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201 - 250 of 10000+ citations for N 5 Trimethoxysilyl 2 Aza 1 Oxopentyl Caprolactam since 2020

• Optimized transcriptional signature for evaluation of MEK/ERK pathway baseline activity and long-term modulations in ovarian cancer

  Mikhail S. Chesnokov, Anil Yadav, Ilana Chefetz, bioRxiv - Cancer Biology 2022

  Quote: ... total ERK1/2 (Cell Signaling Technology, 137F5, 1:1000), pp90RSK1 (R&D Systems ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling technology; #4695, 1:1,000), anti-active β-Catenin (Cell signaling technology ...
• Nicotinamide mononucleotide treatment increases NAD+ levels in an iPSC Model of Parkinson’s Disease

  Brett K. Fulleylove-Krause, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-SIRT 2 (Cell Signaling, 12672, 1:1000), rabbit anti-SIRT 3 (Abgent ...
• Presenilin-deficient neurons and astrocytes display normal mitochondrial phenotypes

  Sabrina Contino, et al., bioRxiv - Neuroscience 2020

  Quote: ... Anti-Presenilin 2 (1:1,000; Cell Signaling, Danvers, USA); Anti-Tubulin (1:3000 ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling 4695, 1:2000), rabbit anti-phospho-PAK1 (S199/S204 ...
• Exploiting KRAS-driven Ferroaddiction in Cancer Through Ferrous Iron-Activatable Drug Conjugates (FeADC)

  Honglin Jiang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Erk1/2 (Cell Signaling Technology, 4696, Dilution: 1:1000); GAPDH (Cell Signaling Technology ...
• Rewiring of the TCR signalosome in natural intestinal Intraepithelial T lymphocytes drives non-deletional tolerance

  Harriet J. Watt, et al., bioRxiv - Immunology 2023

  Quote: ... SHP-1 or SHP-2 (all Cell Signaling Technology) followed by anti-rabbit Dylight649 (1:500 ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... ERK1/2 (1:1000, Cell Signaling Technology, Cat# 9102), phospho-p38 (Thr180/Tyr182 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... ERK1/2 (1:1000; 9102; Cell Signaling Technology, Inc.); phospho-AKT (Ser473 ...
• Neural stem cells protect blood-brain barrier integrity via the p38, JNK, and ERK1/2 pathways following intracerebral hemorrhage in rats

  Jing Sun, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-ERK1/2 (Cell Signaling, USA, 1:1000 dilution), anti-p38 (Cell Signaling ...
• Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis

  Abir Mukherjee, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HK-2 (Cell Signaling Technology, cat# 2867, 1:1000), p-STAT3 Tyr 708 (Cell Signaling Technology ...
• Acquired and intrinsic resistance to vemurafenib in BRAF^V600E-driven melanoma brain metastases

  Ping Zhang, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... phospho-ERK1/2 (1:200; 4370; Cell Signaling Technology), phospho-AKT (1:8,000 ...
• Competitive, connective and allosteric Nanobodies that modulate the SOS1•RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design

  Baptiste Fischer, et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit monoclonal ERK1/2 (1:50, Cell Signaling #4696), and mouse monoclonal Flag antibody (clone M2 ...
• Peripheral extracellular vesicle-derived miR-150-3p exacerbates acute kidney injury following acute pancreatitis by promoting ferroptosis through FTH1 signaling

  Ji-tao Cui, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Cox-2 (1:1,000, 9461, Cell Signaling Technology), anti-β-actin (1:2,000 ...
• Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation

  Eun Hye Park, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERK1/2 (Cell Signaling Technology, Cat.No.9102S, 1:1000), phospho-4EBP1 (Cell Signaling Technology ...
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  Tiantian Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Mek1/2 (1:1,000, Cell Signaling Technology, Cat# 9122), alpha-tubulin (Sigma ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-MAPKAPK-2 (1:1000, Cell Signaling 3042), rabbit anti-phospho-MAPKAPK-2 (Thr222 ...
• Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

  Lorenz Waltl, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-MEK1/2 (1:1000; # 9122; Cell Signaling), rabbit anti-phospho-MEK1/2 (1:1000 ...
• Multifunctional molecular hybrid for targeted colorectal cancer cells: Integrating doxorubicin, AS1411 aptamer, and T9/U4 ASO

  Kanpitcha Jiramitmongkon, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Bcl–2 (1:1000; 25 – 28 kDa, Cell signaling), and Bax (1:1000 ...
• Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression

  Nathaniel Shannon, et al., bioRxiv - Cell Biology 2024

  Quote: ... total MEK1/2 (1:1000, Cell Signaling Technology #9122), Cofilin (1:1000 ...
• The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

  Patience O. Obi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-Bcl-2 (3498, Cell Signaling, 1:1000), rabbit anti-Bax (2772 ...
• XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

  Andrew E. Evans, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-COX-2 (1/300; Cell Signaling, Cat# 12282S), anti-Ki67 (1/200 ...
• XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

  Andrew E. Evans, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-COX-2 (1/1000; Cell Signaling, Cat # 12282S), anti-Actin (1/5000 ...
• THE STABILIZATAION OF C-MYC BY THE NOVEL CELL CYCLE REGULATOR, SPY1, DECREASES EFFICACY OF BREAST CANCER TREATMENTS

  Rosa-Maria Ferraiuolo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-p-ERK 1/2 [Thr 202/Tyr 204] (Cell Signaling; 1:1000), and anti-ERK1/2 (Santa Cruz Biotechnology ...
• V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis

  Miriam Formica, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-p-ERK 1/2 (Thr202/Tyr204) 1:1000 (4370, Cell Signaling), rabbit anti-ERK 1/2 1:1000 (4695 ...
• Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling

  Mehrnaz Mehrabipour, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-ERK(1/2) (1:1000; #9102, Cell Signaling, Frankfurt am Main, Germany); anti-p-ERK(1/2 ...
• ALK signaling drives tumorigenicity and chemoresistance of pancreatic ductal adenocarcinoma cells

  Beatriz Parejo-Alonso, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK 1/2 (1:3000) (all from Cell Signaling Technology, Danvers, MA, USA), pERK 1/2 (T202-Y204 ...
• m⁶A RNA methylation orchestrates transcriptional dormancy during developmental pausing

  Evelyne Collignon, et al., bioRxiv - Developmental Biology 2023

  Quote: ... embryos were incubated overnight at 4°C with the primary antibodies (Mettl3 Abcam ab195352 1/200; N-Myc Cell Signaling Technology D1V2A 1/200). EU fluorescence coupling was performed following the manufacturer ’s instructions for Click-iT™ RNA Alexa Fluor 488 Imaging Kit ...
• Vitamin C functions as double-edge sword on cancer progression depending on ERK activation or inhibition mediated by its receptor SVCT2

  Yian Guan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-N-Cadherin (Cat#13116, Cell Signaling Technology), anti-Vimentin (Cat#10366-1-AP ...
• Hyperactivation of YAP/TAZ drives alterations in mesangial cells through stabilization of N-MYC in diabetic nephropathy

  Seunghyeok Choi, et al., bioRxiv - Pathology 2022

  Quote: ... anti-N-MYC (rabbit, polyclonal, Cell Signaling, 9405), anti-MYC (rabbit ...
• Highly multiplexed spatially resolved gene expression profiling of mouse organogenesis

  Tim Lohoff, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-N-Cadherin (Cell Signaling Technology, [13A9], 14215), anti-β-Catenin antibody (15B8 ...
• Chaperone-mediated Autophagy Deficiency Reprograms Cancer Metabolism Via TGFβ Signaling to drive Mesenchymal Tumor Growth

  Xun Zhou, et al., bioRxiv - Cancer Biology 2022

  Quote: ... N-Cadherin (Cell Signaling, D4R1H; Santa Cruz, sc59987,), Vimentin (Cell Signaling ...
• OrganoLabeling: Quick and accurate annotation tool for organoid images

  Burak Kahveci, et al., bioRxiv - Bioengineering 2024

  Quote: ... N-cadherin (Cell Signaling Technology, Cat no. 13116T) were added according to related samples and incubated for overnight at 4 °C ...
• Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

  Qian Wang, et al., bioRxiv - Developmental Biology 2024

  Quote: ... N-cadherin (#13116) (all from Cell Signaling Technology), Fibronectin (AB2033 ...
• T_reg cells drive MYCN-mediated immunosuppression and tumor aggressiveness in high-risk neuroblastoma

  Xiaodan Qin, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The primary antibodies include anti-N-MYC (1:160 dilution, clone D4B2Y, Cell Signaling Technology, 51705; citrate antigen retrieval) and anti-FOXP3 (1:50 dilution ...
• CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors

  Joel Rüegger, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Membranes were incubated with primary antibody rabbit-anti-FES (85704, Cell Signaling Technologies, 1:1000, o/n, 4 °C) in 5% (w/v ...
• Optimized transcriptional signature for evaluation of MEK/ERK pathway baseline activity and long-term modulations in ovarian cancer

  Mikhail S. Chesnokov, Anil Yadav, Ilana Chefetz, bioRxiv - Cancer Biology 2022

  Quote: ... and probed overnight at 4°C with the following primary antibodies diluted in 5% BSA in TBST: pMEK1/2 (Cell Signaling Technology, Danvers, MA, USA, 41G9, 1:1000), pERK1/2 (Cell Signaling Technology ...
• S-Palmitoylation-Dependent Regulation of Cardiomyocyte Rac1 Signaling Activity and Cardiac Hypertrophy

  Matthew J. Brody, et al., bioRxiv - Molecular Biology 2021

  Quote: ... p-extracellular signal-regulated kinase (ERK) 1/2 (Cell Signaling Technology, #4370, 1:500), ERK1/2 (Cell Signaling Technology ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... phospho-ERK 1/2 Y202/204 1:2000 (Cell Signaling Technology Cat# 4370, RRID:AB_2315112), ERK 1:1000 (Cell Signaling Technology Cat# 4695 ...
• Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling

  Mehrnaz Mehrabipour, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-p-ERK(1/2) (1:1000; #4370, Cell Signaling, Frankfurt am Main, Germany); anti-KRAS (1:1000 ...
• Synthesis of ionizable lipopolymers using split-Ugi reaction for pulmonary delivery of various size RNAs and gene editing

  K. Yu. Vlasova, et al., bioRxiv - Bioengineering 2024

  Quote: ... cycle 2 Rabbit E-Cadherin (Cell Signaling, 24E10 #3195, dilution 1:200, 1 h), cycle 3 Rabbit CD31 (Abcam ...
• Regulation of early growth response-1 (Egr-1) gene expression by Stat1-independent type I interferon signaling and respiratory viruses

  Chilakamarti V. Ramana, bioRxiv - Genomics 2020

  Quote: ... and subjected to immunoblotting with the antibodies for phosphorylated Erk-1/2 (Thr202/Tyr 204) or total Erk-1/2 from Cell Signaling Technology (Beverly, MA). Blots were visualized by enhanced chemiluminescence western detection system (Pierce ...
• Syndecan-4^-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

  Sissel Beate Rønning, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-pSer240/244-RPS6 (1:1000, 5% BSA, #5364 Cell Signaling), anti-pSer473-Akt (1:500 ...
• Neuron-radial glial cell communication via BMP/Id1 signaling maintains the regenerative capacity of the adult zebrafish telencephalon

  Gaoqun Zhang, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-Phospho Smad1/5/9 (1:200, Cell Signaling Technology) and rabbit anti-RFP (1:500 ...
• Stress-induced vascular remodeling: novel insight into the role of omega-3 fatty acid metabolite, 4-oxoDHA

  Makoto Nishimori, et al., bioRxiv - Biochemistry 2023

  Quote: ... Antibodies against rabbit anti-5-lipoxygenase (1:1000, Cell Signaling, #C49G1), rabbit anti-NRF2 (1:500 ...
• The anatomy of transcriptionally active chromatin loops in Drosophila primary spermatocytes using super-resolution microscopy

  Madeleine L. Ball, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 1:500 and rabbit anti-RPol-PSer2/5 (47355, Cell Signaling); 1:500 ...
• Essential role of the amino-terminal region of Drosha for the Microprocessor function

  Amit Prabhakar, et al., bioRxiv - Molecular Biology 2022

  Quote: ... phospho-Smad1/5/8 (1:100 dilution, Cell signaling Technology, 9511), anti-β-actin (1:5000 dilution ...
• Targeting of MMP-13 prevents aortic aneurysm formation in Marfan mice

  Laura-Marie A. Zimmermann, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-phospho-SMAD1/5/8 (#9511, Cell Signaling, WB: 1:1000), anti-BMP-7 GF (#500-P198 B ...
• Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV

  Stephanie M. Matt, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-NLRC4 antibody (12421, 1:1000 in 5% BSA, Cell Signaling) or anti-AIM2 antibody (MA5-38442 ...
• Construction of an embryonic caudal organizer by BMP4

  Yan-Yi Xing, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Anti-pSmad1/5/9 antibody (13820, Cell Signaling Technologies, 1:800), anti-SOX2 antibody (AF2018 ...