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401 - 450 of 10000+ citations for 1 5 Bromo 1 2 Trimethylsilyl Ethoxy Methyl 1H Pyrrolo 2 3 B Pyridin 3 Yl Ethanone since 2020

• An adapted stem cell-derived microglia protocol for the study of microgliopathies and other neurological disorders

  Marie-France Dorion, et al., bioRxiv - Neuroscience 2023

  Quote: ... NLR family pyrin domain containing 3 (NLRP3; 1:500; #15101S, Cell Signaling) and GAPDH (1:5000 ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Caspase-3 antibody (1:1,000 dilution, 9662, Cell Signaling Technology), rabbit anti-Cleaved Caspase-3 monoclonal antibody (1:1,000 dilution ...
• Talin regulates steady-state tensional homeostasis to drive vascular morphodynamics and cancer

  Pinelopi Nikolopoulou, et al., bioRxiv - Cell Biology 2022

  Quote: ... Cleaved Caspase-3 (1:300 dilution, Rabbit monoclonal; Cell Signaling, Cat# 9664), PECAM (1:400 dilution ...
• Talin regulates steady-state tensional homeostasis to drive vascular morphodynamics and cancer

  Pinelopi Nikolopoulou, et al., bioRxiv - Cell Biology 2022

  Quote: ... cleaved Caspase-3 (1:100 dilution, Rabbit monoclonal; Cell Signaling, Cat# 9664), YAP (1:100 dilution ...
• Functional characterization of cardiac fibroblasts in response to hemodynamic alteration

  Manabu Shiraishi, Ken Suzuki, Atsushi Yamaguchi, bioRxiv - Molecular Biology 2022

  Quote: ... anti-cleaved caspase 3 Ab at 1:100 dilution (9661, Cell Signaling), anti-αSMA Ab at 1:00 dilution (ab5694 ...
• Role of the NO-GC/cGMP signaling pathway in platelet biomechanics

  Johanna G. Rodríguez, et al., bioRxiv - Biochemistry 2023

  Quote: ... glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (rabbit, 1:1000, 14C10, Cell Signaling #2118S), NO-GC (sGC β1 ...
• RhoB promotes Salmonella survival by regulating autophagy

  Marco Kirchenwitz, et al., bioRxiv - Cell Biology 2023

  Quote: ... cleaved-caspase-3 (9661, 1:1000 dilution, RRID: AB_2341188, Cell Signaling Technology), AKT (9272 ...
• Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster

  Siddarth Gunnala, et al., bioRxiv - Neuroscience 2024

  Quote: ... The active caspase-3 primary antibody (ac3; 1:100, Cell Signaling Technologies, Danvers ...
• Loss of H3K9 trimethylation leads to premature aging

  Calida Mrabti, et al., bioRxiv - Physiology 2024

  Quote: ... NEL105001EA).Antibodies: mouse OCT-3/4 (C-10) (1:3000, Cell Signaling, 13969); mouse β-Actin (AC-74 ...
• Break-induced replication drives large-scale genomic amplifications in cancer cells

  Mouadh Benamar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mono-methyl Histone H4 (K20) (1:500, #9724; Cell Signaling), di-methyl Histone H4 (K20 ...
• Break-induced replication drives large-scale genomic amplifications in cancer cells

  Mouadh Benamar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Tri-methyl Histone H4 (K20) (1:500, #5737; Cell Signaling), DNA-PKcs (1:1000 ...
• Break-induced replication drives large-scale genomic amplifications in cancer cells

  Mouadh Benamar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... di-methyl Histone H4 (K20) (1:500, #9759; Cell Signaling), Tri-methyl Histone H4 (K20 ...
• MAPK Pathway Inhibition as A Rational Therapeutic Strategy for MiR-138-5p/PAQR3 Dysregulation-mediated Epirubicin Resistance in Triple-negative Breast Cancer

  Jianbo Huang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (#9102, Rabbit, WB 1:1000) and MEK1/2 (#4694, Mouse, WB 1:1000) antibodies were purchased from Cell Signaling Technology, MA ...
• Radiation-Induced Changes in Energy Metabolism Result in Mitochondrial Dysfunction in Salivary Glands

  Lauren G. Buss, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and anti-extracellular signal-regulated protein kinases 1/2 (ERK1/2) (p44/42 MAPK, Cell Signaling). For detection ...
• TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

  Engin Demirdizen, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-Tensin-2 (Cell Signaling #11990, 1:1000); rabbit anti-FAK (Cell Signaling #3285 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (Thr202/Tyr204) (1:500 Cell Signaling Technology), phospho-eEF2 (Thr56 ...
• Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

  Jill E. Hunter, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK 1/2 (phospho T202, Y204) (9101 Cell Signaling), ERK 1/2 (9102 Cell Signaling) ...
• HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness in Medulloblastoma

  Mariane da Cunha Jaeger, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p44/42 MAPK (Erk1/2, 1:1000; Cell Signaling) and β-actin (1:2000 ...
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p-ERK1/2 (Cell Signaling Technology, 4370, 1:2000), periostin (Invitrogen ...
• Wnt-dependent activation of ERK mediates repression of chondrocyte fate during calvarial development

  Beatriz Ibarra, Cody Machen, Radhika P. Atit, bioRxiv - Developmental Biology 2021

  Quote: ... rabbit-anti-Erk1/2 (1:500, Cell Signaling 9102), rabbit-anti-Lef1 (1:500 ...
• Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

  Amanda M. Rampersaud, et al., bioRxiv - Developmental Biology 2020

  Quote: ... phosphorylated ERK1/2 (E10, 1:2000, Cell Signaling Technology), focal adhesion kinase (FAK ...
• The neocortical progenitor specification program is established through combined modulation of SHH and FGF signaling

  Odessa R. Yabut, et al., bioRxiv - Developmental Biology 2020

  Quote: ... phosphor-Erk1/2 (1:100 dilution, Cell Signaling (#4370)) ...
• The Peroxiredoxin 6 gene plays a critical role in the homeostatic regulation of fear response

  Sarayut Phasuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-pERK1/2 (1:1000; Cell Signaling, Danvers, MA), anti-total ERK1/2 (1:1000 ...
• MEKK3-TGFβ crosstalk regulates inward arterial remodeling

  Hanqiang Deng, et al., bioRxiv - Pathology 2021

  Quote: ... p-ERK1/2 (Cell Signaling 4370; IB 1:1000).
• Protective mitochondrial fission induced by stress responsive protein GJA1-20k

  Daisuke Shimura, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-MEK1/2 (1:1000, Cell Signaling Technology). After overnight primary antibody incubation at 4 °C ...
• Defective mitochondrial-lysosomal axis promotes extracellular vesicles release of mitochondrial components in Huntington’s Disease

  Margarida Beatriz, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-flotillin-2 (C42A3) (1:500, #3436,Cell Signaling), anti-calnexin (1:500 ...
• Collagen-VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche

  Vasileios Papalazarou, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-ERK1/2 (1:1000; 9102, Cell Signaling Technology), anti-GAPDH (1:1000 ...
• Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs

  Antonio Cuevas-Navarro, et al., bioRxiv - Genetics 2022

  Quote: ... MEK1/2 (Cell Signaling Technologies, Cat #4694; 1:1000).
• Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs

  Antonio Cuevas-Navarro, et al., bioRxiv - Genetics 2022

  Quote: ... ERK1/2 (Cell Signaling Technologies, Cat #4696; 1:2000), p-MEK (Cell Signaling Technologies ...
• Optimized transcriptional signature for evaluation of MEK/ERK pathway baseline activity and long-term modulations in ovarian cancer

  Mikhail S. Chesnokov, Anil Yadav, Ilana Chefetz, bioRxiv - Cancer Biology 2022

  Quote: ... total ERK1/2 (Cell Signaling Technology, 137F5, 1:1000), pp90RSK1 (R&D Systems ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling technology; #4695, 1:1,000), anti-active β-Catenin (Cell signaling technology ...
• Nicotinamide mononucleotide treatment increases NAD+ levels in an iPSC Model of Parkinson’s Disease

  Brett K. Fulleylove-Krause, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-SIRT 2 (Cell Signaling, 12672, 1:1000), rabbit anti-SIRT 3 (Abgent ...
• Presenilin-deficient neurons and astrocytes display normal mitochondrial phenotypes

  Sabrina Contino, et al., bioRxiv - Neuroscience 2020

  Quote: ... Anti-Presenilin 2 (1:1,000; Cell Signaling, Danvers, USA); Anti-Tubulin (1:3000 ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling 4695, 1:2000), rabbit anti-phospho-PAK1 (S199/S204 ...
• Exploiting KRAS-driven Ferroaddiction in Cancer Through Ferrous Iron-Activatable Drug Conjugates (FeADC)

  Honglin Jiang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Erk1/2 (Cell Signaling Technology, 4696, Dilution: 1:1000); GAPDH (Cell Signaling Technology ...
• Rewiring of the TCR signalosome in natural intestinal Intraepithelial T lymphocytes drives non-deletional tolerance

  Harriet J. Watt, et al., bioRxiv - Immunology 2023

  Quote: ... SHP-1 or SHP-2 (all Cell Signaling Technology) followed by anti-rabbit Dylight649 (1:500 ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... ERK1/2 (1:1000, Cell Signaling Technology, Cat# 9102), phospho-p38 (Thr180/Tyr182 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... ERK1/2 (1:1000; 9102; Cell Signaling Technology, Inc.); phospho-AKT (Ser473 ...
• Neural stem cells protect blood-brain barrier integrity via the p38, JNK, and ERK1/2 pathways following intracerebral hemorrhage in rats

  Jing Sun, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-ERK1/2 (Cell Signaling, USA, 1:1000 dilution), anti-p38 (Cell Signaling ...
• Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis

  Abir Mukherjee, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HK-2 (Cell Signaling Technology, cat# 2867, 1:1000), p-STAT3 Tyr 708 (Cell Signaling Technology ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... phospho-ERK1/2 (1:200; 4370; Cell Signaling Technology), phospho-AKT (1:8,000 ...
• Competitive, connective and allosteric Nanobodies that modulate the SOS1•RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design

  Baptiste Fischer, et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit monoclonal ERK1/2 (1:50, Cell Signaling #4696), and mouse monoclonal Flag antibody (clone M2 ...
• Peripheral extracellular vesicle-derived miR-150-3p exacerbates acute kidney injury following acute pancreatitis by promoting ferroptosis through FTH1 signaling

  Ji-tao Cui, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Cox-2 (1:1,000, 9461, Cell Signaling Technology), anti-β-actin (1:2,000 ...
• Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation

  Eun Hye Park, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERK1/2 (Cell Signaling Technology, Cat.No.9102S, 1:1000), phospho-4EBP1 (Cell Signaling Technology ...
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  Tiantian Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Mek1/2 (1:1,000, Cell Signaling Technology, Cat# 9122), alpha-tubulin (Sigma ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-MAPKAPK-2 (1:1000, Cell Signaling 3042), rabbit anti-phospho-MAPKAPK-2 (Thr222 ...
• Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

  Lorenz Waltl, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-MEK1/2 (1:1000; # 9122; Cell Signaling), rabbit anti-phospho-MEK1/2 (1:1000 ...
• Multifunctional molecular hybrid for targeted colorectal cancer cells: Integrating doxorubicin, AS1411 aptamer, and T9/U4 ASO

  Kanpitcha Jiramitmongkon, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Bcl–2 (1:1000; 25 – 28 kDa, Cell signaling), and Bax (1:1000 ...
• Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression

  Nathaniel Shannon, et al., bioRxiv - Cell Biology 2024

  Quote: ... total MEK1/2 (1:1000, Cell Signaling Technology #9122), Cofilin (1:1000 ...
• The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

  Patience O. Obi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-Bcl-2 (3498, Cell Signaling, 1:1000), rabbit anti-Bax (2772 ...