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3251 - 3300 of 10000+ citations for 7 Methyl 1 5 dioxo 1 2 3 5 tetrahydro indolizine 6 carbonitrile since 2019

• Changing the Waddington landscape to control mesendoderm competence

  James R. Valcourt, et al., bioRxiv - Developmental Biology 2020

  Quote: ... phosphorylated-SMAD2 (1:200, Cell Signaling E8F3R); PAX6 (1:200 ...
• Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

  Amanda M. Rampersaud, et al., bioRxiv - Developmental Biology 2020

  Quote: ... calponin (D8L2T, 1:1000, Cell Signaling Technology), transgelin (SC-53932 ...
• Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

  Amanda M. Rampersaud, et al., bioRxiv - Developmental Biology 2020

  Quote: ... calponin (D8L2T, 1:50, Cell Signaling Technology), or transgelin (sc-53932 ...
• Tripartite Inhibition of SRC-WNT-PKC Signalling Consolidates Human Naïve Pluripotency

  Jonathan Bayerl, et al., bioRxiv - Developmental Biology 2020

  Quote: ... RBPJ (C5 5313, 1:1000, Cell Signaling), TFAP2C (CSTH2320 ...
• Myogenin is an Essential Regulator of Adult Myofibre Growth and Muscle Stem Cell Homeostasis

  Massimo Ganassi, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Akt (pan) (1:1000; #4685; Cell Signaling), Actin (1:500 ...
• Mitochondrial fusion regulates proliferation and differentiation in the type II neuroblast lineage in Drosophila

  Dnyanesh Dubal, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-cleaved Caspase3 (1:100, Cell Signaling), anti-phosphohistone 3 (1:100 ...
• SPEN is Required for Xist Upregulation during Initiation of X Chromosome Inactivation

  Teresa Robert-Finestra, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 1 μg of antibody (Cell Signaling, 9733S) was conjugated with 25 μL magnetic beads (Life Technologies ...
• Transcriptomic and genetic analyses identify the Krüppel-like factor dar1 as a master regulator of tube-shaped long tendon development

  Laurichesse Quentin, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-Dcp1 (1:100, Cell Signaling), rabbit anti-pH3 (1:1000 ...
• LKB1 acts as a critical brake for the glucagon-mediated fasting response

  Suehelay Acevedo-Acevedo, et al., bioRxiv - Physiology 2022

  Quote: ... β-tubulin (2146S, 1:1000; Cell Signaling Technologies); phosphoenolpyruvate carboxykinase 1 (PCK1 [ab28455] ...
• Coupled myovascular expansion directs cardiac growth and regeneration

  Paige DeBenedittis, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-Actinin (Cell Signaling, 6487P, 1:100), anti-Tnnt (DSHB CT3 ...
• Progenitor cell integration into a barrier epithelium during adult organ turnover

  Paola Moreno-Roman, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Phospho4EBP1 (1:500, Cell Signaling). Secondary antibodies ...
• Comprehensive analysis of hsa-miR-654-5p’s tumor-suppressing functions

  Chuanyang Liu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... EMT kit (Cell Signaling Technology, 1:2000), beta-actin (Santa Cruz Biotech,1:4000) ...
• Neuronal hemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein

  Santulli Chiara, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-MYC 1:250 (Cell Signaling, 2276), anti-α-syn (C-20 ...
• Dopamine ameliorates hyperglycemic memory-induced vascular dysfunction in diabetic retinopathy

  Yeon-Ju Lee, et al., bioRxiv - Biochemistry 2022

  Quote: ... cytochrome c (1:500, Cell Signaling Technology), or β-actin (1:2000 ...
• Synaptic Activity-Dependent Changes in the Hippocampal Palmitoylome

  Glory Nasseri, et al., bioRxiv - Neuroscience 2021

  Quote: ... VGLUT1 (1:1,000; Cell Signaling Technologies 2102S). IgG-horseradish peroxidase-conjugated antibodies were obtained from Bio-Rad (Hercules ...
• Synaptic Activity-Dependent Changes in the Hippocampal Palmitoylome

  Glory Nasseri, et al., bioRxiv - Neuroscience 2021

  Quote: ... Smpd3 (1:500; Cell Signaling Technology C29F4), Synaptic vesicle protein 2A (1:500 ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Smad3 (Cell Signaling, 9523T, 1:1000); anti-phospho-Smad3 (Ser423/425 ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Smad2 (Cell Signaling, 5339T, 1:1000); anti-phospho-Smad2 (Ser465/467 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 4E-BP1 (1:1000; Cell Signaling, Cat#), p-eEF2 (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... PSD-95 (1:1000; Cell Signaling, Cat#), Synapsin2 (1:1000 ...
• Endothelial cell polarity and extracellular matrix production rely on functional ATP6AP2 during developmental and pathological angiogenesis

  NR Patel, A Blanks, Y Li, MC Prieto, SM Meadows, bioRxiv - Molecular Biology 2021

  Quote: ... and GM130 (Cell signaling, 12480, 1:100).
• Endothelial cell polarity and extracellular matrix production rely on functional ATP6AP2 during developmental and pathological angiogenesis

  NR Patel, A Blanks, Y Li, MC Prieto, SM Meadows, bioRxiv - Molecular Biology 2021

  Quote: ... anti-Parvin (Cell signaling, 8190, 1:1000).
• Opposing roles of p38α-mediated phosphorylation and arginine methylation in driving TDP-43 proteinopathy

  Mari Aikio, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1 µg/mL leupeptin] (Cell Signaling Technology), supplemented with protease inhibitors (cOmplete ...
• A CellAgeClock for expedited discovery of anti-ageing compounds

  Celia Lujan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... pS6K (Cell Signaling Technology; 1:1000; 9206S), total S6K (Santa Cruz ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... eIF2α (Cell Signaling Technologies; 9722S; 1:500), G3BP1 (Proteintech ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... VPS35 (Cell Signaling Technologies; 81453S; 1:500), eIF2α (Cell Signaling Technologies ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... eIF2α (Cell Signaling Technologies; 9722S; 1:500), G3BP1 (Proteintech ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... GAPDH (Cell Signaling Technologies; 2118; 1:10,000), and H3 (Millipore ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... VPS35 (Cell Signaling Technologies; 81453S; 1:1000), eIF2α (Cell Signaling Technologies ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... UPF1 (Cell Signaling Technologies; 12040S; 1:1000), MOV10 (Proteintech ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... PABP1 (Cell Signaling Technologies; 4992S; 1:1000), CLTA (Proteintech ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... PABP1 (Cell Signaling Technologies; 4992S; 1:500), CLTA (Proteintech ...
• Myotube hypertrophy is associated with cancer-like metabolic reprogramming and limited by PHGDH

  Lian E.M. Stadhouders, et al., bioRxiv - Molecular Biology 2020

  Quote: ... pan-ACTIN (1:1000, Cell Signaling Technology, Cat# 8456 ...
• S-Palmitoylation-Dependent Regulation of Cardiomyocyte Rac1 Signaling Activity and Cardiac Hypertrophy

  Matthew J. Brody, et al., bioRxiv - Molecular Biology 2021

  Quote: ... PAK1 (Cell Signaling Technology, #2602, 1:500), H-Ras (Santa Cruz Biotechnology ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/1000 ubiquitin (Cell Signaling Technologies, 3393S); 1/1000 K48-linked polyubiquitin (Cell Signaling Technologies ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/1000 Atf4 (Cell Signaling Technologies, 11815); 1/1000 ubiquitin (Cell Signaling Technologies ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/1000 eif2a (Cell Signaling Technologies, 9722) 1/3000 puromycin (Millipore Simga MABE343) ...
• The AAA-ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle

  Dina Aweida, Shenhav Cohen, bioRxiv - Cell Biology 2022

  Quote: ... calpain-1 (for immunoblotting) from Cell Signaling, anti-phospho-Threonine/Serine from ECM Biosciences ...
• Prom1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium

  Carlos F. H. Serra, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-RBPSUH (Cell Signaling #5313, 1:100), anti-UGRP1 (R&D Systems ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ULK1 (1:200, Cell Signaling); goat anti-ATG14 (1:50 Santa Cruz Biotech.) ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG13 (1:1000, Cell Signaling); rabbit anti-ATG101 (1:1000 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG14 (1:1000, Cell Signaling); rabbit anti-ATG13 (1:1000 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG13 (1:100, Cell Signaling); rabbit anti-ULK1 (1:200 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-FIP200 (1:200, Cell Signaling); rabbit anti-ATG13 (1:100 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG9A (1:1000, Cell Signaling); rabbit anti-ATG14 (1:1000 ...
• FIP200 organizes the autophagy machinery at p62-ubiquitin condensates beyond activation of the ULK1 kinase

  Eleonora Turco, Irmgard Fischer, Sascha Martens, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ATG9 (1:100, Cell Signaling); rabbit anti-p62 phS349 (1:100 ...
• A critical role for E2-p53 interaction during the HPV16 life cycle

  Christian T. Fontan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:1000(Cell Signaling; cat. No. 2360), CHK2 ...
• A critical role for E2-p53 interaction during the HPV16 life cycle

  Christian T. Fontan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:1000 (Cell Signaling; cat. No. 2661S), CHK1 ...
• Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase

  Xuan Mo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Stat3 (124H6, 1:1000, Cell Signaling Technology), pStat3 (Y705 ...
• Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase

  Xuan Mo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Mitf (D5G7V, 1:1000, Cell Signaling Technology), Pmel/gp100 (EP4863(2) ...