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4201 - 4250 of 10000+ citations for Muscarinic Toxin 1 since 2019

• Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development

  Kenjiroo Matsumoto, et al., bioRxiv - Biochemistry 2024

  Quote: ... human N1 ICD (1/1000, #D1E11, Cell Signaling), Tubulin (1/5000 ...
• Proteomics-based characterization of ribosome heterogeneity in adult mouse organs

  Marie R Brunchault, et al., bioRxiv - Biochemistry 2024

  Quote: ... anti-RPS6 (1:5000, Rabbit, Cell Signaling 2217), anti-H3 (1:10 000 ...
• The host-directed therapeutic imatinib mesylate accelerates immune responses to Mycobacterium marinum infection and limits pathology associated with granulomas

  Tesia L. Cleverley, et al., bioRxiv - Immunology 2022

  Quote: ... and GAPDH (D16H11) antibody (1:1000, Cell Signaling) were used sequentially on the same membrane to quantify and normalize protein content.
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-GAPDH (1:5,000, #2188, Cell signaling technology), anti-HA (1:1,000 ...
• Skeletal Muscle Proteostasis Promotes Central Nervous System Function and Reduces Neuroinflammation during Aging and Neurodegenerative Disease

  Ian Matthews, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-LC3 antibody (Cell Signaling, 2775S, 1:1000) or anti-GAPDH (Invitrogen ...
• Innate immune receptor C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy in tumours with immunosuppressive microenvironments

  Callum Beach, et al., bioRxiv - Cancer Biology 2023

  Quote: ... RelA/p65 (Cell Signaling #3034, concentration 1:1000), pRelA/p65-S536 (Cell Signaling #3033T ...
• Drosophila FMRP recruits the miRISC to target mRNAs to repress translation

  Navneeta Kaul, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HA (dilution 1:500; Cell Signaling Technology #2367), FLAG (dilution 1:1000 ...
• Sonic Hedgehog Activates Prostaglandin Signaling to Stabilize Primary Cilium Length

  Shariq S. Ansari, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-acetylated α-tubulin (Cell Signaling, 1:1000), anti-ARL13B (Antibodies Incorporated ...
• Deletion of transglutaminase 2 from astrocytes significantly improves their ability to promote neurite outgrowth on an inhibitory matrix

  Jacen Emerson, et al., bioRxiv - Neuroscience 2023

  Quote: ... MAP2 primary antibody (1:200) (Cell Signaling #8707S) was diluted in blocking buffer and incubated overnight on the coverslips ...
• Aged Breast Matrix Bound Vesicles Promote Breast Cancer Invasiveness

  Jun Yang, et al., bioRxiv - Bioengineering 2023

  Quote: ... or Adiponectin antibody (Cell Signaling Technology,1:200) for 48 hours ...
• TGFB1 Induces Fetal Reprogramming and Enhances Intestinal Regeneration

  Lei Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... p-SMAD2/3 (Cell signaling 8828, 1:1000), SMAD2/3 (Cell signaling 8685 ...
• OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

  Mariarosaria De Rosa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... pCHK2 T68 (Cell Signaling 2197; 1:1000 WB), pCHK1 S345 (Cell Signaling 2348 ...
• OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

  Mariarosaria De Rosa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... pCHK1 S345 (Cell Signaling 2348; 1:500 WB), pATM S 1981 (Abcam ab81292 ...
• Melatonin alleviates LPS-induced abnormal pregnancy through MTNR1B regulation of m6A

  Shisu Zhao, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-MTNR1B (1:100, Cell Signaling Technology, USA). Then ...
• Noncanonical Rab9a action supports endosomal exit of human papillomavirus during virus entry

  Jeongjoon Choi, Daniel DiMaio, bioRxiv - Microbiology 2023

  Quote: ... pan actin (Cell Signaling Technology, 4968, 1:2,000), FLAG (Sigma ...
• NF-κB c-REL-OTUD4 axis regulates B-cell receptor in B-cell lymphoma

  Eslam Katab, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD79B (1:1000, rabbit, Cell Signaling Technology #96024), FLAG (1:1,000 ...
• VRK3 depletion induces cell cycle arrest and metabolic reprogramming of Pontine Diffuse Midline Glioma (DMG)-K27 altered cells

  Virginie Menez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-Phalloidine (1/200 #8940S, Cell signaling) and 45 minutes with secondary antibodies (Alexa fluor ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Amyloid-β (1:100; Cell Signaling, 8243), anti-Amyloid-β (1-42 ...
• Phosphorylation of pyruvate dehydrogenase marks the inhibition of in vivo neuronal activity

  Dong Yang, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Orexin (1:100, Cell Signaling #16743), rabbit anti-MCH (1:200 ...
• Targeting the Cx26/NANOG/Focal Adhesion Kinase Complex via Cell-Penetrating Peptides in Triple-Negative Breast Cancers

  Erin E. Mulkearns-Hubert, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-FAK (D2R2E) (Cell Signaling #13009; 1:1000), anti-Lamin A/C (Proteintech #10298-1-AP ...
• Impaired migration and premature differentiation underlie the neurological phenotype associated with PCDH12 loss of function

  Jennifer Rakotomamonjy, et al., bioRxiv - Neuroscience 2023

  Quote: ... alpha-Tubulin (1:1000, Cell Signaling Technology, 2144), N-cadherin (1:1000 ...
• Impaired migration and premature differentiation underlie the neurological phenotype associated with PCDH12 loss of function

  Jennifer Rakotomamonjy, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1:100 phospho-Vimentin (Cell Signaling Technology, 3877S), 1:500 phospho-Histone H3 (Abcam ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... p-eif2α (S51, Cell Signaling, 119A11, 1:1000), eif2α (total ...
• Prostaglandin E₂ controls the metabolic adaptation of T cells to the intestinal microenvironment

  Matteo Villa, et al., bioRxiv - Immunology 2023

  Quote: ... anti-ATG5 (clone D5F5U, 1:1,000, Cell Signaling), anti-Gclc (clone OTI1A3 ...
• Cell migration CRISPRi screens in human neutrophils reveal regulators of context-dependent migration and differentiation state

  Nathan M. Belliveau, et al., bioRxiv - Cell Biology 2022

  Quote: ... p-Ser473 Akt (1:2000; Cell Signaling, #4060), total mTOR (1:1000 ...
• Tumour Extracellular Vesicles Induce Neutrophil Extracellular Traps To Promote Lymph Node Metastasis

  Xin Su, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-Rab27a (1:500, 69295; Cell Signaling).
• An Innovative Non-Hormonal Strategy Targeting Redox Active Metals to Down-Regulate Estrogen-, Progesterone-, Androgen- and Prolactin-Receptors in Breast Cancer

  Faten Shehadeh-Tout, et al., bioRxiv - Cancer Biology 2023

  Quote: ... AR (1:300; Cat #: 5153; Cell Signaling Technology), and PR (1:700 ...
• Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A

  Stefan Harjes, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-HA (#3724S, 1:2500, Cell Signaling), and rabbit anti-Cas9 (#ab189380 ...
• Insulin-mediated endothelin signaling is antiviral during West Nile virus infection

  Chasity E. Trammell, et al., bioRxiv - Microbiology 2023

  Quote: ... anti-Akt (pan) (1:2,000) (Cell Signaling 4691), or anti-actin (1:10,000 ...
• PD1 is transcriptionally regulated by LEF1 in mature T cells

  Pin Zhao, Lanming Sun, Cong Zhao, Samiullah Malik, bioRxiv - Immunology 2023

  Quote: ... LEF1 (Dilution of 1:5000, C12A5, Cell Signaling); β-actin (Dilution of 1:2000 ...
• Oropouche virus glycoprotein topology and cellular requirements for virus assembly

  Natalia S. Barbosa, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-HA (Cell Signaling Technology C29F4, 1:20,000), anti-actin (Sigma A3853 ...
• DiPRO1 dependent transcriptional and epigenetic regulation distinctly controls the fate of muscle and mesenchymal cancer cells

  Jeremy Rich, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-cleaved caspase 3 (1/100) (Cell Signaling), visualized using the polink anti rat kit (GBI Labs ...
• RHINO restricts MMEJ activity to mitosis

  Alessandra Brambati, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HUS1 (D4J9H, Cell Signaling Technology; 1: 1000 dilution), Polθ (gift from Repare therapeutics ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... phospho-AKT S473 (Cell Signaling, #4060, 1:1000), c-Raf (Cell Signaling ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... phospho-AKT T308 (Cell Signaling, #2965, 1:1000), phospho-AKT S473 (Cell Signaling ...
• Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models

  Luana Naia, et al., bioRxiv - Neuroscience 2023

  Quote: ... ULK1 (1:500) (Cell signaling, Cat. no. 8054), pSer555-ULK1 (1:500 ...
• Long-read sequencing and profiling of RNA-binding proteins reveals the pathogenic mechanism of aberrant splicing of an SCN1A poison exon in epilepsy

  Hannah C Happ, et al., bioRxiv - Genetics 2023

  Quote: ... Beta-actin (1:1000, Cell Signaling Technologies #3700S) was also used as additional sample loading control ...
• SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

  Brianna R. Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-MEK1/2 (Cell Signaling 4694; 1:1000), anti-pRSK (Cell Signaling 9344 ...
• SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

  Brianna R. Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-ERK1/2 (Cell Signaling 4696; 1:1000), anti-pAKT Ser473 (Cell Signaling 4060 ...
• SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

  Brianna R. Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-pAKT Ser473 (Cell Signaling 4060; 1:1000), anti-AKT (Cell Signaling 2920 ...
• SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

  Brianna R. Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-pERK1/2 (Cell Signaling 4370; 1:1,000), anti-ERK1/2 (Cell Signaling 4696 ...
• SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

  Brianna R. Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-pMEK1/2 (Cell Signaling 9154; 1:1000), anti-MEK1/2 (Cell Signaling 4694 ...
• SOS2 regulates the threshold of mutant EGFR-dependent oncogenesis

  Patricia L. Theard, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-ERK1/2 (Cell Signaling 4696; 1:1000), anti-pAKT Ser473 [Cell Signaling 4060 ...
• SOS2 regulates the threshold of mutant EGFR-dependent oncogenesis

  Patricia L. Theard, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and E-Cadherin (Cell Signaling 14472; 1:1000) primary antibodies ...
• SOS2 regulates the threshold of mutant EGFR-dependent oncogenesis

  Patricia L. Theard, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-pERK1/2 (Cell Signaling 4370; 1:1,000), anti-ERK1/2 (Cell Signaling 4696 ...
• FMRP-Regulated Alternative Splicing is Multifactorial and Resembles Splicing Control by MBNL1

  Suna Jung, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-MBNL1 (Cell signaling technology, 94633, 1:1,000), anti-MBNL2 (Cell signaling technology ...
• FMRP-Regulated Alternative Splicing is Multifactorial and Resembles Splicing Control by MBNL1

  Suna Jung, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-PTBP2 (Cell signaling technology, 59753, 1:1,000), anti-hnRNPF (Novusbio ...
• FMRP-Regulated Alternative Splicing is Multifactorial and Resembles Splicing Control by MBNL1

  Suna Jung, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-PTBP1 (Cell signaling technology, 57246, 1:1,000), anti-PTBP2 (Cell signaling technology ...
• ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion

  Demis Menolfi, et al., bioRxiv - Genetics 2023

  Quote: ... pCHK1 Ser245 (1:1000, 133D3 Cell Signaling, #2348), CHK1 (1:1000 ...
• ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion

  Demis Menolfi, et al., bioRxiv - Genetics 2023

  Quote: ... KAP1 (1:1000, TIF1β, C42G12 Cell Signaling, #4124), pCHK1 Ser245 (1:1000 ...