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3751 - 3800 of 10000+ citations for 6H Imidazo 4 5 e 2 1 3 benzothiadiazole 7 methyl 9CI since 2019

• Multiomics Analyses Reveal Dynamic Bioenergetic Pathways and Functional Remodeling of the Heart During Intermittent Fasting

  Thiruma V. Arumugam, et al., bioRxiv - Systems Biology 2023

  Quote: ... IRS-1 (2382S, Cell Signaling), and GAPDH (2118S ...
• Evolution of promoter-proximal pausing enabled a new layer of transcription control

  Alexandra G. Chivu, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... 1 mM PMSF (Cell Signaling), and cOmplete Ultra protease inhibitor (Sigma ...
• Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation

  Moises Freitas-Andrade, et al., bioRxiv - Developmental Biology 2023

  Quote: ... -Pou3f2 (1:200, Cell Signaling), -Ki67 (1:250 ...
• Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

  Maiko Matsui, et al., bioRxiv - Physiology 2023

  Quote: ... AMPK (1:1000, Cell Signaling), pAMPK (1:1000 ...
• Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

  Maiko Matsui, et al., bioRxiv - Physiology 2023

  Quote: ... pAMPK (1:1000, Cell Signaling), Vinculin ...
• Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors

  Anderson R Frank, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:2,000 (Cell Signaling 2017); anti-LDHA ...
• Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome

  Suchira Gallage, et al., bioRxiv - Physiology 2023

  Quote: ... 1:200 (Cell Signaling, #3177); anti-MHCIl ...
• Loss of Wdr23 drives neuronal mitochondrial biogenesis

  Ronald Irwin, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GCLC (Cell signaling, 1:1000), RXFP3 (Novus Biologicals ...
• Serine arginine-rich splicing factor (SRSF7) cooperates with the histone methyltransferase KMT5a to promote the type I interferon response via transcriptional activation of IRF7

  Haley M. Scott, et al., bioRxiv - Immunology 2023

  Quote: ... STAT1 (Cell Signaling, 1:1000), IRF7 (Cell Signaling ...
• WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus

  Jiahui Liu, et al., bioRxiv - Molecular Biology 2023

  Quote: ... SOD2 (Cell signaling, 1:1000), G6PD (Proteintech ...
• Tweek-dependent formation of ER-PM contact sites enables astrocyte phagocytic function and remodeling of neurons

  Yunsik Kang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Actin (1:1000 Cell Signaling) and Brp (1:1000 DSHB).
• Serine arginine-rich splicing factor (SRSF7) cooperates with the histone methyltransferase KMT5a to promote the type I interferon response via transcriptional activation of IRF7

  Haley M. Scott, et al., bioRxiv - Immunology 2023

  Quote: ... IRF7 (Cell Signaling, 1:1000), SRSF7 (Bethyl 1:3000 ...
• Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome

  Suchira Gallage, et al., bioRxiv - Physiology 2023

  Quote: ... 1:100 (Cell Signaling, #5544); anti-BiP ...
• The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection

  Marcus P. Wong, et al., bioRxiv - Immunology 2023

  Quote: ... 1:500 (Cell Signaling, 63660), α-mouse Caspase-1 (p20 ...
• The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection

  Marcus P. Wong, et al., bioRxiv - Immunology 2023

  Quote: ... 1:1000 (Cell Signaling, D4D8T); rabbit-α-mouse AIM2 ...
• Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors

  Anderson R Frank, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:5,000 (Cell Signaling 2965).
• S-Nitrosylation of CRTC1 in Alzheimer’s disease impairs CREB-dependent gene expression induced by neuronal activity

  Xu Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... CREB (1:1000, Cell Signaling), FLAG (1:5000 ...
• Quantitative chromatin protein dynamics during replication origin firing in human cells

  Sampath Amitash Gadi, et al., bioRxiv - Cell Biology 2024

  Quote: ... pFOXM1 (1/500, Cell Signaling) and GFP (1/2000 ...
• NAD⁺ prevents septic shock-induced death by non-canonical inflammasome blockade and IL-10 cytokine production in macrophages

  Jasper Iske, et al., bioRxiv - Immunology 2024

  Quote: ... STAT-1 (#9172S, Cell Signaling), NF-κB-p65 (#49445S ...
• Human natural killer cells can activate NLRP1 and NLRP3 inflammasomes and drives pyroptosis

  Antonio Astorga-Gamaza, et al., bioRxiv - Immunology 2024

  Quote: ... Caspase-1 (Cell signaling, 3866S), Gasdermin D (Santacruz ...
• Differential effects of diphenyl diselenide (PhSe)₂ on mitochondria-related pathways depending on the cellular energy status in Bovine Vascular Endothelial Cells

  Letícia Selinger Galant, et al., bioRxiv - Biochemistry 2024

  Quote: ... α-NRF2 (1:200, Cell signaling) or α-FOXO3 (1:100 ...
• Pathobiology of the autophagy-lysosomal pathway in the Huntington’s disease brain

  Martin J. Berg, et al., bioRxiv - Pathology 2024

  Quote: ... (1) from Cell Signaling Technology: tHTT rabbit mAb (clone D7F7 ...
• mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

  Philip Stavrides, et al., bioRxiv - Pathology 2024

  Quote: ... (1) from Cell Signaling Technology: tHTT rabbit mAb (total HTTs ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... eIF6 (1:1000; Cell Signaling), RPL23 (1:2500 ...
• Distinct Perception Mechanisms of BACH1 Quaternary Structure Degrons by Two F-box Proteins under Oxidative Stress

  Shiyun Cao, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Nrf2 (1:1000, Cell Signaling), Keap1 (1:10 000 ...
• Differential effects of diphenyl diselenide (PhSe)₂ on mitochondria-related pathways depending on the cellular energy status in Bovine Vascular Endothelial Cells

  Letícia Selinger Galant, et al., bioRxiv - Biochemistry 2024

  Quote: ... α-pFOXO3 (1:1000, Cell signaling), α-AKT (1:1000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... eIF4E (1:1000, Cell Signaling), 4EBP1 (1:1000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 4EBP1 (1:1000, Cell Signaling), 4EBP2 (1:1000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... eIF2α (1:1000, Cell Signaling), eIF2A (1:1000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... eIF4G1 (1:1000, Cell Signaling), topoisomerase IIβ (1:1000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... β-Tubulin (1:2500; Cell Signaling), GAPDH (1:6000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... β-Actin (1:10000, Cell Signaling), p53 (1:1000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Vinculin (1:1000; Cell Signaling), β-Actin (1:10000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... GAPDH (1:6000, Cell Signaling), Vinculin (1:1000 ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 4EBP2 (1:1000, Cell Signaling), eIF2α (1:1000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-STING (1:1000; Cell Signaling), α-RIG-I (1:1000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-NEMO (1:500, Cell Signaling), and α-V5 (1:1000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-TBK1 (1:1000; Cell Signaling), α-pSTAT1 (1:1000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-STAT2 (1:1000; Cell Signaling), α-IRF9 (1:1000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-IRF9 (1:1000; Cell Signaling), α-NEMO (1:500 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-IRF3 (1:1000; Cell Signaling), α-TBK1 (1:1000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-pSTAT1 (1:1000; Cell Signaling), α-STAT1 (1:000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-pSTAT2 (1:1000; Cell Signaling), α-STAT2 (1:1000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-STAT1 (1:000; Cell Signaling), α-pSTAT2 (1:1000 ...
• Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

  Denise Ohnezeit, et al., bioRxiv - Molecular Biology 2024

  Quote: ... α-H3K27me3 (1:300; Cell Signaling), α-H3K9me3 (1:200 ...
• AAV-DJ is Superior to AAV9 for Targeting Brain and Spinal Cord, and De-Targeting Liver Across Multiple Delivery Routes in Mice

  Monika Chauhan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1:100 (#4604, Cell Signaling). After a 5 min 1x PBS rinse ...
• Differential effects of diphenyl diselenide (PhSe)₂ on mitochondria-related pathways depending on the cellular energy status in Bovine Vascular Endothelial Cells

  Letícia Selinger Galant, et al., bioRxiv - Biochemistry 2024

  Quote: ... α-AKT (1:1000, Cell signaling), α-pAKT (1:1000 ...
• Differential effects of diphenyl diselenide (PhSe)₂ on mitochondria-related pathways depending on the cellular energy status in Bovine Vascular Endothelial Cells

  Letícia Selinger Galant, et al., bioRxiv - Biochemistry 2024

  Quote: ... α-pAKT (1:1000, Cell signaling), α-MnSOD (1:3000 ...
• Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

  Abdulkadir Ozkan, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:100 (Cell Signaling, 3169); mouse anti-PSA-NCAM ...
• Gut microbial metabolite imidazole propionate impairs endothelial cell function and promotes the development of atherosclerosis

  Vanasa Nageswaran, et al., bioRxiv - Systems Biology 2024

  Quote: ... FOXO1 (Cell Signaling, 1:2000) and GAPDH (Merck ...