Labshake search

1 - 50 of 10000+ citations for 2 5 Sulfanyl 4H 1 2 4 triazol 3 yl phenol since 2020

• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-PAK1/2/3 (Cell Signaling 2604, 1:1000), rabbit anti-phospho-Cofilin (S3 ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PAK 1/2/3 1:1000 (Cell Signaling Technology Cat# 2604, RRID:AB_2160225), Myc-Tag 1:1000 (Cell Signaling Technology Cat# 2276 ...
• PAK1 and PAK2 in cell metabolism regulation

  Tereza Kořánová, et al., bioRxiv - Cell Biology 2021

  Quote: ... PAK1/2/3 (Cell Signaling, #2604), and β-actin (Sigma–Aldrich ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... PAK1/2/3 (Cell Signaling, # 2604S), pLIMK1/2 (Cell Signaling ...
• Loss of PRICKLE1 in the myometrium leads to reduced fertility, abnormal myometrial architecture, and aberrant extracellular matrix deposition in mice

  Emily R Roberts, et al., bioRxiv - Physiology 2024

  Quote: ... anti-RAC1/2/3 (Cell Signaling Technology, Cat# 2465P, 1:1000), anti-RHOA (Cell Signaling Technology ...
• Atheroprone Flow Activates SMAD-FOXO1 to drive Endothelial-to-Mesenchymal Transition and Atherosclerosis

  Paul-Lennard Mendez, et al., bioRxiv - Genomics 2024

  Quote: ... SMAD2/3 (SMAD 2/3 XP, Cell Signaling Technology 8685) or isotype control (Rabbit IgG XP ...
• Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton

  Wenqing Zhou, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Rac1/2/3 (Cell Signaling 2465S) and secondary antibodies anti-rabbit (ThermoFisher SA5-35571) ...
• Sterol O-acyltransferase (SOAT/ACAT) activity is required to form cholesterol crystals in hepatocyte lipid droplets

  Jordan A Bairos, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and incubated overnight at 4°C with primary antibody detecting light chain 3 type 1 and 2 (Cell Signaling technology, catalog #3868), SOAT1 (catalog #84476) ...
• Crystal structure of a novel guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi

  Christopher Lim, et al., bioRxiv - Microbiology 2020

  Quote: ... rabbit anti-Rac1/2/3 (2465, Cell Signaling), rabbit anti-Cdc42 (2466 ...
• SARS-CoV-2 spike protein induces brain pericyte immunoreactivity in absence of productive viral infection

  Rayan Khaddaj-Mallat, et al., bioRxiv - Neuroscience 2021

  Quote: Pericytes viability was assessed using the 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay according to the manufacturer’s procedure (Cell Signaling Technology). Cells were plated at the appropriate concentration in 96-well plates under different experimental conditions ...
• Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

  Hui Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... The membranes were blocked with 5% non-fat dry milk for 2 h at RT and incubated overnight at 4°C with rabbit anti-phospho-ERK1/2 (1:2000, Cell Signaling), anti-phospho-Ser473-Akt (1:2000 ...
• SUMO Modifies GβL and Mediates mTOR Signaling

  Sophia Louise Lucille Park, et al., bioRxiv - Biochemistry 2020

  Quote: ... SUMO-1 (4930) and SUMO-2/3 (4971) were obtained from Cell Signaling Technology. 6x-His tag Antibody (MA1-125 21315 ...
• Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

  Hussam Husanie, et al., bioRxiv - Cancer Biology 2022

  Quote: ... monoclonal pSMAD 2/3 (Cell Signaling; 8828, Massachusetts, USA), monoclonal pSMAD 1/5/9 (Cell Signaling ...
• Proteomic analysis reveals complex interactions between PERK/ISR and MAPK1 in translational control in a phenotypic toxin model of Parkinson’s disease expressing PINTAC peptides

  Girish N Nallur, bioRxiv - Systems Biology 2024

  Quote: ... RSK1/2/3 (Cat. No. 9355; Cell Signaling Technology), pRPS6 (Cat ...
• Constitutive signal bias mediated by the human GHRHR splice variant 1

  Zhaotong Cong, et al., bioRxiv - Molecular Biology 2021

  Quote: ... The membranes were blocked with 5% BSA in TBST buffer for 2 h at RT and incubated overnight at 4°C with primary antibodies against ERK1/2 (1:1000; 9102s, Cell Signaling Technology), pERK1/2 (1:1000 ...
• Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration

  Jorge L. Cueva-Vargas, et al., bioRxiv - Neuroscience 2024

  Quote: ... Mitofusin-2 (MFN-2, 1 μg/ml, Cell Signaling Technology), Optic protein atrophy-1 (OPA1 ...
• Methods for detection of cardiac glycogen-autophagy

  Parisa Koutsifeli, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Antibodies were sourced for GABARAPL1 (#1: Proteintech, #11010-1-AP; #2 Abcam, #ab86497; #3: Cell Signaling, #26632), LC3B (Cell Signaling #2775) ...
• Thrombospondin 2 is a key determinant of fibrogenesis in NAFLD

  Takefumi Kimura, et al., bioRxiv - Molecular Biology 2023

  Quote: ... small mothers against decapentaplegic (SMAD) 2/3 (D7/G7) (Cell Signaling Technology, #8685, 1:1,000), Phospho-Smad2 (Ser465/467)/Smad3 (Ser423/425 ...
• Developmental molecular controls over arealization of descending cortical motor pathways

  Philipp Abe, et al., bioRxiv - Neuroscience 2023

  Quote: ... and subsequently incubated for 2 days with cleaved caspase 3 (1:200, Cell signaling 9661, LOT38) primary antibody at 4 °C ...
• Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

  Avital Licht-Murava, et al., bioRxiv - Neuroscience 2022

  Quote: ... ERK1/2 (1:1000 mouse anti-total ERK1/2; Cell Signaling Technology #4696 ...
• Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

  Jill E. Hunter, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK 1/2 (9102 Cell Signaling), AKT (phospho S473 ...
• 17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

  Samim Ali Mondal, et al., bioRxiv - Physiology 2022

  Quote: ... MMP-2 (Cell Signaling; 1:1000), TIMP-1 (Sino Biological ...
• Lipid Dysregulation Unveil the Intricate Interplay of Lysosomal and Mitochondrial Changes in Frontotemporal Dementia with GRN Haploinsufficiency

  Jon Ondaro, et al., bioRxiv - Neuroscience 2024

  Quote: ... LAMP-2 (1:1 000, #49067, Cell Signaling), LC3Bxp (1:1 000 ...
• Differential LRRK2 signalling and gene expression in WT-LRRK2 and G2019S-LRRK2 mouse microglia treated with zymosan and MLi2

  Iqra Nazish, et al., bioRxiv - Neuroscience 2023

  Quote: ... and anti-4′,6-diamidino-2-phenylindole (DAPI) (Cell Signaling #4083). The primary microglial yield was approximately 5 × 105 cells/flask with minimal astrocyte contamination ...
• Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

  Ferrol I. Rome, et al., bioRxiv - Physiology 2022

  Quote: ... and 3-hydroxymethylglutaryl-CoA synthase 2 (HMGCS2; Cell Signaling Technology, 20940S; RRID:AB_2798853). All primary antibodies were used as a dilution of 1:1000 ...
• Optimized transcriptional signature for evaluation of MEK/ERK pathway baseline activity and long-term modulations in ovarian cancer

  Mikhail S. Chesnokov, Anil Yadav, Ilana Chefetz, bioRxiv - Cancer Biology 2022

  Quote: ... and probed overnight at 4°C with the following primary antibodies diluted in 5% BSA in TBST: pMEK1/2 (Cell Signaling Technology, Danvers, MA, USA, 41G9, 1:1000), pERK1/2 (Cell Signaling Technology ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (#4695S, 1:1000, Cell Signaling), p-STAT3 Y705 (#4370S ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... pERK1/2 1:50 (Cell Signaling 4377s), SOX2 1:100 (R&D AF2018) ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... MEK1/2 1:1000 (Cell Signaling 8727s), and GAPDH 1:10,000 (Sicgen AB0049-20 ...
• Injury-induced Erk1/2 signaling enhances Ca²⁺ activity and is necessary for regeneration of spinal cord and skeletal muscle

  Jacqueline B. Levin, Laura N. Borodinsky, bioRxiv - Neuroscience 2021

  Quote: ... pERK1/2 1:50 (Cell Signaling 4377s), and Xen1 1:100 (deposited to Developmental Studies Hybridoma Bank (DSHB ...
• DOK1 and DOK2 regulate CD8⁺ T cell signaling and memory formation without affecting tumor cell killing

  V. Laletin, et al., bioRxiv - Immunology 2021

  Quote: ... Erk-1/2 (Cell Signaling Technology #9102) and β-Actin (Cell Signaling Technology #3700) ...
• Extracellular Vesicle-Mediated Purinergic Signaling Contributes to Host Microenvironment Plasticity and Metastasis in Triple Negative Breast Cancer

  Suzann Duan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... COX-2 (1:50, Cell Signaling Technologies), and GAPDH (Cell Signaling Technologies ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Erk1/2 (1:1000; L34F12; Cell Signaling), phospho(Ser473)-AKT (1:2000 ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MEK1/2 (1:1000; L38C12; Cell Signaling), phospho(Thr44/Tyr42)-ERK1/2 (1:1000 ...
• STAT3 but not STAT5 contributes to the protective effect of electro-acupuncture against myocardial ischemia/reperfusion injury

  Hui-Hui Guo, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Bcl-2 (1:1000, Cell Signaling, #3498), Cyt c (1:1000 ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... ERK1/2 (Cell Signaling, 9102, 1:2,000), p-ERK1/2 (T202/Y204 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MEK1/2 (1:500 Cell Signaling Technology), phospho-ERK1/2 (Thr202/Tyr204 ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MEK1/2 (Cell Signaling, 9122, 1:1000), total H3 (Abcam ...
• Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

  Hui Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-ERK1/2 (1:2000, Cell Signaling), and anti-AKT (1:2000 ...
• Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue

  Megan Moruzzi, et al., bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 1:1000 (Cell Signaling, #9102S), α-tubulin (Sigma Aldrich ...
• Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR

  Alice Laschuk Herlinger, et al., bioRxiv - Cancer Biology 2023

  Quote: ... pERK1/2 (1:1,000; Cell Signaling, #9101), ERK1/2 (1:1,000 ...
• Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR

  Alice Laschuk Herlinger, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (1:1,000; Cell Signaling, #4695), pAKT (Thr308 ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pERK1/2 (1:1000, Cell Signaling), anti-MBP (1:1000 ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pERK1/2 (1:500, Cell Signaling), anti-pERK1/2 (1:1000 ...
• The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer’s disease

  Felipe C. Ribeiro, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERK1/2 (#9102, 1:1,000; Cell Signaling); phospho-p70S6K1 Thr389 (#9205 ...
• CRIPTO promotes extracellular vesicle uptake and activation of cancer associated fibroblasts

  David W. Freeman, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ERK1/2 (L34F12, Cell Signaling, 1:2000), Vinculin (Clone EPR8185 ...
• Epithelial IL-2 is critical for NK cell-mediated cancer immunosurveillance in mammary glands

  Lei Wang, et al., bioRxiv - Immunology 2024

  Quote: ... ERK1/2 (4695S, Cell Signaling, 1: 1000), phospho-ERK1/2 (4370S ...
• Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome

  Rosalba Olga Proce, et al., bioRxiv - Neuroscience 2024

  Quote: ... ERK1/2 (Cell Signaling, #4695, 1:500), MNK1 (Cell Signaling ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... MEK1/2 (Cell Signaling 1:1000, #9122, 1:1000), phospho-MEK1/2 S217/221 (Cell Signaling ...
• Preserving endothelial integrity in human saphenous veins during preparation for coronary bypass surgery

  Meghan W. Sedovy, et al., bioRxiv - Physiology 2023

  Quote: ... and nuclear factor erythroid 2-related factor 2 (NRF2, #12721, 1:25, Cell Signaling Technology). Antibody binding was identified by incubation with goat anti-rabbit or anti-mouse secondary antibodies (Thermo Fisher Scientific ...