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401 - 450 of 2188 citations for 3 4 Fluorophenyl 5 fluorobenzoic acid since 2020

• Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis

  Andrew S. Riching, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-total Smad2/3 (Cell Signaling 8685S, 1:1000), anti-HA (Rockland 600-401-384 ...
• Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

  Saskia Hoffmann, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cleaved Caspase-3 (Asp175, 9661, Cell Signaling (1:1,000)) ...
• Selective interferon responses of intestinal epithelial cells minimize TNFα cytotoxicity

  Jacob A. Van Winkle, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-cleaved caspase 3 (Cell Signaling Technology, #9661S), secondary goat anti-mouse Alexa Fluor 555 ...
• c-Kit mediates cutaneous sensory axon innervation and multi-kinase inhibitor-induced neurotoxicity

  Adam M. Tuttle, et al., bioRxiv - Neuroscience 2021

  Quote: ... α-Cleaved Caspase-3 (1:1000, Cell Signaling, 9664P, RRID:AB_2070042), and α-acetylated Tubulin (1:1000 ...
• Nucleosomal Asymmetry Shapes Histone Mark Binding and Promotes Poising at Bivalent Domains

  Elana Bryan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Antibodies against histone H4 (Cell Signaling, 13919, lot 3), H3K4me3 (abcam ...
• Nucleosomal Asymmetry Shapes Histone Mark Binding and Promotes Poising at Bivalent Domains

  Elana Bryan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Antibody against histone H4 (Cell Signaling, 13919, lot 3) was used as a loading control ...
• Distinct roles for CDK-Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction

  Emilia Dimitrova, et al., bioRxiv - Molecular Biology 2021

  Quote: ... rabbit monoclonal anti-RING1B (5694, Cell Signaling, 3 μl), rabbit polyclonal anti-PCGF2 (sc-10744 ...
• Geminin is required for Hox gene regulation to pattern the developing limb

  Emily M.A. Lewis, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and rabbit anti-cleaved Caspase-3 (9661; Cell Signaling). Immunofluorescence imaging was performed on a Zeiss Axio Imager Z1 at 10X or 20X magnification.
• TNF controls a speed-accuracy tradeoff in the apoptotic decision to restrict viral spread

  Jennifer Oyler-Yaniv, et al., bioRxiv - Systems Biology 2020

  Quote: ... anti-Cleaved Caspase 3 (Cell Signaling Technologies, clone D175), phospho-STING (Cell Signaling Technologies ...
• High Affinity Chimeric Antigen Receptor with Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms

  Radhika Thokala, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-cleaved caspase 3 (Cell Signaling Technology, Danvers, MA), anti-EGFR (Thermo Fisher Scientific) ...
• Patient induced pluripotent stem cell-derived hepatostellate organoids establish a basis for liver pathologies in telomeropathies

  Young-Jun Choi, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-Cleaved Caspase-3 (Asp175) (Cell Signaling Technology), and mouse anti-HNF-4-alpha (Abcam) ...
• FGF2 modulates simultaneously the mode, the rate of division and the growth fraction in cultures of Radial Glia

  Mario Ledesma-Terrón, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-Cleaved Caspase 3 (1/1000, Cell Signaling 9661); and anti-KI67 (1/200 ...
• Molecular mechanisms underlying attenuation of live attenuated Japanese encephalitis virus vaccine SA14-14-2

  Pooja Hoovina Venkatesh, et al., bioRxiv - Cell Biology 2021

  Quote: ... Caspase-3 (Rabbit mAb 8G10; Cell Signaling Technology #9665), ATF4 (Rabbit mAb D4B8 ...
• Pro-apoptotic and anti-invasive properties underscore the tumor suppressing impact of myoglobin on subset of human breast cancer cells

  Mostafa A. Aboouf, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit anti-Smad2/3 polyclonal antibody (Cell Signaling, #5678) 1:1000 ...
• Lamin A/C phosphorylation at serine 22 is a conserved heat shock response to regulate nuclear adaptation during stress

  Laura Virtanen, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit monoclonal Caspase-3 (1:1000, 8G10, Cell Signaling), rabbit monoclonal cleaved caspase-3 (1:1000 ...
• TGF-β-R2 is required for HBP induced acute lung injury and vascular leakage for TGF-β/Smad/Rho signaling pathway activation

  Zixuan Liu, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-SMAD2/3 (D7G7, mAb #12470, Cell Signaling Technology), anti-SMAD2/3 (pAb AF6367 ...
• Human neutrophils direct epithelial cell extrusion to enhance intestinal epithelial host defense during Salmonella infection

  Anna-Lisa E. Lawrence, et al., bioRxiv - Microbiology 2022

  Quote: ... and anti-cleaved Caspase-3 (Cell Signaling, Cat# 9661) were added to the histology sections in blocking buffer overnight at 4°C ...
• Mutant SF3B1 promotes PDAC malignancy through TGF-β resistance

  Patrik T. Simmler, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-Cleaved Caspase 3 (Asp175) antibody (Cell Signaling Technology), anti-E-Cadherin (Clone 36 ...
• Bab2 activates JNK signaling to reprogram Drosophila wing disc development

  Yunpo Zhao, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-Cleaved Caspase 3 1:300 (Cell Signaling), rat anti-Bab2 1:10000 (Jean-Louis Couderc) ...
• Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma

  Chun-Chun Cheng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cleaved Caspase-3 (1:500, 9661, Cell Signaling Technology), PARP (1:1000 ...
• CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains

  Toshiya Kimura, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-cleaved Caspase-3 (Cell Signaling Technology, 9661), mouse anti-γ-tubulin (Sigma ...
• Targeting hypoxic habitats with hypoxia pro-drug evofosfamide in preclinical models of sarcoma

  Bruna V. Jardim-Perassi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cleaved Caspase-3 (CC3) (#9661, Cell Signaling, Danvers, MA) used as an apoptosis marker ...
• Identification of neural oscillations and epileptiform changes in human brain organoids

  Ranmal A. Samarasinghe, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Cleaved Caspase-3 (Asp175) (Cell Signaling 9661), rat anti-CTIP2 (BCL11B ...
• Generation of a DAT-Flp mouse line for intersectional genetic targeting of dopamine neuron subpopulations

  Daniel J. Kramer, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-Histone-3 (1:1500, Cell Signaling - 96C10); rabbit anti-VMAT2 (1:1400 ...
• ID1 and CEBPA Coordinate Epidermal Progenitor Cell Differentiation

  Christina Geraldine Kantzer, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Cleaved Caspase-3 (Cell Signaling Technology, #9661, 1:400), K10 (Biolegend ...
• Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue

  Joshua Poole, et al., bioRxiv - Physiology 2022

  Quote: ... using active caspase-3 (1:100, Cell Signaling Technologies). All brain sections were stained with a marker for neuronal nuclei ...
• Loss of PRMT2 in myeloid cells in normoglycemic mice phenocopies impaired regression of atherosclerosis in diabetic mice

  Beyza Vurusaner, et al., bioRxiv - Genetics 2022

  Quote: ... and cleaved caspase 3 (cat # 9664, Cell Signaling, MA) to detect apoptosis ...
• Estrogen exacerbates mammary involution through neutrophil dependent and independent mechanism

  Chew Leng Lim, et al., bioRxiv - Developmental Biology 2020

  Quote: ... or cleaved caspase 3 (1:100, #9661 Cell Signaling) followed by the DAB (3,3’-diaminobenzidine ...
• BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation

  Drake Edwards, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Cleaved Caspase 3 (1:500WB, 9664S, Cell Signaling Technology); SETX (1:500WB ...
• Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

  Tsunaki Hongu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-Caspase 3 (#9662, 1:1000 dilution, Cell signaling), anti-Vinculin (#4650 ...
• Bacillus thuringiensis bioinsecticides induce developmental defects in non-target Drosophila melanogaster larvae

  Marie-Paule Nawrot-Esposito, et al., bioRxiv - Physiology 2020

  Quote: ... Rabbit anti-Phospho-histone-3 (ref 9701S, Cell signaling) at 1/500 ...
• Neuroanatomical abnormalities in a nonhuman primate model of congenital Zika virus infection

  Adele M. H. Seelke, et al., bioRxiv - Neuroscience 2020

  Quote: ... cleaved caspase 3 (Cell Signaling, code 9661, 1:500) and SATB2 (Cell Signaling ...
• Cyclic pentapeptide cRGDfK enhances the inhibitory effect of sunitinib on TGF-β1-induced epithelial-to-mesenchymal transition in human non-small cell lung cancer cells

  Kyeong-Yong Park, Jiyeon Kim, bioRxiv - Biochemistry 2020

  Quote: ... and Smad2/3 were purchased from Cell Signaling Technology, Inc ...
• Hippo signaling promotes Ets21c-dependent apical cell extrusion in the Drosophila wing disc

  Xianlong Ai, Dan Wang, Junzheng Zhang, Jie Shen, bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-cleaved caspase-3 (1:200, Cell Signaling); mouse anti-Mmp1 (1:10 ...
• Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development

  Alexandr Samocha, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cleaved caspase-3 (1:300; 9661S) from Cell Signaling; Ki-67 (1:500 ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved Caspase-3 (1:200, Cell Signaling Technology, 9661) at 4 °C overnight ...
• Loss of BCL-3 sensitises colorectal cancer cells to DNA damage, revealing a role for BCL-3 in double strand break repair by homologous recombination

  Christopher Parker, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Cleaved caspase 3 (1:500, Cell Signaling Technology, #9661) and H2ax (1:50 ...
• Ex vivo infection of human skin with herpes simplex virus 1 reveals mechanical wounds as insufficient entry portals via the skin surface

  Nydia De La Cruz, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit anti-cleaved caspase 3 (1:400) (Cell Signaling), rabbit anti-loricrin (1:1000 ...
• Heterozygous loss of ZBTB38 leads to early embryonic lethality in mice via suppressing Nanog and Sox2

  Miki Nishio, et al., bioRxiv - Developmental Biology 2021

  Quote: ... immunostained with cleaved Caspase-3 antibody (#9664, Cell Signaling), Ki-67 antibody (#12202 ...
• Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2

  Polina Kosillo, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Histone- 3 (1:1500, Cell Signaling: 96C10); rabbit anti-VMAT2 (1:1000 ...
• Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing

  Nina Frey, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved Caspase 3 (1:400, Cell Signaling Technology, 9664). Donkey-anti-goat 488 and donkey-anti-rabbit 568 were used as secondary antibodies and counterstained with DAPI ...
• Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

  Hussam Husanie, et al., bioRxiv - Cancer Biology 2022

  Quote: ... monoclonal pSMAD 2/3 (Cell Signaling; 8828, Massachusetts, USA), monoclonal pSMAD 1/5/9 (Cell Signaling ...
• Ehrlichia Notch signaling induction promotes XIAP stability and inhibits apoptosis

  LaNisha L. Patterson, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit monoclonal α-Caspase-3 (9662S; Cell Signaling Technology), rabbit monoclonal α-Caspase-7 (9494S ...
• DiPRO1 dependent transcriptional and epigenetic regulation distinctly controls the fate of muscle and mesenchymal cancer cells

  Jeremy Rich, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit polyclonal cleaved Caspase-3 (Asp175) (Cell Signaling, 9661), anti-FLAG M2 affinity gel (Sigma-Aldrich ...
• The host-directed therapeutic imatinib mesylate accelerates immune responses to Mycobacterium marinum infection and limits pathology associated with granulomas

  Tesia L. Cleverley, et al., bioRxiv - Immunology 2022

  Quote: ... Cleaved Caspase 3 (ASP175) antibody (1:1000, Cell Signaling) and GAPDH (D16H11 ...
• Targeting DNA2 Overcomes Metabolic Reprogramming in Multiple Myeloma

  Natthakan Thongon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-human cleaved caspase 3 (D3E9, Cell Signaling).
• N-MYC regulates Cell Survival via eIF4G1 in inv(16) Acute Myeloid Leukemia

  Philomina Sona Peramangalam, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cleaved Caspase-3 (Asp175) Antibody (Cell signaling Technology, #9661), Cleaved PARP (Asp214 ...
• APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia

  Michael S. Haney, et al., bioRxiv - Neuroscience 2023

  Quote: ... and Caspase-3 (9661, Cell Signaling Technology, 1:500). The secondary antibodies were IgG conjugated to Alexa Fluor 488 (donkey anti-mouse ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cleaved Caspase-3 (1:1,000; Cell Signaling Technology #9664), and α-actin (1:5,000 ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cleaved Caspase-3 (1:200; Cell Signaling Technology #9664), Ser473-pAKT (1:500 ...