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4451 - 4500 of 10000+ citations for 6 4 METHOXY PHENYL 3 METHYL IMIDAZO 2 1 B THIAZOLE 5 CARBALDEHYDE since 2019

• Chronic pharmacologic manipulation of dopamine transmission ameliorates metabolic disturbance in syndrome caused by mutated trappc9

  Yan Li, et al., bioRxiv - Neuroscience 2024

  Quote: ... PSD95 (1:1000, Cell Signaling, 2507S), Dlg2 (1:200 ...
• Polymeric nanoparticles delivery of AMPK activator 991 prevents its toxicity and improves muscle homeostasis in Duchenne Muscular Dystrophy

  Ilaria Andreana, et al., bioRxiv - Pathology 2024

  Quote: ... ACC (#3676, Cell Signaling, 1:1000), p-RAPTOR (# ...
• Dual agonism of sodium iodide symporter function in vivo

  Katie Brookes, et al., bioRxiv - Cancer Biology 2024

  Quote: ... NPL4 (1:500; Cell Signaling Technology), VCP (1:1000 ...
• Systemic Dosing of Virus-derived Serpin Improves Survival and Immunothrombotic Damage in Murine Colitis

  Liqiang Zhang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... M2 macrophage arginase-1 (Cell Signaling, 93668 ...
• Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

  Moriah R. Arnold, et al., bioRxiv - Cell Biology 2024

  Quote: ... γH2AX (Cell Signaling #9718, 1:500), Treacle (Sigma-Aldrich #GW22821 ...
• Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

  Moriah R. Arnold, et al., bioRxiv - Cell Biology 2024

  Quote: ... or γH2AX (1:1,000; Cell Signaling) and 1 hour at RT with IRDye 680CW Goat anti-mouse (1:10,000 ...
• Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy

  Nipun Verma, et al., bioRxiv - Genetics 2024

  Quote: ... IRF3 (Cell Signaling # 11904, 1:1000), GAPDH (ThermoFisher # MA1-16757 ...
• The novel linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse embryonic development

  Sung-Eun Kim, et al., bioRxiv - Genetics 2024

  Quote: ... HA (Cell signaling #3724; 1:1000), Flag (Sigma F1804 ...
• Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy

  Nipun Verma, et al., bioRxiv - Genetics 2024

  Quote: ... TBK1 (Cell Signaling # 3504, 1:1000), IRF3 (Cell Signaling # 11904 ...
• Nephronophthisis-associated FBW7 mediates cyst-dependent decline of renal function in ADPKD

  Maulin Mukeshchandra Patel, et al., bioRxiv - Genetics 2024

  Quote: ... VIMENTIN (1:200, Cell Signaling 5741), α-SMOOTH MUSCLE ACTIN (1:200 ...
• Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation

  Tanusri Roy, et al., bioRxiv - Cell Biology 2024

  Quote: ... γ-H2AX (1:500, Cell signaling Technologies), Lamin A/C (1:400 ...
• LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3

  Ningbo Zheng, et al., bioRxiv - Immunology 2024

  Quote: ... (1:4000, #7076, Cell Signaling Technology).
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... BRD4 (Cell signaling, 13440S, 1:50), H3K27ac (Active motif ...
• Metastatic site influences driver gene function in pancreatic cancer

  Kaloyan M. Tsanov, et al., bioRxiv - Cancer Biology 2024

  Quote: ... RUNX1 (Cell Signaling #8529, 1:1000), and Actin-HRP (Sigma #A3854 ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... S6 (Cell Signaling, 2217T, 1:1000), Phosphor-S6 (Cell Signaling ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... MYC (Cell signaling, 13987S, 1:50), Pol II (Cell signaling ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... H3K27me3 (Cell signaling, 9733s, 1:50), and IgG (EpiCypher ...
• Human MX1 orchestrates the cytoplasmic sequestration of neo-synthesized influenza A virus vRNPs

  Joe McKellar, et al., bioRxiv - Microbiology 2024

  Quote: ... Rab11 (Cell Signaling, 5589 1/50), Rab11a (Proteintech ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... TBK1 (Cell Signaling #38066S, 1:1000), IRF3 (Cell Signaling #4302S ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... cGAS (Cell Signaling #15102S, 1:1000), TBK1 (Cell Signaling #38066S ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... MX1 (Cell Signaling #37849, 1:1000), IFIT1 (Cell Signaling #14769 ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... STING (Cell Signaling #13647S, 1:1000), cGAS (Cell Signaling #15102S ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... STAT1 (Cell Signaling #14994, 1:1000), MX1 (Cell Signaling #37849 ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... IFIT1 (Cell Signaling #14769, 1:1000), STING (Cell Signaling #13647S ...
• A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

  Maritza Puray-Chavez, et al., bioRxiv - Microbiology 2024

  Quote: ... IRF3 (Cell Signaling #4302S, 1:1000), SARS-CoV-2 Nucleocapsid (Sino Biological # 40588-T62 ...
• Microbial Metabolite Trimethylamine N-Oxide Promotes Campylobacter jejuni Infection by Escalating Intestinal Inflammation, Epithelial Damage, and Barrier Disruption

  Caitlyn B. Smith, et al., bioRxiv - Microbiology 2024

  Quote: ... zonula occludens-1 (Cell Signaling Technologies), zonula occludens-2 (ZO-2 ...
• Chitinase 3-like-1 (CHI3L1) Inhibits Innate Anti-Tumor and Tissue Remodeling Immune Responses by Regulating CD47-SIRPα and CD24-Siglec10-Mediated Phagocytosis

  Bing Ma, et al., bioRxiv - Immunology 2024

  Quote: ... SHP-1 (Cell Signaling Technology, C14H6), and SHP-2 (Cell Signaling Technology ...
• Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

  Devon E. Mason, et al., bioRxiv - Cell Biology 2024

  Quote: ... TAZ (1:250, Cell Signaling, 4883), Vinculin (1:100 ...
• Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

  Devon E. Mason, et al., bioRxiv - Cell Biology 2024

  Quote: ... pMLC (1:200, Cell signaling, 3675). Primary antibodies were detected secondaries antibodies diluted in PBS with 1% goat serum ...
• Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

  Devon E. Mason, et al., bioRxiv - Cell Biology 2024

  Quote: ... TAZ (1:1000, Cell Signaling, 4883), pMLC (1:1000 ...
• Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

  Devon E. Mason, et al., bioRxiv - Cell Biology 2024

  Quote: ... GAPDH (1:3000, Cell Signaling, 5174) were incubated overnight in blocking buffer with .2% tween-20 (Fisher Scientific) ...
• Defects in AMPAR trafficking and microglia activation underlie socio-cognitive deficits associated to decreased expression of Phosphodiesterase 2A

  Sébastien Delhaye, et al., bioRxiv - Animal Behavior and Cognition 2023

  Quote: ... anti-GluR1 (Cell Signaling, 1:1000) and anti-Ser845-GluR1 (Cell Signaling ...
• Cyclin A/Cdk1 promotes chromosome alignment and timely mitotic progression

  Sarah Y. Valles, et al., bioRxiv - Cell Biology 2023

  Quote: ... H3pS10 (1:1000; Cell Signaling: #53348). Secondary antibodies for Western blotting are IRDye 680RD Goat anti-Mouse (1:10000 or 1:20000 ...
• Modeling aging and retinal degeneration with mitochondrial DNA mutation burden

  John Sturgis, et al., bioRxiv - Cell Biology 2023

  Quote: ... Tubulin (Cell Signaling, 2144, 1:5000), or GAPDH (Proteintech ...
• Mitochondrial Apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways

  Melissa Lubeck, et al., bioRxiv - Cell Biology 2023

  Quote: ... DRP1 (Cell Signaling Technology, 1:1000), β-Actin (Invitrogen ...
• The scramblases VMP1 and TMEM41b are required for primitive endoderm specification by targeting WNT signaling

  Markus Holzner, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Rab7 (1:200, Cell Signaling, # 9367S) Sox1 (1:50 ...
• Parkinson’s genes orchestrate pyroptosis through selective trafficking of mtDNA to leaky lysosomes

  Mai Nguyen, et al., bioRxiv - Cell Biology 2023

  Quote: ... LAMP1 (Cell signaling, 9091, 1:500), TOMM40 (Proteintech ...
• The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages

  Mays Mohammed Salih, et al., bioRxiv - Immunology 2023

  Quote: ... STAT3 (1:500, Cell Signaling, 9139S), pJAK3 (1:500 ...
• The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages

  Mays Mohammed Salih, et al., bioRxiv - Immunology 2023

  Quote: ... pSTAT3 (1:500, Cell Signaling, 9138S), STAT3 (1:500 ...
• The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages

  Mays Mohammed Salih, et al., bioRxiv - Immunology 2023

  Quote: ... pJAK3 (1:500, Cell Signaling, 5031S), or JAK3 (1:500 ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 4EBP1 (Cell Signaling, 9644S, 1:1000), Phosphor-4EBP1 (Cell Signaling ...
• Co-Essentiality Analysis Identifies PRR12 as a Regulator of Cohesin and Genome Integrity

  Alexandra L. Nguyen, et al., bioRxiv - Cell Biology 2024

  Quote: ... CTCF (1:500, Cell Signaling; D31H2), SMC4 (1:500 ...
• Dual agonism of sodium iodide symporter function in vivo

  Katie Brookes, et al., bioRxiv - Cancer Biology 2024

  Quote: ... VCP (1:1000; Cell Signaling Technology) and β-actin (1:10000 ...
• Tumor cell-adipocyte gap junctions activate lipolysis in breast cancer

  Roman Camarda, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HSL (4107, Cell Signaling, 1:1000), HNF4α (ab41898 ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... PARP (Cell Signaling, 46D11, 1:1000), BiP (Cell Signaling ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... Calnexin (Cell Signaling, C5C9, 1:1000), MARCH5 (abcam ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... eif2α (total, Cell Signaling, 1:1000), ATF4 (Cell Signaling ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... BiP (Cell Signaling, C50B12, 1:1000), P- p38 (T180/Y182 ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... GAPDH (Cell Signaling, #2118, 1:4000), MEK1/2 (Cell Signaling 1:1000 ...
• AP2XII-2 coordinates transcriptional repression for Toxoplasma gondii sexual commitment

  Sandeep Srivastava, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-MYC (1:3000, Cell Signaling) or anti-SAG1 (1:5000 ...