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3801 - 3850 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HSPB1 (1/1000, Cell Signaling Technologies, #95357), Histone H3 (1/1000 ...
• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HSPB1 (1/400, Cell Signaling Technologies, #95357), and HSPB1 (2 ug/ml ...
• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Akt (1/1000, Cell Signaling Technologies, #4691T), p-Akt(ser473 ...
• Cell fusion upregulates PD-L1 expression and promotes tumor formation

  Youichi Tajima, Futoshi Shibasaki, Hisao Masai, bioRxiv - Cancer Biology 2022

  Quote: ... Cell Signaling Technology),anti-IRF-1 (#8478, Cell Signaling Technology), anti-Jak1 (#3344 ...
• Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model

  Mariah L. Hoye, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-CC3 (Cell Signaling, 9661, 1:250), anti-NEUROD2 (Abcam ...
• High-throughput Oligopaint screen identifies druggable regulators of genome folding

  Daniel S. Park, et al., bioRxiv - Genetics 2022

  Quote: ... GSK3A (Cell Signaling Technology 4337, 1:50), GSK3B (BD Biosciences 610201 ...
• cGAS/STING-DEPENDENT SENSING OF ENDOGENOUS RNA

  Tina Schumann, et al., bioRxiv - Immunology 2022

  Quote: ... β-actin (Cell Signaling Technology, #4970, 1:10.000) and Cyclophilin B (Cell Signaling Technology ...
• High-throughput Oligopaint screen identifies druggable regulators of genome folding

  Daniel S. Park, et al., bioRxiv - Genetics 2022

  Quote: ... HDAC2 (Cell Signaling Technology 5113, 1:1000), H3 (Abcam 1791 ...
• HAPLN1 is a driver for peritoneal carcinomatosis in pancreatic cancer

  Lena Wiedmann, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-pSTAT3 (1:200, Cell Signaling, #9145), anti-CD45 (1:50 ...
• Nuclear receptor interaction protein (NRIP) as a novel actin-binding protein involved in invadosome formation for myoblast fusion

  Hsin-Hsiung Chen, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-EGF receptor (Cell Signaling, 1:1000), anti-DsRed (TaKaRa ...
• A therapeutically targetable NOTCH1-SIRT1-KAT7 axis in T-cell Leukemia

  Olga Lancho, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-AMPK (1:1000, 5831S, Cell Signaling), anti-p-AMPK (1:1000 ...
• A therapeutically targetable NOTCH1-SIRT1-KAT7 axis in T-cell Leukemia

  Olga Lancho, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-p53 (1:1000, 2524S, Cell Signaling), anti-ac-p53 (1:1000 ...
• A therapeutically targetable NOTCH1-SIRT1-KAT7 axis in T-cell Leukemia

  Olga Lancho, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-GAPDH (1:10000, 97166, Cell Signaling) and anti-β-actin-HRP (1:50000 ...
• Disruption of integrin alpha-5/beta-1-dependent transforming growth factor beta-1 signaling pathway attenuates vessel co-option in colorectal cancer liver metastases

  Miran Rada, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and ITGβ1 1:200 (Cell Signaling, #9699).
• The molecular organization of flat and curved caveolae indicates bendable structural units at the plasma membrane

  Claudia Matthaeus, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-GAPDH-Rabbit (Cell Signaling, 1:1000), anti-mouse-HRP (dianova ...
• Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

  Josef Leibold, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and Vimentin (1:200, Cell Signaling, 5741).
• HCP5 prevents ubiquitination-mediated UTP3 degradation to inhibit apoptosis by activating c-Myc transcriptional activity

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ubiquitin (1:1000, Cell Signaling Technology, #3936), H3 (1:10000 ...
• HCP5 prevents ubiquitination-mediated UTP3 degradation to inhibit apoptosis by activating c-Myc transcriptional activity

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... TRIM29 (1:1000, Cell Signaling Technology, #5182), VAMP3 (1:2000 ...
• Non-cancer stem cell-derived Fibromodulin activates Integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth

  Shreoshi Sengupta, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pFAK (Cell Signaling Technology #3283S, 1:500), GAPDH (Sigma #G8795 ...
• Non-cancer stem cell-derived Fibromodulin activates Integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth

  Shreoshi Sengupta, et al., bioRxiv - Cancer Biology 2022

  Quote: ... FAK (Cell Signaling Technology 3285S, 1:1000), pFAK (Cell Signaling Technology #3283S ...
• A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives glioblastoma progression

  Zhihong Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... in 1 x TBST (Cell Signaling, 9997) for 1 hour ...
• Substance P and adenosine signaling pathways regulate exosomal sorting of miR-21 in colonic epithelial cells

  Sameena Wani, et al., bioRxiv - Cell Biology 2022

  Quote: ... sCREB (1:1,000, 4820S; Cell signaling Technology), anti-p-CREB (1:1,000 ...
• Substrate trapping approach identifies TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes

  Emily Yang, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1:1000 anti-UPF1 (Cell Signaling Technology), 1:10,000 anti-NME1 (Abcam) ...
• Defining the Ligand-dependent Interactome of the Sigma 1 Receptor

  Jing Zhao, et al., bioRxiv - Cell Biology 2022

  Quote: ... Calnexin (Cell Signaling; 1:1000 for western); Sec61alpha (Santa Cruz ...
• Targeting tau mitigates mitochondrial fragmentation and oxidative stress in amyotrophic lateral sclerosis

  Tiziana Petrozziello, et al., bioRxiv - Neuroscience 2021

  Quote: ... pDRP1-S616 (1:500, Cell Signaling, MA), Mfn1 (1:500 ...
• Targeting tau mitigates mitochondrial fragmentation and oxidative stress in amyotrophic lateral sclerosis

  Tiziana Petrozziello, et al., bioRxiv - Neuroscience 2021

  Quote: ... PSD-95 (1:500; Cell Signaling, MA), GADPH (1:1000 ...
• Targeting Gys1 with AAV‐SaCas9 decreases pathogenic polyglucosan bodies and neuroinflammation in Adult Polyglucosan Body and Lafora disease mouse models

  Emrah Gumusgoz, et al., bioRxiv - Neuroscience 2021

  Quote: ... and for GYS1 (1:1000, Cell Signaling) were used ...
• YAP/TAZ Maintain the Proliferative Capacity and Structural Organization of Radial Glial Cells During Brain Development

  Alfonso Lavado, et al., bioRxiv - Developmental Biology 2021

  Quote: ... YAP/TAZ (Cell Signaling #4912, 1:500), and GAPDH (Cell Signaling #2118 ...
• YAP/TAZ Maintain the Proliferative Capacity and Structural Organization of Radial Glial Cells During Brain Development

  Alfonso Lavado, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and GAPDH (Cell Signaling #2118, 1:5000).
• Insights into calcium signaling and gene expression in astrocytes uncovered with 129S4 Slc1a3-2A-CreERT2 knock-in mice

  Lech Kaczmarczyk, et al., bioRxiv - Neuroscience 2020

  Quote: ... RPL26 1:100 (Cell Signaling, RRID: AB_10698750). Secondary antibodies (each used at 1:500) ...
• Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma

  Chun-Chun Cheng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... COXIV (1:200, 4850, Cell Signaling Technology). Staining was quantitated using ImageJ software.
• Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma

  Chun-Chun Cheng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... PARP (1:1000, 9532, Cell Signaling Technology), ERK (1:3000 ...
• Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma

  Chun-Chun Cheng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... COXIV (1:5000, 4850, Cell Signaling Technology), β-Actin (1:10,000 ...
• The Drosophila FUS ortholog cabeza promotes adult founder myoblast selection by Xrp1-dependent regulation of FGF signaling

  Marica Catinozzi, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and Phalloidin-647 (1:20; Cell Signaling) were applied for 3 h at RT.
• H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion by activating TRNP1 expression

  Cemil Kerimoglu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... CASP3 rabbit pAb (1:100; Cell Signaling), CTIP2 rat pAb (1:200 ...
• Transmission-selective muscle pathology induced by active propagation of mutant huntingtin across the human neuromuscular synapse

  Dinamarca C. Margarita, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1:2000 Doublecortin (DC) (4604, Cell signaling), 1:1000 Choline acetyltransferase (ChAT ...
• Kin17 drives dissociation of Mira from the centrosome in neuroblasts by regulating splicing of Flfl

  Marisa Connell, Yonggong Xie, Rui Chen, Sijun Zhu, bioRxiv - Cell Biology 2021

  Quote: ... PH3 (Ms; Cell Signaling Technology; 1:1000); Elav (Rat (Rt) ...
• Growth of tumor emboli within a vessel model reveals dependence on the magnitude of mechanical constraint

  Jonathan Kulwatno, et al., bioRxiv - Cell Biology 2020

  Quote: ... and GAPDH (1:15000; Cell Signaling Technology) were diluted in TBST-5% BSA ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... STAT2 (1:1,000, 4594S, Cell Signaling Technology), IFNAR1 (1:1,000 ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... pSTAT2 (1:1,000, Y690, Cell Signaling Technology), STAT2 (1:1,000 ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... STAT1 (1:1,000, 9172S, Cell Signaling Technology), pSTAT2 (1:1,000 ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... Rab5 (1:1,000, C8B1, Cell Signaling Technology), SARS-CoV-2 Nsp3 (1:1,000 ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... pSTAT1 (1:1,000, Y701, Cell Signaling Technology), STAT1 (1:1,000 ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... ULK1 (1:1,000, D8H5, Cell Signaling Technology), Rab5 (1:1,000 ...
• Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells

  Allisson B. Justino, et al., bioRxiv - Biochemistry 2021

  Quote: ... vinculin (mouse, 1:1,000, Cell Signaling Technology), epidermal growth factor receptor EGFR (mouse ...
• Immunoproteasome deficiency leads to sustained pancreatic injury and delayed recovery from experimental pancreatitis

  Laura L. De Freitas Chama, et al., bioRxiv - Physiology 2020

  Quote: ... anti-CHOP (1:2000; 2895, Cell Signaling) and anti-LC3 (1:2000 ...
• ErbB dysregulation impairs cognition via myelination-dependent and - independent oligodendropathy

  Xu Hu, et al., bioRxiv - Neuroscience 2020

  Quote: ... Ki67 (1:400, Cell Signaling Technology, 9129), GFAP (1:2000 ...
• A chemical screen identifies a link between lipid metabolism and mRNA translation

  Alba Corman, et al., bioRxiv - Molecular Biology 2020

  Quote: ... P70S6K (1:1000, Cell Signaling Technology, 9202S), 4E-BP1 (1:1000 ...
• A chemical screen identifies a link between lipid metabolism and mRNA translation

  Alba Corman, et al., bioRxiv - Molecular Biology 2020

  Quote: ... eIF2a (1:500, Cell Signaling Technology, 9722), Vinculin (EPR8185 ...
• Inositol Polyphosphate-5-phosphatase K (Inpp5k) enhances sprouting of corticospinal tract axons after CNS trauma

  Sierra D. Kauer, et al., bioRxiv - Neuroscience 2021

  Quote: ... Phospho-Cofilin (Ser3) (1:250, Cell Signaling), and EB3 (1:250 ...