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251 - 300 of 1680 citations for 6 CHLORO 3 METHYLPYRIDO 3 4 D PYRIMIDIN 4 3H ONE since 2019

• Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

  Shinya Matsuda, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-Cleaved Caspase-3 (1:500; Cell Signaling). All the primary and secondary antibodies were diluted in 5% normal goat serum (NGS ...
• Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

  H.C. Dahl, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cleaved Caspase 3 (Cell Signaling, Danvers, MA; 9664S). Secondary antibodies ...
• Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice

  Calli Bennett, et al., bioRxiv - Neuroscience 2021

  Quote: ... or anti-active caspase-3 (Cell Signaling, 9662) at 1:100 ...
• Defective myelination in an RNA polymerase III mutant leukodystrophic mouse

  Emilio Merheb, et al., bioRxiv - Neuroscience 2021

  Quote: ... Cleaved Caspase-3 (Cell Signaling 9664; 1:1000), MBP (abcam 7349 ...
• The solute carrier MFSD1 decreases β1 integrin’s activation status and thus tumor metastasis

  Marko Roblek, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-cleaved caspase 3 (Cell Signaling Technology, #9661S), Streptavidin-HRP (ThermoFisher Scientific ...
• Regulation of neuronal progenitor delamination by dynein-driven post-Golgi apical transport

  J.B. Brault, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-cleaved-Caspase 3 (Cell Signaling, 9661S), rabbit anti-RAB6A/A’ (home-made65) ...
• Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice

  Alexandra I. Wells, et al., bioRxiv - Microbiology 2020

  Quote: ... and cleaved caspase 3 (Asp175) (9661, Cell Signaling).
• Crystal structure of a novel guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi

  Christopher Lim, et al., bioRxiv - Microbiology 2020

  Quote: ... rabbit anti-Rac1/2/3 (2465, Cell Signaling), rabbit anti-Cdc42 (2466 ...
• Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following demyelination

  Darpan Saraswat, et al., bioRxiv - Neuroscience 2020

  Quote: ... cleaved caspase-3 (Asp175) (1:250, Cell signaling), and rabbit anti-NG2 (1:200 ...
• Interleukin-22 mediated renal metabolic reprogramming via PFKFB3 to treat kidney injury

  Wei Chen, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... Capase-3 were purchased from Cell Signaling Technology, USA ...
• Annexin A1 tripeptide mimetic increases sirtuin-3 to augment mitochondrial function and limit ischemic kidney injury

  Hagir Suliman, et al., bioRxiv - Physiology 2020

  Quote: ... sirtuin 3 (#5490S, Cell Signaling Technologies, Danvers, MA).
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cleaved Caspase-3 (Cell Signaling, 9661s, 1:500), HIF1 alpha (Abcam ...
• P53-independent restoration of p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9

  Xiaobing Tian, et al., bioRxiv - Cancer Biology 2020

  Quote: ... DR5 and cleaved Caspase 3 (Cell Signaling Technology), ATF4 (Abcam).
• The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains

  Carlos Gomez-Diaz, et al., bioRxiv - Cell Biology 2021

  Quote: ... cleaved caspase-3 (Cell Signaling, 9661, 1:100), Ly6G (Abcam ...
• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... Cleaved Caspase 3 (Cell Signaling #9661, 1/1000). HRP-conjugated goat anti-mouse and goat anti-rabbit antibodies (DAKO ...
• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... Cleaved Caspase 3 (Cell Signaling #9661, 1/1000) antibody was used to assess cell death followed by Alexa fluor 563 coupled secondary antibodies ...
• Cancer cells induce hepatocytes apoptosis in co-opted colorectal cancer liver metastatic lesions

  Miran Rada, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved caspase-3 1:500 (Cell signaling, # 9664S) and cleaved PARP-1 1:500 (Cell signaling ...
• Beta HPV8 E6 Induces Micronuclei Formation and Promotes Chromothripsis

  Dalton Dacus, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Cleaved Caspase-3 (Asp175) (9661S, Cell Signaling Technology). The cells were washed and stained with the appropriate secondary antibodies ...
• NEDD8 activity is important for direct antigen MHC class I antigen presentation

  Kartikeya Vijayasimha, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-NEDD8 (Cell Signaling 2745S, Lot#3). Infrared dye-coupled secondary antibodies (goat anti-mouse or goat anti-rabbit ...
• Innovative multidimensional models in a high-throughput-format for different cell types of endocrine origin

  Stefan Bornstein, et al., bioRxiv - Cancer Biology 2022

  Quote: ... cleaved caspase 3 (1:300, 9661, Cell Signaling), insulin (1:200 ...
• TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

  Jifan Feng, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Five μl of Smad2/3 (8685, Cell Signaling) or IgG (3900 ...
• Substance P and adenosine signaling pathways regulate exosomal sorting of miR-21 in colonic epithelial cells

  Sameena Wani, et al., bioRxiv - Cell Biology 2022

  Quote: ... Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (Cell Signaling Technology) and anti-actin (Sigma Aldrich ...
• Ciliopathic micrognathia is caused by aberrant skeletal differentiation and remodeling

  Christian Louis Bonatto Paese, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Cleaved Caspase-3 (1:100, Cell Signaling 9661) and Phospho-Histone H3 (1:200 ...
• POMC-specific knockdown of Tril reduces body adiposity and increases hypothalamic leptin responsiveness

  Alexandre Moura-Assis, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-cleaved caspase-3 (Cell Signaling, #9661S), rabbit anti-POMC (Phoenix Pharmaceuticals ...
• Dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke in middle aged male and female mice

  Gyllian B. Yahn, et al., bioRxiv - Neuroscience 2022

  Quote: ... active caspase-3 (1:100, Cell Signaling Technologies) to measure apoptosis and phospho-AKT (protein kinase B ...
• Doxycycline Significantly Enhances Induction of iPSCs to Endoderm by Enhancing survival via AKT Phosphorylation

  Cristina Esteva-Font, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Cleaved Caspase-3 (Cell Signaling, #9661, 1:400)) in blocking solution ...
• Aicardi-Goutières Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

  Sarah K Deasy, et al., bioRxiv - Cancer Biology 2019

  Quote: ... cleaved caspase 3 (1:1000; Cell Signaling #9661), p21 (1:333 ...
• Activation of Smad 2/3 signaling by low shear stress mediates artery inward remodeling

  Elizabeth Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... Smad 2/3 (1:1000; Cell Signaling; #8685S), P-Smad 1/5/8 (1:1000 ...
• A functional pre-screening platform for identifying points of vulnerability in the cell death map of human melanoma tumors

  Naama Pnina Dekel-Bird, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cleaved caspase-3 (cat#C-9664) (Cell Signaling), or Mcl-1 (Santa Cruz ...
• Murine cytomegaloviruses m139 targets DDX3 to curtail interferon production and promote viral replication

  Olha Puhach, et al., bioRxiv - Microbiology 2020

  Quote: ... glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (14C10; Cell Signaling), DDX3 (C-4 ...
• Gα13 loss promotes tumor progression in the KPC transgenic mouse model of advanced pancreatic cancer

  Mario A. Shields, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved caspase-3 (Cell Signaling #9664, 1:800), MTOR (Cell Signaling #2983 ...
• Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis

  Ashley Boice, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-caspase-3 (polyclonal from Cell Signaling Technology), anti-actin (C4 from MP Biomedicals) ...
• Site-specific ubiquitination of the E3 ligase HOIP regulates cell death and immune signaling

  Lilian M. Fennell, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-cleaved Caspase 3 antibody (Cell Signaling, #9664), anti-FADD antibody used for immunoprecipitation (Santa Cruz ...
• Coordinated activation of both TGFβ and BMP canonical pathways regulates autophagy and tissue regeneration in acetaminophen induced liver injury

  Athanasios Stavropoulos, et al., bioRxiv - Physiology 2021

  Quote: ... rabbit anti- Cleaved Caspase-3 (Cell Signaling, 9661), rabbit anti-p62 (MBL ...
• Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes

  Madeline G. Andrews, et al., bioRxiv - Neuroscience 2021

  Quote: ... Cleaved Caspase-3 (Cell Signaling, 9661S, 1:250), Synm (Proteintech ...
• β-Catenin-NFκB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

  Shikai Hu, et al., bioRxiv - Pathology 2021

  Quote: ... Cleaved Caspase 3 (Cell Signaling, 9664, 1:100), p-Erk1/2 (Cell Signaling ...
• Age-related neurodegeneration and cognitive impairments of NRMT1 knockout mice are preceded by misregulation of RB and expansion of the neural stem cell population

  James Catlin, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-cleaved caspase-3 (Cell Signaling Technologies), rabbit anti-Doublecortin (Abcam) ...
• Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities

  Maryam Yousefi, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved caspase 3 Antibody (Cell Signaling Technology, 9669), and Click-iT™ EdU Alexa Fluor™ 647 Flow Cytometry Assay Kit (Thermo Fisher Scientific ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved Caspase-3 (Asp175) (Cell Signaling Technology, 9661), cleaved Caspase-7 (Asp198 ...
• Genome-wide characterization of SARS-CoV-2 cytopathogenic proteins in the search of antiviral targets

  Jiantao Zhang, et al., bioRxiv - Molecular Biology 2021

  Quote: ... rabbit anti-Cleaved-Caspase 3 (Cell signaling: 9664) and mouse anti-GAPDH antibody (Cell signaling ...
• Tumor genotype dictates radiosensitization after Atm deletion in brainstem gliomas

  Katherine M. Deland, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cleaved Caspase-3 (Cell Signaling, 9661S, 1:1,000), NQO1 (Abcam ...
• Mitochondria regulate Drosophila intestinal stem cell differentiation through FOXO

  Fan Zhang, Mehdi Pirooznia, Hong Xu, bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-Cleaved Caspase-3 (9661, Cell signaling); rabbit anti-FOXO antibody (ab195977 ...
• Cancer cells induce hepatocytes apoptosis in co-opted colorectal cancer liver metastatic lesions

  Miran Rada, et al., bioRxiv - Cancer Biology 2021

  Quote: ... leaved caspase-3 1:100 (Cell signaling, # 9664S), cleaved PARP-1 1:50 (Cell signaling ...
• Activation of GSDME compensates for GSDMD deficiency in a mouse model of NLRP3 inflammasomopathy

  Chun Wang, et al., bioRxiv - Immunology 2021

  Quote: ... caspase-3 (1:1,000; Cell Signaling Technologies, MA), p38 MAPK (1:1,000 ...
• Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis

  Christopher Brereton, et al., bioRxiv - Cell Biology 2021

  Quote: ... p-Smad2/3 (1:1000, Cell Signaling Technology), p-ERK (1:1000 ...
• Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring

  McCoy Clementson, et al., bioRxiv - Neuroscience 2022

  Quote: ... active caspase-3 (1:100, Cell Signaling Technologies) to measure apoptosis ...
• Germline protein, Cup, non-cell autonomously limits migratory cell fate in Drosophila oogenesis

  Banhisikha Saha, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Phosho histone 3 antibody (Cell Signaling Technology, 9713S) was used at 1:150 dilutions ...
• Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity

  Aparajitha Vaidyanathan, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Argonaute-3 (1:1000) (Cell Signaling #5054), anti-Argonaute-4 (1:1000 ...
• Rapid proteostasis controls monolayer integrity of quiescent endothelium

  Fabienne Podieh, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-cleaved caspase 3 (#9661, Cell Signaling Technology), anti-GAPDH (#2118 ...
• DiPRO1 dependent transcriptional and epigenetic regulation distinctly controls the fate of muscle and mesenchymal cancer cells

  Jeremy Rich, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-cleaved caspase 3 (1/100) (Cell Signaling), visualized using the polink anti rat kit (GBI Labs ...