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4451 - 4500 of 10000+ citations for 6 Hydroxy 1 2 benzisothiazole 3 carboxylic acid since 2019

• PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth

  Abigail H. Cleveland, et al., bioRxiv - Neuroscience 2022

  Quote: ... H2AK119ub (Cell Signaling, #8240; 1:500 dilution), H3K27Ac (Cell Signaling ...
• Direct control of translational elongation by TAOK2β highlights altered protein synthesis as a fundamental underlying component of autism

  Melad Henis, et al., bioRxiv - Neuroscience 2022

  Quote: ... (Cell Signaling Technology; 2366, WB 1:1,000) and mouse anti-eEF2 ...
• Direct control of translational elongation by TAOK2β highlights altered protein synthesis as a fundamental underlying component of autism

  Melad Henis, et al., bioRxiv - Neuroscience 2022

  Quote: ... (Cell Signaling Technology; 2625, WB 1:1,000); mouse anti-His-Tag (27E8) ...
• Direct control of translational elongation by TAOK2β highlights altered protein synthesis as a fundamental underlying component of autism

  Melad Henis, et al., bioRxiv - Neuroscience 2022

  Quote: ... (Cell Signaling Technology; 4970, WB 1:5,000); rabbit anti-Myc-Tag (71D10) ...
• DHHC3 mediated Cadm4 palmitoylation regulates myelination in CNS

  Yanli Chang, et al., bioRxiv - Neuroscience 2022

  Quote: ... MAG (Cell Signaling, Cat# 9043S, 1:1000), Flag (Abclonal ...
• FGF21 Counteracts Alcohol Intoxication by Activating Noradrenergic Neurons

  Mihwa Choi, et al., bioRxiv - Neuroscience 2022

  Quote: ... cFos (Cell Signaling Technology, 1:1000 dilution), red fluorescent protein (Rockland ...
• DHHC3 mediated Cadm4 palmitoylation regulates myelination in CNS

  Yanli Chang, et al., bioRxiv - Neuroscience 2022

  Quote: ... HSP90 (Cell Signaling, Cat# 4874S, 1:1000), MAG (Cell Signaling ...
• Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

  Michelle M. Frank, et al., bioRxiv - Neuroscience 2022

  Quote: ... Rabbit anti-NPY (Cell Signaling, 1:1,000), Goat anti-CALB2(Swant ...
• PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth

  Abigail H. Cleveland, et al., bioRxiv - Neuroscience 2022

  Quote: ... H3K4me3 (Cell Signaling, #9751; 1:500 dilution), H2AK119ub (Cell Signaling ...
• Charting functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

  Alexander Hanzl, et al., bioRxiv - Molecular Biology 2022

  Quote: ... VHL (1:1000, Cell Signaling Technology, 2738), ACTIN (1:5000 ...
• Charting functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

  Alexander Hanzl, et al., bioRxiv - Molecular Biology 2022

  Quote: ... SMARCA2 (1:1000, Cell Signaling Technology, #6889), cMYC (1:1000 ...
• ISG15 Monomer Promotes IFNα-mediated Antiviral Activity against Pseudorabies Virus by Facilitating phosphorylation of STAT1/STAT2

  Huimin Liu, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-IRF9 (1:3000 dilution; Cell Signaling); anti-USP18 (1:3000 dilution ...
• ISG15 Monomer Promotes IFNα-mediated Antiviral Activity against Pseudorabies Virus by Facilitating phosphorylation of STAT1/STAT2

  Huimin Liu, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-STAT1 (1:3000 dilution; Cell Signaling); anti-phospho-Tyr690 STAT2 ...
• Unexpected proteinopathies in hippocampal PDE11A4 promote age-related cognitive decline of social associative memories

  K Pilarzyk, et al., bioRxiv - Neuroscience 2022

  Quote: ... CREB (Cell Signaling #4820 at 1:10,000) as well as synaptophysin (BD Transduction #611880 at 1:200,000 ...
• A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding

  Lei Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pRB (Cell Signaling, D20B12, 1:500), anti-SATB2 (Millipore ...
• Charting functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

  Alexander Hanzl, et al., bioRxiv - Molecular Biology 2022

  Quote: ... CDK9 (1:1000, Cell Signaling Technology, 2316S), CRBN (1:2000 ...
• ISG15 Monomer Promotes IFNα-mediated Antiviral Activity against Pseudorabies Virus by Facilitating phosphorylation of STAT1/STAT2

  Huimin Liu, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-STAT2 (1:3000 dilution; Cell Signaling); anti-IRF9 (1:3000 dilution ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... p-p38 (Cell Signaling, #4511, 1:1000), Erk (Cell Signaling ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... p-Erk (Cell Signaling, #9101, 1:1000), Jnk (Cell Signaling ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... p-Jnk (Cell Signaling, #4668, 1:1000), Pten (Cell Signaling ...
• Microglial TNFα orchestrates brain phosphorylation during the sleep period and controls homeostatic sleep

  Maria J Pinto, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-vinculin (1:5000, Cell Signaling, 13901) and anti-tubulin (1:10000 ...
• The Ketogenic Diet Metabolite β-Hydroxybutyrate Promotes Mitochondrial Elongation via Deacetylation and Improves Autism-like Behavior in Zebrafish

  Golam M. Uddin, et al., bioRxiv - Molecular Biology 2022

  Quote: ... MFF (Cat#, Cell Signaling, USA; 1:1000); and DRP1 S637 (Cat# 4867SS ...
• Subcellular proteome of radial glia reveals non-muscle myosins control basal endfeet to mediate interneuron organization

  Brooke R D’Arcy, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-CC3 (Cell Signaling, 9661 1:400), anti-Ki67 (Cell Signaling ...
• Subcellular proteome of radial glia reveals non-muscle myosins control basal endfeet to mediate interneuron organization

  Brooke R D’Arcy, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-p73 (Cell Signaling, 14620S 1:250), anti-Calretinin (Swant ...
• Mapping PTBP splicing in human brain identifies targets for therapeutic splice switching including SYNGAP1

  Jennine M. Dawicki-McKenna, et al., bioRxiv - Molecular Biology 2022

  Quote: ... PSD-95 (Cell Signaling 3450, 1:200). Cells were subsequently treated with secondary antibodies goat anti-IgG1-Alexa488 (for MAP2) ...
• Frontal cortical regulation of neurogenesis and cellular proliferation in the ventral subventricular zone

  Moawiah M Naffaa, et al., bioRxiv - Neuroscience 2022

  Quote: ... Doublecortin (#4604S, 1:200, Cell Signaling Technology), Doublecortin (#MA5-17066 ...
• Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

  Michelle M. Frank, et al., bioRxiv - Neuroscience 2022

  Quote: ... Rabbit anti-NPY (Cell Signaling, 1:500); Goat anti-ChAT (Millipore Sigma ...
• PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth

  Abigail H. Cleveland, et al., bioRxiv - Neuroscience 2022

  Quote: ... pRB diluted 1:3000 (Cell Signaling, #8516), cC3 diluted 1:400 (Biocare Medical ...
• Direct control of translational elongation by TAOK2β highlights altered protein synthesis as a fundamental underlying component of autism

  Melad Henis, et al., bioRxiv - Neuroscience 2022

  Quote: ... (Cell Signaling Technology; 3691, WB 1:1,000); and mouse anti-eEF2K antibody (C-12) ...
• Familial Alzheimer’s disease mutation undermines axonal transport by enhancing dynactin recruitment to the APP motor assemblies

  Monica Feole, Gorazd B. Stokin, bioRxiv - Neuroscience 2022

  Quote: ... anti-Mouse 1:2000 (Cell signaling 7076), anti-Goat 1:1000 (Santa Cruz 2354) ...
• Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity

  Aparajitha Vaidyanathan, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Drosha (1:1000) (Cell Signaling #D28B1), anti-Exportin 5 (1:1000 ...
• Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4

  Michio Inoue, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-GFP (Cell Signaling Technology, 1:1000), anti-histone H3 (abcam ...
• E3-specific degrader discovery by dynamic tracing of substrate receptor abundance

  Alexander Hanzl, et al., bioRxiv - Molecular Biology 2022

  Quote: ... VHL (1:1000, Cell Signaling Technology, 2738), ACTIN (1:5000 ...
• Deletion of TRPC6, an autism risk gene, induces hyperexcitability in cortical neurons derived from human pluripotent stem cells

  Kyung Chul Shin, et al., bioRxiv - Neuroscience 2022

  Quote: ... TBR2 (Rabbit,1:300, Cell signaling: 66325), CTIP2 (Rabbit ...
• Deletion of TRPC6, an autism risk gene, induces hyperexcitability in cortical neurons derived from human pluripotent stem cells

  Kyung Chul Shin, et al., bioRxiv - Neuroscience 2022

  Quote: ... BRN2 (Rabbit, 1:200, Cell signaling:12137), GFAP (Chicken ...
• E3-specific degrader discovery by dynamic tracing of substrate receptor abundance

  Alexander Hanzl, et al., bioRxiv - Molecular Biology 2022

  Quote: ... CDK9 (1:1000, Cell Signaling Technology, 2316S), CRBN (1:2000 ...
• N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

  Sylvia Varland, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-UBR5 (Cell Signaling, 65344, 1:1000), anti-KCMF1 (Sigma-Aldrich ...
• Hepatic MCPIP1 protein levels are reduced in NAFLD patients and are predominantly expressed in cholangiocytes and liver endothelium

  Natalia Pydyn, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-PPARγ (1:1000; Cell Signaling), rabbit anti-PPARα (1:1000 GeneTex) ...
• A metabolic map of the DNA damage response identifies PRDX1 in nuclear ROS scavenging and aspartate synthesis

  Amandine Moretton, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Tubulin (diluted 1:10,000, DM1A Cell Signaling), Vinculin (diluted 1:1,000 ...
• A metabolic map of the DNA damage response identifies PRDX1 in nuclear ROS scavenging and aspartate synthesis

  Amandine Moretton, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Vinculin (diluted 1:1,000, #13901 Cell Signaling), H3 (diluted 1:10,000 ...
• E3-specific degrader discovery by dynamic tracing of substrate receptor abundance

  Alexander Hanzl, et al., bioRxiv - Molecular Biology 2022

  Quote: ... SMARCA2 (1:1000, Cell Signaling Technology, #6889), cMYC (1:1000 ...
• Hepatic MCPIP1 protein levels are reduced in NAFLD patients and are predominantly expressed in cholangiocytes and liver endothelium

  Natalia Pydyn, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-IR (1:1000; Cell Signaling), anti-p-AktSer473 (1:1000 ...
• Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ears

  Tian Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... and CALBINDIN1 (1:500, Cell Signaling Technologies). Secondary antibodies were conjugated with FITC (1:500 ...
• RNA dicing regulates the expression of an oncogenic JAK1 isoform

  Yuval Malka, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Phospho-JAK1 (Cell signaling 3331, 1:1000), Phospho-JAK1 (Cell signaling 74129 ...
• RNA dicing regulates the expression of an oncogenic JAK1 isoform

  Yuval Malka, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Phospho-JAK1 (Cell signaling 74129, 1:1000), Non-Phospho JH1 JAK1 (Abcam ab47435 ...
• R-Loop Functions in Brca1-Associated Mammary Tumorigenesis

  Huai-Chin Chiang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-γH2AX (Cell Signaling, 9718, 1:500), and anti-RAD51 (Santa Cruz ...
• An unconventional autophagic pathway that inhibits ATP secretion during apoptotic cell death

  Elena Terraza-Silvestre, et al., bioRxiv - Cell Biology 2024

  Quote: ... VPS34 (rabbit, Cell Signaling, 3358, 1/1000), ATG14 (rabbit ...
• Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit ITGB1 (1:1000, Cell Signaling Technology), mouse H3.1/3.2 (1:5000 ...
• Hypoxia and TNF-alpha modulate extracellular vesicle release from human induced pluripotent stem cell-derived cardiomyocytes

  Margarida Viola, et al., bioRxiv - Cell Biology 2024

  Quote: GAPDH (Cell Signaling Technology, 2118, 1:1000), GM130 (BD Biosciences ...
• TKI Type Switching Overcomes ROS1 L2086F in ROS1 Fusion-Positive Cancers

  Rajat Thawani, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ROS1 (D4D6; 1:1,000; Cell Signaling Technology), phospho-p44/42 MAPK (9101 ...