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4701 - 4750 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• CRIPTO promotes extracellular vesicle uptake and activation of cancer associated fibroblasts

  David W. Freeman, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Calnexin (Clone C5C9, Cell Signaling, 1:1000), HSP70 (#4872 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... NT5E (1:1000; Cell Signaling Technology, #13160), HPRT1 (1:1000 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... AKT (1:1000; Cell Signaling Technology, #4685), P-AKT(Ser473 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... RICTOR (1:1000; Cell Signaling Technology, #5379), P-RICTOR (1:1000 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... A20 (1:1000; Cell Signaling Technology, #5630), RICTOR (1:500 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... ERK (1:1000; Cell Signaling Technology, #9102), P-ERK (1:1000 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... IKKβ (1:1000; Cell Signaling Technology, #2370), P-IKKα/β (Ser176/180 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... RELA (1:1000; Cell Signaling Technology, #8242), A20 (1:1000 ...
• Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

  Hélène Lasolle, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and β-Actin (1:1,1000; Cell Signaling) in a blocking solution ...
• Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence

  Tung D. Nguyen, et al., bioRxiv - Physiology 2023

  Quote: ... anti-FoxO1 (1:1000, Cell Signaling, 2880S); anti-LaminA/C (1:1000 ...
• Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging

  Vanitha Nithianandam, et al., bioRxiv - Neuroscience 2023

  Quote: ... pSMAD1/5/9 (1:2000, Cell Signaling), GABARAP (1:2000 ...
• Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover

  Michael J. Podolsky, et al., bioRxiv - Cell Biology 2023

  Quote: ... MYC (1:5,000; Cell Signaling Technology, 9B11), OS9 (1:2,000 ...
• Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover

  Michael J. Podolsky, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (1:4,000; Cell Signaling Technology, 14C10), or beta-Actin (1:10,000 ...
• Niche homeostasis in multi-lineage stem cell populations is maintained through intercellular redox gradients

  Olivia Majhi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-pERK (1:100, Cell Signaling (4370)) ...
• Adaptive epigenetic regulation of neuronal metabolism by a mitochondrial redox signal

  Marius W. Baeken, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-DNMT3A (2160, Cell Signaling, 1:100), anti-DNMT3B (67259 ...
• Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA

  Claire D. James, et al., bioRxiv - Cancer Biology 2023

  Quote: ... MRE11 1/500 (Cell Signaling Technology, 4847), V5-Tag 1/1000 (Life Technologies ...
• Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA

  Claire D. James, et al., bioRxiv - Cancer Biology 2023

  Quote: ... SAMHD1 1/1000 (Cell Signaling Technology, 49158), phospho-SAMHD1 1/500 (Cell Signaling Technology ...
• ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle

  Antentor Hinton Jr., et al., bioRxiv - Biophysics 2023

  Quote: ... VDAC (1:1000; Cell Signaling Technology; #4866), SERCA (1:1000 ...
• Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension

  Brandon Elliott, et al., bioRxiv - Physiology 2024

  Quote: ... p-CREB (Ser133; 1:1,000; Cell signaling), CREB (1:1,000 ...
• Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

  Heidi H. Pak, et al., bioRxiv - Physiology 2024

  Quote: ... S6K (1:1,000; Cell Signaling Technology #2708S), p-S757-ULK (1:500 ...
• Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

  Heidi H. Pak, et al., bioRxiv - Physiology 2024

  Quote: ... AKT (1:1,000; Cell Signaling Technology #4691), p-p70 S6K1 (1:500 ...
• Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

  Heidi H. Pak, et al., bioRxiv - Physiology 2024

  Quote: ... ULK (1:500; Cell Signaling Technology #8054S), p-AMPK (1:1,000 ...
• B4 Raf-like MAPKKK RAF24 regulates Arabidopsis thaliana flowering time through HISTONE MONO-UBIQUITINATION 2

  Qiaomu Li, et al., bioRxiv - Plant Biology 2024

  Quote: ... anti-H2Bub1 (1:1000, Cell Signaling, #5546), anti-GFP (1:2000 ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... SAPK/JNK (#9252, Cell signaling, 1:1000), Phospho-Akt (Thr308 ...
• Intrinsic skeletal muscle function and contraction-stimulated glucose uptake do not vary by time-of-day in mice

  Liam S. Fitzgerald, et al., bioRxiv - Physiology 2024

  Quote: ... 1 mM trichostatin A (Cell Signaling #9950S), Complete (MilliporeSigma #11836170001) ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... p38 MAPK (#9212, Cell signaling, 1:1000), Phospho-SAPK/JNK (Thr183/Tyr185 ...
• Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity

  Irene Schwartz, et al., bioRxiv - Cell Biology 2024

  Quote: ... LC3B Antibody ((Cell Signaling Technology, 1:1000), Ubiquitin (P4D1 ...
• Endosomal actin branching, fission and receptor recycling require FCHSD2 recruitment by MICAL-L1

  Devin Frisby, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-EEA1 (3288, Cell Signaling, 1:30), anti-cortactin (05-180-I ...
• Inhibition of Inflammatory Osteoclasts Enhances CGRP⁺TrkA⁺ Signaling and Accelerates Callus Remodeling in Osteoporotic Fractures

  Yuexia Shu, et al., bioRxiv - Pathology 2024

  Quote: ... GAPDH (1:500, 8884, Cell Signaling Technology).
• Inhibition of Inflammatory Osteoclasts Enhances CGRP⁺TrkA⁺ Signaling and Accelerates Callus Remodeling in Osteoporotic Fractures

  Yuexia Shu, et al., bioRxiv - Pathology 2024

  Quote: ... TrkA (1:500, 2510, Cell Signaling Technology), p-TrkA (1:500 ...
• Oncogenic signaling in the adult Drosophila prostate-like accessory gland leads to activation of a conserved pro-tumorigenic program, in the absence of proliferation

  S. Jaimian Church, et al., bioRxiv - Developmental Biology 2024

  Quote: ... DP-MAPK 1:500 (Cell Signaling 4370s), Fas III 1:500 (DSBH 7G10) ...
• Oncogenic signaling in the adult Drosophila prostate-like accessory gland leads to activation of a conserved pro-tumorigenic program, in the absence of proliferation

  S. Jaimian Church, et al., bioRxiv - Developmental Biology 2024

  Quote: ... P-Akt 1:200 (Cell Signaling 4054s), P-4E-BP 1:200 (Cell Signaling 2855S) ...
• Heterochromatin protein ERH represses alternative cell fates during early mammalian differentiation

  Andrew Katznelson, et al., bioRxiv - Developmental Biology 2024

  Quote: ... anti-SOX2 (1:200, Cell Signaling, 23064), anti-OCT4 (1:200 ...
• pTDP-43 levels correlate with cell type specific molecular alterations in the prefrontal cortex of C9orf72 ALS/FTD patients

  Hsiao-Lin V. Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... and GAPDH (Cell Signaling, 2118, 1:3000) were used ...
• pTDP-43 levels correlate with cell type specific molecular alterations in the prefrontal cortex of C9orf72 ALS/FTD patients

  Hsiao-Lin V. Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... and TCF7L2 (Cell Signaling, 2569, 1:1000) were used ...
• Recovery after human bone marrow mesenchymal stem cells (hBM-MSCs)-derived extracellular vesicles (EVs) treatment in post-MCAO rats requires handling associated with repeated behavioral testing

  Yolanda Gomez-Galvez, et al., bioRxiv - Neuroscience 2024

  Quote: ... ALIX (1:1,000, mouse, Cell Signaling, #2171), CD9 (1:1,000 ...
• Cntnap2 loss drives striatal neuron hyperexcitability and behavioral inflexibility

  Katherine R. Cording, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-GAPDH (1:5000, Cell Signaling, #51745S), and anti-rabbit goat HRP conjugate (1:5000 ...
• Neuronal hypofunction and network dysfunction in a mouse model at an early stage of tauopathy

  Changyi Ji, et al., bioRxiv - Neuroscience 2024

  Quote: ... NeuN (1:200, Cell Signaling Technologies, D4G4O), GFAP (1:200 ...
• SNX10 regulates the clearance of mitochondrial proteins and mitochondrial bioenergetics

  Laura Trachsel-Moncho, et al., bioRxiv - Cell Biology 2024

  Quote: ... PDH (Cell Signaling Technology, #2784S, 1:1000), LC3B (Cell Signaling Technology ...
• SNX10 regulates the clearance of mitochondrial proteins and mitochondrial bioenergetics

  Laura Trachsel-Moncho, et al., bioRxiv - Cell Biology 2024

  Quote: ... LC3B (Cell Signaling Technology, #3868, 1:1000), SNX10 (Atlas Antibodies ...
• Mechanism of TAX1BP1 recruitment in aggrephagy to switch from cargo collection to sequestration

  Bernd Bauer, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti pTBK1-S172 (1:100, Cell Signaling), goat anti rabbit Alexa Fluor 546 (1:1000 ...
• Mechanism of TAX1BP1 recruitment in aggrephagy to switch from cargo collection to sequestration

  Bernd Bauer, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti TAX1BP1 (Cell Signaling, 1:1000). Secondary antibodies ...
• Mechanism of TAX1BP1 recruitment in aggrephagy to switch from cargo collection to sequestration

  Bernd Bauer, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti TAX1BP1 (1:100, Cell Signaling), anti pTBK1-S172 (1:100 ...
• Mechanism of TAX1BP1 recruitment in aggrephagy to switch from cargo collection to sequestration

  Bernd Bauer, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti FIP200 (1:200, Cell Signaling), mouse anti p62 (1:100 ...
• Stepwise developmental mimicry generates proximal-biased kidney organoids

  Jack Schnell, et al., bioRxiv - Developmental Biology 2024

  Quote: ... SIX1 (Cell Signaling Technology, 12891S, 1:300), HES1 (Cell Signaling Technology ...
• Stepwise developmental mimicry generates proximal-biased kidney organoids

  Jack Schnell, et al., bioRxiv - Developmental Biology 2024

  Quote: ... HES1 (Cell Signaling Technology, 11988, 1:300), POU3F3 (Novus Biologicals ...
• Endothelial Zmiz1 modulates physiological and pathophysiological angiogenesis during retinal development

  Nehal R Patel, et al., bioRxiv - Developmental Biology 2024

  Quote: ... CL-CASPASE3 (1:100, Cell signaling, 9661), ESM-1 (1:100 ...
• THE DUAL-SPECIFICITY KINASE DYRK1A INTERACTS WITH THE HEPATITIS B VIRUS GENOME AND REGULATES THE PRODUCTION OF VIRAL RNA

  Florentin Pastor, et al., bioRxiv - Microbiology 2024

  Quote: ... cyclin D1 (Cell Signaling 55506, 1:2000), HA (Abcam 130275 ...
• Porphyromonas gingivalis activates Heat-Shock-Protein 27 to drive a LC3C-specific probacterial form of select autophagy that is redox sensitive for intracellular bacterial survival in human gingival mucosa

  Bridgette Wellslager, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-Beclin 1 rabbit (Cell Signaling Technology, 3495 ...
• Identification of MYC synthetic lethal genes and networks

  Timothy D. Martin, et al., bioRxiv - Cancer Biology 2024

  Quote: ... β-actin(1:10,000, Cell Signaling, cat. # 3700), and GAPDH (1:10,000 ...