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401 - 450 of 1758 citations for 4 2 Trimethylsilyl Ethyl Aniline since 2020

• Ellagic acid ameliorates atherosclerosis by targeting the epidermal growth factor receptor

  Ye-Wei Huang, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-ERK1/2 (4696S, Cell Signaling Technology, MA, USA), anti-phospho-ERK1/2 (4370S ...
• Neural stem cells protect blood-brain barrier integrity via the p38, JNK, and ERK1/2 pathways following intracerebral hemorrhage in rats

  Jing Sun, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-ERK1/2 (Cell Signaling, USA, 1:1000 dilution), anti-p38 (Cell Signaling ...
• Serine arginine-rich splicing factor (SRSF7) cooperates with the histone methyltransferase KMT5a to promote the type I interferon response via transcriptional activation of IRF7

  Haley M. Scott, et al., bioRxiv - Immunology 2023

  Quote: ... or 2 µg of isotype control (IgG, Cell Signaling), 5ul Y701 STAT1 (Cell Signaling) ...
• Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer

  E. M. Poursani, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p44/42 MAPK (ERK1/2) (9102S, Cell Signaling Technology), MMP-9 (D6O3H ...
• Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis

  Abir Mukherjee, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HK-2 (Cell Signaling Technology, cat# 2867, 1:1000), p-STAT3 Tyr 708 (Cell Signaling Technology ...
• Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells

  Yueyang Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-phospho Myosin Light Chain 2 (Cell Signaling 3671) and secondary antibody anti-rabbit AlexaFluor 488 (Invitrogen A-21441) ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... phospho-ERK1/2 (1:200; 4370; Cell Signaling Technology), phospho-AKT (1:8,000 ...
• Competitive, connective and allosteric Nanobodies that modulate the SOS1•RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design

  Baptiste Fischer, et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit monoclonal ERK1/2 (1:50, Cell Signaling #4696), and mouse monoclonal Flag antibody (clone M2 ...
• Peripheral extracellular vesicle-derived miR-150-3p exacerbates acute kidney injury following acute pancreatitis by promoting ferroptosis through FTH1 signaling

  Ji-tao Cui, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Cox-2 (1:1,000, 9461, Cell Signaling Technology), anti-β-actin (1:2,000 ...
• Antagonistic pleiotropy plays an important role in governing the evolution and genetic diversity of SARS-CoV-2

  Ding-Chin Lee, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... rabbit anti-SARS-CoV-2 envelope (Cell signaling, #74698), rabbit anti-GAPDH (Genetex ...
• Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation

  Eun Hye Park, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERK1/2 (Cell Signaling Technology, Cat.No.9102S, 1:1000), phospho-4EBP1 (Cell Signaling Technology ...
• Actin polymerization drives lumen formation in a human epiblast model

  Dhiraj Indana, et al., bioRxiv - Developmental Biology 2023

  Quote: ... phospho- myosin light chain 2 (Cell Signaling Technology #3674), Arp2/3 complex (Sigma-Aldrich MABT95) ...
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  Tiantian Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Mek1/2 (1:1,000, Cell Signaling Technology, Cat# 9122), alpha-tubulin (Sigma ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-MAPKAPK-2 (1:1000, Cell Signaling 3042), rabbit anti-phospho-MAPKAPK-2 (Thr222 ...
• Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

  Lorenz Waltl, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-MEK1/2 (1:1000; # 9122; Cell Signaling), rabbit anti-phospho-MEK1/2 (1:1000 ...
• Viral Insulin/IGF-like Peptides Selectively Activate Host Insulin/IGF Signaling pathways during Grouper Iridovirus Infection

  Aurelien Chuard, et al., bioRxiv - Microbiology 2024

  Quote: ... p44/42 MAPK (Erk1/2) Antibody (Cell Signaling #9102); β-Actin (D6A8 ...
• Braf-mutant Schwann cells divert to a repair phenotype to induce congenital demyelinating neuropathy

  Elise Marechal, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit polyclonal anti-Erk1/2 (#9102; Cell Signaling Technology), rabbit monoclonal anti-Jun (60A8 ...
• Synthetic G protein-coupled receptors for programmable sensing and control of cell behavior

  Nicholas A. Kalogriopoulos, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... p44/42 MAPK (Erk1/2; Cell Signaling Technology #9107), and β-Tubulin (Cell Signaling Technology #86298).
• Multifunctional molecular hybrid for targeted colorectal cancer cells: Integrating doxorubicin, AS1411 aptamer, and T9/U4 ASO

  Kanpitcha Jiramitmongkon, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Bcl–2 (1:1000; 25 – 28 kDa, Cell signaling), and Bax (1:1000 ...
• Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

  Qiwang Xiang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... SARS-CoV-2 Membrane protein (Cell Signaling Technology, 15333S); SARS-CoV-2 Envelope protein (Cell Signaling Technology ...
• Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus

  Qiwang Xiang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... SARS-CoV-2 Envelope protein (Cell Signaling Technology, 74698S); furin (Proteintech ...
• Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression

  Nathaniel Shannon, et al., bioRxiv - Cell Biology 2024

  Quote: ... total MEK1/2 (1:1000, Cell Signaling Technology #9122), Cofilin (1:1000 ...
• Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase

  Erin Skeens, et al., bioRxiv - Biochemistry 2024

  Quote: ... and anti-phospho-ERK1/2 (Cell Signaling cat# 9101) antibodies ...
• Kinase Plasticity in Response to Vandetanib Enhances Sensitivity to Tamoxifen and Identifies Co-Treatment Strategies in Estrogen Receptor Positive Breast Cancer

  Rasha T. Kakati, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Cell Signaling Technologies), RET (Abcam) ...
• Proteomic analysis reveals complex interactions between PERK/ISR and MAPK1 in translational control in a phenotypic toxin model of Parkinson’s disease expressing PINTAC peptides

  Girish N Nallur, bioRxiv - Systems Biology 2024

  Quote: ... RSK1/2/3 (Cat. No. 9355; Cell Signaling Technology), pRPS6 (Cat ...
• The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

  Patience O. Obi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-Bcl-2 (3498, Cell Signaling, 1:1000), rabbit anti-Bax (2772 ...
• XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

  Andrew E. Evans, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-COX-2 (1/300; Cell Signaling, Cat# 12282S), anti-Ki67 (1/200 ...
• XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

  Andrew E. Evans, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-COX-2 (1/1000; Cell Signaling, Cat # 12282S), anti-Actin (1/5000 ...
• Neuromodulation of Behavioral Specialization: Tachykinin Signaling Inhibits Task-specific Behavioral Responsiveness in Honeybee Workers

  Bin Han, et al., bioRxiv - Evolutionary Biology 2021

  Quote: ... The membranes were blocked for 2 hours at room temperature and then incubated with rabbit monoclonal anti-pERK1/2 antibody (Cell Signaling Technology, USA) and anti-rabbit horseradish peroxidase-conjugated secondary antibody (Cell Signaling Technology ...
• Using rat operant delayed match-to-sample task to identify neural substrates recruited with increased working memory load

  Christina Gobin, Lizhen Wu, Marek Schwendt, bioRxiv - Neuroscience 2020

  Quote: ... PKC substrate antibody selectively detects proteins with phosphorylated PKC consensus sites (phosphorylated Ser residues surrounded by Arg or Lys at the –2 and +2 positions and a hydrophobic residue at the +1 position, Cell Signaling, Danvers, MA). Next ...
• Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo

  Mohamed R. Ahmed, et al., bioRxiv - Neuroscience 2023

  Quote: ... Doubly phosphorylated (active) ERK1/2 was detected with a phospho-ERK-specific [phosphor-ERK1/2(Thr202/Tyr204)] mouse monoclonal antibody (Cell Signaling, cat.# 9106) at 1:2,000 dilution ...
• The protein phosphatases MoPtc1 and MoPtc2 are induced during pathogen-host interactions and play synergistic roles in regulating MAPK pathways in Magnaporthe oryzae

  Wilfred M. Anjago, et al., bioRxiv - Molecular Biology 2022

  Quote: ... phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (D13.14.4E) Rabbit mAb and p44/42 MAPK (Erk1/2) antibodies (Cell Signaling Technology, Beverly, MA, USA) and affinity purified goat anti-rabbit & mouse antibody conjugated to horseradish peroxidase (Abmart ...
• Decreased Astrocytic CCL5 by MiR-324-5p Ameliorates Ischemic Stroke Injury via CCR5/ERK/CREB Pathway

  Jingxiu Li, et al., bioRxiv - Neuroscience 2024

  Quote: ... The PVDF membranes were blocked with 5% BSA and probed with primary antibodies (phospho-ERK1/2, Abcam, ab76299; ERK1/2, Abcam, ab184699; phospho-CREB, Abcam, ab32096; CREB, Cell Signaling Technology, 9197) at 4 °C overnight ...
• Stat3 co-operates with mutant Ezh2^Y641F to regulate gene expression and limit the anti-tumor immune response in melanoma

  Sarah M. Zimmerman, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Immunoprecipitations were performed overnight at 4°C using anti-Stat3 (Cell Signaling #9139) and anti-Ezh2 (Cell Signaling #5246 ...
• Endothelial Unc5B controls blood-brain barrier integrity

  Kevin Boyé, et al., bioRxiv - Cell Biology 2021

  Quote: ... The following antibodies were incubated overnight at 4°C: Unc5B (Cell Signaling, 13851S), Robo4 (Invitrogen ...
• Staufen1 localizes to the mitotic spindle and controls the transport of RNA populations to the spindle

  Sami Hassine, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Anti-RPS6 (2212, batch number 4. 1/1000) was purchased from Cell Signaling. Anti-RPL26 ...
• The CDK8 inhibitor DCA promotes a tolerogenic chemical immunophenotype in CD4⁺ T cells via a novel CDK8-GATA3-FOXP3 pathway

  Azlann Arnett, et al., bioRxiv - Immunology 2021

  Quote: ... 4 μl of anti-GATA3 or isotype control (Cell Signaling Technologies, Danvers, MA) added and sample incubated at 4°C with end over end rotation ...
• Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal

  Joshua D. Rieskamp, et al., bioRxiv - Neuroscience 2022

  Quote: ... and incubated overnight at 4°C in mouse anti-mTOR (Cell Signaling 4517) and rabbit anti-phospho(p)-mTOR(Ser2448 ...
• An ATF4-centric regulatory network is required for the assembly and function of the OXPHOS system

  Umut Cagin, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and sequentially probed with specific antibodies against ATF4 (Cell Signaling ATF-4 (D4B8), #11815 ...
• Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension

  Brandon Elliott, et al., bioRxiv - Physiology 2024

  Quote: ... The following primary antibodies were then applied: GATA-4 (1:400; Cell Signaling), atrial natriuretic peptide (1:100 ...
• An O-GlcNAc transferase pathogenic variant that affects pluripotent stem cell self-renewal

  Michaela Omelková, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Primary antibodies (Oct3/4 (D6C8T, Cell Signaling Technology, catalogue number 83932, 1:1000), Sox2 (D9B8N ...
• Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity

  Jessica Furtado, et al., bioRxiv - Cell Biology 2023

  Quote: ... The following antibodies were incubated overnight at 4°C: Unc5B (Cell Signaling, 13851S), Netrin-1 (R&D ...
• Metformin impairs trophoblast metabolism and differentiation in dose dependent manner

  Sereen K. Nashif, et al., bioRxiv - Cell Biology 2023

  Quote: ... Blots were stained overnight at 4 C with total AMPK (Cell Signaling Technology) and pAMPK Thr 172 (Cell Signaling Technology ...
• Microsporidian obligate intracellular parasites subvert autophagy of infected mammalian host cells to promote their own growth

  Johan Panek, et al., bioRxiv - Microbiology 2023

  Quote: ... 3% BSA overnight at 4 □C (rabbit α-LC3B 1:1000 – Cell Signaling/ #4108 ...
• Regulation of early growth response-1 (Egr-1) gene expression by Stat1-independent type I interferon signaling and respiratory viruses

  Chilakamarti V. Ramana, bioRxiv - Genomics 2020

  Quote: ... and subjected to immunoblotting with the antibodies for phosphorylated Erk-1/2 (Thr202/Tyr 204) or total Erk-1/2 from Cell Signaling Technology (Beverly, MA). Blots were visualized by enhanced chemiluminescence western detection system (Pierce ...
• Arrestin-3 agonism at D3 dopamine receptors defines a subclass of second generation antipsychotics that promotes drug tolerance

  Selin Schamiloglu, et al., bioRxiv - Neuroscience 2022

  Quote: ... blotted with mouse anti-ERK1/2 (p44/42 MAPK) and rabbit anti-phospho-ERK1/2 (p44/42 MAPK) (Cell Signaling Technologies 4696S and 4370S), both at 1:1000 in 2% BSA at room temperature for 2 hours ...
• Downstream branches of receptor tyrosine kinase signaling act interdependently to shape the face

  Nicholas Hanne, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Antibodies specific to phosphorylation on ERK1/2 threonine 202 and tyrosine 204 were used to detect pERK1/2 (1:100, 4370S, Cell Signaling Technology, Danvers, MA); antibodies specific to phosphorylation of serine 473 of Akt1/2/3 were used to detect pAkt (1:300 ...
• Partial epithelial-to-mesenchymal transition is prognostic and associates with Slug in head and neck cancer

  Henrik Schinke, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Ten to 50 μg of proteins were separated by 10 % SDS-PAGE and visualized with primary Slug or E-cadherin antibody (C19G7, Cell Signaling Technology, #9585, 1:1000, overnight at 4°C / 24E10, Cell Signaling Technology, #3195, 1:1000, overnight at 4°C) and horseradish peroxidase (HRP)-conjugated secondary antibodies (1:5000 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:500 Cell Signaling Technology), ERK1/2 (Thr202/Tyr204 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-MEK1/2 (Ser217/221) (1:500 Cell Signaling Technology), MEK1/2 (1:500 Cell Signaling Technology) ...