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3751 - 3800 of 10000+ citations for IL 1 Alpha Human since 2019

• The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release

  Lea Jabbour, et al., bioRxiv - Cell Biology 2021

  Quote: ... Cleaved Caspase 3 (Cell Signaling #9661, 1/1000) antibody was used to assess cell death followed by Alexa fluor 563 coupled secondary antibodies ...
• Proprotein Convertase Subtilisin/kexin Type 9 Links Inflammation to Vascular Endothelial Cell Dysfunction

  Thorsten M. Leucker, et al., bioRxiv - Cell Biology 2021

  Quote: ... GAPDH (D16H11, 1:2,000 dilution, Cell Signaling Technology).PVDF membranes were incubated overnight at 4C with primary antibodies diluted in 1X TBS Intercept Blocking Buffer (LiCor ...
• Differentiation of ciliated human midbrain-derived LUHMES neurons

  Gilbert Lauter, et al., bioRxiv - Neuroscience 2020

  Quote: ... PSD95 (DLG4) (rabbit, Cell Signaling 2507, 1:100), KIF17 (rabbit ...
• MitoROS due to loss of Slc4a11 in corneal endothelial cells induces ER stress, lysosomal dysfunction and impairs autophagy

  Rajalekshmy Shyam, et al., bioRxiv - Cell Biology 2020

  Quote: ... v-ATPase (1:1000, #14617S, Cell Signaling Technologies), TFEB (1:1000 ...
• MitoROS due to loss of Slc4a11 in corneal endothelial cells induces ER stress, lysosomal dysfunction and impairs autophagy

  Rajalekshmy Shyam, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cathepsin B (1:1000, #31718, Cell Signaling Technologies), β-actin (1:2000 ...
• Single cell atlas of beige remodeling of white adipose tissue reveals a myeloid to lymphoid shift during cold exposure compared to beta 3 adrenergic stimulation

  Nabil Rabhi, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-CD45 (D3F8Q; Cell Signaling, 1:100) overnight at 4C ...
• STUB1 is an intracellular checkpoint for interferon gamma sensing

  Simon Ng, et al., bioRxiv - Cancer Biology 2021

  Quote: ... STAT1 (Cell Signaling Technology, #14995, 1:10,000 dilution), phospho-Tyr701-STAT1 (Cell Signaling Technology ...
• STUB1 is an intracellular checkpoint for interferon gamma sensing

  Simon Ng, et al., bioRxiv - Cancer Biology 2021

  Quote: ... STAT2 (Cell Signaling Technology, #72604, 1:2000 dilution), IRF1 (Cell Signaling Technology ...
• STUB1 is an intracellular checkpoint for interferon gamma sensing

  Simon Ng, et al., bioRxiv - Cancer Biology 2021

  Quote: ... IRF1 (Cell Signaling Technology, #8478, 1:2000 dilution), PSMB8 (Cell Signaling Technology ...
• STUB1 is an intracellular checkpoint for interferon gamma sensing

  Simon Ng, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PSMB8 (Cell Signaling Technology, #13635, 1:2,000 dilution), PSMB9 (Abcam ...
• Transcriptional Control of Brain Tumour Stem Cells by a Carbohydrate Binding Protein

  Ahmad Sharanek, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-STAT3 (Tyr705) (1:1000, Cell Signaling, #9138), DLL1 (1:300 ...
• The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis

  Mara De Marco Zompit, et al., bioRxiv - Cell Biology 2021

  Quote: ... and CIP2A (Rabbit, 14805, Cell Signaling, 1/1000). Blots were developed with SuperSignal™ West Femto Maximum Sensitivity Substrate (Thermo Scientific™ ...
• Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology

  Markus Terrey, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-GAPDH (Cell Signaling, #2118, 1:10,000), rabbit anti-phospho-p70S6KT389 (Cell Signaling ...
• Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology

  Markus Terrey, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-eIF2α(Cell Signaling, #9722, 1:2000), rabbit anti-Hbs1l (Proteintech ...
• A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes corpus luteum regression

  Dianrong Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Caspase8 (#9746, Cell Signaling; WB, 1:1000), anti-FADD (#2782 ...
• A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes corpus luteum regression

  Dianrong Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-FADD (#2782, Cell Signaling; WB, 1:1000), anti-cFLIP (ab6144 ...
• A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes corpus luteum regression

  Dianrong Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-RIPK1 (#3493S, Cell Signaling; WB, 1:2000), anti-Human-MLKL (ab184718 ...
• Liver FoxO1 overexpression is positively associated with the degree of liver injury in cirrhotic patients

  Esther Fernandez-Galán, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-tubulin antibody (1:5000 Cell Signaling). Next ...
• Synaptojanin1 deficiency upregulates basal level autophagosome formation in astrocytes

  Ping-Yue Pan, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-Parkin (Cell signaling, 42115, 1:1000), rabbit anti-pS2481 mTOR (Cell signaling ...
• Synaptojanin1 deficiency upregulates basal level autophagosome formation in astrocytes

  Ping-Yue Pan, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-mTOR (Cell signaling, 2983, 1:1000), rabbit anti-pS757 ULK1 (Cell signaling ...
• Synaptojanin1 deficiency upregulates basal level autophagosome formation in astrocytes

  Ping-Yue Pan, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-ULK1 (Cell signaling, 6439, 1:1000), rabbit anti-pT172 AMPK (Cell signaling ...
• Synaptojanin1 deficiency upregulates basal level autophagosome formation in astrocytes

  Ping-Yue Pan, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-AMPKα (Cell signaling, 2532, 1:1000), rabbit anti-GLUT1 (Abcam ...
• Retrograde And Anterograde Transport Of LAT-Vesicles During The Immunological Synapse Formation: Defining The Finely-Tuned Mechanism

  Juan José Saez, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-CD28 (1:1000, 38774, Cell Signaling), rabbit anti-GMAP210 (Gift from Michel Bornens) ...
• Retrograde And Anterograde Transport Of LAT-Vesicles During The Immunological Synapse Formation: Defining The Finely-Tuned Mechanism

  Juan José Saez, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-PLCγl (1:1000, 2822S, Cell Signaling), rabbit anti-ZAP70 (1:1000 ...
• Retrograde And Anterograde Transport Of LAT-Vesicles During The Immunological Synapse Formation: Defining The Finely-Tuned Mechanism

  Juan José Saez, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ZAP70 (1:1000, 3165S, Cell Signaling), rabbit anti-LAT (5 μg/ml ...
• Circumventing drug treatment? Polyethylenimine functionalized nanoparticles inherently and selectively kill patient-derived glioblastoma stem cells

  Neeraj Prabhakar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... LC3-β (2775s) (1:1000) from Cell Signaling. Loading control antibodies for β-actin (sc-47778 ...
• Chitinase 3-like-1 Stimulates PD-L1 and Other Immune Checkpoint Inhibitors

  Bing Ma, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and PTEN (1:1000) (Cell signaling, Danvers, MA). After 48 hour incubation with test and control antibodies ...
• Cancer cells induce hepatocytes apoptosis in co-opted colorectal cancer liver metastatic lesions

  Miran Rada, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved caspase-3 1:500 (Cell signaling, # 9664S) and cleaved PARP-1 1:500 (Cell signaling ...
• SLIT2-ROBO signaling in tumor-associated microglia/macrophages drives glioblastoma immunosuppression and vascular dysmorphia

  Luiz Henrique Geraldo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-pPLCγ Ser 1248 (Cell Signaling, 1:1000), anti-PLCγ (4511T ...
• Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis

  Christopher Brereton, et al., bioRxiv - Cell Biology 2021

  Quote: ... active β-catenin (1:1000, Cell Signaling Technology). Immunodetected proteins were identified using the enhanced chemiluminescence system (Clarity Western Blotting ECL Substrate ...
• Triplet kinase-phosphatase targeting to overcome kinase inhibitor tolerance in brain tumor cells

  Oxana V. Denisova, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho Akt S473 (Cell Signaling, 9271, 1:1,000), PME-1 (Santa Cruz ...
• Native size exclusion chromatography-based mass spectrometry (SEC-MS) identifies novel components of the Heat Shock Protein 90-dependent proteome

  Rahul S. Samant, et al., bioRxiv - Biochemistry 2022

  Quote: ... Hop (#4464, 1:2,000) from Cell Signaling Technologies; and HSP70/HSP72 (ADI-SPA-810-D ...
• Discovery of a new class of reversible TEA-domain transcription factor inhibitors with a novel binding mode

  Lu Hu, et al., bioRxiv - Biochemistry 2022

  Quote: ... or anti-YAP (1:1000, 140745, Cell Signaling) antibody were used to detect TEAD1 ...
• Discovery of a new class of reversible TEA-domain transcription factor inhibitors with a novel binding mode

  Lu Hu, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-pan-TEAD (1:1000, 13295, Cell Signaling) or anti-YAP (1:1000 ...
• High salt induces cognitive impairment via the angiotensin II-AT1 and prostaglandin E2-EP1 systems

  Hisayoshi Kubota, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-PSD95 (1:1,000; Cell Signaling Technology), and mouse anti-β-actin (1:1,000 ...
• HCP5 prevents ubiquitination-mediated UTP3 degradation to inhibit apoptosis by activating c-Myc transcriptional activity

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... cleaved PARP (1:1000, Cell Signaling Technology, #5625), MCL1 (1:1000 ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... F4/80 (#70076, Cell Signaling Technology, 1:200). For immunohistochemistry ...
• The ITPRIPL1- CD3ε axis: a novel immune checkpoint controlling T cells activation

  Shouyan Deng, et al., bioRxiv - Immunology 2022

  Quote: ... and CD8α (Cat98941, 1:200; Cell Signaling Technology). After three times PBS washing ...
• Role of Yap1 in adult neural stem cell activation

  Wenqiang Fan, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Yap1 (1:200, Cell Signaling, 14074S), mouse anti-Yap1 (1:200 ...
• Re-routing metabolism by the mitochondrial pyruvate carrier inhibitor MSDC-0160 attenuates neurodegeneration in a rat model of Parkinson’s disease

  David Mallet, et al., bioRxiv - Neuroscience 2022

  Quote: ... acetyl-coenzyme A acetyltransferase 1 (Cell Signaling; s44276), carnitine palmitoyltransferase 1a (Cell Signaling ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti Smad3 (1:1000, #9513, Cell Signaling) and rabbits anti-phospho-PKA substrates (RRXS*/T* ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti Smad3 (1:250, #9513, Cell Signaling) and Sirt1 (1:250 ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... and anti-Smad3 (1:100, #9513, Cell Signaling) were used for immunoprecipitation as described above ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... Rabbit anti PCBP1 (1:150, #85341, Cell signaling) and rabbit anti Smad3 (1:100 ...
• Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

  Favio A. Krapacher, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti Smad3 (1:250, #9513, Cell Signaling), chicken anti MAP2 (1:5000 ...
• Aspirin Synergizes with Regorafenib to Reduce Growth of Colorectal Cancer

  Chang Su, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 1% Protease Inhibitor Cocktail (Cell Signaling Cat# 5871) and 1% Phosphatase Inhibitor Cocktail (Cell Signaling Cat# 5870) ...
• DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-H3K4me1 (5326, Cell Signaling Technology, 1:1000), anti-H3K27me3 (9733 ...
• Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment

  Mokryun L. Baek, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-VDAC (1:1000, Cell Signaling Technology, 4661S), anti-β-tubulin (1:1000 ...
• DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-H3K27ac (8173, Cell Signaling Technology, 1:1000), anti-H4K16ac (13534 ...
• Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment

  Mokryun L. Baek, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-DRP1 (1:1000, Cell Signaling Technology, 8570S), anti-DRP1(S616 ...