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4851 - 4900 of 10000+ citations for 7 Methyl 1 5 dioxo 1 2 3 5 tetrahydro indolizine 6 carbonitrile since 2019

• Self-organized stem cell-derived human lung buds with proximo-distal patterning and novel targets of SARS-CoV-2

  E.A. Rosado-Olivieri, et al., bioRxiv - Developmental Biology 2021

  Quote: ... phospho Histone H3 (Cell Signaling; 9706S; 1:200) and goat anti-SOX17 (R&D Systems ...
• BAP1/ASXL complex modulation regulates Epithelial-Mesenchymal Transition during trophoblast differentiation and invasion

  Vicente Perez-Garcia, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-BAP1 1:200 (Cell Signaling, D1W9B #13187), anti-ESRRB 1:200 (R&D Systems H6707) ...
• Allosteric interactions prime androgen receptor dimerization and activation

  Elizabeth V. Wasmuth, et al., bioRxiv - Biochemistry 2022

  Quote: ... and Cyclophilin B (Cell Signaling 43603S - 1:5000).
• A conditional null allele of Dync1h1 enables targeted analyses of dynein roles in neuronal length sensing and neurological disorders

  Agostina Di Pizio, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-mTOR (Cell Signaling, #2972, 1:1000), rabbit anti-Nucleolin (Abcam ...
• Dynamic plasticity within the EMT spectrum, rather than static mesenchymal traits, drives tumor heterogeneity and metastatic progression of breast cancers

  Meredith S. Brown, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Vimentin (Cell Signaling Technology; CST #5741, 1:2000), RUNX1 (CST #4336 ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-MCM7 (Cell Signaling, 3757S; 1:1000), mouse anti-GAPDH (GeneTex ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-MCM4 (Cell Signaling, 3228S; 1:1000); rabbit anti-MCM7 (Cell Signaling ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-MCM3 (Cell Signaling, 4012S; 1:1000), rabbit anti-MCM4 (Cell Signaling ...
• Signaling from the RNA sensor RIG-I is regulated by ufmylation

  Daltry L. Snider, et al., bioRxiv - Immunology 2022

  Quote: ... R-anti-IRF3 (Cell Signaling Technology, 1:1000), R-anti-UFL1 (Novus Biologicals ...
• Signaling from the RNA sensor RIG-I is regulated by ufmylation

  Daltry L. Snider, et al., bioRxiv - Immunology 2022

  Quote: ... R-anti-GAPDH (Cell Signaling Technology, 1:1000), R-anti-p-IRF3 (Cell Signaling Technology ...
• Kidney failure alters parathyroid Pin1 phosphorylation and parathyroid hormone mRNA binding proteins leading to secondary hyperparathyroidism

  Alia Hasan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... total Pin1 (1:500 Cell Signaling, Beverly, MA), PTH (1:1000 ...
• Oligomeric amyloid beta prevents myelination in a clusterin-dependent manner

  Rebecca M. Beiter, et al., bioRxiv - Neuroscience 2022

  Quote: ... and Aβ (1:300, Cell Signaling Technology, 8243S). Secondary antibodies used were Donkey anti-Goat Cy3 (2μg/mL ...
• Dopamine ameliorates hyperglycemic memory-induced vascular dysfunction in diabetic retinopathy

  Yeon-Ju Lee, et al., bioRxiv - Biochemistry 2022

  Quote: ... or β-actin (1:2000, Cell Signaling Technology), followed by incubation with a horseradish peroxidase-conjugated secondary antibody ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Akt (Cell Signaling, #4691, 1:1000); rabbit anti- Drosophila phospho-Akt Ser505 (Cell Signaling ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... p-S6K1 (1:1000; Ser389) (Cell Signaling, Cat#), S6K1 (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... p-ULK1 (1:1000; Ser317) (Cell Signaling, Cat#), ULK1 (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... p-eEF2 (1:1000; Thr56) (Cell Signaling, Cat#), eEF2 (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... p-mTOR (1:1000; Ser2448) (Cell Signaling, Cat#), mTOR (1:1000 ...
• The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition

  Pablo Tristán-Ramos, et al., bioRxiv - Molecular Biology 2020

  Quote: ... or anti mouse HRP (1:1000, Cell Signaling), and Clarity ECL Western Blotting Substrate (BioRad ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... LC3A/B (Cell Signaling Technologies; 12741; 1:1000); SQSTM1/p62 (Cell Signaling Technologies ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... SQSTM1/p62 (Cell Signaling Technologies; 5114; 1:1000), GAPDH (Cell Signaling Technologies ...
• Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2

  Polina Kosillo, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-DARPP32 (1:1500, Cell Signaling: 2306S); mouse anti-Histone- 3 (1:1500 ...
• Nanometer-Scale Imaging of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels

  Hui Liu, et al., bioRxiv - Neuroscience 2021

  Quote: ... HA tag (3724, Cell Signaling Technology, 1:1000), AnkG (75-146 ...
• Transcriptional regulation of ACSL1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation

  Prashanth Thevkar-Nagesh, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit anti-histone H3 (1:1,000; Cell Signaling), rabbit anti-actin (1:5,000 ...
• Big fish, little fish: N-terminal acetyltransferase Naa40p proteoforms caught in the act

  Veronique Jonckheere, Petra Van Damme, bioRxiv - Molecular Biology 2021

  Quote: ... rabbit anti-PRKACA (Cell Signaling, #5842S, 1/2000), rabbit anti-c-Src (Cell Signaling ...
• Diet-dependent Natriuretic Peptide Receptor C expression in adipose tissue is mediated by PPARγ via long-range distal enhancers

  Fubiao Shi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-ADIPOQ (1:1000, Cell Signaling Technology, #2789), anti-GAPDH (1:2000 ...
• Diet-dependent Natriuretic Peptide Receptor C expression in adipose tissue is mediated by PPARγ via long-range distal enhancers

  Fubiao Shi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-PPARγ (1:2000, Cell Signaling Technology, #2435), anti-FABP4 (1:1000 ...
• Diet-dependent Natriuretic Peptide Receptor C expression in adipose tissue is mediated by PPARγ via long-range distal enhancers

  Fubiao Shi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-FABP4 (1:1000, Cell Signaling Technology, #2120), anti-ADIPOQ (1:1000 ...
• Human Polyomavirus-Encoded Circular RNAs

  Rong Yang, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-Calnexin (1:1000, Cell Signaling Technologies, 2679T), anti-β-Tublin (1:1000 ...
• Human Polyomavirus-Encoded Circular RNAs

  Rong Yang, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-HSP90 (1:1000, Cell Signaling Technologies, 4877S), anti-CD63 (1:600 ...
• Myotube hypertrophy is associated with cancer-like metabolic reprogramming and limited by PHGDH

  Lian E.M. Stadhouders, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Phospho-AMPK (Thr172, 1:500, Cell Signaling Technology, Cat# 2531 ...
• Myotube hypertrophy is associated with cancer-like metabolic reprogramming and limited by PHGDH

  Lian E.M. Stadhouders, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Phospho-AKT Ser473 (1:2000; Cell Signaling Technology, Cat# 4060 ...
• RNA-protein interaction mapping via MS2 or Cas13-based APEX targeting

  Shuo Han, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit anti-HA (Cell Signaling, 1:1000 dilution), FLAG-PE (Miltenyi Biotec ...
• Lipid nanoparticles delivering constitutively active STING mRNA as a novel anti-cancer therapeutic approach

  Wei Liu, et al., bioRxiv - Bioengineering 2022

  Quote: ... anti-cGAS (1:1000, 15102, Cell Signaling Technology), and anti-GAPDH (1:2000 ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/500 E-Cadherin (Cell Signaling Technologies, 3195); 1/100 G3BP (BD Bioscience 611126) ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/1000 p62/SQSTM1 (Cell Signaling Technologies, 5114); 1/1000 Atf4 (Cell Signaling Technologies ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/1000 β-Actin (Cell Signaling Technologies, 3700); 1/1000 p-eIF2α (Invitrogen ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/5000 p-eIF2α (Cell Signaling Technologies, 3597); 1/1000 eif2a (Cell Signaling Technologies ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/250 p62/SQSTM (Cell Signaling Technologies, 7695); 1/500 LaminB1 (Santa Cruz ...
• FAM21 is critical for TLR2-CLEC4E-mediated dendritic cell function against Candida albicans

  Rakesh Kulkarni, et al., bioRxiv - Cell Biology 2022

  Quote: ... or anti-SYK (Cell Signaling Technologies, 1:1000) antibodies ...
• MUCOSECRETORY LUNG DISEASE: DIFFERENT ASSEMBLIES OF JAG1 AND JAG2 DETERMINE TRACHEOBRONCHIAL CELL FATE

  Susan D. Reynolds, et al., bioRxiv - Cell Biology 2022

  Quote: ... JAG2-C-terminal (Cell Signaling C83A8, 1:1000); GSK3 (Millipore 05-412 ...
• Profilin 1 deficiency drives mitotic defects and impairs genome stability

  Federica Scotto di Carlo, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-p53 (Cell Signaling, 2524, 1:2’000); mouse anti-α-Tubulin (Sigma ...
• Profilin 1 deficiency drives mitotic defects and impairs genome stability

  Federica Scotto di Carlo, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-p53 (Cell Signaling, 2524, 1:1’000); mouse anti-α- Tubulin (Sigma ...
• Prom1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium

  Carlos F. H. Serra, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-p63-α (Cell Signaling #13109, 1:100), anti-RBPSUH (Cell Signaling #5313 ...
• RNA promotes the formation of spatial compartments in the nucleus

  Sofia A. Quinodoz, et al., bioRxiv - Genomics 2020

  Quote: ... anti-CENP-A (Cell Signaling C51A7, 1:500); anti-HP1beta (Active Motif 39979 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-p62 phS349 (1:100, Cell Signaling).
• BCL6-dependent TCF-1⁺ progenitor cells maintain effector and helper CD4 T cell responses to persistent antigen

  Yu Xia, et al., bioRxiv - Immunology 2021

  Quote: ... Unconjugated anti-TCF-1 (Cell Signaling Technology, C63D9).
• Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase

  Xuan Mo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... pStat1 (Y701, 58D6, 1:1000, Cell Signaling Technology), Stat3 (124H6 ...
• Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase

  Xuan Mo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... pStat3 (Y705, D3A7, 1:2000, Cell Signaling Technology), Irf1 (D5E4 ...
• CDK5 influences the organization of the Circadian Machinery in peripheral clocks

  Jürgen Ripperger, Urs Albrecht, Andrea Brenna, bioRxiv - Molecular Biology 2021

  Quote: ... CDK5 purchased by Cell Signaling Tech (1:1000), while Tubulin by Abcam (1:1000 ...