• A predominately pulmonary activation of complement in a mouse model of severe COVID-19

  Peter J. Szachowicz, et al., bioRxiv - Immunology 2024

  Quote: ... anti-alpha-tubulin (1:200, cat#5335S, Cell Signaling), anti-HopE1 (1:100 ...
• A conserved germline-specific Dsn1 alternative splice isoform supports oocyte and embryo development

  Jimmy Ly, et al., bioRxiv - Cell Biology 2024

  Quote: ... and Alpha Tubulin-conjugated 488 (Rabbit, Cell Signaling; S063S) for 1 hour in a dark ...
• SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport through interactions with Rae1 and Nup98

  Amin Addetia, et al., bioRxiv - Microbiology 2020

  Quote: ... and 1:1,000 anti-alpha Tubulin (Cell Signaling; clone DM1A), which was followed by staining with either 1:10,000 IRDye 680RD anti-Mouse IgG secondary antibody (Licor ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-alpha tubulin (Cell Signaling, #2144, 1:10000), followed by blotting with secondary antibodies peroxidase-conjugated goat anti-rabbit IgG (Jackson Lab ...
• Oncogenic BRAF Induces Whole-Genome Doubling Through Suppression of Cytokinesis

  Revati Darp, et al., bioRxiv - Cancer Biology 2021

  Quote: ... alpha-Tubulin (Cell Signaling Technology 9154, 8727, 4695, 3873, respectively); pERK (Sigma m8159) ...
• Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells

  Paul O’Callaghan, et al., bioRxiv - Cell Biology 2020

  Quote: ... and alpha (α)-tubulin (11H19) rabbit mAb (Cell Signaling Technology) were detected with Alexa Fluor goat anti-rabbit IgG secondary antibodies conjugated to 680 nm fluorophores nm ...
• A microtubule stability switch alters isolated vascular smooth muscle calcium flux in response to matrix rigidity

  Robert Johnson, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-total alpha tubulin (Cell Signaling Technology Cat#3873, RRID:AB_1904178), anti-HDAC6 (D2E5 ...
• Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

  Jaspreet K. Osan, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-acetyl-alpha-tubulin rabbit monoclonal (1:500) (Cell Signaling Technologies), anti-TMPRSS2 mouse monoclonal (1:50 ...
• A high-content screen identified ingenol-3-angelate as an enhancer of B7-H3-CAR T cell activity by increasing B7-H3 protein expression on the target cell surface via PKCα activation

  Ha Won Lee, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or 1:1000 anti-PKC-alpha antibody (Cell Signaling Technology, 2056S) with or without 1:10,000 anti-beta actin (Sigma ...
• Up-regulation of cholesterol synthesis by lysosomal defects requires a functional mitochondrial respiratory chain

  Francesco Agostini, et al., bioRxiv - Biochemistry 2024

  Quote: ... rabbit SGK3-alpha/beta phosphor S21/S9 (Cell signaling technology, D8SeE12), PDI (Cell signaling technology ...
• A microtubule stability switch alters isolated vascular smooth muscle calcium flux in response to matrix rigidity

  Robert Johnson, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-acetyl K40 alpha tubulin (Cell signaling technology Cat #3971, RRID:AB_2210204), anti-total alpha tubulin (Cell Signaling Technology Cat#3873 ...
• Sex specific effects of environmental toxin-derived alpha synuclein on enteric neuronal-epithelial interactions

  Hayley N Templeton, et al., bioRxiv - Physiology 2024

  Quote: ... at 1:500 and anti-alpha-Synuclein (Cell Signaling, Danvers, MA) at 1:500 in PBS containing 5% NGS and 0.3% Tx ...
• A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone

  Lisonia Gkioni, et al., bioRxiv - Physiology 2024

  Quote: ... with alpha tubulin (1:1000, anti-rabbit, Cell Signaling Technology, 2125) as internal control and normalised against non-drug treated controls.
• An endometrial organoid model of Chlamydia-epithelial and immune cell interactions

  Lee Dolat, Raphael H. Valdivia, bioRxiv - Cell Biology 2020

  Quote: ... anti-acetylated-alpha-tubulin (Cell Signaling Technologies, Cat no. 5335S 1:200), anti-SEPT2 (Protein Tech ...
• Chromosome length and gene density contribute to micronuclear membrane stability

  Anna E Mammel, et al., bioRxiv - Cell Biology 2021

  Quote: ... Primary antibodies used: mouse alpha-tubulin (1:250; 3873S, Cell Signaling Technology), human anti-CREST (1:100 ...