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• 1-deoxysphingolipid biosynthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells

  Thekla Cordes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Cells were then incubated with primary anti-RAB5 antibody at 4 °C overnight diluted in 8% BSA in PBST (1:500 dilution, Cat. #3547, lot 7, Cell Signaling Technology). Secondary anti-rabbit Alexa Fluor 568 antibody (1:1000 dilution ...
• HCP5 prevents ubiquitination-mediated UTP3 degradation to inhibit apoptosis by activating c-Myc transcriptional activity

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... cleaved Caspase-7 (1:1000, Cell Signaling Technology, #8438), cleaved PARP (1:1000 ...
• Epsilon tubulin is an essential determinant of microtubule-based structures in male germ cells

  G. Gemma Stathatos, et al., bioRxiv - Developmental Biology 2023

  Quote: ... cleaved Caspase 7 (9491, Cell Signaling Technology, 1:500), KATNA1 ...
• Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor

  Patricia D.B. Tiburcio, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cleaved Caspase-7 (Cell Signaling Technology 8438, RRID:AB_11178377; 1:1,000), Caspase-9 (Cell Signaling Technology 9508 ...
• Chronic optogenetic activation of hippocampal pyramidal neurons replicates the proteome footprint of Alzheimer’s disease-like pathology

  Iason Keramidis, et al., bioRxiv - Neuroscience 2023

  Quote: ... in PBST and then incubated for 15 hrs at 4 °C in primary anti-c-Fos (rabbit monoclonal, 1:2000, Cell Signaling 2250) diluted in PBST containing 4% NGS ...
• Apoptotic signaling clears engineered Salmonella in an organ-specific manner

  Taylor J. Abele, et al., bioRxiv - Immunology 2023

  Quote: ... cleaved caspase-7 (1:1000, rabbit, Cell Signaling Technology, Cat. 9491), cleaved caspase-3 (1:750 ...
• Harbingers of Aggressive Prostate Cancer: Precision Oncology Case Studies

  Joanna Cyrta, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p53 (Cell Signaling Technologies, clone DO-7, 1/100, H1, 20min).
• Characterisation of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

  Caroline Frørup, et al., bioRxiv - Cell Biology 2022

  Quote: ... Antibodies used were anti-cleaved caspase-7 (#9491S, Cell Signaling, 1:500), anti-MHC-I (#ALX-805-711-C100 ...
• Epigenetic plasticity via adaptive DNA hypermethylation and clonal expansion underlie resistance to oncogenic pathway inhibition in pancreatic cancer

  Laura K. Godfrey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p-ERK1/2 (#4376, RRID:AB_331772, Cell Signaling Technology, 1:15), Vinculin (#13901 ...
• Caspase3-deficient cells require fibronectin for protection against autophagy-dependent death

  David B. Weir, Lawrence H. Boise, bioRxiv - Cell Biology 2021

  Quote: ... Caspase-7 (Cell Signaling), Fibronectin (Abcam) ...
• ROSALIND protects the mitochondrial translational machinery from oxidative damage

  Vicky Katopodi, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and Caspase 3/7 (1:300) [Cleaved Caspase-3 (Asp175) (5A1E) (Cell Signaling)] ...
• Structures of BIRC6-Client Complexes Provide Mechanism of Smac-Mediated Release of Caspases

  Moritz Hunkeler, Cyrus Y. Jin, Eric S. Fischer, bioRxiv - Molecular Biology 2022

  Quote: ... casp-7 (Cell Signaling, 9492S), HtrA2 (Cell Signaling ...
• IRE1 RNase controls CD95-mediated cell death

  D Pelizzari-Raymundo, et al., bioRxiv - Cell Biology 2022

  Quote: ... Caspase-7 (Cell signaling, 12827), Caspase-9 (Cell signaling ...
• Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14

  Zoey A. Miller, et al., bioRxiv - Cancer Biology 2023

  Quote: ... caspase-7 (Cell Signaling #9492), cyclin D1 (Cell Signaling #2978) ...
• Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia

  Justin L. Blaize, et al., bioRxiv - Biochemistry 2023

  Quote: ... Caspase-7 (12827; Cell Signaling), CHK1 pS345 (2348T ...
• ROSALIND protects the mitochondrial translational machinery from oxidative damage

  Vicky Katopodi, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and for Caspase 3/7 1:300 [Cleaved Caspase-3 (Asp175) (5A1E) (Cell Signaling)] ...
• Tumor suppressor Hypermethylated in Cancer 1 represses expression of cell cycle regulator E2F7 in human primary cells

  Lucie Lanikova, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-phospho-p53 (Ser 15) (rabbit polyclonal, #9284, Cell Signaling; 1:500), an anti-α-tubulin (mouse monoclonal ...
• WEE1 kinase inhibition triggers severe chromosome pulverization in aneuploid cells

  Maria M. Haykal, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-phospho-tyrosine 15 Cdk1 (Cell Signaling Technology; 9111; 1:1,000 dilution), anti-CDK1 phosphorylated substrates (Cell signaling ...
• Dynamics of p53 DNA binding sites contributes to functional selectivity of p53-driven gene expression

  Jessy Safieh, et al., bioRxiv - Biochemistry 2022

  Quote: ... The blots were subsequently incubated overnight at 4°C with primary antibodies against p53 (DO-7 mouse mAb, Cell Signaling, Cat # 48818) and β actin (13E5 rabbit mAb ...
• A chromatin phase transition protects mitotic chromosomes against microtubule perforation

  Maximilian W. G. Schneider, et al., bioRxiv - Cell Biology 2021

  Quote: ... Cyclin B1 was detected with a monoclonal rabbit antibody (Cell Signaling, 12231S, 7, 1:800) and visualized using a donkey anti-rabbit Alexa Fluor 488 secondary antibody (Molecular Probes ...
• ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion

  Demis Menolfi, et al., bioRxiv - Genetics 2023

  Quote: ... Primary antibodies used in the study are: ATR(1: 1000, Cell signaling #2790, Lot.7), pKAP1 S824 (1:1000 ...
• The RNA helicase DDX5 promotes alveolar rhabdomyosarcoma growth and survival

  Alberto Gualtieri, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cleaved caspase 7 (Cell signaling #8438), cleaved caspase 9 (Cell signaling #9505) ...
• Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism

  Akihiro Yamashita, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cleaved Caspase-7 (Cell Signaling, 9491), CRABP2 (Proteintech ...
• CD11B⁺CD36⁺ cells are bone anabolic macrophages that limit age-associated bone loss

  Jinsha Koroth, et al., bioRxiv - Cell Biology 2024

  Quote: ... TCF1/7 (Cell Signaling Technology, 2203T), phospho-JNK (Cell Signaling Technology ...
• Optical TrkB activation in Parvalbumin interneurons regulates intrinsic states to orchestrate cortical plasticity

  Frederike Winkel, et al., bioRxiv - Neuroscience 2020

  Quote: ... blocked in TBST with 3% BSA for 1 hour at room temperature and incubated in primary antibody solutions (in TBST with 3% BSA) directed against: phosphorylated (pY816, #4168, 1:1000; pY515, #9141, 1:1000; pY706-7, #4621S, 1:1000, Cell signaling technology (CST), Danvers ...
• Endothelial Caspase-9 Promotes Glial Changes, Inflammation, and Contrast Sensitivity Decline in Retinal Vascular Injury

  Crystal Colón Ortiz, et al., bioRxiv - Neuroscience 2022

  Quote: ... and AQP-4 (1:100 Cell Signaling 59678S) were prepared with blocking buffer and sections were incubated overnight at 4°C ...
• Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity

  Aparajitha Vaidyanathan, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Argonaute-4 (1:1000) (Cell Signaling #6913), anti-Dicer (1:1000 ...
• Autophagy-associated Production of Antimicrobial Peptides hBD1 and LL37 Exhibits Anti-Bacillus Calmette-Guérin Effects in Lung Epithelial Cells

  Rui-ning Wang, et al., bioRxiv - Immunology 2020

  Quote: ... anti-ATG 7 (8558; Cell Signaling Technology), anti-p62 (23214S ...
• DSS-induced inflammation in the colon drives a pro-inflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod

  Sarah Talley, et al., bioRxiv - Immunology 2021

  Quote: ... anti-caspase-7 (#9492, Cell Signaling Technology), anti-caspase-8 (#8592 ...
• Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia

  Justin L. Blaize, et al., bioRxiv - Biochemistry 2023

  Quote: ... Cleaved Caspase-7 (D198) (8438; Cell Signaling), Cleaved PARP (D214 ...
• Acetyl-CoA Carboxylase Obstructs CD8⁺ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

  Elizabeth G. Hunt, et al., bioRxiv - Immunology 2023

  Quote: ... TCF1/7-PE-Cy7 (Cell Signaling Technology), Granzyme B-Alexa Fluor 700 (Biolegend) ...
• Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control

  Brian P. Riesenberg, et al., bioRxiv - Immunology 2023

  Quote: ... TCF1/7-PE-Cy7 (Cell Signaling Technology), Granzyme B-Alexa Fluor 700 (Biolegend) ...
• Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor

  Patricia D.B. Tiburcio, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Caspase-7 (Cell Signaling Technology 12827, RRID:AB_2687912), cleaved Caspase-7 (Cell Signaling Technology 8438 ...
• mir-21 is associated with inactive low molecular weight Argonaute complexes in thyroid cancer cell lines

  Bonita H. Powell, et al., bioRxiv - Molecular Biology 2020

  Quote: ... PABP1 1:1000 dilution (Cell Signaling 4992 Lot#4), RPL26 1:1000 dilution (Bethyl A300-686A-M Lot#A300-686A-M-1) ...
• Dysregulation of NRSF/REST via EHMT1 is associated with psychiatric disorders

  Mouhamed Alsaqati, et al., bioRxiv - Neuroscience 2021

  Quote: ... Oct-4 (1:200, 2750, Cell Signaling Technology, USA), Sox2 (1:200 ...
• Transcriptomic landscape of human induced pluripotent stem cell-derived osteogenic differentiation identifies a regulatory role of KLF16

  Ying Ru, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-OCT-4 (Cell signaling technology, 2840S, 1/400), and anti-SOX2 (Abcam ...
• Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model

  Sarah M Bernhardt, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Ki67 (Cell Signaling, 1:400, overnight at 4°C), or Cleaved Caspase-3 (CC3 ...
• E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model

  Ibrahim M Sayed, et al., bioRxiv - Cancer Biology 2024

  Quote: ... overnight at 4°C (1:250, Cell Signaling, #9718). After subsequent washes in TBST ...
• Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration

  Marta Marzullo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... all diluted in TBS-T: anti-p-p53 (Ser 15; 1:1000, Santa Cell Signaling), anti-p53 (1:1000 ...
• Multivalent coiled-coil interactions enable full-scale centrosome assembly and strength

  Manolo U. Rios, et al., bioRxiv - Cell Biology 2023

  Quote: ... Primary Antibodies: Mouse anti-alpha tubulin (1:1,000; Cell Signaling Technologies, Product # 3873S Lot #15); Goat anti-enhanced GFP (1:5,000 ...
• AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans

  Brendan J. Houston, et al., bioRxiv - Cell Biology 2023

  Quote: ... and dual stained with the transcription factor marker FOXO1 (day 7; 1 µg/ml, Cell Signaling Technology 2880) and differentiating spermatogonia marker c-KIT (day 7 ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved Caspase-7 (Asp198) (Cell Signaling Technology, 9491), cell cycle regulation antibody sampler kit (Cell Signaling Technology ...
• TGF-β1 inhibits cholesterol metabolism in hepatocytes to facilitate cell death, EMT and signals for HSC activation

  Sai Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... Caspase 7 antibody (cat. #9492, Cell Signaling Technology); cleaved Caspase 7 antibody (cat ...
• The gold complex auranofin sensitizes platinum resistant epithelial ovarian cancer cells to cisplatin

  Farah H Abdalbari, et al., bioRxiv - Pathology 2024

  Quote: ... monoclonal caspase-7 antibody (D2Q3L1) (12827S, Cell Signaling, polyclonal cytochrome c antibody (4272 ...
• Nucleus translocation of tRNA synthetase mediates late integrated stress response

  Na Wei, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit monoclonal ATF-4 (1:1000, Cell Signaling Technology, #11815), rabbit polyclonal SARS (1:1000 ...
• Pachytene karyotypes of 17 species of birds

  Anastasia Y. Slobodchikova, et al., bioRxiv - Genetics 2022

  Quote: ... human anticentromere (1:100; Antibodies Inc., cat# 15-234) and mouse monoclonal anti-H3K9me2/3 (1:100, Cell Signaling, cat# 5327) primary antibodies ...
• Ehrlichia Notch signaling induction promotes XIAP stability and inhibits apoptosis

  LaNisha L. Patterson, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit monoclonal α-Caspase-7 (9494S; Cell Signaling Technology), rabbit monoclonal α-Caspase-8 (4790T ...
• TGF-β1 inhibits cholesterol metabolism in hepatocytes to facilitate cell death, EMT and signals for HSC activation

  Sai Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... cleaved Caspase 7 antibody (cat. #8438, Cell Signaling Technology); Phospho-Smad2 (Ser465/467 ...
• Activity-dependent LTP in the dentate gyrus promotes epileptic seizures

  Kaoutsar Nasrallah, et al., bioRxiv - Neuroscience 2021

  Quote: ... at 4°C (rabbit anti-c-Fos, 1:1000; Cell Signaling, cat # 2250S ...
• KAT6A mutations drive transcriptional dysregulation of cell cycle and Autism risk genes in an Arboleda-Tham Syndrome cerebral organoid model

  Aileen A. Nava, et al., bioRxiv - Genetics 2023

  Quote: ... and mouse anti-OCT3/4 (Cell Signaling #75463 at 1/1000). The following day ...