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4601 - 4650 of 10000+ citations for IL 1 Alpha Human since 2019

• Tissue-specific vulnerability to apoptosis in Machado-Joseph disease

  Ana F. Ferreira, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-p53 (1:1000; #2524, Cell Signaling), mouse anti-GAPDH (1:10000 ...
• SRC family kinase inhibition rescues molecular and behavioral phenotypes, but not protein interaction network dynamics, in a mouse model of Fragile X syndrome

  Vera Stamenkovic, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Fyn (1:1000, Cell Signaling, 4023), rabbit anti-alpha FMR1 (c-terminal ...
• FMRP-Regulated Alternative Splicing is Multifactorial and Resembles Splicing Control by MBNL1

  Suna Jung, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-MBNL2 (Cell signaling technology, 93182, 1:1000), anti-PTBP1 (Cell signaling technology ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-ATG7 (1:1000, #8558, Cell Signaling Technology), anti-ATG16L1 (1:1000 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-ATG16L1 (1:1000, #8089, Cell Signaling Technology), anti-FIP200 (1:1000 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-LC3B (1:1000, #2775, Cell Signaling Technology), anti-ATG7 (1:1000 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-vimentin (1:1000, #5741, Cell Signaling Technology), anti-β-tubulin (1:1000 ...
• Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma

  Priyanka Gupta, et al., bioRxiv - Cancer Biology 2023

  Quote: ... GFP (Cell Signaling Technology 2956; RRID:AB_1196615; 1:2000), P-T202 LARP6 (Bibb Lab ...
• BMP7 promotes cardiomyocyte regeneration

  Chiara Bongiovanni, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti- phospho-AKT (1:1000, 9271, Cell Signaling), anti-GAPDH (1:1000 ...
• NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

  Ken Takashima, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Geminin (#52508, Cell Signaling Technology, 1:1000), anti-Thymidine Kinase 1(TK1 ...
• Chemotherapeutic regulation of the ROS/MondoA-dependent TXNIP/GDF15 axis; and derivation of a new organoid metric as a predictive biomarker

  Jinhai Deng, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and Lamin A (1:1000, Cell Signaling Technology) were used for incubation overnight at 4 °C.
• NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

  Ken Takashima, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-HSP90 (#4874, Cell Signaling Technology, 1:1000), anti-Geminin (#52508 ...
• Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

  Evangelia Chavdoula, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ATF4 1:100 (Cell Signaling Technology, Cat 11815), c-MYC 1:100 (Cell Signaling Technology ...
• Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

  Evangelia Chavdoula, et al., bioRxiv - Cancer Biology 2023

  Quote: ... H2AK119ub 1:100 (Cell Signaling Technology, Cat 8240), H3K27ac (Cell Signaling Technology ...
• Late-life Rapamycin Treatment Enhances Cardiomyocyte Relaxation Kinetics and Reduces Myocardial Stiffness

  Akash D. Chakraborty, et al., bioRxiv - Physiology 2023

  Quote: ... TnI-pS23/24 (1:1000, Cell signaling technology), Total TnI (1:1000 ...
• Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

  Lampros Mavrommatis, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-M-Cadherin (Cell Signaling Technology, 1:200) anti-SOX2 (ThermoFisher Scientific ...
• Lineage-specific intolerance to oncogenic drivers restricts histological transformation

  Eric E. Gardner, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti- EGFRL858R-PE (Cell Signaling #64716; 1:500), anti-EpCam-A488 (Abcam # ab237384 ...
• Immortalization and transformation of primary cells mediated by engineered ecDNAs

  Davide Pradella, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-c-MYC (1:1,000; Cell SIgnaling, #D84C12), anti-MDM2 (1:1000 ...
• Weak neuronal glycolysis sustains cognition and organismal fitness

  Daniel Jimenez-Blasco, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-acetylated Lysine (1/1,000) (#9441; Cell Signaling), anti-Beclin (1/1,000 ...
• Regulation of Oocyte Meiotic Maturation: Unraveling the Interplay between PKA Inhibition and Cdk1 Activation

  Martina Santoni, et al., bioRxiv - Cell Biology 2023

  Quote: ... pY15-Cdk1 (1:1000, rabbit, Cell Signaling 9111), Cdk1 (1:5000 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-FIP200 (1:1000, #12436, Cell Signaling Technology), anti-ATG9A (1:1000 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-EGFR (1:100, #4267, Cell Signaling Technology), anti-GFP (1:500 ...
• GTPase activating protein DLC1 spatio-temporally regulates Rho signaling

  Max Heydasch, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1:50 for pMLC (Cell Signaling Antibody #3671). Secondary antibody incubation (1:1000 ...
• An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation

  Kai He, et al., bioRxiv - Cell Biology 2023

  Quote: ... Flag (8146, Cell Signaling Technology, dilution 1:2000), RAB11A (71-5300 ...
• An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation

  Kai He, et al., bioRxiv - Cell Biology 2023

  Quote: ... CDK7 (2916, Cell Signaling Technology, dilution 1:1000). E-Cadherin (24E10 ...
• Primate-expressed EPIREGULIN promotes basal progenitor proliferation in the developing neocortex

  Paula Cubillos, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 μL of anti-H3K27me3 (Cell Signaling, 9733) was used ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... pS6 (Cell Signaling; catalog no. 2211; 1:1000), S6 (Cell Signaling ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... CREB (Cell Signaling; catalog no. 9197; 1:1000), pCREB(Ser133 ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... pERK (Cell Signaling; catalog no. 4370; 1:1000), ERK (Cell Signaling ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... KLF4 (Cell Signaling; catalog no. 12173S; 1:1000), pERK (Cell Signaling ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... S6 (Cell Signaling; catalog no. 2211; 1:1000), CREB (Cell Signaling ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... AKT (Cell Signaling; catalog no. 4691; 1:1000), GAPDH (Cell Signaling ...
• An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

  Grace Y. Liu, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-cleaved Dcp-1(Cell Signaling Technology) at 1:100 ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Ser473-pAKT (1:500; Cell signaling Technology #4058), Ser235/236-pS6 (1:200 ...
• Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity

  Melica Nourmoussavi Brodeur, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-mouse (7076P2, Cell Signaling; 1:10000) antibodies were used respectively ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Ser473-pAKT (1:1000; Cell Signaling Technology #4058), pAKT (1:1,000 ...
• Stress-induced vascular remodeling: novel insight into the role of omega-3 fatty acid metabolite, 4-oxoDHA

  Makoto Nishimori, et al., bioRxiv - Biochemistry 2023

  Quote: ... rabbit anti-NRF2 (1:500, Cell Signaling #D129C), rabbit anti-heme oxygenase-1 (1:2000 ...
• IL-1Ra and CCL5, but not IL-10, are promising targets for treating SMA astrocyte-driven pathology

  Reilly L. Allison, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-phNFkB (Cell Signaling, #3033, 1:1000), mouse anti-TGFβ (ThermoFisher ...
• Chronic chemogenetic activation of hippocampal progenitors enhances adult neurogenesis and modulates anxiety-like behavior and fear extinction learning

  Megha Maheshwari, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-DCX (1:250; Cell Signaling). Sections were then incubated with a secondary antibody cocktail ...
• Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function

  KR Bowles, et al., bioRxiv - Neuroscience 2023

  Quote: ... and OCT4A (Cell Signaling Technologies 2840S, 1:400). Secondary antibodies were AlexaFluors Goat-anti-mouse 488 and Donkey-anti-Rabbit 568 ...
• The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC reprogramming

  Mercedes Barrero, et al., bioRxiv - Genetics 2023

  Quote: ... rabbit anti STAT3 1:1000 (Cell Signaling, 12640S), rabbit anti phospho STAT3 Tyr705 1:1000 (Cell signaling ...
• ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney disease

  Tomoki Yanagi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Raptor (1:1000, #2280, Cell Signaling Technology), anti-phospho-Raptor (Ser792 ...
• An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes

  Simone Caielli, et al., bioRxiv - Immunology 2023

  Quote: ... anti-cleaved (mature) Caspase 1 (Cell Signaling #4199S), anti-AIM2 (Cell Signaling #12948S) ...
• Aberrant activation of the innate immune sensor PKR by self dsRNA is prevented by direct interaction with ADAR1

  Ketty Sinigaglia, et al., bioRxiv - Immunology 2023

  Quote: ... Rig-I 1:500 (Cell Signaling, [D14G6] #3743), Mda5 1:1000 (Cell Signaling [D74E4],#5321) ...
• Aberrant activation of the innate immune sensor PKR by self dsRNA is prevented by direct interaction with ADAR1

  Ketty Sinigaglia, et al., bioRxiv - Immunology 2023

  Quote: ... HA tag Rabbit 1:1000 (Cell signaling #3724), HA tag mouse 1:2000 (antibodies.com #A85278 ...
• Illuminating the Terminal Nerve: Uncovering the Link between GnRH-1 and Olfactory Development

  Enrico Amato Jr, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit-α-Map2 (1:200, Cell Signaling Technology), rabbit-α-Cleaved Caspase 3 (1:1000 ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (Cell Signaling; catalog no. 2118; 1:2000), pS6 (Cell Signaling ...
• Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation

  Kyle Brown, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-BMI1 antibody (1:500; Cell Signaling; 6964S); and anti-H3K27me3 antibody (1:4000 ...
• NECAB2 participates in an endosomal pathway of mitochondrial stress response at striatal synapses

  Diones Bueno, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-COXIV 1:1000 (Cell Signaling, Danvers, USA), anti-b-tubulin 3 ...
• NECAB2 participates in an endosomal pathway of mitochondrial stress response at striatal synapses

  Diones Bueno, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-VDAC 1:1000 (Cell Signaling, Danvers, USA), anti-COXIV 1:1000 (Cell Signaling ...